AT372384B - Verfahren zur herstellung von neuen indol-(2,3-a)-chinolizidinen und ihren saeureadditionssalzen - Google Patents

Verfahren zur herstellung von neuen indol-(2,3-a)-chinolizidinen und ihren saeureadditionssalzen

Info

Publication number
AT372384B
AT372384B AT0837478A AT837478A AT372384B AT 372384 B AT372384 B AT 372384B AT 0837478 A AT0837478 A AT 0837478A AT 837478 A AT837478 A AT 837478A AT 372384 B AT372384 B AT 372384B
Authority
AT
Austria
Prior art keywords
chinolizidines
acid addition
addition salts
producing new
new indol
Prior art date
Application number
AT0837478A
Other languages
German (de)
English (en)
Other versions
ATA837478A (de
Inventor
Andre Buzas
Original Assignee
Scras
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scras filed Critical Scras
Publication of ATA837478A publication Critical patent/ATA837478A/de
Application granted granted Critical
Publication of AT372384B publication Critical patent/AT372384B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
AT0837478A 1977-11-25 1978-11-23 Verfahren zur herstellung von neuen indol-(2,3-a)-chinolizidinen und ihren saeureadditionssalzen AT372384B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4920177 1977-11-25

Publications (2)

Publication Number Publication Date
ATA837478A ATA837478A (de) 1983-02-15
AT372384B true AT372384B (de) 1983-09-26

Family

ID=10451538

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0837478A AT372384B (de) 1977-11-25 1978-11-23 Verfahren zur herstellung von neuen indol-(2,3-a)-chinolizidinen und ihren saeureadditionssalzen

Country Status (28)

Country Link
JP (1) JPS6147838B2 (da)
AR (1) AR218514A1 (da)
AT (1) AT372384B (da)
AU (1) AU529108B2 (da)
BE (1) BE872134A (da)
CA (1) CA1100959A (da)
CH (1) CH641181A5 (da)
DE (1) DE2851028A1 (da)
DK (1) DK154430C (da)
EG (1) EG13683A (da)
ES (1) ES475328A1 (da)
FI (1) FI64372C (da)
FR (2) FR2409755A1 (da)
HK (1) HK60884A (da)
IE (1) IE47518B1 (da)
IN (1) IN151146B (da)
IT (1) IT1160263B (da)
LU (1) LU80576A1 (da)
MX (1) MX5529E (da)
MY (1) MY8500029A (da)
NL (1) NL7811562A (da)
NO (1) NO151288C (da)
NZ (1) NZ188974A (da)
PT (1) PT68825A (da)
SE (2) SE431650B (da)
SG (1) SG61182G (da)
WO (1) WO1979000319A1 (da)
ZA (1) ZA786426B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3175900D1 (en) * 1981-11-18 1987-03-12 Thal Claude Indoloquinolizine derivatives, process for their preparation and their therapeutic use
FR2529552B1 (fr) * 1982-07-05 1985-09-27 Centre Nat Rech Scient Nouveau procede de preparation d'intermediaires de synthese de la vindoline et intermediaires de synthese
HU191454B (en) * 1984-10-05 1987-02-27 Richter Gedeon Vegyeszeti Gyar Rt.,Hu Process for producing amides of oktahydro-indolo/2,3-a/quinolyzin-1-yl-alkanecarboxylic acids and pharmaceutically acceptable acid additional salts thereof
HU195214B (en) * 1985-04-19 1988-04-28 Richter Gedeon Vegyeszet Process for producing 12b-substituted-1-(hydroxymethyl)-octahydro-indolo /2,3-a/ quinolizine derivatives and pharmaceutical preparations comprising these compounds
HU194220B (en) * 1985-04-19 1988-01-28 Richter Gedeon Vegyeszet Process for production of derivatives of 1,12 b disubstituated-octahydro-indolo /2,3-a/ quinolisine and medical compounds containing thereof
FI95572C (fi) 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
WO1995000502A1 (fr) * 1993-06-18 1995-01-05 Fujisawa Pharmaceutical Co., Ltd. Nouvel intermediare pour utilisation et traitement de synthese de production d'un derive d'aminopiperazine
FR2713644B1 (fr) * 1993-12-14 1996-02-09 Adir Nouveaux analogues de l'éburnane, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
FR2713643B1 (fr) * 1993-12-14 1996-06-07 Adir Nouveaux analogues de l'éburnane, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
PT1532391E (pt) † 2002-06-24 2009-06-25 Saint Gobain Isover Painel de isolamento para conduta de distribuição
FR2911143A1 (fr) * 2007-01-05 2008-07-11 Servier Lab Utilisation de composes neuroprotecteurs pour l'obtention de medicaments destines au traitement de maladies neurodegeneratives.
FR2911141B1 (fr) * 2007-01-05 2009-02-20 Servier Lab Nouveaux derives triazabenzo[a]naphtho[2,1,8-cde]azulene, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2911142A1 (fr) * 2007-01-05 2008-07-11 Servier Lab Nouveaux derives aminopyrrolo[1,2-a]indole et aminopyridazino[1,6-a]indole,leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU167366B (da) * 1972-09-06 1975-09-27
BE802387A (fr) * 1973-07-16 1973-11-16 Omnium Chimique Sa Procede de preparation de la vincamone et de l'epi-21 vincamone a partir de la tabersonine et derives indoliques nouveaux.
HU169916B (da) * 1974-09-27 1977-02-28
HU171165B (hu) * 1974-11-26 1977-11-28 Richter Gedeon Vegyeszet Sposob poluchenija proizvodnykh oktagidro-indolo-skobka-2,3-a-skobka zakryta-kinolizina
FR2315277A1 (fr) * 1975-06-25 1977-01-21 Anvar Nouveaux derives pentacycliques, leur preparation et les compositions qui les contiennent

Also Published As

Publication number Publication date
CH641181A5 (fr) 1984-02-15
ES475328A1 (es) 1979-04-01
SG61182G (en) 1985-02-15
AU4187478A (en) 1979-05-31
BE872134A (fr) 1979-03-16
IT1160263B (it) 1987-03-11
MX5529E (es) 1983-09-23
SE8007845L (sv) 1980-11-07
FR2423492B1 (da) 1980-12-05
FR2409755B1 (da) 1980-08-01
AU529108B2 (en) 1983-05-26
FR2409755A1 (fr) 1979-06-22
DE2851028A1 (de) 1979-05-31
JPS54500053A (da) 1979-11-08
IT7830171A0 (it) 1978-11-24
DK154430C (da) 1989-04-17
FR2423492A1 (fr) 1979-11-16
CA1100959A (en) 1981-05-12
DK154430B (da) 1988-11-14
WO1979000319A1 (fr) 1979-06-14
AR218514A1 (es) 1980-06-13
IN151146B (da) 1983-02-26
JPS6147838B2 (da) 1986-10-21
IE47518B1 (en) 1984-04-04
NO151288B (no) 1984-12-03
NO151288C (no) 1985-03-13
NL7811562A (nl) 1979-05-29
SE435622B (sv) 1984-10-08
LU80576A1 (fr) 1979-03-22
PT68825A (en) 1978-12-01
NO783958L (no) 1979-05-28
IE782328L (en) 1979-05-25
FI64372B (fi) 1983-07-29
ZA786426B (en) 1979-10-31
EG13683A (en) 1982-09-30
SE431650B (sv) 1984-02-20
ATA837478A (de) 1983-02-15
FI783581A (fi) 1979-05-26
SE7906287L (sv) 1979-07-23
HK60884A (en) 1984-08-10
MY8500029A (en) 1985-12-31
NZ188974A (en) 1989-10-27
DE2851028C2 (da) 1990-05-03
FI64372C (fi) 1983-11-10
DK524978A (da) 1979-05-26

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