AR104212A1 - Formulaciones inyectables de liberación extendida que comprenden un agente activo de isoxazolina, métodos y usos de las mismas - Google Patents

Formulaciones inyectables de liberación extendida que comprenden un agente activo de isoxazolina, métodos y usos de las mismas

Info

Publication number
AR104212A1
AR104212A1 ARP160100953A ARP160100953A AR104212A1 AR 104212 A1 AR104212 A1 AR 104212A1 AR P160100953 A ARP160100953 A AR P160100953A AR P160100953 A ARP160100953 A AR P160100953A AR 104212 A1 AR104212 A1 AR 104212A1
Authority
AR
Argentina
Prior art keywords
isoxazoline
methods
active agent
liberation
extended
Prior art date
Application number
ARP160100953A
Other languages
English (en)
Inventor
Le Hir De Fallois Loic
Galeska Izabela
Cheifetz Peter
Mancini Cady Susan
Original Assignee
Merial Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial Inc filed Critical Merial Inc
Publication of AR104212A1 publication Critical patent/AR104212A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Formulaciones inyectables de liberación extendida para combatir parásitos en animales, que comprenden al menos un agente activo de isoxazolina, un polímero farmacéuticamente aceptable y un solvente. Métodos para erradicar, controlar y prevenir infecciones e infestaciones por parásitos en un animal que comprende administrar las formulaciones inyectables de liberación extendida de la presente a un animal que lo necesita.
ARP160100953A 2015-04-08 2016-04-08 Formulaciones inyectables de liberación extendida que comprenden un agente activo de isoxazolina, métodos y usos de las mismas AR104212A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562144871P 2015-04-08 2015-04-08

Publications (1)

Publication Number Publication Date
AR104212A1 true AR104212A1 (es) 2017-07-05

Family

ID=57072717

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP160100953A AR104212A1 (es) 2015-04-08 2016-04-08 Formulaciones inyectables de liberación extendida que comprenden un agente activo de isoxazolina, métodos y usos de las mismas

Country Status (18)

Country Link
US (2) US20170020848A1 (es)
EP (1) EP3280413A1 (es)
JP (2) JP6824900B2 (es)
KR (1) KR102593069B1 (es)
CN (1) CN108055825B (es)
AR (1) AR104212A1 (es)
AU (3) AU2016246598B2 (es)
BR (1) BR112017021073A2 (es)
CA (1) CA2981797C (es)
CL (1) CL2017002536A1 (es)
CO (1) CO2017010065A2 (es)
EA (2) EA202090762A1 (es)
IL (1) IL254813B (es)
MX (2) MX2017012848A (es)
NZ (1) NZ736374A (es)
SG (2) SG10201912724SA (es)
UY (1) UY36610A (es)
WO (1) WO2016164487A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY37137A (es) * 2016-02-24 2017-09-29 Merial Inc Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
JP7222909B2 (ja) * 2017-04-05 2023-02-15 ベーリンガー・インゲルハイム・アニマル・ヘルス・ユーエスエー・インコーポレイテッド （ｓ）－アフォキソラネルの結晶形
WO2018189314A1 (en) 2017-04-13 2018-10-18 Ceva Sante Animale Composition for treating worms infestations
BR112020008853A2 (pt) 2017-11-07 2020-10-13 Intervet International B.V. composições farmacêuticas injetáveis de isoxazolina e seu uso contra infestação parasitária
AU2018363686B2 (en) 2017-11-07 2023-11-23 Intervet International B.V. Process for preparing large size isoxazoline particles
BR112020011506A2 (pt) * 2017-12-12 2020-11-17 Intervet International B.V. composições farmacêuticas de isoxazolina implantáveis e usos das mesmas
TWI812673B (zh) * 2018-02-12 2023-08-21 美商富曼西公司 用於防治無脊椎害蟲之萘異噁唑啉化合物
AR116524A1 (es) * 2018-10-04 2021-05-19 Elanco Tiergesundheit Ag Potenciación de tratamiento de helmintos
MX2021013429A (es) 2019-05-03 2021-12-10 Intervet Int Bv Composiciones farmaceuticas inyectables y usos de las mismas.
EP4153133B1 (en) * 2020-05-20 2023-11-08 Intervet International B.V. Injectable pharmaceutical compositions and uses thereof
IL309666A (en) 2021-07-09 2024-02-01 Plexium Inc Aryl compounds and pharmaceutical preparations that modulate IKZF2

Family Cites Families (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3740421A (en) 1966-09-19 1973-06-19 Basf Wyandotte Corp Polyoxyethylene-polyoxypropylene aqueous gels
JPS4914624A (es) 1972-06-08 1974-02-08
US3950360A (en) 1972-06-08 1976-04-13 Sankyo Company Limited Antibiotic substances
SE434277B (sv) 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
US4134973A (en) 1977-04-11 1979-01-16 Merck & Co., Inc. Carbohydrate derivatives of milbemycin and processes therefor
US4199569A (en) 1977-10-03 1980-04-22 Merck & Co., Inc. Selective hydrogenation products of C-076 compounds and derivatives thereof
US4144352A (en) 1977-12-19 1979-03-13 Merck & Co., Inc. Milbemycin compounds as anthelmintic agents
US4203976A (en) 1978-08-02 1980-05-20 Merck & Co., Inc. Sugar derivatives of C-076 compounds
JPS57139012A (en) 1981-02-23 1982-08-27 Sankyo Co Ltd Anthelmintic composition
US4427663A (en) 1982-03-16 1984-01-24 Merck & Co., Inc. 4"-Keto-and 4"-amino-4"-deoxy avermectin compounds and substituted amino derivatives thereof
ATE67493T1 (de) 1985-02-04 1991-10-15 Bayer Agrochem Kk Heterocyclische verbindungen.
EP0237482A1 (de) 1986-03-06 1987-09-16 Ciba-Geigy Ag C(29)-Carbonyloxi-milbemycin-Derivate zur Bekämpfung von tier- und pflanzenparasitären Schädlingen
EP0246739B1 (en) 1986-03-25 1991-01-23 Sankyo Company Limited Macrolide compounds, their preparation and their use
ATE75745T1 (de) 1986-07-02 1992-05-15 Ciba Geigy Ag Pestizide.
US4855317A (en) 1987-03-06 1989-08-08 Ciba-Geigy Corporation Insecticides and parasiticides
US4871719A (en) 1987-03-24 1989-10-03 Ciba-Geigy Corporation Composition for controlling parasites in productive livestock
US4874749A (en) 1987-07-31 1989-10-17 Merck & Co., Inc. 4"-Deoxy-4-N-methylamino avermectin Bla/Blb
DE3888936T2 (de) 1987-11-03 1994-07-21 Beecham Group Plc Zwischenprodukte für die Herstellung makrolider Antibiotika mit anthelmintischer Wirkung.
NZ232422A (en) 1989-02-16 1992-11-25 Merck & Co Inc 13-ketal milbemycin derivatives and parasiticides
NZ247278A (en) 1991-02-12 1995-03-28 Ancare Distributors Veterinary anthelmintic drench comprising a suspension of praziquantel in a liquid carrier
US5330768A (en) 1991-07-05 1994-07-19 Massachusetts Institute Of Technology Controlled drug delivery using polymer/pluronic blends
US5345377A (en) 1992-10-30 1994-09-06 Electric Power Research Institute, Inc. Harmonic controller for an active power line conditioner
GB9300883D0 (en) 1993-01-18 1993-03-10 Pfizer Ltd Antiparasitic agents
AUPM969994A0 (en) 1994-11-28 1994-12-22 Virbac S.A. Equine anthelmintic formulations
US6207647B1 (en) 1997-07-18 2001-03-27 Smithkline Beecham Corporation RatA
US6733767B2 (en) * 1998-03-19 2004-05-11 Merck & Co., Inc. Liquid polymeric compositions for controlled release of bioactive substances
EA011764B1 (ru) 2004-03-05 2009-06-30 Ниссан Кемикал Индастриз, Лтд. Изоксазолинзамещённое производное бензамида и пестицид
US8362086B2 (en) 2005-08-19 2013-01-29 Merial Limited Long acting injectable formulations
AU2006285613B2 (en) 2005-09-02 2011-11-17 Nissan Chemical Corporation Isoxazoline-substituted benzamide compound and harmful organism-controlling agent
KR20080080168A (ko) 2005-12-14 2008-09-02 이 아이 듀폰 디 네모아 앤드 캄파니 무척추 해충 방제용 이속사졸린
TW200803740A (en) 2005-12-16 2008-01-16 Du Pont 5-aryl isoxazolines for controlling invertebrate pests
TWI412322B (zh) 2005-12-30 2013-10-21 Du Pont 控制無脊椎害蟲之異唑啉
KR20090005201A (ko) 2006-04-20 2009-01-12 이 아이 듀폰 디 네모아 앤드 캄파니 무척추 해충 방제용 피라졸린
JP2008044880A (ja) 2006-08-15 2008-02-28 Bayer Cropscience Ag 殺虫性イソオキサゾリン類
JP5256753B2 (ja) 2007-03-29 2013-08-07 住友化学株式会社 イソオキサゾリン化合物とその有害生物防除用途
RU2009141185A (ru) 2007-04-10 2011-05-20 Байер КропСайенс АГ (DE) Инсектицидные производные арилизоксазолина
EP2155701B1 (en) 2007-06-13 2013-12-11 E. I. Du Pont de Nemours and Company Isoxazoline insecticides
TWI430995B (zh) * 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
TWI556741B (zh) * 2007-08-17 2016-11-11 英特威特國際股份有限公司 異唑啉組成物及其作為抗寄生蟲藥上的應用
CN101809004B (zh) 2007-10-03 2012-12-26 杜邦公司 用于控制无脊椎害虫的萘异噁唑啉化合物
EP2306837B2 (en) 2008-07-09 2023-10-25 Basf Se Pesticidal active mixtures comprising isoxazoline compounds i
WO2010079077A1 (en) * 2008-12-18 2010-07-15 Novartis Ag Isoxazolines derivatives and their use as pesticide
ES2569486T3 (es) * 2009-12-17 2016-05-11 Merial, Inc. Compuestos de dihidroazol antiparasitarios y composiciones que comprenden los mismos
ES2566402T3 (es) * 2010-05-27 2016-04-12 E. I. Du Pont De Nemours And Company Forma cristalina de 4-[5-[3-cloro-5-(trifluorometil)fenil]-4,5-dihidro-5-(trifluorometil)-3-isoxazolil]-N-[2-oxo-2-[(2,2,2-trifluoroetil)amino]etil]-1-naftalenocarboxamida
DK178277B1 (da) * 2010-06-18 2015-10-26 Novartis Tiergesundheit Ag Diaryloxazolinforbindelser til bekæmpelse af fiskelus
WO2012089623A1 (en) 2010-12-27 2012-07-05 Intervet International B.V. Topical localized isoxazoline formulation comprising glycofurol
CA2826067A1 (en) * 2011-02-10 2012-08-16 Novartis Ag Isoxazoline derivatives for controlling invertebrate pests
RU2013145304A (ru) 2011-03-10 2015-04-20 Новартис Аг Производные изоксазола
ME02412B (me) 2011-03-10 2016-09-20 Zoetis Services Llc Spirociklični derivati izoksazolina kao antiparazitska sredstva
AU2012308776B2 (en) * 2011-09-12 2016-04-14 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising an isoxazoline active agent, methods and uses thereof
AR088669A1 (es) * 2011-11-21 2014-06-25 Lilly Co Eli Derivados de dihidrodibenzo[c][1,2]oxaborol y dihidroisoxazol utiles para el control de ectoparasitos
AR088668A1 (es) * 2011-11-21 2014-06-25 Lilly Co Eli Moleculas pequeñas que contienen boro
ES2659159T3 (es) * 2011-12-02 2018-03-14 Merial, Inc. Formulaciones de moxidectina inyectable de acción prolongada y nuevas formas cristalinas de moxidectina
TR201902125T4 (tr) 2012-02-06 2019-03-21 Merial Inc Si̇stemi̇k olarak etki̇ eden akti̇f ajanlari i̇çeren parazi̇ti̇si̇dal oral veteri̇nerli̇ğe ai̇t bi̇leşi̇mler, bunlarin yöntemleri̇ ve kullanimlari
CA2882546A1 (en) 2012-09-07 2014-03-13 Zoetis Llc Spirocyclic isoxazolines as antiparasitic agents
SI2892347T1 (sl) 2012-09-07 2019-10-30 Zoetis Services Llc Paraziticidne kombinacije spirocikličnega isoksazolina
AR096346A1 (es) 2013-05-20 2015-12-23 Zoetis Llc Composiciones antiparasitarias de espiro-isoxazolina de acción prolongada
MX2016004035A (es) * 2013-09-30 2016-06-02 Zoetis Services Llc Formulaciones de espiro-isoxazolina de accion prolongada.

Also Published As

Publication number Publication date
MX2022010831A (es) 2022-09-29
IL254813B (en) 2020-03-31
EA201792235A1 (ru) 2018-01-31
AU2020210266B2 (en) 2022-03-10
BR112017021073A2 (pt) 2018-07-03
EA036272B1 (ru) 2020-10-21
AU2022202035A1 (en) 2022-04-14
KR20170134700A (ko) 2017-12-06
CO2017010065A2 (es) 2018-01-05
AU2016246598A1 (en) 2017-11-02
EA202090762A1 (ru) 2020-09-08
CA2981797C (en) 2023-11-21
AU2020210266A1 (en) 2020-08-20
CN108055825B (zh) 2021-03-30
SG10201912724SA (en) 2020-02-27
US20210299104A1 (en) 2021-09-30
EP3280413A1 (en) 2018-02-14
WO2016164487A1 (en) 2016-10-13
US20170020848A1 (en) 2017-01-26
NZ736374A (en) 2024-02-23
IL254813A0 (en) 2017-12-31
AU2016246598B2 (en) 2020-07-23
JP6824900B2 (ja) 2021-02-03
JP2021050206A (ja) 2021-04-01
SG11201708068PA (en) 2017-10-30
JP2018510897A (ja) 2018-04-19
CA2981797A1 (en) 2016-10-13
KR102593069B1 (ko) 2023-10-23
UY36610A (es) 2016-10-31
CN108055825A (zh) 2018-05-18
CL2017002536A1 (es) 2018-04-20
MX2017012848A (es) 2018-01-15

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