AR080172A1 - (r) -4- ((4-((4-(tetrahidrofuran-3-iloxi) benzo (d) isoxazol-3-iloxi)metil)piperidin-1-il)metil) tetrahidro-2h-piran-4-ol, un agonista parcial de receptores 5-ht4 y composiciones farmaceuticas que los comprenden - Google Patents
(r) -4- ((4-((4-(tetrahidrofuran-3-iloxi) benzo (d) isoxazol-3-iloxi)metil)piperidin-1-il)metil) tetrahidro-2h-piran-4-ol, un agonista parcial de receptores 5-ht4 y composiciones farmaceuticas que los comprendenInfo
- Publication number
- AR080172A1 AR080172A1 ARP110100443A ARP110100443A AR080172A1 AR 080172 A1 AR080172 A1 AR 080172A1 AR P110100443 A ARP110100443 A AR P110100443A AR P110100443 A ARP110100443 A AR P110100443A AR 080172 A1 AR080172 A1 AR 080172A1
- Authority
- AR
- Argentina
- Prior art keywords
- iloxi
- methyl
- piran
- isoxazol
- piperidin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/423—Oxazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Se describe en el presente documento (R)-4-((4-((4-(tetrahidrofuran-3- iloxi)benzo[d]isoxazol-3-iloxi)metil)piperidin-1 -il)metil)tetrahidro-2H-piran-4-oI y su uso en el tratamiento de trastornos neurodegenerativos. Reivindicacion 2: Un compuesto de formula (I) o una sal farmacéuticamente aceptable del mismo.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US30492110P | 2010-02-16 | 2010-02-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR080172A1 true AR080172A1 (es) | 2012-03-21 |
Family
ID=43904611
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP110100443A AR080172A1 (es) | 2010-02-16 | 2011-02-14 | (r) -4- ((4-((4-(tetrahidrofuran-3-iloxi) benzo (d) isoxazol-3-iloxi)metil)piperidin-1-il)metil) tetrahidro-2h-piran-4-ol, un agonista parcial de receptores 5-ht4 y composiciones farmaceuticas que los comprenden |
Country Status (15)
Country | Link |
---|---|
US (1) | US20120041026A1 (es) |
EP (1) | EP2536713A1 (es) |
JP (1) | JP2013519722A (es) |
KR (1) | KR20120123089A (es) |
CN (1) | CN102762554A (es) |
AR (1) | AR080172A1 (es) |
AU (1) | AU2011216950A1 (es) |
CA (1) | CA2788656A1 (es) |
IN (1) | IN2012DN06631A (es) |
MX (1) | MX2012008721A (es) |
SG (1) | SG183111A1 (es) |
TW (1) | TW201141856A (es) |
UY (1) | UY33225A (es) |
WO (1) | WO2011101774A1 (es) |
ZA (1) | ZA201206469B (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9737531B2 (en) | 2012-07-12 | 2017-08-22 | Glytech, Llc | Composition and method for treatment of depression and psychosis in humans |
US10583138B2 (en) | 2012-07-12 | 2020-03-10 | Glytech, Llc | Composition and method for treatment of depression and psychosis in humans |
BR112013029319A2 (pt) * | 2011-05-18 | 2017-01-31 | Raqualia Pharma Inc | forma polimorfa i de ácido 4-{[4-({[4-(2,2,2-trifluoroetoxi)-1,2-benzisoxazol-3-il]oxi}metil)piperidina-1-il]metil}-tetrahidro-2h-pirano-4 carboxílico, forma polimorfa ii de ácido 4-{[4-({[4-(2,2,2-trifluoroetoxi)-1,2-benzisoxazol-3-il]oxi}metil)piperidina-1-il]metil}-tetrahidro-2h-pirano-4 carboxílico, uso e processo, e método para tratar condições de doença mediadas por atividade receptora de 5-ht4 |
RU2659036C2 (ru) * | 2012-11-21 | 2018-06-27 | Раквалиа Фарма Инк. | Полиморфные формы |
IN2013CH01199A (es) | 2013-03-20 | 2015-08-14 | Suven Life Sciences Ltd | |
CA2932428C (en) | 2013-12-16 | 2017-10-24 | Suven Life Sciences Limited | Indazole compounds as 5-ht4 receptor agonists |
JP6572414B2 (ja) * | 2014-05-20 | 2019-09-11 | ラクオリア創薬株式会社 | ベンズイソオキサゾール誘導体塩 |
EP3265459B1 (en) | 2015-02-13 | 2019-05-15 | Suven Life Sciences Limited | Amide compounds as 5-ht4 receptor agonists |
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NZ243065A (en) * | 1991-06-13 | 1995-07-26 | Lundbeck & Co As H | Piperidine derivatives and pharmaceutical compositions |
CA2149918A1 (en) * | 1992-11-23 | 1994-06-09 | Mark G. Palermo | Substituted 3-(aminoalkylamino)-1,2-benzisoxazoles and related compounds |
IL117149A0 (en) | 1995-02-23 | 1996-06-18 | Schering Corp | Muscarinic antagonists |
US5889006A (en) | 1995-02-23 | 1999-03-30 | Schering Corporation | Muscarinic antagonists |
BR9610733A (pt) | 1995-09-29 | 1999-07-13 | Glaxo Wellcome Spa | Composto processos para a preparação do mesmo e para o tratamento de um mamífero composição farmacêutica e utilização de um composto |
IL126003A0 (en) | 1996-04-10 | 1999-04-11 | Hoechst Marion Roussel Inc | Spiro [cyclopent [b] indole-piperidines] and n-[phenyl-hydrazon intermediates for their preparation both being acetyl cholinesterase and mao inhibitors |
DE69707659T2 (de) | 1996-04-12 | 2002-05-08 | Aventis Pharma Inc | Isatinderivate als acetylcholinesterase-inhibitoren und analgetika |
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JP3390179B2 (ja) | 1996-08-15 | 2003-03-24 | シェーリング コーポレイション | エーテルムスカリン様アンタゴニスト |
KR20000048715A (ko) | 1996-09-30 | 2000-07-25 | 게리 디. 스트리트, 스티븐 엘. 네스비트 | Nmda (n-메틸-d-아스파르테이트) 길항제 |
WO2000018391A1 (fr) | 1998-09-30 | 2000-04-06 | Takeda Chemical Industries, Ltd. | Medicaments qui ameliorent le pouvoir de vidange de la vessie |
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-
2011
- 2011-02-09 IN IN6631DEN2012 patent/IN2012DN06631A/en unknown
- 2011-02-09 CA CA2788656A patent/CA2788656A1/en not_active Abandoned
- 2011-02-09 WO PCT/IB2011/050548 patent/WO2011101774A1/en active Application Filing
- 2011-02-09 MX MX2012008721A patent/MX2012008721A/es not_active Application Discontinuation
- 2011-02-09 JP JP2012553423A patent/JP2013519722A/ja not_active Withdrawn
- 2011-02-09 SG SG2012053906A patent/SG183111A1/en unknown
- 2011-02-09 EP EP11710564A patent/EP2536713A1/en not_active Withdrawn
- 2011-02-09 CN CN2011800099647A patent/CN102762554A/zh active Pending
- 2011-02-09 AU AU2011216950A patent/AU2011216950A1/en not_active Abandoned
- 2011-02-09 KR KR1020127021310A patent/KR20120123089A/ko not_active Application Discontinuation
- 2011-02-14 UY UY0001033225A patent/UY33225A/es not_active Application Discontinuation
- 2011-02-14 AR ARP110100443A patent/AR080172A1/es not_active Application Discontinuation
- 2011-02-15 TW TW100104942A patent/TW201141856A/zh unknown
- 2011-02-16 US US13/028,368 patent/US20120041026A1/en not_active Abandoned
-
2012
- 2012-08-28 ZA ZA2012/06469A patent/ZA201206469B/en unknown
Also Published As
Publication number | Publication date |
---|---|
UY33225A (es) | 2011-09-30 |
CA2788656A1 (en) | 2011-08-25 |
EP2536713A1 (en) | 2012-12-26 |
TW201141856A (en) | 2011-12-01 |
JP2013519722A (ja) | 2013-05-30 |
IN2012DN06631A (es) | 2015-10-23 |
KR20120123089A (ko) | 2012-11-07 |
ZA201206469B (en) | 2013-05-29 |
CN102762554A (zh) | 2012-10-31 |
MX2012008721A (es) | 2012-08-17 |
SG183111A1 (en) | 2012-09-27 |
US20120041026A1 (en) | 2012-02-16 |
WO2011101774A1 (en) | 2011-08-25 |
AU2011216950A1 (en) | 2012-08-23 |
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