AR121997A2 - Forma cristalina de bencilbenceno inhibidor de sglt2 - Google Patents

Forma cristalina de bencilbenceno inhibidor de sglt2

Info

Publication number
AR121997A2
AR121997A2 ARP210101202A ARP210101202A AR121997A2 AR 121997 A2 AR121997 A2 AR 121997A2 AR P210101202 A ARP210101202 A AR P210101202A AR P210101202 A ARP210101202 A AR P210101202A AR 121997 A2 AR121997 A2 AR 121997A2
Authority
AR
Argentina
Prior art keywords
crystalline form
benzylbenzene
sglt2
inhibitor
xrpd
Prior art date
Application number
ARP210101202A
Other languages
English (en)
Inventor
Mengzhuang Cai
Qian Liu
Ge Xu
Binhua Lv
Brian Seed
Jacques Y Roberge
Original Assignee
Theracos Sub Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45097470&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR121997(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Theracos Sub Llc filed Critical Theracos Sub Llc
Publication of AR121997A2 publication Critical patent/AR121997A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/04—Carbocyclic radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification

Abstract

Reivindicación 1: Una forma cristalina del compuesto de la fórmula (1) caracterizada por un XRPD que comprende picos a 11,2, 12,9, 15,5, 17,8, 19,1, 20,0 y 20,7 grados 2q, ± 0,1 grados 2q, en donde dicho XRPD se hace usando radiación CuKₐ₁; o por un espectro Raman que comprende picos a 353, 688 y 825 cm⁻¹.
ARP210101202A 2010-06-12 2021-05-03 Forma cristalina de bencilbenceno inhibidor de sglt2 AR121997A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2010/073865 WO2011153712A1 (en) 2010-06-12 2010-06-12 Crystalline form of benzylbenzene sglt2 inhibitor

Publications (1)

Publication Number Publication Date
AR121997A2 true AR121997A2 (es) 2022-08-03

Family

ID=45097470

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP210101202A AR121997A2 (es) 2010-06-12 2021-05-03 Forma cristalina de bencilbenceno inhibidor de sglt2

Country Status (31)

Country Link
US (4) US8987323B2 (es)
EP (1) EP2580225B1 (es)
JP (1) JP5842191B2 (es)
KR (1) KR101831675B1 (es)
CN (1) CN102933592B (es)
AR (1) AR121997A2 (es)
AU (1) AU2011264220B2 (es)
BR (1) BR112012031616A2 (es)
CA (1) CA2800379C (es)
CO (1) CO6640246A2 (es)
CY (1) CY1120690T1 (es)
DK (1) DK2580225T3 (es)
ES (1) ES2683123T3 (es)
HR (1) HRP20181695T1 (es)
HU (1) HUE040355T2 (es)
IL (1) IL223205B (es)
LT (1) LT2580225T (es)
MA (1) MA34371B1 (es)
MX (1) MX342665B (es)
MY (1) MY184925A (es)
NZ (1) NZ605570A (es)
PL (1) PL2580225T3 (es)
PT (1) PT2580225T (es)
RS (1) RS57653B1 (es)
RU (1) RU2569491C2 (es)
SG (1) SG186206A1 (es)
SI (1) SI2580225T1 (es)
TW (1) TWI589295B (es)
UA (1) UA108887C2 (es)
WO (2) WO2011153712A1 (es)
ZA (1) ZA201300004B (es)

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HUE064190T2 (hu) * 2013-04-04 2024-03-28 Boehringer Ingelheim Vetmedica Gmbh Lófélék anyagcserezavarainak kezelése
WO2015051484A1 (en) 2013-10-12 2015-04-16 Theracos, Inc. Preparation of hydroxy-benzylbenzene derivatives
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CN108239055B (zh) * 2016-12-23 2023-07-18 杭州领业医药科技有限公司 一种thr1442 l-天冬氨酸共晶、其制备方法及药物组合物
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GB202213849D0 (en) * 2022-09-22 2022-11-09 Macfarlan Smith Ltd Crystalline forms of bexagliflozin, processes for the preparation and use thereof

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