AR064786A1 - Compuestos complejos de hidrato de carbono y hierro, procedimientos para su elaboracion, medicamentos que los contienen y su uso - Google Patents

Compuestos complejos de hidrato de carbono y hierro, procedimientos para su elaboracion, medicamentos que los contienen y su uso

Info

Publication number
AR064786A1
AR064786A1 ARP080100071A ARP080100071A AR064786A1 AR 064786 A1 AR064786 A1 AR 064786A1 AR P080100071 A ARP080100071 A AR P080100071A AR P080100071 A ARP080100071 A AR P080100071A AR 064786 A1 AR064786 A1 AR 064786A1
Authority
AR
Argentina
Prior art keywords
iron
carbohydrate
complex compound
procedures
development
Prior art date
Application number
ARP080100071A
Other languages
English (en)
Inventor
Peter Geisser
Stefan Reim
Original Assignee
Vifor Int Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38441703&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR064786(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vifor Int Ag filed Critical Vifor Int Ag
Publication of AR064786A1 publication Critical patent/AR064786A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B31/00—Preparation of derivatives of starch
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00—Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0021—Dextran, i.e. (alpha-1,4)-D-glucan; Derivatives thereof, e.g. Sephadex, i.e. crosslinked dextran

Abstract

Es objeto también un procedimiento preferido para elaborar un compuesto complejo de hidrato de carbono y hierro y su uso para tratar anemias sideroprivas. Reivindicacion 1: Un compuesto complejo de hidrato de carbono y hierro, caracterizado porque la fraccion de hierro (II) en relacion con la cantidad total de hierro en el compuesto complejo es por lo menos del 2% en peso. Reivindicacion 3: El compuesto complejo de hidrato de carbono y hierro de conformidad con la reivindicacion 1 o 2, caracterizado además porque la fraccion del hidrato de carbono, en relacion con el compuesto complejo de hidrato de carbono y hierro, es del 10 al 80% en peso. Reivindicacion 8: El compuesto complejo de hidrato de carbono y hierro de conformidad con cualquiera de las reivindicaciones 1 a 7, caracterizado además porque se selecciona el hidrato de carbono del grupo que consiste en hidratos de carbono naturales o derivados sintéticos de hidrato de carbono, tales como almidon, almidones hidrolizados, dextrinas (en particular maltodextrina, jarabe de maltosa, jarabe de glucosa), ciclodextrinas, dextranos, sacáridos.
ARP080100071A 2007-01-19 2008-01-08 Compuestos complejos de hidrato de carbono y hierro, procedimientos para su elaboracion, medicamentos que los contienen y su uso AR064786A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP07100803A EP1947120A1 (de) 2007-01-19 2007-01-19 Eisen-Kohlenhydrat-Komplex-Verbindungen

Publications (1)

Publication Number Publication Date
AR064786A1 true AR064786A1 (es) 2009-04-22

Family

ID=38441703

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP080100071A AR064786A1 (es) 2007-01-19 2008-01-08 Compuestos complejos de hidrato de carbono y hierro, procedimientos para su elaboracion, medicamentos que los contienen y su uso

Country Status (25)

Country Link
US (1) US8263564B2 (es)
EP (2) EP1947120A1 (es)
JP (1) JP5225289B2 (es)
KR (1) KR101200992B1 (es)
CN (1) CN101589064B (es)
AR (1) AR064786A1 (es)
AU (1) AU2008206969B2 (es)
BR (1) BRPI0807037A2 (es)
CA (1) CA2675117C (es)
CL (1) CL2008000140A1 (es)
ES (1) ES2732290T5 (es)
GT (1) GT200900204A (es)
HK (1) HK1135417A1 (es)
IL (1) IL199726A (es)
MA (1) MA31113B1 (es)
MX (1) MX2009007695A (es)
MY (1) MY148299A (es)
NZ (1) NZ578457A (es)
PE (1) PE20090187A1 (es)
RU (1) RU2423122C2 (es)
SA (1) SA08290017B1 (es)
TN (1) TN2009000303A1 (es)
TW (1) TWI388330B (es)
WO (1) WO2008087135A1 (es)
ZA (1) ZA200905738B (es)

Families Citing this family (16)

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Publication number Priority date Publication date Assignee Title
US20120214986A1 (en) * 2009-11-04 2012-08-23 Symed Labs Limited Process for the preparation of iron (iii) carboxymaltose complex
CN101967205B (zh) * 2010-10-12 2013-04-17 滨州学院 一种β-葡聚糖铁复合物及其制备方法
CN106176808A (zh) * 2010-10-19 2016-12-07 长春纳米生技公司 金属离子纳米簇组合物
WO2012104204A1 (en) 2011-01-31 2012-08-09 Vifor (International) Ag Iron-carbohydrate complex compounds for the intravenous therapy of malaria
WO2013056085A1 (en) 2011-10-13 2013-04-18 Vidasym, Inc. Iron-fiber composition, preparation and uses thereof
WO2014065890A1 (en) * 2012-10-25 2014-05-01 Otc Nutrition Llc Fast dissolving solid calcium mineral supplement compositions and process of making
AU2013366649B2 (en) * 2012-12-21 2018-02-01 Vifor (International) Ag Fe(III) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemia
CN105007759B (zh) * 2013-03-08 2018-11-20 上海礼邦医药科技有限公司 金属离子-功能性纤维组分络合物组合物、其制备及用途
WO2016194000A1 (en) * 2015-05-29 2016-12-08 Sun Pharmaceutical Industries Ltd. Composition of iron sucrose and process for its preparation
US10258647B2 (en) 2015-09-01 2019-04-16 Particle Dynamics International, Llc Iron-polysaccharide complexes and methods for the preparation thereof
RU2625739C1 (ru) * 2016-09-28 2017-07-18 Общество с ограниченной ответственностью Научно-производственное предприятие "Эксорб" Фармакологическая композиция на основе соединений железа
LT3930686T (lt) 2019-02-28 2023-10-10 Renibus Therapeutics, Inc. Naujos geležies kompozicijos ir jų gamybos bei naudojimo būdai
CN112156109A (zh) * 2020-09-29 2021-01-01 神奈纳米医药技术(珠海)有限公司 氢氧化铁-糖络合物的制备方法及其应用
RU2763135C1 (ru) * 2021-04-23 2021-12-27 Виктор Павлович Ремез Фармакологическая композиция для лечения железодефицитной анемии
WO2023036917A1 (en) * 2021-09-10 2023-03-16 The European Atomic Energy Community (Euratom), Represented By The European Commission Embedded product for the transportation, storage and/or handling of lanthanides or actinides and method of manufacturing
WO2023041957A1 (en) * 2021-09-16 2023-03-23 Virchow Biotech Private Limited Efficient process for the synthesis of iron (iii) carbohydrate complexes

Family Cites Families (15)

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DE1617463A1 (de) * 1965-11-20 1971-04-08 Bayer Ag Verfahren zur Herstellung von injizierbaren kolloidalen Eisenzubereitungen
DE3026868C2 (de) * 1980-07-16 1986-03-13 Laboratorien Hausmann AG, St. Gallen Verfahren zur Herstellung von Eisen(III)hydroxid-Dextran-Komplexen und sie enthaltende pharmazeutische sterile wäßrige Lösung
CA1319612C (en) 1987-07-02 1993-06-29 Haile Mehansho Iron-calcium mineral supplements with enhanced bioavailability
US4786518A (en) 1987-07-02 1988-11-22 The Procter & Gamble Company Iron mineral supplements
DE3844065A1 (de) † 1988-12-28 1990-07-05 Orgaplan Gmbh Glycosidische eisen-ii- und eisen-iii-komplexzubereitungen und ihre verwendung
DK172860B1 (da) * 1998-03-25 1999-08-16 Pharmacosmos Holding As Jerndextranforbindelse til anvendelse som komponent i et terapeutisk middel til forebyggelse af eller behandling af jernman
US6461651B1 (en) * 2000-09-26 2002-10-08 General Mills, Inc. Sodium-free iron complex for food fortification
RU2198665C1 (ru) * 2001-12-27 2003-02-20 Общество с ограниченной ответственностью Фирма "А-БИО" Способ получения железосодержащего лекарственного средства
DE10249552A1 (de) * 2002-10-23 2004-05-13 Vifor (International) Ag Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel
US7964568B2 (en) * 2003-05-30 2011-06-21 Chromaceutical Advanced Technologies, Inc. Synthesis of high molecular weight iron-saccharidic complexes
WO2005116046A1 (de) * 2004-05-24 2005-12-08 Cilag Ag Verfahren zur herstellung von eisensaccharosekomplex
WO2006006897A1 (en) 2004-07-09 2006-01-19 Telefonaktiebolaget Lm Ericsson (Publ) Method and arrangement for providing different services in a multimedia communication system
CN1739531A (zh) * 2005-09-12 2006-03-01 南京生命能科技开发有限公司 一种治疗缺铁性贫血的蔗糖铁注射液及其制备方法
CN101215338B (zh) * 2007-01-05 2010-09-15 庄茅 异麦芽低聚糖铁及其制备方法
CN101390923A (zh) * 2007-09-21 2009-03-25 韩泳平 一种红景天多糖铁复方制剂的制备及应用

Also Published As

Publication number Publication date
BRPI0807037A2 (pt) 2014-04-22
CN101589064A (zh) 2009-11-25
TWI388330B (zh) 2013-03-11
US20100035830A1 (en) 2010-02-11
SA08290017B1 (ar) 2011-09-13
IL199726A (en) 2014-05-28
CL2008000140A1 (es) 2008-05-16
CA2675117C (en) 2014-03-25
ES2732290T5 (es) 2022-06-07
HK1135417A1 (en) 2010-06-04
KR20090102861A (ko) 2009-09-30
EP2111416B2 (de) 2022-03-30
TW200835511A (en) 2008-09-01
AU2008206969B2 (en) 2012-12-06
TN2009000303A1 (en) 2010-12-31
IL199726A0 (en) 2010-04-15
PE20090187A1 (es) 2009-03-15
JP5225289B2 (ja) 2013-07-03
MX2009007695A (es) 2009-07-29
GT200900204A (es) 2010-07-22
EP2111416A1 (de) 2009-10-28
EP1947120A1 (de) 2008-07-23
CN101589064B (zh) 2014-01-29
CA2675117A1 (en) 2008-07-24
AU2008206969A1 (en) 2008-07-24
RU2009131464A (ru) 2011-03-10
RU2423122C2 (ru) 2011-07-10
ES2732290T3 (es) 2019-11-21
NZ578457A (en) 2011-08-26
KR101200992B1 (ko) 2012-11-13
MA31113B1 (fr) 2010-01-04
MY148299A (en) 2013-03-29
US8263564B2 (en) 2012-09-11
EP2111416B1 (de) 2019-05-15
WO2008087135A1 (de) 2008-07-24
JP2010516828A (ja) 2010-05-20
ZA200905738B (en) 2010-05-26

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