AR065845A1 - Quinolonas y tetrahidroquinolinas y compuestos relacionados con actividad inhibidoria de nos - Google Patents
Quinolonas y tetrahidroquinolinas y compuestos relacionados con actividad inhibidoria de nosInfo
- Publication number
- AR065845A1 AR065845A1 ARP080101216A ARP080101216A AR065845A1 AR 065845 A1 AR065845 A1 AR 065845A1 AR P080101216 A ARP080101216 A AR P080101216A AR P080101216 A ARP080101216 A AR P080101216A AR 065845 A1 AR065845 A1 AR 065845A1
- Authority
- AR
- Argentina
- Prior art keywords
- optionally substituted
- r2nhc
- alkaryl
- alkheterocyclyl
- heterocyclyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Rheumatology (AREA)
- Addiction (AREA)
- Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89682907P | 2007-03-23 | 2007-03-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR065845A1 true AR065845A1 (es) | 2009-07-08 |
Family
ID=39775375
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP080101216A AR065845A1 (es) | 2007-03-23 | 2008-03-25 | Quinolonas y tetrahidroquinolinas y compuestos relacionados con actividad inhibidoria de nos |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8173813B2 (enExample) |
| EP (1) | EP2139886A4 (enExample) |
| JP (1) | JP2010521527A (enExample) |
| CN (1) | CN101679397A (enExample) |
| AR (1) | AR065845A1 (enExample) |
| AU (1) | AU2008232269A1 (enExample) |
| CA (1) | CA2681771A1 (enExample) |
| CL (1) | CL2008000838A1 (enExample) |
| IL (1) | IL201142A (enExample) |
| MX (1) | MX2009010193A (enExample) |
| NZ (1) | NZ580618A (enExample) |
| TW (1) | TWI417099B (enExample) |
| WO (1) | WO2008116308A1 (enExample) |
| ZA (1) | ZA200907458B (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2008321353A1 (en) * | 2007-11-16 | 2009-05-22 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Methods for treating visceral pain |
| CA2705835A1 (en) * | 2007-11-16 | 2009-05-22 | Neuraxon, Inc. | Indole compounds and methods for treating visceral pain |
| AU2009296803A1 (en) * | 2008-09-29 | 2010-04-01 | Merck Sharp & Dohme Corp. | Substituted aryl sulfone derivatives as calcium channel blockers |
| US8198268B2 (en) * | 2008-10-31 | 2012-06-12 | Janssen Biotech, Inc. | Tianeptine sulfate salt forms and methods of making and using the same |
| US20110319416A1 (en) | 2009-01-28 | 2011-12-29 | Emory University | Subunit Selective NMDA Receptor Antagonists For The Treatment Of Neurological Conditions |
| FR2984318B1 (fr) | 2011-12-16 | 2014-06-27 | Oreal | Coupleur de structure 7 amino-1,2,3,4-tetrahydroquinoleines cationiques, composition tinctoriale en comprenant, procedes et utilisations |
| FR2984323B1 (fr) * | 2011-12-16 | 2019-08-30 | L'oreal | Coupleur de structure 7 amino-1,2,3,4-tetrahydroquinoleines, composition tinctoriale en comprenant, procedes et utilisations |
| AU2013369649B2 (en) * | 2012-12-31 | 2018-07-26 | Sunovion Pharmaceuticals Inc. | Heterocyclic compounds and methods of use thereof |
| EP2986587B1 (en) | 2013-04-17 | 2023-11-22 | Sharon Anavi-Goffer | Cb2 receptor ligands for the treatment of psychiatric disorders |
| KR20160023686A (ko) * | 2013-06-26 | 2016-03-03 | 다이이찌 산쿄 가부시키가이샤 | 3 고리성 복소 고리 화합물의 제조 방법 |
| JP6539274B2 (ja) | 2013-08-12 | 2019-07-03 | ファーマシューティカル マニュファクチュアリング リサーチ サービシズ,インコーポレーテッド | 押出成形された即放性乱用抑止性丸剤 |
| US9492444B2 (en) | 2013-12-17 | 2016-11-15 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| WO2015095391A1 (en) | 2013-12-17 | 2015-06-25 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| US10092591B2 (en) | 2014-02-27 | 2018-10-09 | University Of Alaska Fairbanks | Methods and compositions for the treatment of ischemic injury to tissue using therapeutic hypothermia |
| WO2016010771A1 (en) | 2014-07-17 | 2016-01-21 | Pharmaceutical Manufacturing Research Services, Inc. | Immediate release abuse deterrent liquid fill dosage form |
| AU2015336065A1 (en) | 2014-10-20 | 2017-05-04 | Pharmaceutical Manufacturing Research Services, Inc. | Extended release abuse deterrent liquid fill dosage form |
| CN109206385B (zh) * | 2017-07-03 | 2022-04-22 | 扬子江药业集团有限公司 | 一种地佐辛杂质a及其同系物的制备方法 |
| FR3072286B1 (fr) | 2017-10-13 | 2022-08-12 | Oreal | 7-amino-1,2,3,4-tetrahydroquinoleines particuliers, procede et composition |
| CN108853509A (zh) * | 2018-05-03 | 2018-11-23 | 浙江大学 | 抑郁症的治疗和药物组合物 |
| CN109053712A (zh) * | 2018-09-19 | 2018-12-21 | 南京大学连云港高新技术研究院 | 一种2-氨基噻吩-3-羧酸甲酯衍生物c15h22n2o5s的合成方法 |
| KR20210127137A (ko) | 2018-12-05 | 2021-10-21 | 노쓰웨스턴유니버시티 | 면역요법을 위한 뉴런 옥시드 신타제 억제제 |
| WO2021127391A1 (en) * | 2019-12-20 | 2021-06-24 | The Jackson Laboratory | Molecular targets for addiction |
| CN111650307A (zh) * | 2020-07-13 | 2020-09-11 | 重庆医药高等专科学校 | 一种同时对酒中解热镇痛类药品非法添加物定性定量检测的方法及应用 |
| WO2022056736A1 (zh) * | 2020-09-16 | 2022-03-24 | 中国科学院深圳先进技术研究院 | 左氧氟沙星或其药物可接受盐在制备抗脑缺血再灌注损伤的药物或保健品中的应用 |
| CN115073370B (zh) * | 2021-03-10 | 2024-12-17 | 成都硕德药业有限公司 | 新型烷基氨类化合物或盐、异构体、其制备方法及用途 |
| US12213973B2 (en) | 2021-10-18 | 2025-02-04 | Northwestern University | Bacterial nitric oxide synthase inhibitors |
| US20250221959A1 (en) * | 2022-03-17 | 2025-07-10 | Vasoceuticals, Inc. | Combined use of individual compounds for treatment of chronic pain disorders |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4087561A (en) | 1975-12-22 | 1978-05-02 | Canada Packers Limited | Control of nitrosamine formation in nitride cured meat with 1,2,3,4-tetrahydro-quinoline compounds |
| FR2358151A1 (fr) | 1976-03-31 | 1978-02-10 | Roussel Uclaf | Nouvelles benzazepines et leurs sels, procede de preparation et application a titre de medicaments |
| JPS5373571A (en) * | 1976-12-10 | 1978-06-30 | Otsuka Pharmaceut Co Ltd | Carbostyril derivatives |
| AU548467B2 (en) | 1980-08-12 | 1985-12-12 | Glaxo Group Limited | Tryptamines and their isoindolylethyl derivatives |
| JPS57192389A (en) | 1981-05-20 | 1982-11-26 | Takeda Chem Ind Ltd | Novel maytansinoid |
| US4710507A (en) | 1983-12-22 | 1987-12-01 | Pfizer Inc. | Quinolone inotropic agents |
| US4963677A (en) * | 1987-12-30 | 1990-10-16 | Orion Corporation Ltd. | Heterocyclic lactam compounds |
| EP0322746B1 (en) * | 1987-12-30 | 1996-05-29 | Orion Corporation Limited | Heterocyclic compounds |
| US5847006A (en) * | 1991-02-08 | 1998-12-08 | Cambridge Neuroscience, Inc. | Therapeutic guanidines |
| ATE177078T1 (de) * | 1993-10-21 | 1999-03-15 | Searle & Co | Amidino-derivate als no-synthetase inhibitoren |
| ZA95878B (en) * | 1994-02-03 | 1996-01-16 | Cambridge Neuroscience Inc | Therapeutic guanidines |
| MX9605366A (es) * | 1994-05-07 | 1997-12-31 | Astra Ab | Derivados de amidina biciclicos como inhibidores de la oxido nitrico sintetasa. |
| AU730369B2 (en) * | 1996-11-25 | 2001-03-08 | Board Of Regents Of The University Of Nebraska, The | Guanidinyl heterocycle compounds useful as alpha-2 adrenoceptor agonists |
| ID22812A (id) | 1996-11-25 | 1999-12-09 | Procter & Gamble | Senyawa 2-imidazolinilaminoindol yang berguna sebagai agonis adrenoseptor alfa-2 |
| JPH10265450A (ja) * | 1997-03-25 | 1998-10-06 | Mitsui Chem Inc | 一酸化窒素合成酵素阻害作用を有する新規なアミジン誘導体 |
| US6166030A (en) * | 1997-05-05 | 2000-12-26 | Astra Aktiebolag | Compounds |
| FR2783519B1 (fr) * | 1998-09-23 | 2003-01-24 | Sod Conseils Rech Applic | Nouveaux derives d'amidines, leur preparation, leur application a titre de medicaments et les compositions pharmaceutiques les contenant |
| JP2004536079A (ja) * | 2001-05-16 | 2004-12-02 | アンテックスファーマ・インコーポレーテッド | 置換1−ベンズアゼピンおよびその誘導体 |
| AU2002352878B2 (en) | 2001-11-27 | 2007-11-22 | Merck Sharp & Dohme Corp. | 2-Aminoquinoline compounds |
| CA2370751A1 (en) * | 2002-02-05 | 2003-08-05 | Garth B.D. Shoemaker | Fast and accurate rendering of pliable display technology distortions using pre-calculated texel coverages |
| BR0308429A (pt) * | 2002-03-14 | 2005-01-11 | Bayer Healthcare Ag | Aroilpiridinonas monocìclicas como agentes antiinflamatórios |
| US20050171195A1 (en) * | 2003-11-06 | 2005-08-04 | Carroll William A. | P2X7 antagonists for treating neuropathic pain |
| CN101247853B (zh) | 2005-04-13 | 2014-11-12 | 轴突公司 | 具有nos抑制活性的取代的吲哚化合物 |
| WO2007017764A2 (en) * | 2005-05-18 | 2007-02-15 | Neuraxon, Inc. | Substituted benzimidazole compounds with dual nos inhibitory activity and muopioid agonist activity |
| JP2009501184A (ja) | 2005-07-13 | 2009-01-15 | エフ.ホフマン−ラ ロシュ アーゲー | 5−ht6、5−ht24としてのベンゾイミダゾール誘導体 |
-
2008
- 2008-03-24 CL CL200800838A patent/CL2008000838A1/es unknown
- 2008-03-24 US US12/054,083 patent/US8173813B2/en not_active Expired - Fee Related
- 2008-03-24 TW TW097110353A patent/TWI417099B/zh not_active IP Right Cessation
- 2008-03-25 EP EP08748081A patent/EP2139886A4/en not_active Withdrawn
- 2008-03-25 AR ARP080101216A patent/AR065845A1/es unknown
- 2008-03-25 MX MX2009010193A patent/MX2009010193A/es active IP Right Grant
- 2008-03-25 WO PCT/CA2008/000569 patent/WO2008116308A1/en not_active Ceased
- 2008-03-25 JP JP2010500037A patent/JP2010521527A/ja active Pending
- 2008-03-25 NZ NZ580618A patent/NZ580618A/en not_active IP Right Cessation
- 2008-03-25 CA CA002681771A patent/CA2681771A1/en not_active Abandoned
- 2008-03-25 CN CN200880017025A patent/CN101679397A/zh active Pending
- 2008-03-25 AU AU2008232269A patent/AU2008232269A1/en not_active Abandoned
-
2009
- 2009-09-23 IL IL201142A patent/IL201142A/en not_active IP Right Cessation
- 2009-10-23 ZA ZA2009/07458A patent/ZA200907458B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TW200902003A (en) | 2009-01-16 |
| WO2008116308A1 (en) | 2008-10-02 |
| NZ580618A (en) | 2012-07-27 |
| IL201142A (en) | 2013-12-31 |
| TWI417099B (zh) | 2013-12-01 |
| EP2139886A1 (en) | 2010-01-06 |
| JP2010521527A (ja) | 2010-06-24 |
| IL201142A0 (en) | 2010-05-17 |
| MX2009010193A (es) | 2009-12-15 |
| CL2008000838A1 (es) | 2008-10-10 |
| CA2681771A1 (en) | 2008-10-02 |
| CN101679397A (zh) | 2010-03-24 |
| AU2008232269A1 (en) | 2008-10-02 |
| US20080234237A1 (en) | 2008-09-25 |
| EP2139886A4 (en) | 2011-03-30 |
| ZA200907458B (en) | 2011-01-26 |
| US8173813B2 (en) | 2012-05-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |