AT176303B - Verfahren zur Darstellung von Morphinanabkömmlingen und ihren Salzen - Google Patents

Verfahren zur Darstellung von Morphinanabkömmlingen und ihren Salzen

Info

Publication number
AT176303B
AT176303B AT176303DA AT176303B AT 176303 B AT176303 B AT 176303B AT 176303D A AT176303D A AT 176303DA AT 176303 B AT176303 B AT 176303B
Authority
AT
Austria
Prior art keywords
salts
preparation
morphine derivatives
morphine
derivatives
Prior art date
Application number
Other languages
English (en)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of AT176303B publication Critical patent/AT176303B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/04Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/10Quaternary compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18Aralkyl radicals
    • C07D217/20Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22Bridged ring systems
    • C07D221/28Morphinans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT176303D 1949-07-29 1950-05-09 Verfahren zur Darstellung von Morphinanabkömmlingen und ihren Salzen AT176303B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH4731549 1949-07-29

Publications (1)

Publication Number Publication Date
AT176303B true AT176303B (de) 1953-10-10

Family

ID=38464500

Family Applications (1)

Application Number Title Priority Date Filing Date
AT176303D AT176303B (de) 1949-07-29 1950-05-09 Verfahren zur Darstellung von Morphinanabkömmlingen und ihren Salzen

Country Status (7)

Country Link
US (1) US2634273A (de)
AT (1) AT176303B (de)
CH (5) CH301668A (de)
DE (1) DE899354C (de)
DK (1) DK81182C (de)
ES (1) ES193818A1 (de)
FR (1) FR1022383A (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2714107A (en) * 1955-07-26 Racemisation procedure for i-
DE1014545B (de) * 1953-11-12 1957-08-29 Hoffmann La Roche Verfahren zur Herstellung von N-Alkyl-, N-Alkenyl- oder N-Aralkyl-3-oxymorphinanen
DE1109688B (de) * 1957-10-22 1961-06-29 Berlin Chemie Veb Verfahren zur Herstellung von 1-(p-Methoxybenzyl)-10-hydroxy-dekahydroisochinolin
US4496762A (en) * 1983-03-29 1985-01-29 Eastman Kodak Company Process for the preparation of N-(2-(cyclo-hexen-1-yl)ethyl)-4-methoxybenzeneacetamide
CN102241630A (zh) * 2011-05-20 2011-11-16 杭州保灵集团有限公司 一种镇咳嗽药磷酸二甲啡烷的制备方法
CN104761495A (zh) * 2014-01-08 2015-07-08 上海医药工业研究院 一种新化合物及其制备方法和用途
MX2018011877A (es) * 2016-03-29 2019-03-06 Hikal Ltd Proceso mejorado para la preparacion de tartrato de butorfanol.
CN105859566A (zh) * 2016-04-12 2016-08-17 叶芳 一种环己烯乙胺及其制备方法
CN106632041B (zh) * 2016-10-11 2019-07-12 安徽省逸欣铭医药科技有限公司 一种酒石酸左洛啡烷的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB620258A (en) * 1947-01-13 1949-03-22 Hoffmann La Roche Improvements in or relating to the manufacture of hydro-phenanthrene derivatives

Also Published As

Publication number Publication date
CH280674A (de) 1952-01-31
US2634273A (en) 1953-04-07
ES193818A1 (es) 1951-09-16
CH301670A (de) 1954-09-15
CH301668A (de) 1954-09-15
DE899354C (de) 1953-12-10
CH301669A (de) 1954-09-15
DK81182C (da) 1956-10-15
CH301667A (de) 1954-09-15
FR1022383A (fr) 1953-03-04

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