AR107494A1 - Proceso para la preparación de osimertinib (azd9291) o una sal del mismo, y azd9291 anilina o una sal de la misma - Google Patents
Proceso para la preparación de osimertinib (azd9291) o una sal del mismo, y azd9291 anilina o una sal de la mismaInfo
- Publication number
- AR107494A1 AR107494A1 ARP170100246A ARP170100246A AR107494A1 AR 107494 A1 AR107494 A1 AR 107494A1 AR P170100246 A ARP170100246 A AR P170100246A AR P170100246 A ARP170100246 A AR P170100246A AR 107494 A1 AR107494 A1 AR 107494A1
- Authority
- AR
- Argentina
- Prior art keywords
- azd9291
- salt
- aniline
- preparation
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662289390P | 2016-02-01 | 2016-02-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR107494A1 true AR107494A1 (es) | 2018-05-02 |
Family
ID=57984913
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP170100246A AR107494A1 (es) | 2016-02-01 | 2017-01-31 | Proceso para la preparación de osimertinib (azd9291) o una sal del mismo, y azd9291 anilina o una sal de la misma |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US11180477B2 (https=) |
| EP (1) | EP3411038B1 (https=) |
| JP (1) | JP6812449B2 (https=) |
| KR (1) | KR102749892B1 (https=) |
| CN (1) | CN108495632B (https=) |
| AR (1) | AR107494A1 (https=) |
| AU (1) | AU2017214243B2 (https=) |
| BR (1) | BR112018014712B1 (https=) |
| CA (1) | CA3011809C (https=) |
| CO (1) | CO2018007008A2 (https=) |
| ES (1) | ES2834608T3 (https=) |
| IL (1) | IL260665B (https=) |
| MX (1) | MX378363B (https=) |
| MY (1) | MY185367A (https=) |
| RU (1) | RU2733376C2 (https=) |
| TW (1) | TWI745345B (https=) |
| WO (1) | WO2017134051A1 (https=) |
| ZA (1) | ZA201805790B (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2017269335B2 (en) | 2016-05-26 | 2021-07-01 | Recurium Ip Holdings, Llc | EGFR inhibitor compounds |
| CN107556293B (zh) * | 2017-09-19 | 2019-12-03 | 福建省微生物研究所 | 一种奥西替尼的合成工艺 |
| WO2021111462A1 (en) * | 2019-12-02 | 2021-06-10 | Natco Pharma Limited | An improved process for the preparation of osimertinib mesylate |
| US11780824B2 (en) * | 2020-12-16 | 2023-10-10 | Scinopharm Taiwan, Ltd. | Process for preparing osimertinib or a salt thereof |
| KR20240055046A (ko) | 2021-09-02 | 2024-04-26 | 신톤 비.브이. | 오시머티닙을 제조하는 방법 |
| WO2025124936A1 (en) | 2023-12-15 | 2025-06-19 | Synthon B.V. | A process for making osimertinib |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4070401A (en) * | 1972-02-19 | 1978-01-24 | Mitsui Toatsu Chemicals Inc. | Method for the preparation of a halogenated aromatic amine |
| CN103702990B (zh) | 2011-07-27 | 2015-09-09 | 阿斯利康(瑞典)有限公司 | 2-(2,4,5-取代苯胺)嘧啶衍生物作为egfr调谐子用于治疗癌症 |
| CN110526912B (zh) * | 2014-06-19 | 2023-02-14 | 武田药品工业株式会社 | 用于激酶抑制的杂芳基化合物 |
| CN104817541B (zh) * | 2015-05-11 | 2017-06-16 | 苏州东南药业股份有限公司 | 一种抗肿瘤药物的合成方法 |
-
2017
- 2017-01-26 TW TW106103351A patent/TWI745345B/zh active
- 2017-01-31 BR BR112018014712-5A patent/BR112018014712B1/pt active IP Right Grant
- 2017-01-31 RU RU2018130327A patent/RU2733376C2/ru active
- 2017-01-31 JP JP2018538156A patent/JP6812449B2/ja active Active
- 2017-01-31 CN CN201780007929.9A patent/CN108495632B/zh active Active
- 2017-01-31 WO PCT/EP2017/052050 patent/WO2017134051A1/en not_active Ceased
- 2017-01-31 MX MX2018008966A patent/MX378363B/es unknown
- 2017-01-31 ES ES17703696T patent/ES2834608T3/es active Active
- 2017-01-31 MY MYPI2018702645A patent/MY185367A/en unknown
- 2017-01-31 KR KR1020187025038A patent/KR102749892B1/ko active Active
- 2017-01-31 US US16/074,119 patent/US11180477B2/en active Active
- 2017-01-31 CA CA3011809A patent/CA3011809C/en active Active
- 2017-01-31 AU AU2017214243A patent/AU2017214243B2/en active Active
- 2017-01-31 EP EP17703696.9A patent/EP3411038B1/en active Active
- 2017-01-31 AR ARP170100246A patent/AR107494A1/es active IP Right Grant
-
2018
- 2018-07-04 CO CONC2018/0007008A patent/CO2018007008A2/es unknown
- 2018-07-19 IL IL260665A patent/IL260665B/en unknown
- 2018-08-29 ZA ZA2018/05790A patent/ZA201805790B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2834608T3 (es) | 2021-06-18 |
| RU2018130327A (ru) | 2020-03-04 |
| AU2017214243A1 (en) | 2018-09-06 |
| MX378363B (es) | 2025-03-10 |
| CN108495632B (zh) | 2021-12-31 |
| TWI745345B (zh) | 2021-11-11 |
| BR112018014712A2 (pt) | 2018-12-11 |
| TW201736364A (zh) | 2017-10-16 |
| JP2019508387A (ja) | 2019-03-28 |
| WO2017134051A1 (en) | 2017-08-10 |
| US20210122734A1 (en) | 2021-04-29 |
| MY185367A (en) | 2021-05-11 |
| RU2018130327A3 (https=) | 2020-03-26 |
| MX2018008966A (es) | 2018-09-03 |
| RU2733376C2 (ru) | 2020-10-01 |
| CA3011809C (en) | 2024-02-27 |
| KR20180101610A (ko) | 2018-09-12 |
| US11180477B2 (en) | 2021-11-23 |
| BR112018014712B1 (pt) | 2023-10-31 |
| IL260665B (en) | 2021-08-31 |
| AU2017214243B2 (en) | 2019-07-18 |
| JP6812449B2 (ja) | 2021-01-13 |
| KR102749892B1 (ko) | 2025-01-07 |
| EP3411038B1 (en) | 2020-09-09 |
| CN108495632A (zh) | 2018-09-04 |
| EP3411038A1 (en) | 2018-12-12 |
| ZA201805790B (en) | 2024-10-30 |
| CO2018007008A2 (es) | 2018-07-19 |
| CA3011809A1 (en) | 2017-08-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR107494A1 (es) | Proceso para la preparación de osimertinib (azd9291) o una sal del mismo, y azd9291 anilina o una sal de la misma | |
| AR076027A1 (es) | Metodos e intermediarios para la preparacion de agentes farmaceuticos | |
| AR126445A2 (es) | Metodo para preparar inhibidores de btk | |
| AR093244A1 (es) | Compuestos de benceno sustituidos utilizables en el tratamiento de trastornos mediados por ezh2 | |
| PE20170300A1 (es) | Procesos para preparar un inhibidor de jak 1 y nuevas formas de este | |
| AR074845A1 (es) | Procedimiento de sintesis de la ivabradina y de sus sales de adicion a un acido farmaceuticamente aceptable | |
| AR079491A1 (es) | Metodos de sintesis de inhibidores del factor xa tal como el betrixaban y composiciones farmaceuticas que contienen la base libre de betrixaban o su sal sustancialmente pura. | |
| PE20180327A1 (es) | Proceso para preparar 4-amino-piridazinas | |
| AR078916A1 (es) | Procedimiento para la purificacion de paliperidona | |
| BR112015029714A2 (pt) | processo para preparar derivados de 4,6-bis(ariloxi)pirimidina | |
| BR112012017994B8 (pt) | composição líquida, uso de uma composição líquida, e, métodos para preparar uma composição líquida e para tratamento de um distúrbio | |
| AR080921A1 (es) | Proceso para la preparacion de amidas de acido pirazolcarboxilico | |
| MX394430B (es) | Proceso para la preparación de 5-fluoro-1h-pirazoles. | |
| AR109248A1 (es) | Procedimiento para la preparación de 4-fenilbutirato y sus usos | |
| AR101136A1 (es) | Proceso para la preparación de ácidos 3-hidroxipicolínicos | |
| MX2017006298A (es) | Proceso para producir acido acetico introduciendo un compuesto de litio. | |
| AR087345A1 (es) | Metodos para la preparacion de compuestos de tiofeno | |
| AR066054A1 (es) | Proceso para preparar galantamina | |
| MX2018004338A (es) | Proceso para sintesis de pirfenidona. | |
| MX383794B (es) | Procedimiento para la preparacion de un derivado de furfural. | |
| ES2531069T3 (es) | Proceso para la producción de tartrato de L-carnitina | |
| AR102980A1 (es) | Un proceso para la fabricación de idalopirdina | |
| AR106195A1 (es) | Proceso para la preparación de ácido 1-(4-metanosulfonil-2-trifluorometil-bencil)-2-metil-1h-pirrolo[2,3-b]piridin-3-il-acético e intermediarios de dicha síntesis | |
| AR093373A1 (es) | Procedimiento de sintesis del (2e)-3-(3,4-dimetoxifenil)prop-2-enonitrilo y aplicacion a la sintesis de la ivabradina y de sus sales de adicion a un acido farmaceuticamente aceptable | |
| AR089376A1 (es) | Proceso para la preparacion de oxido estanico |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |