AR112431A1 - Variante de aspartoquinasa y método para producir l-aminoácido usando la misma - Google Patents

Variante de aspartoquinasa y método para producir l-aminoácido usando la misma

Info

Publication number
AR112431A1
AR112431A1 ARP180101815A AR112431A1 AR 112431 A1 AR112431 A1 AR 112431A1 AR P180101815 A ARP180101815 A AR P180101815A AR 112431 A1 AR112431 A1 AR 112431A1
Authority
AR
Argentina
Prior art keywords
amino acid
variant
aspartokinase
produce
same
Prior art date
Application number
Other languages
English (en)
Inventor
Jin Sook Chang
Ji Sun Lee
Chang Il Seo
Hyun Ah Kim
Hyun Won Bae
Hyo Jin Kim
Hyung Joon Kim
Original Assignee
Cj Cheiljedang Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cj Cheiljedang Corp filed Critical Cj Cheiljedang Corp
Publication of AR112431A1 publication Critical patent/AR112431A1/es

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1217—Phosphotransferases with a carboxyl group as acceptor (2.7.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/001—Amines; Imines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/12—Methionine; Cysteine; Cystine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/02—Phosphotransferases with a carboxy group as acceptor (2.7.2)
    • C12Y207/02004—Aspartate kinase (2.7.2.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/02—Phosphotransferases with a carboxy group as acceptor (2.7.2)
    • C12Y207/02003—Phosphoglycerate kinase (2.7.2.3)

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

La presente descripción se refiere a una variante de aspartoquinasa, un microorganismo que comprende la variante, y un método para producir un L-aminoácido derivado de aspartato o un derivado de homoserina de este mediante el uso del microorganismo. Reivindicación 3: Un microorganismo del género Corynebacterium, que produce un L-aminoácido derivado de aspartato o un derivado de aminoácido de este que comprende la variante de aspartoquinasa de la reivindicación 1.
ARP180101815 2017-06-30 2018-06-29 Variante de aspartoquinasa y método para producir l-aminoácido usando la misma AR112431A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020170083437A KR102011994B1 (ko) 2017-06-30 2017-06-30 신규한 아스파토키나제 변이체 및 이를 이용한 l-아미노산의 제조방법

Publications (1)

Publication Number Publication Date
AR112431A1 true AR112431A1 (es) 2019-10-30

Family

ID=64742506

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP180101815 AR112431A1 (es) 2017-06-30 2018-06-29 Variante de aspartoquinasa y método para producir l-aminoácido usando la misma

Country Status (20)

Country Link
US (1) US10662450B2 (es)
EP (1) EP3517607B1 (es)
JP (1) JP6759484B1 (es)
KR (1) KR102011994B1 (es)
CN (1) CN110168083B (es)
AR (1) AR112431A1 (es)
AU (1) AU2018293281B2 (es)
BR (1) BR112019018036B8 (es)
DK (1) DK3517607T3 (es)
ES (1) ES2884800T3 (es)
HU (1) HUE054725T2 (es)
MX (1) MX2019014609A (es)
MY (1) MY195408A (es)
PH (1) PH12019502673A1 (es)
PL (1) PL3517607T3 (es)
RU (1) RU2730025C1 (es)
SG (1) SG11201912130RA (es)
TW (1) TWI718385B (es)
WO (1) WO2019004778A2 (es)
ZA (1) ZA201907864B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102153534B1 (ko) 2019-09-02 2020-09-09 씨제이제일제당 주식회사 신규한 프로모터 및 이를 이용한 아미노산 생산 방법
KR102183209B1 (ko) 2019-09-09 2020-11-26 씨제이제일제당 주식회사 L-쓰레오닌 배출 단백질의 변이체 및 이를 이용한 l-쓰레오닌 생산 방법
KR102182497B1 (ko) 2019-12-20 2020-11-24 씨제이제일제당 주식회사 내막 단백질의 변이체 및 이를 이용한 목적 산물 생산 방법
KR102207867B1 (ko) 2020-01-21 2021-01-26 씨제이제일제당 주식회사 Nadp 의존적 글리세르알데하이드-3-포스페이트 디하이드로지나제를 포함하는 미생물을 이용하여 ｌ-아미노산을 생산하는 방법
KR102285951B1 (ko) * 2020-01-30 2021-08-04 씨제이제일제당 주식회사 시트레이트 신타아제의 활성이 약화된 신규한 변이형 폴리펩티드 및 이를 이용한 l-아미노산 생산 방법
CA3199126A1 (en) 2020-12-11 2022-06-16 Byoung Hoon Yoon Mutant atp-dependent protease, and method for producing l-amino acid using same
KR102464883B1 (ko) 2020-12-11 2022-11-09 씨제이제일제당 주식회사 신규한 감마-아미노부티르산 퍼미에이즈 변이체 및 이를 이용한 이소류신 생산 방법
KR102470602B1 (ko) 2020-12-11 2022-11-25 씨제이제일제당 주식회사 신규한 분지 연쇄 아미노산 아미노트렌스퍼라아제 변이체 및 이를 이용한 이소류신 생산 방법
CN114585734B (zh) * 2021-01-25 2022-11-04 Cj第一制糖株式会社 新型水解酶变体及使用其生产l-色氨酸的方法
CN114450400B (zh) * 2021-01-25 2022-10-04 Cj第一制糖株式会社 新型铜转运p型atp酶a变体及使用其生产l-色氨酸的方法
KR102377745B1 (ko) 2021-05-12 2022-03-23 씨제이제일제당 주식회사 신규 프로모터 및 이의 용도
KR102685904B1 (ko) 2021-05-20 2024-07-19 씨제이제일제당 주식회사 신규 프로모터 및 이의 용도

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3473042B2 (ja) * 1992-04-28 2003-12-02 味の素株式会社 変異型アスパルトキナーゼ遺伝子
ATE203769T1 (de) * 1992-11-10 2001-08-15 Ajinomoto Kk Dna, die aspartokinase iii-mutanten kodiert und ihre verwendung zur herstellung von l-threonin durch fermentation
JPH07155184A (ja) * 1993-12-08 1995-06-20 Ajinomoto Co Inc 発酵法によるｌ−リジンの製造法
JP4075087B2 (ja) * 1996-12-05 2008-04-16 味の素株式会社 Ｌ−リジンの製造法
RU2224793C1 (ru) * 2000-01-21 2004-02-27 Адзиномото Ко., Инк. Способ получения l-лизина
BRPI0016995B1 (pt) * 2000-01-21 2016-03-08 Ajinomoto Kk bactéria escherichia coli geneticamente modificada, e, método para produzir l-lisina
AU2002325923A1 (en) * 2001-08-06 2003-05-19 Degussa Ag Production of l-lysine by genetically modified corynebacterium glutamicum strains
JP2007068437A (ja) * 2005-09-05 2007-03-22 Chisso Corp 変異型アスパルトキナーゼとその利用方法
KR100838038B1 (ko) 2006-12-29 2008-06-12 씨제이제일제당 (주) Ｌ-라이신 생산능이 향상된 코리네박테리움 속 미생물 및그를 이용한 ｌ-라이신 생산 방법
US9005952B2 (en) * 2008-04-04 2015-04-14 Cj Cheiljedang Corporation Microorganism producing L-methionine precursor and the method of producing L-methionine precursor using the microorganism
KR101512432B1 (ko) * 2010-06-15 2015-04-16 백광산업 주식회사 미생물을 이용한 아스파테이트 계열 아미노산의 생산방법

Also Published As

Publication number Publication date
ES2884800T3 (es) 2021-12-13
EP3517607B1 (en) 2021-05-05
KR20190003019A (ko) 2019-01-09
EP3517607A2 (en) 2019-07-31
ZA201907864B (en) 2020-08-26
EP3517607A4 (en) 2020-05-13
SG11201912130RA (en) 2020-01-30
US10662450B2 (en) 2020-05-26
JP6759484B1 (ja) 2020-09-23
AU2018293281A1 (en) 2019-12-12
WO2019004778A3 (ko) 2019-03-28
US20200131545A1 (en) 2020-04-30
DK3517607T3 (da) 2021-07-26
BR112019018036B8 (pt) 2022-03-29
MX2019014609A (es) 2020-02-07
BR112019018036B1 (pt) 2022-03-22
TWI718385B (zh) 2021-02-11
AU2018293281B2 (en) 2022-02-03
MY195408A (en) 2023-01-19
CN110168083A (zh) 2019-08-23
CN110168083B (zh) 2020-10-27
BR112019018036A2 (pt) 2020-04-07
WO2019004778A2 (ko) 2019-01-03
PL3517607T3 (pl) 2021-12-20
RU2730025C1 (ru) 2020-08-14
HUE054725T2 (hu) 2021-09-28
JP2020202834A (ja) 2020-12-24
PH12019502673A1 (en) 2020-06-08
KR102011994B1 (ko) 2019-08-20
TW201907002A (zh) 2019-02-16

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