AR069085A1 - Anticuerpos especificos de los peptidos beta- amiloides y sus usos como agentes de diagnostico o drogas - Google Patents

Anticuerpos especificos de los peptidos beta- amiloides y sus usos como agentes de diagnostico o drogas

Info

Publication number
AR069085A1
AR069085A1 ARP080104708A ARP080104708A AR069085A1 AR 069085 A1 AR069085 A1 AR 069085A1 AR P080104708 A ARP080104708 A AR P080104708A AR P080104708 A ARP080104708 A AR P080104708A AR 069085 A1 AR069085 A1 AR 069085A1
Authority
AR
Argentina
Prior art keywords
mammal
antibody
abeta8
level
peptides
Prior art date
Application number
ARP080104708A
Other languages
English (en)
Spanish (es)
Inventor
Eugeen Vanmechelen
Andre Delacourte
Pierre Gronet
Veronique Blanchard-Bregeon
Luc Bluee
Marie Gompel
Nicolas Sergeant
Laurent Pradier
Original Assignee
Sanofi Aventis
Inst Nat Sante Rech Med
Innogenetics Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38925731&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR069085(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Aventis, Inst Nat Sante Rech Med, Innogenetics Nv filed Critical Sanofi Aventis
Publication of AR069085A1 publication Critical patent/AR069085A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711Alzheimer's disease; Amyloid plaque core protein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ARP080104708A 2007-10-29 2008-10-28 Anticuerpos especificos de los peptidos beta- amiloides y sus usos como agentes de diagnostico o drogas AR069085A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP07119537 2007-10-29

Publications (1)

Publication Number Publication Date
AR069085A1 true AR069085A1 (es) 2009-12-30

Family

ID=38925731

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP080104708A AR069085A1 (es) 2007-10-29 2008-10-28 Anticuerpos especificos de los peptidos beta- amiloides y sus usos como agentes de diagnostico o drogas

Country Status (27)

Country Link
US (1) US8343493B2 (de)
EP (1) EP2205633A1 (de)
JP (1) JP5421277B2 (de)
KR (1) KR20100097651A (de)
CN (1) CN101883792B (de)
AP (1) AP2957A (de)
AR (1) AR069085A1 (de)
AU (1) AU2008317705B2 (de)
CA (1) CA2703825A1 (de)
CL (1) CL2008003197A1 (de)
CO (1) CO6270369A2 (de)
CR (1) CR11396A (de)
EA (1) EA201070539A1 (de)
EC (1) ECSP10010142A (de)
HN (1) HN2010000880A (de)
IL (1) IL205398A0 (de)
MA (1) MA31793B1 (de)
MX (1) MX2010004660A (de)
MY (1) MY155144A (de)
NI (1) NI201000075A (de)
NZ (1) NZ585000A (de)
TN (1) TN2010000197A1 (de)
TW (1) TW200936605A (de)
UA (1) UA103602C2 (de)
UY (1) UY31433A1 (de)
WO (1) WO2009056490A1 (de)
ZA (1) ZA201002989B (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4275747A2 (de) 2016-07-19 2023-11-15 Duke University Therapeutische anwendungen von cpf1-basierter genomeditierung

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL199534A (en) 2007-01-05 2013-01-31 Univ Zuerich An isolated human antibody capable of detecting a neoepitope in a disease-related protein, a polynucleotide encoding an antibody, a vector containing the polynucleotide, a host cell containing the polynucleotide or vector, a preparation containing the antibody and related methods and uses.
AU2008203703C1 (en) * 2007-01-05 2014-04-03 University Of Zurich Method of providing disease-specific binding molecules and targets
CA2746778C (en) 2008-12-19 2019-04-23 University Of Zurich Human anti-alpha-synuclein autoantibodies
US8486940B2 (en) 2009-09-11 2013-07-16 Probiodrug Ag Inhibitors
PE20130527A1 (es) 2010-03-03 2013-05-09 Boehringer Ingelheim Int Polipeptidos de union a a-beta biparatopicos
EP2511296A1 (de) * 2011-04-12 2012-10-17 Araclón Biotech, S. L. Antikörper, Kit und Verfahren zur Bestimmung von Amyloidpeptiden
CA2839563C (en) 2011-06-23 2019-10-29 Biogen Idec International Neuroscience Gmbh Anti-alpha synuclein binding molecules
EP3269736B1 (de) 2012-05-10 2019-11-27 Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin Konformationsspezifische antikörper gegen amyloid (beta)-oligomere
MA41115A (fr) 2014-12-02 2017-10-10 Biogen Int Neuroscience Gmbh Procédé de traitement de la maladie d'alzheimer
JP7448174B2 (ja) * 2015-11-09 2024-03-12 ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア アミロイドベータ中間領域エピトープおよびそれに対する立体配座選択的抗体
JP2019533426A (ja) 2016-07-18 2019-11-21 ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア アミロイドベータに対する抗体
JOP20200041A1 (ar) 2017-08-22 2020-02-20 Biogen Ma Inc تركيبات صيدلية تحتوي على أجسام مضادة لبيتا نشوي
PL3461819T3 (pl) 2017-09-29 2020-11-30 Probiodrug Ag Inhibitory cyklazy glutaminylowej
EP4448564A1 (de) * 2021-12-17 2024-10-23 F. Hoffmann-La Roche AG Neuer antikörper zum nachweis von amyloid beta 42 (a-beta42)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2487528A1 (en) * 2002-07-24 2004-02-12 Innogenetics N.V. Prevention, treatment and diagnosis of diseases associated with beta-amyloid formation and/or aggregation
DE10303974A1 (de) * 2003-01-31 2004-08-05 Abbott Gmbh & Co. Kg Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4275747A2 (de) 2016-07-19 2023-11-15 Duke University Therapeutische anwendungen von cpf1-basierter genomeditierung

Also Published As

Publication number Publication date
ZA201002989B (en) 2011-07-27
NZ585000A (en) 2012-08-31
UA103602C2 (ru) 2013-11-11
TN2010000197A1 (en) 2011-11-11
AU2008317705A1 (en) 2009-05-07
CN101883792A (zh) 2010-11-10
AP2957A (en) 2014-08-31
UY31433A1 (es) 2009-05-29
IL205398A0 (en) 2010-12-30
CR11396A (es) 2012-10-18
JP2011502139A (ja) 2011-01-20
US8343493B2 (en) 2013-01-01
ECSP10010142A (es) 2010-07-30
JP5421277B2 (ja) 2014-02-19
CO6270369A2 (es) 2011-04-20
US20110059092A1 (en) 2011-03-10
EP2205633A1 (de) 2010-07-14
CA2703825A1 (en) 2009-05-07
CL2008003197A1 (es) 2010-01-15
KR20100097651A (ko) 2010-09-03
WO2009056490A1 (en) 2009-05-07
MA31793B1 (fr) 2010-10-01
HN2010000880A (es) 2014-03-10
TW200936605A (en) 2009-09-01
CN101883792B (zh) 2014-08-27
AU2008317705B2 (en) 2014-06-05
MX2010004660A (es) 2010-07-30
AP2010005249A0 (en) 2010-06-30
NI201000075A (es) 2010-09-23
MY155144A (en) 2015-09-15
EA201070539A1 (ru) 2010-10-29

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