IN2012DN06631A - - Google Patents

Info

Publication number
IN2012DN06631A
IN2012DN06631A IN6631DEN2012A IN2012DN06631A IN 2012DN06631 A IN2012DN06631 A IN 2012DN06631A IN 6631DEN2012 A IN6631DEN2012 A IN 6631DEN2012A IN 2012DN06631 A IN2012DN06631 A IN 2012DN06631A
Authority
IN
India
Prior art keywords
yloxy
methyl
isoxazol
pyran
piperidin
Prior art date
Application number
Inventor
Hirohide Noguchi
Nobuaki Waizumi
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IN2012DN06631A publication Critical patent/IN2012DN06631A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/423—Oxazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Abstract

(R) 4 ((4 ((4 (tetrahydrofuran 3 yloxy)benzo[d]isoxazol 3 yloxy)methyl)piperidin 1 yl)methyl)tetrahydro 2H pyran 4 ol and its use in treating neurodegenerative disorders is described herein.
IN6631DEN2012 2010-02-16 2011-02-09 IN2012DN06631A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30492110P 2010-02-16 2010-02-16
PCT/IB2011/050548 WO2011101774A1 (en) 2010-02-16 2011-02-09 (r)-4-((4-((4-(tetrahydrofuran-3-yloxy)benzo[d]isoxazol-3-yloxy)methyl)piperidin-1-yl)methyl)tetrahydro-2h-pyran-4-ol, a partial agonist of 5-ht4 receptors

Publications (1)

Publication Number Publication Date
IN2012DN06631A true IN2012DN06631A (en) 2015-10-23

Family

ID=43904611

Family Applications (1)

Application Number Title Priority Date Filing Date
IN6631DEN2012 IN2012DN06631A (en) 2010-02-16 2011-02-09

Country Status (15)

Country Link
US (1) US20120041026A1 (en)
EP (1) EP2536713A1 (en)
JP (1) JP2013519722A (en)
KR (1) KR20120123089A (en)
CN (1) CN102762554A (en)
AR (1) AR080172A1 (en)
AU (1) AU2011216950A1 (en)
CA (1) CA2788656A1 (en)
IN (1) IN2012DN06631A (en)
MX (1) MX2012008721A (en)
SG (1) SG183111A1 (en)
TW (1) TW201141856A (en)
UY (1) UY33225A (en)
WO (1) WO2011101774A1 (en)
ZA (1) ZA201206469B (en)

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* Cited by examiner, † Cited by third party
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US9737531B2 (en) 2012-07-12 2017-08-22 Glytech, Llc Composition and method for treatment of depression and psychosis in humans
US10583138B2 (en) 2012-07-12 2020-03-10 Glytech, Llc Composition and method for treatment of depression and psychosis in humans
BR112013029319A2 (en) * 2011-05-18 2017-01-31 Raqualia Pharma Inc 4 - {[4 - ({[4- (2,2,2-trifluoroethoxy) -1,2-benzisoxazol-3-yl] oxy} methyl) piperidin-1-yl] methyl} -tetrahydroic acid polymorphic form 2h-pyran-4-carboxylic acid, 4 - {[4 - ({[4- (2,2,2-trifluoroethoxy) -1,2-benzisoxazol-3-yl] oxy} methyl) piperidine acid 1-yl] methyl} -tetrahydro-2h-pyran-4 carboxylic acid, use and process, and method for treating disease conditions mediated by 5-ht4 receptor activity
CA2890861C (en) * 2012-11-21 2021-03-30 Raqualia Pharma Inc. Polymorphic forms of 4-{[4-({[4-(2,2,2-trifluoroethoxy)-1,2-benzisoxazol-3-yl]oxy}methyl)piperidin-1-yl]methyl}-tetrahydro-2h-pyran-4-carboxylic acid
JP6185650B2 (en) 2013-03-20 2017-08-23 スヴェン・ライフ・サイエンシズ・リミテッド 5-Amino-quinoline-8-carboxamide derivatives as 5-HT4 receptor agonists
AU2014369085B2 (en) 2013-12-16 2017-02-23 Suven Life Sciences Limited Indazole compounds as 5-HT4 receptor agonists
KR102471082B1 (en) * 2014-05-20 2022-11-25 라퀄리아 파마 인코포레이티드 Benzisoxazole derivative salt
EA034618B1 (en) 2015-02-13 2020-02-27 Сувен Лайф Сайенсиз Лимитед Amide compounds as 5-htreceptor agonists

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Also Published As

Publication number Publication date
JP2013519722A (en) 2013-05-30
AR080172A1 (en) 2012-03-21
SG183111A1 (en) 2012-09-27
TW201141856A (en) 2011-12-01
ZA201206469B (en) 2013-05-29
US20120041026A1 (en) 2012-02-16
WO2011101774A1 (en) 2011-08-25
KR20120123089A (en) 2012-11-07
AU2011216950A1 (en) 2012-08-23
EP2536713A1 (en) 2012-12-26
CN102762554A (en) 2012-10-31
MX2012008721A (en) 2012-08-17
UY33225A (en) 2011-09-30
CA2788656A1 (en) 2011-08-25

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