AT312174B - Verfahren zur Herstellung von neuen 16-Methylen-9β,10α-steroidverbindungen - Google Patents

Verfahren zur Herstellung von neuen 16-Methylen-9β,10α-steroidverbindungen

Info

Publication number
AT312174B
AT312174B AT171671A AT171671A AT312174B AT 312174 B AT312174 B AT 312174B AT 171671 A AT171671 A AT 171671A AT 171671 A AT171671 A AT 171671A AT 312174 B AT312174 B AT 312174B
Authority
AT
Austria
Prior art keywords
methylene
preparation
new
steroid compounds
steroid
Prior art date
Application number
AT171671A
Other languages
English (en)
Original Assignee
Philips Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philips Nv filed Critical Philips Nv
Priority to AT286873A priority Critical patent/ATA286873A/de
Application granted granted Critical
Publication of AT312174B publication Critical patent/AT312174B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0084Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkylene group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J53/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002Carbocyclic rings fused
    • C07J53/0043 membered carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/001Oxiranes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT171671A 1970-03-04 1971-03-01 Verfahren zur Herstellung von neuen 16-Methylen-9β,10α-steroidverbindungen AT312174B (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT286873A ATA286873A (de) 1970-03-04 1973-04-02 Verfahren zur herstellung von neuen 16-methylen-9beta,10alpha-steroiden

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7003061A NL7003061A (de) 1970-03-04 1970-03-04

Publications (1)

Publication Number Publication Date
AT312174B true AT312174B (de) 1973-12-27

Family

ID=19809487

Family Applications (9)

Application Number Title Priority Date Filing Date
AT914872A AT314100B (de) 1970-03-04 1971-03-01 Verfahren zur Herstellung von neuen 16-Methylen-9β,10α-steroidverbindungen
AT00697/72A AT313498B (de) 1970-03-04 1971-03-01 Verfahren zur herstellung von neuen 16-methylen-9beta,10 alpha-steroiden
AT171671A AT312174B (de) 1970-03-04 1971-03-01 Verfahren zur Herstellung von neuen 16-Methylen-9β,10α-steroidverbindungen
AT00692/72A AT313494B (de) 1970-03-04 1971-03-01 Verfahren zur herstellung von neuen 16-methylen-9beta,10 alpha-steroiden
AT00696/72A AT313497B (de) 1970-03-04 1971-03-01 Verfahren zur herstellung von neuen 16-methylen-9beta,10 alpha-steroiden
AT00695/72A AT313496B (de) 1970-03-04 1971-03-01 Verfahren zur herstellung von neuen 16-methylen-9beta,10 alpha-steroiden
AT00691/72A AT313493B (de) 1970-03-04 1971-03-01 Verfahren zur herstellung von neuen 16-methylen-9beta,10 alpha-steroiden
AT00694/72A AT314748B (de) 1970-03-04 1971-03-01 Verfahren zur herstellung von neuen 16-methylen-9beta-10alpha-steroiden
AT00693/72A AT313495B (de) 1970-03-04 1971-03-01 Verfahren zur herstellung von neuen 16-methylen-9beta,10 alpha-steroiden

Family Applications Before (2)

Application Number Title Priority Date Filing Date
AT914872A AT314100B (de) 1970-03-04 1971-03-01 Verfahren zur Herstellung von neuen 16-Methylen-9β,10α-steroidverbindungen
AT00697/72A AT313498B (de) 1970-03-04 1971-03-01 Verfahren zur herstellung von neuen 16-methylen-9beta,10 alpha-steroiden

Family Applications After (6)

Application Number Title Priority Date Filing Date
AT00692/72A AT313494B (de) 1970-03-04 1971-03-01 Verfahren zur herstellung von neuen 16-methylen-9beta,10 alpha-steroiden
AT00696/72A AT313497B (de) 1970-03-04 1971-03-01 Verfahren zur herstellung von neuen 16-methylen-9beta,10 alpha-steroiden
AT00695/72A AT313496B (de) 1970-03-04 1971-03-01 Verfahren zur herstellung von neuen 16-methylen-9beta,10 alpha-steroiden
AT00691/72A AT313493B (de) 1970-03-04 1971-03-01 Verfahren zur herstellung von neuen 16-methylen-9beta,10 alpha-steroiden
AT00694/72A AT314748B (de) 1970-03-04 1971-03-01 Verfahren zur herstellung von neuen 16-methylen-9beta-10alpha-steroiden
AT00693/72A AT313495B (de) 1970-03-04 1971-03-01 Verfahren zur herstellung von neuen 16-methylen-9beta,10 alpha-steroiden

Country Status (14)

Country Link
US (1) US3759960A (de)
JP (8) JPS5037664B1 (de)
AR (5) AR192737A1 (de)
AT (9) AT314100B (de)
BE (1) BE763753A (de)
CA (1) CA945544A (de)
DE (1) DE2109348A1 (de)
ES (1) ES388852A1 (de)
FR (1) FR2085670B1 (de)
GB (1) GB1336763A (de)
IL (1) IL36323A (de)
NL (1) NL7003061A (de)
SE (1) SE373748B (de)
ZA (1) ZA711290B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59139398A (ja) * 1983-01-12 1984-08-10 Daikin Ind Ltd 含フッ素ステロイド化合物の製法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3198792A (en) * 1962-06-12 1965-08-03 Philips Corp 10alpha methyl, 9beta hormonal steroids
DE1277253B (de) * 1963-01-19 1968-09-12 Merck Ag E Ungesaettigte 16-Methylen-17ª‡-alkoxy-3, 20-diketo-steroide der Pregnanreihe sowie ein Verfahren zu ihrer Herstellung
US3493588A (en) * 1968-03-25 1970-02-03 Schering Corp Process for the preparation of 6-chloro-16-methylene - 17alpha - lower alkanoyloxy-4,6-pregnadiene-3,20-dione and novel intermediates produced thereby

Also Published As

Publication number Publication date
AT313498B (de) 1974-01-15
JPS50105655A (de) 1975-08-20
AR192742A1 (es) 1973-03-14
NL7003061A (de) 1971-09-07
AT313497B (de) 1974-01-15
US3759960A (en) 1973-09-18
GB1336763A (en) 1973-11-07
FR2085670B1 (de) 1974-08-02
JPS50105654A (de) 1975-08-20
IL36323A (en) 1975-02-10
BE763753A (fr) 1971-09-03
AR192741A1 (es) 1973-03-14
CA945544A (en) 1974-04-16
AT314100B (de) 1974-03-25
AT313496B (de) 1974-01-15
AR192737A1 (es) 1973-03-14
DE2109348A1 (de) 1971-09-16
JPS50105653A (de) 1975-08-20
AT313495B (de) 1974-01-15
JPS50105659A (de) 1975-08-20
ES388852A1 (es) 1973-06-01
AT313494B (de) 1974-01-15
JPS5037664B1 (de) 1975-12-04
ZA711290B (en) 1972-10-25
JPS50105652A (de) 1975-08-20
SE373748B (de) 1975-02-17
IL36323A0 (en) 1971-05-26
JPS50142557A (de) 1975-11-17
JPS50105651A (de) 1975-08-20
AT314748B (de) 1974-03-15
AT313493B (de) 1974-01-15
AR192739A1 (es) 1973-03-14
FR2085670A1 (de) 1971-12-31
AR192740A1 (es) 1973-03-14

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