AT311984B - Verfahren zur Herstellung von neuen racemischen oder optisch aktiven Piperazinderivaten und deren Säureaddtionssalzen - Google Patents

Verfahren zur Herstellung von neuen racemischen oder optisch aktiven Piperazinderivaten und deren Säureaddtionssalzen

Info

Publication number
AT311984B
AT311984B AT1100072A AT1100072A AT311984B AT 311984 B AT311984 B AT 311984B AT 1100072 A AT1100072 A AT 1100072A AT 1100072 A AT1100072 A AT 1100072A AT 311984 B AT311984 B AT 311984B
Authority
AT
Austria
Prior art keywords
preparation
acid addition
addition salts
optically active
piperazine derivatives
Prior art date
Application number
AT1100072A
Other languages
English (en)
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Application granted granted Critical
Publication of AT311984B publication Critical patent/AT311984B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/56Radicals substituted by sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58Radicals substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/101,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/141,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/161,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/18Ethylenedioxybenzenes, not substituted on the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT1100072A 1970-07-30 1971-07-29 Verfahren zur Herstellung von neuen racemischen oder optisch aktiven Piperazinderivaten und deren Säureaddtionssalzen AT311984B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2037852A DE2037852C3 (de) 1970-07-30 1970-07-30 Neue Piperazinderivate und Verfahren zu ihrer Herstellung

Publications (1)

Publication Number Publication Date
AT311984B true AT311984B (de) 1973-12-10

Family

ID=5778382

Family Applications (6)

Application Number Title Priority Date Filing Date
AT1100172A AT311985B (de) 1970-07-30 1971-07-29 Verfahren zur Herstellung von neuen racemischen oder optisch aktiven Piperazinderivaten und deren Säureaddtionssalzen
AT664271A AT311976B (de) 1970-07-30 1971-07-29 Verfahren zur Herstellung von neuen racemischen oder optisch aktiven Piperazinderivaten und deren Säureadditionssalzen
AT1100372A AT311987B (de) 1970-07-30 1971-07-29 Verfahren zur Herstellung von neuen racemischen oder optisch aktiven Piperazinderivaten und deren Säureadditonssalzen
AT1100272A AT311986B (de) 1970-07-30 1971-07-29 Verfahren zur Herstellung von neuen racemischen oder optisch aktiven Piperazinderivaten und deren Säureadditionssalzen
AT1100472A AT311988B (de) 1970-07-30 1971-07-29 Verfahren zur Herstellung von neuen racemischen oder optisch aktiven Piperazinderivaten und deren Säureaddtionssalzen
AT1100072A AT311984B (de) 1970-07-30 1971-07-29 Verfahren zur Herstellung von neuen racemischen oder optisch aktiven Piperazinderivaten und deren Säureaddtionssalzen

Family Applications Before (5)

Application Number Title Priority Date Filing Date
AT1100172A AT311985B (de) 1970-07-30 1971-07-29 Verfahren zur Herstellung von neuen racemischen oder optisch aktiven Piperazinderivaten und deren Säureaddtionssalzen
AT664271A AT311976B (de) 1970-07-30 1971-07-29 Verfahren zur Herstellung von neuen racemischen oder optisch aktiven Piperazinderivaten und deren Säureadditionssalzen
AT1100372A AT311987B (de) 1970-07-30 1971-07-29 Verfahren zur Herstellung von neuen racemischen oder optisch aktiven Piperazinderivaten und deren Säureadditonssalzen
AT1100272A AT311986B (de) 1970-07-30 1971-07-29 Verfahren zur Herstellung von neuen racemischen oder optisch aktiven Piperazinderivaten und deren Säureadditionssalzen
AT1100472A AT311988B (de) 1970-07-30 1971-07-29 Verfahren zur Herstellung von neuen racemischen oder optisch aktiven Piperazinderivaten und deren Säureaddtionssalzen

Country Status (19)

Country Link
US (1) US3808212A (de)
JP (1) JPS5716989B1 (de)
AT (6) AT311985B (de)
AU (1) AU463957B2 (de)
BE (1) BE770800A (de)
BG (5) BG20369A3 (de)
CH (6) CH565167A5 (de)
CS (1) CS172929B2 (de)
DE (1) DE2037852C3 (de)
DK (1) DK137990C (de)
ES (6) ES393738A1 (de)
FR (1) FR2100972B1 (de)
GB (1) GB1344720A (de)
NL (1) NL173643C (de)
PL (6) PL84348B1 (de)
RO (6) RO60596A (de)
SE (2) SE375308B (de)
SU (5) SU437293A3 (de)
YU (7) YU34530B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3940396A (en) * 1973-02-28 1976-02-24 Uniroyal Inc. 1,2,3,4,4A,5,7,7A-Octahydrothieno[3,4-b]pyrazines 6,6-dioxides
US3991036A (en) * 1973-02-28 1976-11-09 Uniroyal Inc. Preparation of polyurethane using 1,2,3,4,4a,5,7,7a-Octahydrothieno[3,4-b]py
GB1407552A (en) * 1973-04-02 1975-09-24 Science Union & Cie Disubstituted piperazines processes for their preparation and pharmaceutical compositions containing them
GB1432660A (en) * 1973-10-30 1976-04-22 Science Union & Cie Piperazine derivatives processes for their preparation and and pharamacueitcal compositions containing them
US3960863A (en) * 1974-06-25 1976-06-01 Sankyo Company Limited Pyrido[1,2-a]pyrimidinone derivatives
DE2604838A1 (de) * 1976-02-07 1977-08-11 Knoll Ag Alkylendioxypiperazinderivate
EP0132267B1 (de) * 1983-01-21 1989-01-18 FISONS plc Aromatische amine
DE3571436D1 (en) * 1984-12-21 1989-08-17 Duphar Int Res New pharmaceutical compositions having anti-psychotic properties
FR2692264B1 (fr) * 1992-06-12 1994-08-05 Adir Nouvelles piperazines 1,4-disubstituees, leur procede de preparation et les compositions pharmaceutiques les contenant.
FR2734819B1 (fr) * 1995-05-31 1997-07-04 Adir Nouveaux composes de la piperazine, de la piperidine et de la 1,2,5,6-tetrahydropyridine, leur procede de preparation et les compositions pharmaceutiques les contenant
US6002005A (en) * 1995-06-02 1999-12-14 Neurogen Corporation Certain 1-substituted aminomethyl imidazole and pyrrole derivatives: novel dopamine receptor subtype specific ligands
FR2737724B1 (fr) * 1995-08-09 1997-09-05 Synthelabo Derives de 1-[2-(2,3-dihydro-1h-inden-1-yl)ethyl]-4- (naphtalen-1-yl) piperazine, leur preparation et leur application en therapeutique
JPH09124643A (ja) * 1995-08-14 1997-05-13 Bristol Myers Squibb Co 抗うつ作用を有する1−アリールアルキル−4−(アルコキシピリジニル)−又は4−(アルコキシピリミジニル)ピペラジン誘導体
US6040448A (en) * 1997-10-24 2000-03-21 Neurogen Corporation Certain 1-(2-naphthyl) and 1-(2-azanaphthyl)-4-(1-phenylmethyl) piperazines, dopamine receptor subtype specific ligands
MA41169A (fr) * 2014-12-17 2017-10-24 Acraf Composés antibactériens à large spectre d'activité

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL132357C (de) * 1966-09-03

Also Published As

Publication number Publication date
YU34891B (en) 1980-04-30
FR2100972A1 (de) 1972-03-24
SE7408533L (de) 1974-06-27
YU34890B (en) 1980-04-30
YU59778A (en) 1980-04-30
CH565165A5 (de) 1975-08-15
AU463957B2 (en) 1975-08-14
ES396212A1 (es) 1974-04-16
US3808212A (en) 1974-04-30
SU437290A3 (ru) 1974-07-25
FR2100972B1 (de) 1974-11-15
CS172929B2 (de) 1977-01-28
SU416945A3 (ru) 1974-02-25
SU437289A3 (ru) 1974-07-25
AT311987B (de) 1973-12-10
SE403288B (sv) 1978-08-07
DE2037852B2 (de) 1979-10-11
RO60596A (de) 1976-08-15
ES396213A1 (es) 1974-04-16
YU59878A (en) 1979-10-31
DE2037852A1 (de) 1972-02-03
DK137990B (da) 1978-06-19
BE770800A (fr) 1972-01-31
AT311988B (de) 1973-12-10
BG20594A3 (de) 1975-12-05
ES396214A1 (es) 1974-04-16
SU437291A3 (ru) 1974-07-25
AU3177271A (en) 1973-02-01
AT311976B (de) 1973-12-10
DK137990C (da) 1978-11-13
AT311985B (de) 1973-12-10
NL173643B (nl) 1983-09-16
YU34888B (en) 1980-04-30
SU437293A3 (ru) 1974-07-25
PL91965B1 (de) 1977-03-31
YU59978A (en) 1979-10-31
YU198671A (en) 1979-02-28
ES396215A1 (es) 1974-04-16
ES396216A1 (es) 1974-04-16
YU34530B (en) 1979-09-10
CH575412A5 (de) 1976-05-14
AT311986B (de) 1973-12-10
BG20369A3 (bg) 1975-11-05
CH565166A5 (de) 1975-08-15
SE375308B (de) 1975-04-14
YU35248B (en) 1980-10-31
NL7110538A (de) 1972-02-01
RO60599A (de) 1976-08-15
BG21029A3 (bg) 1976-01-20
DE2037852C3 (de) 1980-06-26
YU34889B (en) 1980-04-30
BG20370A3 (bg) 1975-11-05
RO60598A (de) 1976-07-15
RO61040A (de) 1976-08-15
RO60597A (de) 1976-08-15
YU138878A (en) 1982-10-31
SU440840A3 (de) 1974-08-25
CH565780A5 (de) 1975-08-29
YU59678A (en) 1979-10-31
ES393738A1 (es) 1974-07-01
SU437292A3 (ru) 1974-07-25
RO59997A (de) 1976-06-15
YU60078A (en) 1979-10-31
BG19598A3 (de) 1975-06-25
PL84348B1 (de) 1976-03-31
PL84664B1 (de) 1976-04-30
PL84349B1 (de) 1976-03-31
CH565167A5 (de) 1975-08-15
GB1344720A (en) 1974-01-23
JPS5716989B1 (de) 1982-04-08
PL84610B1 (de) 1976-04-30
PL84347B1 (de) 1976-03-31
CH565781A5 (de) 1975-08-29
NL173643C (nl) 1984-02-16

Similar Documents

Publication Publication Date Title
ATA266376A (de) Verfahren zur herstellung von neuen substituierten 3-aminoalkylamino-2-hydroxy-1-phenoxypropanen und von deren saureadditionssalzen
AT343639B (de) Verfahren zur herstellung von neuen racemischen oder optisch aktiven 3,4-dihydroxyphenyl-alfa-methylalaninestern und deren saureadditionssalzen
AT298459B (de) Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-Phenoxy-2-hydroxy-3-alkylaminopropanen und von deren Säureadditionssalzen
AT311985B (de) Verfahren zur Herstellung von neuen racemischen oder optisch aktiven Piperazinderivaten und deren Säureaddtionssalzen
AT296256B (de) Verfahren zur Herstellung von neuen racemischen oder optisch aktiven substituierten 3-Carbamoylphenoxy-2-hydroxy-aminopropanen und von deren Säureadditionssalzen
AT321276B (de) Verfahren zur Herstellung von neuen substituierten 3-Phenoxy-aminopropan-2-olen und deren Säureadditionssalzen
AT318600B (de) Verfahren zur Herstellung von neuen, racemischen oder optisch aktiven N-(Furyl-methyl)-morphinanen und deren Säureadditionssalzen
AT280307B (de) Verfahren zur Herstellung von neuen racemischen oder optisch aktiven Piperazinderivaten sowie von deren Säureadditionssalzen
AT299970B (de) Verfahren zur Herstellung von neuen Morpholin- und Piperazinderivaten und von deren Säureadditionssalzen
AT325018B (de) Verfahren zur herstellung von neuen 1-(trifluormethoxy- oder trifluormethylthiophenyl)-2-aminopropanen und deren säureadditionssalzen
AT308123B (de) Verfahren zur Herstellung von neuen Thienobenzothiazepinderivaten und von deren Säureadditionssalzen
AT321265B (de) Verfahren zur Herstellung von neuen Benzobicycloalkanaminen und deren Säureadditionssalzen
AT310156B (de) Verfahren zur Herstellung von neuen Thienyl-imidazolyl-fettsäurederivaten und deren Salzen
AT287727B (de) Verfahren zur Herstellung von neuen Piperazinderivaten und von deren Saureadditionssalze
AT320611B (de) Verfahren zur Herstellung von neuen substituierten Phenylformamidinen und deren Säureadditionssalzen
AT310142B (de) Verfahren zur Herstellung von neuen 1-Acylaminoalkylphenoxy-2- -hydroxy-3-alkylaminopropanen und von deren Säureadditionssalzen
AT305250B (de) Verfahren zur Herstellung von neuen 1-Hydroxyphenyl-1-hydroxy-2-(3-aryl-3-hydroxypropyl)-aminoäthanen und von deren Säureadditionssalzen
AT335417B (de) Verfahren zur herstellung von neuen substituierten 2- (alfa-aminobenzyl) -cycloalkanolen und deren saureadditionssalzen und n-oxyden
AT317234B (de) Verfahren zur Herstellung von neuen Phenothiazinderivaten und von deren Säureadditionssalzen
AT318556B (de) Verfahren zur Herstellung von neuen 2-Aminobornanen und von deren Säureadditionssalzen
AT308072B (de) Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-(2'-Cyano-5'-methylphenoxy)-2-hydroxy-3-alkylaminopropanen und von deren Säureadditionssalzen
AT306730B (de) Verfahren zur Herstellung von neuen Piperazinderivaten und von deren Säureadditionssalzen
AT308720B (de) Verfahren zur Herstellung von neuen substituierten N-Phenylthioalkyl-phenylalkanolaminen und von deren Säureadditionssalzen
AT310183B (de) Verfahren zur Herstellung von neuen Pyridazinderivaten und von deren Säureadditionssalzen
AT313902B (de) Verfahren zur Herstellung von Piperazinderivaten sowie von deren Säureadditionssalzen

Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee