AR064726A1 - Inhibidores de rho quinasa - Google Patents

Inhibidores de rho quinasa

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Publication number
AR064726A1
AR064726A1 ARP080100007A ARP080100007A AR064726A1 AR 064726 A1 AR064726 A1 AR 064726A1 AR P080100007 A ARP080100007 A AR P080100007A AR P080100007 A ARP080100007 A AR P080100007A AR 064726 A1 AR064726 A1 AR 064726A1
Authority
AR
Argentina
Prior art keywords
alkyl
ring
independently selected
attached
benzyl
Prior art date
Application number
ARP080100007A
Other languages
English (en)
Spanish (es)
Inventor
Wang Mao
Richard Hickey
Xinag Li
Robert Sibley
John Robert Snow
Ronald John Sorcek
Frank Wu
Erick Richard YOUNG
Daniel Richard Marshall
Tina Morwick
Georg Dahmann
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of AR064726A1 publication Critical patent/AR064726A1/es

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    • C07C275/38—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by doubly-bound oxygen atoms
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    • C07C275/42—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
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    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
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    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

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ARP080100007A 2007-01-03 2008-01-02 Inhibidores de rho quinasa AR064726A1 (es)

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US10787450B2 (en) 2016-07-07 2020-09-29 Bristol-Myers Squibb Company Spiro-fused cyclic ureas as inhibitors of rock
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KR102644889B1 (ko) 2017-07-12 2024-03-06 브리스톨-마이어스 스큅 컴퍼니 Rock 억제제로서의 스피로헵타닐 히단토인
TW201908293A (zh) 2017-07-12 2019-03-01 美商必治妥美雅史谷比公司 作為rock抑制劑之5員及雙環雜環醯胺
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