AR068187A1 - Forma cristalina de un intermediario sintetico para la preparacion de un inhibidor de dpp-iv - Google Patents

Forma cristalina de un intermediario sintetico para la preparacion de un inhibidor de dpp-iv

Info

Publication number
AR068187A1
AR068187A1 ARP080102995A ARP080102995A AR068187A1 AR 068187 A1 AR068187 A1 AR 068187A1 AR P080102995 A ARP080102995 A AR P080102995A AR P080102995 A ARP080102995 A AR P080102995A AR 068187 A1 AR068187 A1 AR 068187A1
Authority
AR
Argentina
Prior art keywords
inhibitor
preparation
dpp
crystal form
crystalline form
Prior art date
Application number
ARP080102995A
Other languages
English (en)
Inventor
Zhen-Ping Wu
Original Assignee
Phenomix Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phenomix Corp filed Critical Phenomix Corp
Publication of AR068187A1 publication Critical patent/AR068187A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic System
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds

Abstract

La invencion provee una forma cristalina de un intermediario sintético de utilidad en la preparacion de un inhibidor de DPP-IV, un método de preparacion de la forma cristalina del intermediario y un método de uso de la forma cristalina del intermediario en la preparacion del inhibidor. Utiles para el tratamiento de la diabetes mellitus. Reivindicacion 1: Una forma cristalina de un compuesto de la formula (1).
ARP080102995A 2007-07-12 2008-07-11 Forma cristalina de un intermediario sintetico para la preparacion de un inhibidor de dpp-iv AR068187A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US95922607P 2007-07-12 2007-07-12

Publications (1)

Publication Number Publication Date
AR068187A1 true AR068187A1 (es) 2009-11-11

Family

ID=40229094

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP080102995A AR068187A1 (es) 2007-07-12 2008-07-11 Forma cristalina de un intermediario sintetico para la preparacion de un inhibidor de dpp-iv

Country Status (8)

Country Link
US (1) US20100204484A1 (es)
EP (1) EP2175727A4 (es)
AR (1) AR068187A1 (es)
CA (1) CA2692758A1 (es)
CL (1) CL2008002044A1 (es)
MX (1) MX2010000501A (es)
TW (1) TW200927144A (es)
WO (1) WO2009009751A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY32030A (es) 2008-08-06 2010-03-26 Boehringer Ingelheim Int "tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
WO2010018217A2 (en) 2008-08-15 2010-02-18 Boehringer Ingelheim International Gmbh Organic compounds for wound healing
AR074990A1 (es) 2009-01-07 2011-03-02 Boehringer Ingelheim Int Tratamiento de diabetes en pacientes con un control glucemico inadecuado a pesar de la terapia con metformina
TWI466672B (zh) 2009-01-29 2015-01-01 Boehringer Ingelheim Int 小兒科病人糖尿病之治療
EA029759B1 (ru) 2009-02-13 2018-05-31 Бёрингер Ингельхайм Интернациональ Гмбх Антидиабетические лекарственные средства, содержащие ингибитор dpp-4 (линаглиптин) необязательно в комбинации с другими антидиабетическими средствами
EP3646859A1 (en) 2009-11-27 2020-05-06 Boehringer Ingelheim International GmbH Treatment of genotyped diabetic patients with dpp-iv inhibitors such as linagliptin
US20130109703A1 (en) 2010-03-18 2013-05-02 Boehringer Ingelheim International Gmbh Combination of a GPR119 Agonist and the DPP-IV Inhibitor Linagliptin for Use in the Treatment of Diabetes and Related Conditions
AU2011249722B2 (en) 2010-05-05 2015-09-17 Boehringer Ingelheim International Gmbh Combination therapy
BR112012032579B1 (pt) 2010-06-24 2021-05-11 Boehringer Ingelheim International Gmbh uso de linagliptina e composição farmacêutica compreendendo linagliptina e insulina basal de longa duração
WO2012170702A1 (en) 2011-06-08 2012-12-13 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
WO2013174767A1 (en) 2012-05-24 2013-11-28 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3496163A (en) * 1965-02-08 1970-02-17 Upjohn Co 7-halo-7-deoxylincomycins and process for preparing the same
US5329012A (en) * 1987-10-29 1994-07-12 The Research Foundation Of State University Of New York Bis(acyloxmethyl)imidazole compounds
US20100087658A1 (en) * 1996-08-06 2010-04-08 Phenomix Corporation Methods and intermediates for synthesis of selective dpp-iv inhibitors
US20040077605A1 (en) * 2001-06-20 2004-04-22 Salvati Mark E. Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
US7576121B2 (en) * 2003-11-12 2009-08-18 Phenomix Corporation Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
US7317109B2 (en) * 2003-11-12 2008-01-08 Phenomix Corporation Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
MX2008001612A (es) * 2005-08-01 2008-04-04 Phenomix Corp Metodos para preparar acidos boronicos heterociclicos y derivados de los mismos.
WO2007038676A2 (en) * 2005-09-28 2007-04-05 Teva Pharmaceutical Industries Ltd. Polymorphic forms of ladostigil tartrate

Also Published As

Publication number Publication date
CL2008002044A1 (es) 2009-01-16
US20100204484A1 (en) 2010-08-12
WO2009009751A1 (en) 2009-01-15
EP2175727A4 (en) 2011-05-25
MX2010000501A (es) 2011-05-25
CA2692758A1 (en) 2009-01-15
EP2175727A1 (en) 2010-04-21
TW200927144A (en) 2009-07-01

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