AR118457A1 - Detergentes alternativos para la inactivación viral - Google Patents
Detergentes alternativos para la inactivación viralInfo
- Publication number
- AR118457A1 AR118457A1 ARP200100788A ARP200100788A AR118457A1 AR 118457 A1 AR118457 A1 AR 118457A1 AR P200100788 A ARP200100788 A AR P200100788A AR P200100788 A ARP200100788 A AR P200100788A AR 118457 A1 AR118457 A1 AR 118457A1
- Authority
- AR
- Argentina
- Prior art keywords
- cas
- recombinant protein
- interest
- fluid
- detergent
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
- C12N2740/13061—Methods of inactivation or attenuation
- C12N2740/13063—Methods of inactivation or attenuation by chemical treatment
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Water Supply & Treatment (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Detergent Compositions (AREA)
Abstract
Detergentes para su uso para inactivar virus con envuelta, incluyendo detergentes que se consideran respetuosos con el medio ambiente y que pueden usarse en las operaciones de fabricación biológica. Reivindicación 1: Un método para inactivar virus con envuelta en un fluido que se sabe o se sospecha que contiene al menos un virus con envuelta, que comprende obtener un fluido que se sabe o se sospecha que contiene al menos un virus con envuelta; exponer el fluido a un detergente de la Tabla 1; a una concentración y durante un tiempo suficiente para provocar la inactivación viral. Reivindicación 24: Un método para inactivar virus con envuelta durante purificación de una proteína de interés recombinante que comprende obtener un fluido que comprende la proteína de interés recombinante que se sabe o se sospecha que contiene al menos un virus; someter el fluido a al menos un detergente, en el que el detergente tiene un número de registro de CAS de CAS 3055-99-0, CAS 3055-98-9, CAS 9043-30-5, CAS 85618-20-8, CAS 181135-58-0, CAS 181135-57-9, CAS 250692-65-0, CAS 228579-27-9, CAS 349477-49-2, CAS 70504-28-8, CAS 59080-45-4, CAS 69984-73-2, CAS 148616-91-5, CAS 148565-55-3, CAS 69227-93-6, CAS 82494-09-5, CAS 253678-67-0, CAS 106402-05-5, o CAS 93911-12-7 a una concentración y durante un tiempo suficiente para provocar la inactivación de virus con envuelta en el fluido; y someter el fluido inactivado viral a al menos una operación unitaria que incluye al menos una etapa de filtración o una etapa de cromatografía. Reivindicación 40: Método para producir una proteína de interés recombinante aislada y purificada que comprende establecer un cultivo celular en un biorreactor con una célula huésped que expresa una proteína recombinante y cultivar las células para expresar la proteína de interés recombinante; colectar fluido del cultivo celular que contiene la proteína de interés recombinante; someter el fluido colectado que contiene la proteína de interés recombinante a un detergente que tiene un número de registro de CAS de CAS 3055-99-0, CAS 3055-98-9, CAS 9043-30-5, CAS 85618-20-8, CAS 181135-58-0, CAS 181135-57-9, CAS 250692-65-0, CAS 228579-27-9, CAS 349477-49-2, CAS 70504-28-8, CAS 59080-45-4, CAS 69984-73-2, CAS 148616-91-5, CAS 148565-55-3, CAS 69227-93-6, CAS 82494-09-5, CAS 253678-67-0, CAS 106402-05-5, o CAS 93911-12-7, a una concentración de detergente y durante un tiempo suficiente para provocar la inactivación del virus con envuelta; procesar el fluido inactivado viral que contiene la proteína de interés recombinante a través de al menos dos operaciones unitarias adicionales; y obtener una proteína de interés recombinante aislada y purificada.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962820330P | 2019-03-19 | 2019-03-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR118457A1 true AR118457A1 (es) | 2021-10-06 |
Family
ID=70293063
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP200100788A AR118457A1 (es) | 2019-03-19 | 2020-03-19 | Detergentes alternativos para la inactivación viral |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20220106573A1 (es) |
| EP (1) | EP3941928A1 (es) |
| JP (1) | JP2022525361A (es) |
| KR (1) | KR20210142670A (es) |
| CN (1) | CN113412270A (es) |
| AR (1) | AR118457A1 (es) |
| AU (1) | AU2020240034A1 (es) |
| CA (1) | CA3133794A1 (es) |
| IL (1) | IL285222A (es) |
| MA (1) | MA55371A (es) |
| MX (1) | MX2021011352A (es) |
| SG (1) | SG11202109801YA (es) |
| TW (1) | TW202102518A (es) |
| WO (1) | WO2020190985A1 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023115027A2 (en) * | 2021-12-16 | 2023-06-22 | Bristol-Myers Squibb Company | Detergent for viral inactivation |
| US20240076709A1 (en) | 2022-09-06 | 2024-03-07 | Amgen Inc. | Lean perfusion cell culture methods |
| WO2024059235A2 (en) | 2022-09-16 | 2024-03-21 | Amgen Inc. | A method for harvesting products from perfusion cultures |
| WO2024115344A1 (en) * | 2022-11-29 | 2024-06-06 | Merck Patent Gmbh | Method for inactivating enveloped viruses |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6319494B1 (en) | 1990-12-14 | 2001-11-20 | Cell Genesys, Inc. | Chimeric chains for receptor-associated signal transduction pathways |
| IL104570A0 (en) | 1992-03-18 | 1993-05-13 | Yeda Res & Dev | Chimeric genes and cells transformed therewith |
| US8609602B2 (en) * | 2010-07-14 | 2013-12-17 | Anatrace Products, Llc | Cleaning solution |
| BR112013015113B1 (pt) * | 2010-12-15 | 2023-01-31 | Takeda Pharmaceutical Company Limited | Método de inativar um vírus contendo envelope lipídico |
| JP6465800B2 (ja) | 2012-08-06 | 2019-02-06 | バイオジェン・エムエイ・インコーポレイテッドＢｉｏｇｅｎ ＭＡ Ｉｎｃ． | エンベロープウイルスを不活化するための方法および組成物 |
| KR102238133B1 (ko) | 2013-11-15 | 2021-04-09 | 제넨테크, 인크. | 환경-친화적 세제를 사용한 바이러스 불활성화 방법 |
-
2020
- 2020-03-18 CN CN202080012904.XA patent/CN113412270A/zh active Pending
- 2020-03-18 JP JP2021555791A patent/JP2022525361A/ja active Pending
- 2020-03-18 MX MX2021011352A patent/MX2021011352A/es unknown
- 2020-03-18 CA CA3133794A patent/CA3133794A1/en active Pending
- 2020-03-18 EP EP20719809.4A patent/EP3941928A1/en active Pending
- 2020-03-18 SG SG11202109801Y patent/SG11202109801YA/en unknown
- 2020-03-18 US US17/432,156 patent/US20220106573A1/en active Pending
- 2020-03-18 AU AU2020240034A patent/AU2020240034A1/en active Pending
- 2020-03-18 MA MA055371A patent/MA55371A/fr unknown
- 2020-03-18 KR KR1020217033019A patent/KR20210142670A/ko active Search and Examination
- 2020-03-18 WO PCT/US2020/023245 patent/WO2020190985A1/en active Application Filing
- 2020-03-19 TW TW109109156A patent/TW202102518A/zh unknown
- 2020-03-19 AR ARP200100788A patent/AR118457A1/es unknown
-
2021
- 2021-07-29 IL IL285222A patent/IL285222A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA3133794A1 (en) | 2020-09-24 |
| IL285222A (en) | 2021-09-30 |
| EP3941928A1 (en) | 2022-01-26 |
| KR20210142670A (ko) | 2021-11-25 |
| MA55371A (fr) | 2022-01-26 |
| JP2022525361A (ja) | 2022-05-12 |
| US20220106573A1 (en) | 2022-04-07 |
| TW202102518A (zh) | 2021-01-16 |
| CN113412270A (zh) | 2021-09-17 |
| MX2021011352A (es) | 2021-10-13 |
| SG11202109801YA (en) | 2021-10-28 |
| WO2020190985A1 (en) | 2020-09-24 |
| AU2020240034A1 (en) | 2021-08-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR118457A1 (es) | Detergentes alternativos para la inactivación viral | |
| Wang et al. | Exosomes mediate intercellular transmission of porcine reproductive and respiratory syndrome virus | |
| DK0891420T3 (da) | Fremgangsmåde til replikation af influenzavirus i cellekultur samt de ved fremgangsmåden opnåelige influenzavirus | |
| Domanska-Blicharz et al. | H5N1 high pathogenicity avian influenza virus survival in different types of water | |
| Lee et al. | Robust and persistent SARS-CoV-2 infection in the human intestinal brush border expressing cells | |
| DE60130987D1 (de) | Assemblierung von wildtyp und chimären influenzavirus-ähnlichen partikeln (vlps) | |
| DE50214416D1 (de) | Vermehrung von viren in zellkultur | |
| ES2421543T3 (es) | Método para la preparación de virus y proteínas del PRRS, y kits de pruebas de diagnóstico para su detección | |
| Barqasho et al. | Implications of the release of high-mobility group box 1 protein from dying cells during human immunodeficiency virus type 1 infection in vitro | |
| MX2019015304A (es) | Amortiguador de lavado para cromatografia de intercambio cationico. | |
| EA201270214A1 (ru) | Способы очистки рекомбинантного adamts13 и других белков и их композиции | |
| DK1939281T4 (da) | Immortaliserede andecellelinjer til virusproduktion | |
| ATE355380T1 (de) | Methode zur selektiven inaktivierung der viralen replication | |
| AR071220A1 (es) | Astrovirus aviario depositado bajo el nuero cncm i-3895 | |
| Caballero et al. | Robustness of nanofiltration for increasing the viral safety margin of biological products | |
| Fridmann-Sirkis et al. | Efficiency in complexity: composition and dynamic nature of mimivirus replication factories | |
| CO7151484A2 (es) | Filtración de virus de medios de cultivo celular | |
| RU2012130928A (ru) | Способ культивирования адгезионных клеток | |
| Cipriano et al. | Effectiveness of various processing steps for viral clearance of therapeutic proteins: database analyses of commonly used steps | |
| Moscoso et al. | Molecular analysis of infectious bursal disease virus from bursal tissues collected on FTA® filter paper | |
| AR072150A1 (es) | Metodo de replicacion del virus de la influenza en suspension | |
| TW201704467A (zh) | 用於純化體外產生的病毒的方法及對於病毒的清除測定 | |
| CN102242173B (zh) | 一种石斑鱼虹彩病毒囊膜蛋白的提取方法 | |
| Mathew et al. | Ultraviolet inactivation of chikungunya virus | |
| ES2074968B1 (es) | Nuevas cepas de pseudomonas aeruginosa atenuadas. |