AT344333B - Verfahren zur herstellung von neuen 8-thiomethylergolinen - Google Patents
Verfahren zur herstellung von neuen 8-thiomethylergolinenInfo
- Publication number
- AT344333B AT344333B AT427975A AT427975A AT344333B AT 344333 B AT344333 B AT 344333B AT 427975 A AT427975 A AT 427975A AT 427975 A AT427975 A AT 427975A AT 344333 B AT344333 B AT 344333B
- Authority
- AT
- Austria
- Prior art keywords
- thiomethylergolines
- producing new
- producing
- new
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US477136A US3901894A (en) | 1974-06-06 | 1974-06-06 | 8-thiomethylergolines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA427975A ATA427975A (de) | 1977-11-15 |
| AT344333B true AT344333B (de) | 1978-07-10 |
Family
ID=23894677
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT427975A AT344333B (de) | 1974-06-06 | 1975-06-05 | Verfahren zur herstellung von neuen 8-thiomethylergolinen |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US3901894A (nl) |
| JP (1) | JPS582946B2 (nl) |
| AR (1) | AR210736A1 (nl) |
| AT (1) | AT344333B (nl) |
| AU (1) | AU507574B2 (nl) |
| BE (1) | BE829887A (nl) |
| BG (1) | BG24812A3 (nl) |
| CA (1) | CA1071623A (nl) |
| CH (1) | CH617196A5 (nl) |
| CS (1) | CS199591B2 (nl) |
| DD (1) | DD120438A5 (nl) |
| DE (1) | DE2524575A1 (nl) |
| DK (1) | DK144160C (nl) |
| ES (1) | ES438313A1 (nl) |
| FR (1) | FR2273542A1 (nl) |
| GB (1) | GB1505296A (nl) |
| HU (1) | HU173590B (nl) |
| IE (1) | IE41474B1 (nl) |
| IL (1) | IL47424A (nl) |
| NL (1) | NL180911C (nl) |
| PH (1) | PH10992A (nl) |
| PL (1) | PL95738B1 (nl) |
| RO (1) | RO77543A (nl) |
| SE (1) | SE420095B (nl) |
| SU (1) | SU613724A3 (nl) |
| YU (1) | YU145575A (nl) |
| ZA (1) | ZA753638B (nl) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4147789A (en) * | 1974-03-14 | 1979-04-03 | Sandoz Ltd. | 6-Methyl-8-thiomethyl-ergolene derivatives |
| US3959288A (en) * | 1974-12-13 | 1976-05-25 | Eli Lilly And Company | 8-Oxymethylergolines and process therefor |
| JPS5283894A (en) * | 1976-01-01 | 1977-07-13 | Lilly Co Eli | 88thiomethyl ergoline |
| GB1549829A (en) * | 1976-05-26 | 1979-08-08 | Farmaceutici Italia | 10'-methoxy-1',6'-dimethylergoline-8'-beta-methyl-amino(or thio)-pyrazines |
| IT1192260B (it) * | 1977-07-05 | 1988-03-31 | Simes | Derivati di ergoline-2-tioeteri e loro solfossidi |
| US4166182A (en) * | 1978-02-08 | 1979-08-28 | Eli Lilly And Company | 6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds |
| US4180582A (en) * | 1978-02-08 | 1979-12-25 | Eli Lilly And Company | 6-n-Propyl-8-methoxy-methyl or methylmercaptomethylergolines and related compounds as prolactin inhibitors and to treat Parkinson's syndrome |
| US4202979A (en) * | 1979-01-11 | 1980-05-13 | Eli Lilly And Company | 6-Ethyl(or allyl)-8-methoxymethyl or methylmercaptomethylergolines and related compounds |
| US4246265A (en) * | 1979-10-01 | 1981-01-20 | Eli Lilly And Company | 6-n-Propyl-8α-methoxymethyl or methylmercaptomethylergolines and related compounds |
| US4382940A (en) * | 1979-12-06 | 1983-05-10 | Farmitalia Carlo Erba S.P.A. | Ercoline derivatives and therapeutic compositions having CNS affecting activity |
| DE3216870A1 (de) * | 1982-05-03 | 1983-11-03 | Schering AG, 1000 Berlin und 4709 Bergkamen | Pharmazeutische zubereitungen mit zytostatischer wirkung |
| FR2526797A1 (fr) * | 1982-05-12 | 1983-11-18 | Roussel Uclaf | Nouveaux derives de l'acide 9-oxalysergique, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant |
| CH649998A5 (de) * | 1982-08-09 | 1985-06-28 | Sandoz Ag | Ergolinderivate, ein verfahren zu ihrer herstellung und heilmittel, enthaltend diese ergolinderivate als wirkstoff. |
| GB8427536D0 (en) * | 1984-10-31 | 1984-12-05 | Lilly Industries Ltd | Ergoline derivatives |
| US4675322A (en) * | 1984-12-10 | 1987-06-23 | Eli Lilly And Company | 1-Substituted-6-n-propyl-8β-methylthio-methylergolines |
| US4801712A (en) * | 1985-06-24 | 1989-01-31 | Eli Lilly And Company | 2-Alkyl(or phenyl)thio-6-n-alkylergolines are dopamine D-1 antagonists without D-2 agonist activity |
| FR2589734B1 (fr) * | 1985-11-13 | 1988-09-02 | Roussel Uclaf | Utilisation de derives de l'ergoline a l'obtention d'un medicament a visee geriatrique |
| HU196394B (en) * | 1986-06-27 | 1988-11-28 | Richter Gedeon Vegyeszet | Process for preparing 2-halogenated ergoline derivatives |
| ATE424414T1 (de) * | 2001-06-08 | 2009-03-15 | Sod Conseils Rech Applic | Chimere somatostatin-dopamin-analoga |
| US7019140B2 (en) * | 2002-03-15 | 2006-03-28 | Antibioticos S.P.A. | Process for the synthesis of pergolide |
| WO2014070965A2 (en) | 2012-11-01 | 2014-05-08 | Ipsen Pharma S.A.S | Somatostatin analogs and dimers thereof |
| TWI523863B (zh) | 2012-11-01 | 2016-03-01 | 艾普森藥品公司 | 體抑素－多巴胺嵌合體類似物 |
| NZ728804A (en) | 2014-09-25 | 2022-10-28 | Boehringer Ingelheim Vetmedica Gmbh | Combination treatment of sglt2 inhibitors and dopamine agonists for preventing metabolic disorders in equine animals |
| WO2019234069A1 (en) | 2018-06-08 | 2019-12-12 | Boehringer Ingelheim Vetmedica Gmbh | Liquid pharmaceutical compositions comprising pergolide |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE712054A (nl) * | 1967-03-16 | 1968-07-15 | ||
| DE1935556A1 (de) * | 1969-07-12 | 1971-01-21 | Hoechst Ag | Verfahren zur Herstellung von Lysergol |
| JPS5012398A (nl) * | 1973-06-08 | 1975-02-07 |
-
1974
- 1974-06-06 US US477136A patent/US3901894A/en not_active Expired - Lifetime
-
1975
- 1975-05-16 JP JP50059191A patent/JPS582946B2/ja not_active Expired
- 1975-06-03 CS CS753882A patent/CS199591B2/cs unknown
- 1975-06-03 IE IE1221/75A patent/IE41474B1/en unknown
- 1975-06-03 NL NLAANVRAGE7506584,A patent/NL180911C/nl not_active IP Right Cessation
- 1975-06-03 SE SE7506327A patent/SE420095B/xx not_active IP Right Cessation
- 1975-06-03 CA CA228,332A patent/CA1071623A/en not_active Expired
- 1975-06-03 DE DE19752524575 patent/DE2524575A1/de not_active Ceased
- 1975-06-03 GB GB23869/75A patent/GB1505296A/en not_active Expired
- 1975-06-03 PH PH17225A patent/PH10992A/en unknown
- 1975-06-03 HU HU75EI623A patent/HU173590B/hu unknown
- 1975-06-04 BG BG030188A patent/BG24812A3/xx unknown
- 1975-06-04 IL IL47424A patent/IL47424A/xx unknown
- 1975-06-04 AU AU81827/75A patent/AU507574B2/en not_active Expired
- 1975-06-04 DK DK249975A patent/DK144160C/da not_active IP Right Cessation
- 1975-06-04 PL PL1975180897A patent/PL95738B1/pl unknown
- 1975-06-05 RO RO7582445A patent/RO77543A/ro unknown
- 1975-06-05 FR FR7517652A patent/FR2273542A1/fr active Granted
- 1975-06-05 BE BE1006709A patent/BE829887A/xx not_active IP Right Cessation
- 1975-06-05 YU YU01455/75A patent/YU145575A/xx unknown
- 1975-06-05 SU SU752140862A patent/SU613724A3/ru active
- 1975-06-05 AT AT427975A patent/AT344333B/de not_active IP Right Cessation
- 1975-06-05 ZA ZA3638A patent/ZA753638B/xx unknown
- 1975-06-06 AR AR259118A patent/AR210736A1/es active
- 1975-06-06 CH CH731075A patent/CH617196A5/de not_active IP Right Cessation
- 1975-06-06 ES ES438313A patent/ES438313A1/es not_active Expired
-
1976
- 1976-06-05 DD DD186472A patent/DD120438A5/xx unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELJ | Ceased due to non-payment of the annual fee |