AR195350A1 - Un procedimiento para preparar tri-p-toluensulfonato de s-adenosil-l-metionina - Google Patents

Un procedimiento para preparar tri-p-toluensulfonato de s-adenosil-l-metionina

Info

Publication number
AR195350A1
AR195350A1 AR249310A AR24931073A AR195350A1 AR 195350 A1 AR195350 A1 AR 195350A1 AR 249310 A AR249310 A AR 249310A AR 24931073 A AR24931073 A AR 24931073A AR 195350 A1 AR195350 A1 AR 195350A1
Authority
AR
Argentina
Prior art keywords
toluensulphonate
adenosyl
methionine
tri
preparing
Prior art date
Application number
AR249310A
Other languages
English (en)
Spanish (es)
Original Assignee
Errekappa Euroterapici Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Errekappa Euroterapici Sas filed Critical Errekappa Euroterapici Sas
Application granted granted Critical
Publication of AR195350A1 publication Critical patent/AR195350A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • C12P19/28N-glycosides
    • C12P19/38Nucleosides
    • C12P19/40Nucleosides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same ring, e.g. purine nucleosides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Microbiology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • General Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
AR249310A 1972-08-02 1973-07-27 Un procedimiento para preparar tri-p-toluensulfonato de s-adenosil-l-metionina AR195350A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2779372 1972-08-02

Publications (1)

Publication Number Publication Date
AR195350A1 true AR195350A1 (es) 1973-09-28

Family

ID=11222342

Family Applications (1)

Application Number Title Priority Date Filing Date
AR249310A AR195350A1 (es) 1972-08-02 1973-07-27 Un procedimiento para preparar tri-p-toluensulfonato de s-adenosil-l-metionina

Country Status (29)

Country Link
US (1) US3893999A (xx)
JP (1) JPS5235726B2 (xx)
AR (1) AR195350A1 (xx)
AT (1) AT341684B (xx)
AU (1) AU474015B2 (xx)
BE (1) BE802981A (xx)
CA (1) CA1006872A (xx)
CH (1) CH592112A5 (xx)
CS (1) CS195254B2 (xx)
DD (1) DD107461A5 (xx)
DE (1) DE2336401C3 (xx)
DK (1) DK131868C (xx)
ES (1) ES417377A1 (xx)
FI (1) FI52466C (xx)
FR (1) FR2194425B1 (xx)
GB (1) GB1425384A (xx)
HK (1) HK31580A (xx)
HU (1) HU167266B (xx)
IE (1) IE37913B1 (xx)
IL (1) IL42764A (xx)
MX (1) MX4544E (xx)
NL (1) NL152864B (xx)
NO (1) NO137941C (xx)
PL (1) PL87381B1 (xx)
RO (1) RO63451A (xx)
SE (1) SE400085B (xx)
SU (1) SU646915A3 (xx)
YU (1) YU36037B (xx)
ZA (1) ZA734876B (xx)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE39517B1 (en) * 1973-06-27 1978-10-25 Bioresearch Sas Double salts of s-adenosyl-l-methhionine
AR221676A1 (es) * 1974-07-12 1981-03-13 Bioresearch Sas Procedimiento para la preparacion de sales estables sulfonicas y/o sulfuricas de la s-adenosil-l-metionina,particularmente utiles como donadores especificos de metilo para las reacciones bioquimicas de transferencia del grupo ch3;asi como tambien las reacciones fundamentales en el metabolismo lipilico,protilico y glucidico
US4109079A (en) * 1975-10-16 1978-08-22 Yamasa Shoyu Kabushiki Kaisha Stabilized s-adenosyl-l-methionine preparations
GB2064523B (en) * 1979-12-04 1983-06-29 Kanegafuchi Chemical Ind Stable composition of s-adenosyl-l-methionine
IT1137640B (it) 1981-08-24 1986-09-10 Bioresearch Srl Sali stabili della s-adenosilmetionina,processo per la loro preparazione e composizioni terapeutiche che li comprendono come principio attivo
IT1137892B (it) * 1981-08-24 1986-09-10 Bioresearch Srl Sali stabili della s-adenosilmetionina,processo per la loro preparazione e composizioni terapeutiche che li comprendono come principio attivo
IT1139974B (it) * 1981-09-11 1986-09-24 Bioresearch Srl Derivati della s-adenosilmetionina,processo per la preparazione e composizioni terapeutiche che li contengono come principio attivo
IT1169773B (it) * 1983-08-24 1987-06-03 Bioresearch Spa Processo per la produzione di sali stabili della solfo-adenosil-l-metionina
IT1169774B (it) * 1983-08-24 1987-06-03 Bioresearch Spa Composizioni terapeutiche iniettabili contenenti sali stabili della s-adenosil-l-metionina
IT1173992B (it) * 1984-05-16 1987-06-24 Bioresearch Spa Sali stabili della solfo-adenosil-l-metionina (same) particolarmente idonei per uso farmaceutico orale
IT1173990B (it) * 1984-05-16 1987-06-24 Bioresearch Spa Sali stabili della solfo-adenosil-l-metionina (same) particolarmente adatti per uso parenterale
IT1200589B (it) * 1985-02-14 1989-01-27 Gibipharma Spa Derivati naturali attivita farmagologica
AU2538588A (en) * 1987-10-09 1989-05-02 Mario De Rosa Lipophilic salts of s-adenosyl-l-methionine (sam) with acylated taurine derivatives
DE19515275A1 (de) * 1995-04-26 1996-10-31 Knoll Ag Neue Verwendung von (S)-Adenosyl-L-methionin(SAMe)
US6759395B2 (en) 2000-12-18 2004-07-06 Orchid Chemicals & Pharmaceuticals, Ltd. Soft-gelatin capsule comprising S-adenosylmethionine and a method for producing the same
US8063024B2 (en) * 2005-01-26 2011-11-22 University Of Manitoba Use of S-adenosylmethionine, vitamin E, and vitamin C for the treatment of oxidative liver injury and insulin resistance
US20090012036A1 (en) * 2005-05-24 2009-01-08 Hebert Rolland F Stable S-adenosyl-L-methionine
ITMI20060629A1 (it) 2006-03-31 2007-10-01 Daniele Giovannone Composizioni solide orali a base di s-adenosilmetionina e processo per il loro ottenimento
CA2677053C (en) * 2007-01-31 2016-03-15 Methylation Sciences International Srl Extended release pharmaceutical formulations of s-adenosylmethionine
US20090088404A1 (en) * 2007-01-31 2009-04-02 Methylation Sciences International Srl Extended Release Pharmaceutical Formulations of S-Adenosylmethionine
US20090197824A1 (en) * 2008-01-31 2009-08-06 Methylation Sciences International Srl Extended Release Pharmaceutical Formulations of S-Adenosylmethionine
ITMI20071374A1 (it) * 2007-07-10 2009-01-11 Gnosis Spa Sali stabili di s-adenosilmetionina e processo per il loro ottenimento.
US20100004191A1 (en) * 2008-07-01 2010-01-07 Rolland F Hebert Compositions of S-adenosyl-L-methionine.
US8329208B2 (en) 2009-07-28 2012-12-11 Methylation Sciences International Srl Pharmacokinetics of S-adenosylmethionine formulations
US20110027342A1 (en) * 2009-07-28 2011-02-03 Msi Methylation Sciences, Inc. S-adenosylmethionine formulations with enhanced bioavailability
EP2696879A4 (en) 2011-04-15 2014-11-26 Scimar Ltd USE OF S-ADENOSYLMETHIONINE, VITAMIN E AND VITAMIN C IN THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DYSFUNCTION
CN106074589A (zh) 2012-10-17 2016-11-09 甲基化物科学国际有限公司 包含s‑腺苷甲硫氨酸及没食子酸酯的组合物
EP2945959B1 (en) 2013-01-16 2020-05-13 Hebert Sam-E LLC Stable indole-3-propionate salts of s-adenosyl-l-methionine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2946781A (en) * 1957-02-06 1960-07-26 Merck & Co Inc Process for the preparation of adenosyl homocysteine
US3642772A (en) * 1968-09-04 1972-02-15 Boehringer Mannheim Gmbh Process for preparing s-adenosyl homocysteine

Also Published As

Publication number Publication date
YU36037B (en) 1981-11-13
ES417377A1 (es) 1976-02-16
DK131868B (da) 1975-09-15
SU646915A3 (ru) 1979-02-05
AU474015B2 (en) 1976-07-08
CS195254B2 (en) 1980-01-31
HU167266B (xx) 1975-09-27
ATA664173A (de) 1977-06-15
CH592112A5 (xx) 1977-10-14
DE2336401C3 (de) 1980-03-13
NL7310706A (xx) 1974-02-05
FI52466B (xx) 1977-05-31
NO137941C (no) 1978-05-31
IE37913L (en) 1974-02-02
DD107461A5 (xx) 1974-08-05
IE37913B1 (en) 1977-11-09
IL42764A (en) 1976-04-30
FR2194425B1 (xx) 1976-04-09
AU5868073A (en) 1975-01-30
CA1006872A (en) 1977-03-15
FI52466C (fi) 1977-09-12
SE400085B (sv) 1978-03-13
NO137941B (no) 1978-02-13
NL152864B (nl) 1977-04-15
ZA734876B (en) 1974-06-26
PL87381B1 (xx) 1976-06-30
DK131868C (da) 1976-03-08
HK31580A (en) 1980-06-20
YU203073A (en) 1981-04-30
RO63451A (fr) 1978-07-15
AT341684B (de) 1978-02-27
DE2336401A1 (de) 1974-02-14
US3893999A (en) 1975-07-08
JPS5235726B2 (xx) 1977-09-10
DE2336401B2 (de) 1979-07-12
MX4544E (es) 1982-06-08
IL42764A0 (en) 1974-01-14
GB1425384A (en) 1976-02-18
FR2194425A1 (xx) 1974-03-01
BE802981A (fr) 1973-11-16
JPS4992215A (xx) 1974-09-03

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