AR122575A2 - Una composición farmacéutica en forma de torta liofilizada que comprende aripiprazol como ingrediente activo y métodos para producir un dispositivo médico y la composición - Google Patents
Una composición farmacéutica en forma de torta liofilizada que comprende aripiprazol como ingrediente activo y métodos para producir un dispositivo médico y la composiciónInfo
- Publication number
- AR122575A2 AR122575A2 ARP210101568A ARP210101568A AR122575A2 AR 122575 A2 AR122575 A2 AR 122575A2 AR P210101568 A ARP210101568 A AR P210101568A AR P210101568 A ARP210101568 A AR P210101568A AR 122575 A2 AR122575 A2 AR 122575A2
- Authority
- AR
- Argentina
- Prior art keywords
- composition
- aripiprazole
- cake
- active ingredient
- pharmaceutical composition
- Prior art date
Links
- CEUORZQYGODEFX-UHFFFAOYSA-N Aripirazole Chemical compound ClC1=CC=CC(N2CCN(CCCCOC=3C=C4NC(=O)CCC4=CC=3)CC2)=C1Cl CEUORZQYGODEFX-UHFFFAOYSA-N 0.000 title abstract 10
- 229960004372 aripiprazole Drugs 0.000 title abstract 10
- 239000000203 mixture Substances 0.000 title abstract 9
- 239000004480 active ingredient Substances 0.000 title abstract 8
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 3
- 238000003860 storage Methods 0.000 abstract 3
- 229920001296 polysiloxane Polymers 0.000 abstract 2
- 239000000725 suspension Substances 0.000 abstract 2
- 238000005054 agglomeration Methods 0.000 abstract 1
- 230000002776 aggregation Effects 0.000 abstract 1
- 238000004108 freeze drying Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/19—Syringes having more than one chamber, e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
- A61M5/284—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle comprising means for injection of two or more media, e.g. by mixing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04C—ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT PUMPS
- F04C2270/00—Control; Monitoring or safety arrangements
- F04C2270/04—Force
- F04C2270/042—Force radial
- F04C2270/0421—Controlled or regulated
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Mechanical Engineering (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Dispersion Chemistry (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
La presente invención provee un dispositivo médico que contiene una composición en forma de torta que comprende aripiprazol como ingrediente activo y que es capaz de suprimir la aglomeración de aripiprazol en una suspensión obtenida por la resuspensión de una sustancia liofilizada; y una composición en forma de torta que comprende aripiprazol como ingrediente activo. La presente invención se refiere a un dispositivo médico que contiene, en un recipiente de almacenamiento cuya pared interna es tratada con silicona, una composición en forma de torta liofilizada que comprende aripiprazol preparado por separado como ingrediente activo, donde hay un espacio libre entre la pared interna y la composición en forma de torta; y una composición en forma de torta liofilizada que comprende aripiprazol como ingrediente activo y que presenta una fuerza de 5 a 100 N. Reivindicación 1: Una composición farmacéutica en forma de torta liofilizada, caracterizada porque comprende aripiprazol como ingrediente activo y que presenta una fuerza de 5 a 100 N, donde la composición farmacéutica en forma de torta liofilizada presenta una forma cilíndrica; y una superficie lateral de la composición farmacéutica en forma de torta liofilizada cilíndrica presenta una inclinación. Reivindicación 4: La composición farmacéutica en forma de torta liofilizada de acuerdo con una cualquiera de las reivindicaciones 1 a 3, caracterizada porque es obtenida por liofilización de 0,25 g a 12 g de una suspensión que tiene un contenido de sólidos de aripiprazol comprendido entre 5% y 45% en masa. Reivindicación 8: Un método para la producción de un dispositivo médico que contiene una composición en forma de torta que comprende aripiprazol como ingrediente activo, método caracterizado porque comprende: un paso de colocación de una composición en forma de torta liofilizada preparada por separado que comprende aripiprazol como ingrediente activo en un recipiente de almacenamiento cuya pared interna está tratada con silicona; en el cual hay un espacio libre entre la pared interna del recipiente de almacenamiento y la composición en forma de torta.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011011711 | 2011-01-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR122575A2 true AR122575A2 (es) | 2022-09-21 |
Family
ID=45592780
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP120100209A AR084914A1 (es) | 2011-01-24 | 2012-01-23 | Dispositivo medico que contiene una composicion en torta que comprende aripiprazol como ingrediente activo, y una composicion en torta que comprende aripiprazol como ingrediente activo, metodo |
| ARP210101568A AR122575A2 (es) | 2011-01-24 | 2021-06-09 | Una composición farmacéutica en forma de torta liofilizada que comprende aripiprazol como ingrediente activo y métodos para producir un dispositivo médico y la composición |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP120100209A AR084914A1 (es) | 2011-01-24 | 2012-01-23 | Dispositivo medico que contiene una composicion en torta que comprende aripiprazol como ingrediente activo, y una composicion en torta que comprende aripiprazol como ingrediente activo, metodo |
Country Status (29)
| Country | Link |
|---|---|
| US (2) | US11648347B2 (es) |
| EP (1) | EP2667856B9 (es) |
| JP (2) | JP5980215B2 (es) |
| KR (2) | KR101905215B1 (es) |
| CN (2) | CN103327968B (es) |
| AR (2) | AR084914A1 (es) |
| AU (1) | AU2012209853B2 (es) |
| BR (1) | BR112013018664B1 (es) |
| CA (2) | CA2910333C (es) |
| CO (1) | CO6751272A2 (es) |
| CY (1) | CY1124447T1 (es) |
| DK (1) | DK2667856T3 (es) |
| EA (1) | EA024814B1 (es) |
| ES (1) | ES2884825T3 (es) |
| HR (1) | HRP20211295T1 (es) |
| HU (1) | HUE055836T2 (es) |
| IL (1) | IL227364A (es) |
| JO (1) | JO3508B1 (es) |
| LT (1) | LT2667856T (es) |
| MX (1) | MX354319B (es) |
| MY (1) | MY163272A (es) |
| PL (1) | PL2667856T3 (es) |
| PT (1) | PT2667856T (es) |
| SG (2) | SG10201600202UA (es) |
| SI (1) | SI2667856T1 (es) |
| TW (1) | TWI594753B (es) |
| UA (1) | UA113727C2 (es) |
| WO (1) | WO2012102216A1 (es) |
| ZA (1) | ZA201305199B (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JOP20200109A1 (ar) | 2012-04-23 | 2017-06-16 | Otsuka Pharma Co Ltd | مستحضر قابل للحقن |
| EP3009354A1 (en) * | 2014-10-15 | 2016-04-20 | F. Hoffmann-La Roche AG | Method for providing in a primary packaging container a dried solid product containing an active pharmaceutical ingredient |
| US11219578B2 (en) | 2015-06-19 | 2022-01-11 | Takeda Pharmaceutical Company Limited | Pooling device for single or multiple medical containers |
| ITUA20164317A1 (it) * | 2016-06-13 | 2017-12-13 | Orofino Pharmaceuticals Group Srl | Dispositivo di iniezione pre-riempito a tripla camera |
| SG11202004467PA (en) * | 2017-11-17 | 2020-06-29 | Swedish Orphan Biovitrum Ab Publ | Syringe assembly with ion-exchange material |
| KR102382436B1 (ko) | 2018-07-20 | 2022-04-04 | 주식회사 엘지에너지솔루션 | 파우치형 이차전지의 제조방법 |
| CN113015510A (zh) | 2018-10-03 | 2021-06-22 | 武田药品工业株式会社 | 用于多个容器的封装 |
| CN114786724A (zh) | 2019-12-16 | 2022-07-22 | 尼普洛株式会社 | 防聚集剂以及使用该防聚集剂的药物组合物和医疗用设备 |
| CN115190835A (zh) * | 2020-03-09 | 2022-10-14 | 艾德克斯实验室公司 | 在将液体样品分配在化学试剂试验载玻片上之前从液体样品中除去干扰组分的方法 |
| GR1010624B (el) * | 2023-03-23 | 2024-01-30 | Φαρματεν Α.Β.Ε.Ε., | Φαρμακευτικο σκευασμα που περιλαμβανει αριπιπραζολη και μεθοδος για την παρασκευη αυτου |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58165852A (ja) | 1982-03-26 | 1983-09-30 | 小太郎漢方製薬株式会社 | 薬品、食品等の濃縮液を乾燥する方法及びその装置 |
| US5006528A (en) | 1988-10-31 | 1991-04-09 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
| JPH02225370A (ja) * | 1989-02-27 | 1990-09-07 | Mitsubishi Electric Corp | マイカ複合セラミックスの製法 |
| US5290228A (en) * | 1990-11-17 | 1994-03-01 | Santen Seiyaku Kabushiki Kaisha | Two-compartment syringe |
| JPH0626570B2 (ja) * | 1991-01-31 | 1994-04-13 | 参天製薬株式会社 | 二層式注射器の注射筒 |
| JP3121632B2 (ja) * | 1991-04-30 | 2001-01-09 | 株式会社アズウェル | 凍結乾燥製剤の製造方法及び凍結真空乾燥装置 |
| JP2767016B2 (ja) * | 1992-07-14 | 1998-06-18 | 株式会社大塚製薬工場 | 凍結乾燥用容器 |
| AR247101A1 (es) | 1993-03-10 | 1994-11-30 | Moreno Saul Szapiro Jaime Luis | Jeringa descartable de doble camara para la dilucion y administracion simultanea de drogas en polvo |
| JPH08112333A (ja) | 1994-10-12 | 1996-05-07 | Maeda Sangyo Kk | 用時溶解型プレフィルドシリンジの凍結乾燥製剤充填方法 |
| DE4445969C1 (de) | 1994-12-22 | 1996-03-14 | Schott Glaswerke | Spritzenzylinder für eine Zweikammer-Fertigspritze, Zweikammer-Fertigspritze und Verfahren zum Herstellen und Füllen derselben |
| US5876372A (en) | 1995-03-22 | 1999-03-02 | Abbott Laboratories | Syringe system accomodating seperate prefilled barrels for two constituents |
| US5607400A (en) | 1995-05-19 | 1997-03-04 | Becton, Dickinson And Company | Pre-fillable syringe and stopper assembly therefor |
| JP3654685B2 (ja) * | 1995-05-26 | 2005-06-02 | 株式会社ミューチュアル | 薬液の凍結乾燥方法及び凍結乾燥薬剤の充填包装方法 |
| US5971953A (en) * | 1998-01-09 | 1999-10-26 | Bachynsky; Nicholas | Dual chamber syringe apparatus |
| JPH11155951A (ja) | 1997-12-01 | 1999-06-15 | Kaken Pharmaceut Co Ltd | 減圧シリンジおよびその製造方法 |
| US6200627B1 (en) | 1998-03-17 | 2001-03-13 | Becton, Dickinson And Company | Low silicone glass prefillable syringe |
| US6093175A (en) | 1998-06-05 | 2000-07-25 | Becton Dickinson And Company | Localized lubrication of syringe barrels and stoppers |
| US6149628A (en) | 1998-07-20 | 2000-11-21 | Szapiro; Jaime Luis | Syringe with two variable volume chambers for containing and administering mixtures of products provided separately |
| ATE308354T1 (de) * | 1999-04-16 | 2005-11-15 | Becton Dickinson Co | Stiftförmiger injektor mit merkmalen zur automatischen substanzkombination |
| FR2799654B1 (fr) * | 1999-10-13 | 2002-01-11 | Sod Conseils Rech Applic | Dispositif pour reconstituer une solution, une suspension ou une dispersion therapeutique et procede de preparation et de conditionnement dans ce dispositif |
| US7621887B2 (en) * | 2000-10-10 | 2009-11-24 | Meridian Medical Technologies, Inc. | Wet/dry automatic injector assembly |
| US7021561B2 (en) * | 2001-12-18 | 2006-04-04 | Becton, Dickinson And Company | Spray device and method |
| WO2004064901A2 (en) | 2003-01-20 | 2004-08-05 | Jarto Holding Aps | Syringe to be pre-filled and for long-term storage of medicament |
| TWI371274B (en) | 2003-10-23 | 2012-09-01 | Bristol Myers Squibb Co | Process for making sterile aripiprazole of desired mean particle size |
| JP4836797B2 (ja) * | 2003-10-23 | 2011-12-14 | 大塚製薬株式会社 | 放出制御性無菌注射アリピプラゾール製剤および方法 |
| JP2005200409A (ja) | 2003-12-17 | 2005-07-28 | Takeda Chem Ind Ltd | 注射剤 |
| TW200526268A (en) | 2003-12-17 | 2005-08-16 | Takeda Pharmaceutical | Injectable composition |
| JP2005306216A (ja) | 2004-04-21 | 2005-11-04 | Nsk Ltd | 車両用ステアリングシステム |
| JP2009508859A (ja) | 2005-09-15 | 2009-03-05 | エラン ファーマ インターナショナル リミテッド | ナノ粒子アリピプラゾール製剤 |
| JP4373983B2 (ja) | 2006-01-27 | 2009-11-25 | 三菱電機インフォメーションシステムズ株式会社 | 流通経路管理装置及び流通経路管理プログラム |
| DK2170279T3 (en) * | 2007-07-31 | 2018-03-12 | Otsuka Pharma Co Ltd | PROCEDURES FOR PREPARING AN ARIPIPRAZOL SUSPENSION AND A FREEZER DRIED FORMULATION |
| DE102008030268B3 (de) | 2008-06-19 | 2010-02-04 | Arzneimittel Gmbh Apotheker Vetter & Co. Ravensburg | Verfahren zum Befüllen von Doppelkammersystemen in vorsterilisierbaren Trägersystemen und vorsterilisierbares Trägersystem |
| JP2010025370A (ja) | 2008-07-15 | 2010-02-04 | Hosokawa Yoko Co Ltd | 凍結乾燥容器および凍結乾燥物の製造方法 |
| JP4536825B1 (ja) | 2010-02-05 | 2010-09-01 | 株式会社アルテ | 二室式容器兼用注射器の製造方法及び製剤入りスリーブ |
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2012
- 2012-01-17 JP JP2013531814A patent/JP5980215B2/ja active Active
- 2012-01-17 CN CN201280006271.7A patent/CN103327968B/zh active Active
- 2012-01-17 SG SG10201600202UA patent/SG10201600202UA/en unknown
- 2012-01-17 CA CA2910333A patent/CA2910333C/en active Active
- 2012-01-17 PT PT127038982T patent/PT2667856T/pt unknown
- 2012-01-17 KR KR1020137022304A patent/KR101905215B1/ko active IP Right Grant
- 2012-01-17 SI SI201231937T patent/SI2667856T1/sl unknown
- 2012-01-17 EP EP12703898.2A patent/EP2667856B9/en active Active
- 2012-01-17 HU HUE12703898A patent/HUE055836T2/hu unknown
- 2012-01-17 WO PCT/JP2012/051285 patent/WO2012102216A1/en active Application Filing
- 2012-01-17 CA CA2824982A patent/CA2824982C/en active Active
- 2012-01-17 BR BR112013018664-0A patent/BR112013018664B1/pt active IP Right Grant
- 2012-01-17 PL PL12703898T patent/PL2667856T3/pl unknown
- 2012-01-17 MX MX2013008433A patent/MX354319B/es active IP Right Grant
- 2012-01-17 CN CN201510571923.7A patent/CN105125509B/zh active Active
- 2012-01-17 KR KR1020187020066A patent/KR101962085B1/ko active IP Right Grant
- 2012-01-17 LT LTEPPCT/JP2012/051285T patent/LT2667856T/lt unknown
- 2012-01-17 DK DK12703898.2T patent/DK2667856T3/da active
- 2012-01-17 US US13/981,229 patent/US11648347B2/en active Active
- 2012-01-17 UA UAA201310407A patent/UA113727C2/uk unknown
- 2012-01-17 EA EA201391078A patent/EA024814B1/ru not_active IP Right Cessation
- 2012-01-17 SG SG2013052493A patent/SG191892A1/en unknown
- 2012-01-17 AU AU2012209853A patent/AU2012209853B2/en active Active
- 2012-01-17 MY MYPI2013002602A patent/MY163272A/en unknown
- 2012-01-17 ES ES12703898T patent/ES2884825T3/es active Active
- 2012-01-18 JO JOP/2012/0015A patent/JO3508B1/ar active
- 2012-01-20 TW TW101102536A patent/TWI594753B/zh active
- 2012-01-23 AR ARP120100209A patent/AR084914A1/es active IP Right Grant
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2013
- 2013-07-07 IL IL227364A patent/IL227364A/en active IP Right Grant
- 2013-07-10 ZA ZA2013/05199A patent/ZA201305199B/en unknown
- 2013-08-23 CO CO13200028A patent/CO6751272A2/es unknown
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2016
- 2016-06-06 JP JP2016112583A patent/JP6289541B2/ja active Active
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2021
- 2021-06-09 AR ARP210101568A patent/AR122575A2/es unknown
- 2021-08-11 HR HRP20211295TT patent/HRP20211295T1/hr unknown
- 2021-08-23 CY CY20211100751T patent/CY1124447T1/el unknown
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2023
- 2023-04-10 US US18/297,683 patent/US20230381416A1/en active Pending
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