AR095348A1 - Medios de cultivo celular y métodos de producción de anticuerpos - Google Patents
Medios de cultivo celular y métodos de producción de anticuerposInfo
- Publication number
- AR095348A1 AR095348A1 ARP140101052A ARP140101052A AR095348A1 AR 095348 A1 AR095348 A1 AR 095348A1 AR P140101052 A ARP140101052 A AR P140101052A AR P140101052 A ARP140101052 A AR P140101052A AR 095348 A1 AR095348 A1 AR 095348A1
- Authority
- AR
- Argentina
- Prior art keywords
- cell culture
- culture media
- antibody production
- production methods
- methods
- Prior art date
Links
- 239000006143 cell culture medium Substances 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 230000016784 immunoglobulin production Effects 0.000 title 1
- 238000000034 method Methods 0.000 abstract 2
- 238000004113 cell culture Methods 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0681—Cells of the genital tract; Non-germinal cells from gonads
- C12N5/0682—Cells of the female genital tract, e.g. endometrium; Non-germinal cells from ovaries, e.g. ovarian follicle cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/32—Amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/33—Insulin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/998—Proteins not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Reproductive Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361801247P | 2013-03-15 | 2013-03-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR095348A1 true AR095348A1 (es) | 2015-10-07 |
Family
ID=51537877
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP140101052A AR095348A1 (es) | 2013-03-15 | 2014-03-14 | Medios de cultivo celular y métodos de producción de anticuerpos |
Country Status (12)
| Country | Link |
|---|---|
| US (5) | US9441035B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2968544A4 (cg-RX-API-DMAC7.html) |
| JP (2) | JP2016513478A (cg-RX-API-DMAC7.html) |
| KR (1) | KR102202476B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN105246510A (cg-RX-API-DMAC7.html) |
| AR (1) | AR095348A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112015022529A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2903589A1 (cg-RX-API-DMAC7.html) |
| HK (1) | HK1213179A1 (cg-RX-API-DMAC7.html) |
| MX (1) | MX366112B (cg-RX-API-DMAC7.html) |
| RU (1) | RU2015144020A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2014145091A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20200768T4 (hr) | 2009-08-11 | 2025-03-28 | F. Hoffmann - La Roche Ag | Proizvodnja proteina u mediju za uzgoj stanica bez glutamina |
| KR102007930B1 (ko) | 2014-12-31 | 2019-08-06 | 주식회사 엘지화학 | 재조합 당단백질의 글리코실화 조절 방법 |
| AR104050A1 (es) * | 2015-03-26 | 2017-06-21 | Chugai Pharmaceutical Co Ltd | Proceso de producción con iones de cobre controlados |
| JP7073363B2 (ja) * | 2016-11-07 | 2022-05-23 | シージェン インコーポレイテッド | 工学的に操作されたシステインキャップの分配 |
| GB201708655D0 (en) * | 2017-05-31 | 2017-07-12 | Ucb Biopharma Sprl | Cell culture methods |
| CN115925882A (zh) | 2017-12-22 | 2023-04-07 | 瑞泽恩制药公司 | 用于表征药物产品杂质的系统和方法 |
| CN111500662A (zh) * | 2018-06-25 | 2020-08-07 | 深圳市菲鹏生物制药股份有限公司 | 调节cho-k1表达系统所分泌抗体的酸性峰含量的方法 |
| US20240043486A1 (en) * | 2020-12-08 | 2024-02-08 | Partner Therapeutics, Inc. | Manufacture of granulocyte macrophage-colony stimulating factor |
| US20220251502A1 (en) * | 2020-12-22 | 2022-08-11 | Novartis Ag | Methods for reducing the oxidation level of cysteine residues in a secreted recombinantly-expressed protein during cell culture |
| MX2023012903A (es) * | 2021-05-03 | 2023-11-08 | Boehringer Ingelheim Int | Metodo para producir spesolimab. |
| US20250136931A1 (en) * | 2022-04-06 | 2025-05-01 | Kashiv Biosciences, Llc | An improved cell culture process for production of protein |
| CN120603928A (zh) * | 2022-11-09 | 2025-09-05 | 伊孚森有限公司 | 避免冷凝的培养箱 |
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| CA2701338C (en) * | 2007-10-15 | 2018-09-18 | Chugai Seiyaku Kabushiki Kaisha | Method for production of antibody |
| JP5705115B2 (ja) | 2008-09-10 | 2015-04-22 | ジェネンテック, インコーポレイテッド | 蛋白質の酸化的分解の予防のための組成物および方法 |
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| SG178078A1 (en) * | 2009-07-24 | 2012-03-29 | Hoffmann La Roche | Optimizing the production of antibodies |
| HRP20200768T4 (hr) * | 2009-08-11 | 2025-03-28 | F. Hoffmann - La Roche Ag | Proizvodnja proteina u mediju za uzgoj stanica bez glutamina |
| JP2013517776A (ja) | 2010-01-25 | 2013-05-20 | ベントリア・バイオサイエンス | タンパク質の生成を改善するための方法および組成物 |
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-
2014
- 2014-03-14 EP EP14763258.2A patent/EP2968544A4/en not_active Withdrawn
- 2014-03-14 US US14/211,467 patent/US9441035B2/en active Active
- 2014-03-14 RU RU2015144020A patent/RU2015144020A/ru not_active Application Discontinuation
- 2014-03-14 HK HK16101113.2A patent/HK1213179A1/zh unknown
- 2014-03-14 AR ARP140101052A patent/AR095348A1/es unknown
- 2014-03-14 WO PCT/US2014/029758 patent/WO2014145091A1/en not_active Ceased
- 2014-03-14 KR KR1020157029225A patent/KR102202476B1/ko active Active
- 2014-03-14 CA CA2903589A patent/CA2903589A1/en not_active Abandoned
- 2014-03-14 MX MX2015011781A patent/MX366112B/es active IP Right Grant
- 2014-03-14 BR BR112015022529A patent/BR112015022529A2/pt not_active Application Discontinuation
- 2014-03-14 JP JP2016503216A patent/JP2016513478A/ja active Pending
- 2014-03-14 CN CN201480027392.9A patent/CN105246510A/zh active Pending
-
2015
- 2015-09-11 US US14/852,382 patent/US20160102141A1/en not_active Abandoned
-
2016
- 2016-07-29 US US15/224,113 patent/US20170051049A1/en not_active Abandoned
-
2019
- 2019-06-18 JP JP2019112773A patent/JP2019193643A/ja active Pending
- 2019-10-18 US US16/657,844 patent/US20200291103A1/en not_active Abandoned
- 2019-11-15 US US16/685,798 patent/US20200347122A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20140308273A1 (en) | 2014-10-16 |
| US20160102141A1 (en) | 2016-04-14 |
| JP2016513478A (ja) | 2016-05-16 |
| MX366112B (es) | 2019-06-26 |
| US9441035B2 (en) | 2016-09-13 |
| EP2968544A1 (en) | 2016-01-20 |
| US20200347122A1 (en) | 2020-11-05 |
| CA2903589A1 (en) | 2014-09-18 |
| WO2014145091A1 (en) | 2014-09-18 |
| US20200291103A1 (en) | 2020-09-17 |
| RU2015144020A (ru) | 2017-04-21 |
| JP2019193643A (ja) | 2019-11-07 |
| BR112015022529A2 (pt) | 2017-07-18 |
| US20170051049A1 (en) | 2017-02-23 |
| HK1213179A1 (zh) | 2016-06-30 |
| MX2015011781A (es) | 2016-04-04 |
| KR20150131258A (ko) | 2015-11-24 |
| CN105246510A (zh) | 2016-01-13 |
| EP2968544A4 (en) | 2016-10-12 |
| KR102202476B1 (ko) | 2021-01-12 |
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