AT319948B - Verfahren zur Herstellung von neuen 2,4-Diamino-5-benzylpyrimidinen - Google Patents

Verfahren zur Herstellung von neuen 2,4-Diamino-5-benzylpyrimidinen

Info

Publication number
AT319948B
AT319948B AT909371A AT909371A AT319948B AT 319948 B AT319948 B AT 319948B AT 909371 A AT909371 A AT 909371A AT 909371 A AT909371 A AT 909371A AT 319948 B AT319948 B AT 319948B
Authority
AT
Austria
Prior art keywords
benzylpyrimidines
diamino
preparation
new
Prior art date
Application number
AT909371A
Other languages
German (de)
English (en)
Inventor
Roth Barbara
Stuart Alexander
Paterson Thomas
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Application granted granted Critical
Publication of AT319948B publication Critical patent/AT319948B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • C07D239/49Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT909371A 1970-10-22 1971-10-21 Verfahren zur Herstellung von neuen 2,4-Diamino-5-benzylpyrimidinen AT319948B (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB963871*[A GB1375162A (es) 1970-10-22 1970-10-22
GB963871 1971-04-16
GB4749171 1971-10-12

Publications (1)

Publication Number Publication Date
AT319948B true AT319948B (de) 1975-01-10

Family

ID=27255400

Family Applications (1)

Application Number Title Priority Date Filing Date
AT909371A AT319948B (de) 1970-10-22 1971-10-21 Verfahren zur Herstellung von neuen 2,4-Diamino-5-benzylpyrimidinen

Country Status (20)

Country Link
JP (2) JPS5536662B1 (es)
AR (3) AR192588A1 (es)
AT (1) AT319948B (es)
BE (1) BE774281A (es)
BG (4) BG20797A3 (es)
CA (1) CA967158A (es)
CH (3) CH568301A5 (es)
DD (1) DD100877A5 (es)
DK (1) DK132174C (es)
ES (1) ES396219A1 (es)
FI (1) FI56175C (es)
FR (1) FR2111769B1 (es)
GB (1) GB1375162A (es)
IE (1) IE37452B1 (es)
IL (2) IL45422A (es)
LU (1) LU64129A1 (es)
MC (1) MC894A1 (es)
NL (1) NL175178C (es)
SE (2) SE384505B (es)
ZM (1) ZM14971A1 (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE792096A (fr) * 1971-12-01 1973-05-30 Hoffmann La Roche Nouvelles benzylpyrimidines
FR2397407A2 (fr) * 1977-07-11 1979-02-09 Dick Pierre Derives de 2,4-diamino pyrimidines et leur mise en solution en association avec des sulfamides
IL57375A0 (en) * 1978-05-24 1979-09-30 Wellcome Found Benzylpyrimidines, their preparation and pharmaceutical compositions containing them
JPS61156909A (ja) * 1984-12-27 1986-07-16 Matsushita Electric Ind Co Ltd カレント・ミラ−回路
JPS62145907A (ja) * 1985-12-20 1987-06-30 Hitachi Ltd トランジスタ回路
TWI392678B (zh) 2004-03-26 2013-04-11 Dainippon Sumitomo Pharma Co 9-取代-8-氧基腺嘌呤化合物
JP2009542645A (ja) 2006-07-05 2009-12-03 アストラゼネカ・アクチエボラーグ Tlr7のモジュレーターとして作用する8−オキソアデニン誘導体
TW200831105A (en) 2006-12-14 2008-08-01 Astrazeneca Ab Novel compounds
US8067413B2 (en) 2007-03-19 2011-11-29 Astrazeneca Ab 9-substituted-8-oxo-adenine compounds as toll-like receptor (TLR7 ) modulators
WO2008114006A1 (en) 2007-03-19 2008-09-25 Astrazeneca Ab 9-substituted-8-oxo-adenine compounds as toll-like receptor (tlr7) modulators
WO2008114819A1 (ja) 2007-03-20 2008-09-25 Dainippon Sumitomo Pharma Co., Ltd. 新規アデニン化合物
PE20091236A1 (es) * 2007-11-22 2009-09-16 Astrazeneca Ab Derivados de pirimidina como immunomoduladores de tlr7
PE20091156A1 (es) 2007-12-17 2009-09-03 Astrazeneca Ab Sales de (3-{[[3-(6-amino-2-butoxi-8-oxo-7,8-dihidro-9h-purin-9-il)propil](3-morfolin-4-ilpropil)amino]metil}fenil)acetato de metilo
SG175796A1 (en) 2009-05-21 2011-12-29 Astrazeneca Ab Novel pyrimidine derivatives and their use in the treatment of cancer and further diseases
GB0908772D0 (en) 2009-05-21 2009-07-01 Astrazeneca Ab New salts 756
JP5978225B2 (ja) 2010-12-16 2016-08-24 大日本住友製薬株式会社 治療に有用なイミダゾ[4,5−c]キノリン−1−イル誘導体
EP2651943B1 (en) 2010-12-17 2017-03-22 Sumitomo Dainippon Pharma Co., Ltd. Purine derivatives
AU2013261267B2 (en) 2012-05-18 2017-06-29 Sumitomo Pharma Co., Ltd. Carboxylic acid compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE710100A (es) * 1967-02-02 1968-07-30
JPS511716A (ja) * 1974-06-25 1976-01-08 Toray Industries Horiesuterumaruchifuiramentono seiho

Also Published As

Publication number Publication date
DK132174B (da) 1975-11-03
IL37984A0 (en) 1971-12-29
FR2111769A1 (es) 1972-06-09
FI56175C (fi) 1979-12-10
GB1375162A (es) 1974-11-27
IL37984A (en) 1976-03-31
AR192802A1 (es) 1973-03-14
AR192803A1 (es) 1973-03-14
FR2111769B1 (es) 1974-10-18
BG20797A3 (es) 1975-12-20
BG20364A3 (es) 1975-11-05
ZM14971A1 (en) 1972-07-21
FI56175B (fi) 1979-08-31
BE774281A (fr) 1972-04-21
NL175178C (nl) 1984-10-01
JPS53135991A (en) 1978-11-28
IE37452B1 (en) 1977-08-03
IE37452L (en) 1972-04-22
CH582681A5 (es) 1976-12-15
SE384505B (sv) 1976-05-10
ES396219A1 (es) 1975-09-16
JPS5536662B1 (es) 1980-09-22
IL45422A (en) 1976-03-31
LU64129A1 (es) 1972-06-28
BG20365A3 (es) 1975-11-05
AR192588A1 (es) 1973-02-28
CH568301A5 (es) 1975-10-31
MC894A1 (fr) 1972-06-22
CA967158A (en) 1975-05-06
NL7114494A (es) 1972-04-25
BG21406A3 (es) 1976-05-20
SE409705B (sv) 1979-09-03
DD100877A5 (es) 1973-10-12
CH568302A5 (es) 1975-10-31
DK132174C (da) 1976-03-29
NL175178B (nl) 1984-05-01

Similar Documents

Publication Publication Date Title
CH553780A (de) Verfahren zur herstellung von neuen 1,4-dihydropyridinderivaten.
AT303040B (de) Verfahren zur Herstellung von neuen Azidophenyl-1,4-dihydroppyridinen
AT315856B (de) Verfahren zur herstellung von neuen 4-hydroxy-6-aryl-bzw.6-heteroarylpyrimidinen
AT319948B (de) Verfahren zur Herstellung von neuen 2,4-Diamino-5-benzylpyrimidinen
AT304530B (de) Verfahren zur Herstellung von neuen substituierten Phenyl-2-pyrrolidinonen
AT306238B (de) Verfahren zur Herstellung von neuen 3-Formylcephalosporinsulfoxyden
AT312606B (de) Verfahren zur Herstellung von neuen 2,2-Diaryl-4-piperidinbutyramiden
AT310953B (de) Verfahren zur Herstellung von neuen 8,9-Didehydro-10-alkoxyergolenderivaten
AT306010B (de) Verfahren zur Herstellung von neuen Nitrofuryl-triazolo-pyrimidinen
AT306260B (de) Verfahren zur Herstellung von neuen 3-Amino-cardenoliden
ATA1046871A (de) Verfahren zur herstellung von neuen 1-aminoisochinolinen
CH555332A (de) Verfahren zur herstellung von neuen 1,3,3-trisubstituierten 3-azolylpropinen.
CH545305A (de) Verfahren zur Herstellung von neuen 3-Guanidinoalkylthiophenen
AT300792B (de) Verfahren zur Herstellung von neuen modifizierten N,N'substituierten 2,4,5-Triketoimidazolidinen
AT306259B (de) Verfahren zur Herstellung von neuen 3-Oxo-11β,18-epoxy-17α-R-17β-hydroxyöstra-4,9-dienen
AT321271B (de) Verfahren zur Herstellung von neuen Phenylhydraziden
AT299945B (de) Verfahren zur Herstellung von neuen Isoxazolyläthyl-tetrahydropyranolen
AT314542B (de) Verfahren zur herstellung von 2,3-dihydrobenzodiazepinen
AT299946B (de) Verfahren zur Herstellung von neuen 1,3-Benzodioxol-2-thionen
AT306252B (de) Verfahren zur Herstellung von neuen 2,3-Alkylidenrhamnopyranosiden
AT309708B (de) Verfahren zur Herstellung des neuen 1,2α-Methylen-6,7α-difluormethylen-20-spirox-4-en-3-on
AT300206B (de) Verfahren zur Herstellung von neuen 6,7-Benzomorphanen
AT302547B (de) Verfahren zur Herstellung von neuen 3β-Alkoxymethoxy-14-hydroxy-5β-card-20(22)-enoliden
AT314100B (de) Verfahren zur Herstellung von neuen 16-Methylen-9β,10α-steroidverbindungen
AT315149B (de) Verfahren zur Herstellung von neuen ω-Alkenylpropiolophenonen

Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee