AR060085A1 - Vehiculo bioadhesivo de liberacion lenta en mucosas para administrar principios activos - Google Patents

Vehiculo bioadhesivo de liberacion lenta en mucosas para administrar principios activos

Info

Publication number
AR060085A1
AR060085A1 ARP070101207A ARP070101207A AR060085A1 AR 060085 A1 AR060085 A1 AR 060085A1 AR P070101207 A ARP070101207 A AR P070101207A AR P070101207 A ARP070101207 A AR P070101207A AR 060085 A1 AR060085 A1 AR 060085A1
Authority
AR
Argentina
Prior art keywords
release
bioadhesive
slow
active ingredient
vehicle
Prior art date
Application number
ARP070101207A
Other languages
English (en)
Original Assignee
Bioalliance Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioalliance Pharma filed Critical Bioalliance Pharma
Publication of AR060085A1 publication Critical patent/AR060085A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2063—Proteins, e.g. gelatin

Abstract

Un vehículo bioadhesivo de liberacion lenta en mucosas que comprende un principio activo y que carece de almidon, lactosa, que puede liberar el principio activo para una duracion mayor de 20 horas. Este vehículo bioadhesivo contiene un diluyente, un alquilsulfato de metal alcalino, un agente aglutinante, al menos un polímero bioadhesivo y al menos un polímero de liberacion prolongada, al igual que un método para su preparacion. Reivindicacion 8: El vehículo bioadhesivo de liberacion lenta en mucosas de acuerdo con cualquiera de las reivindicaciones 1 a 7, en el cual dicho al menos un principio activo es antiviral seleccionado de aciclovir, valaciclovir, zidovudina, ganciclovor, pencidovir, famciclovir, foscarnet, rivavirina, lamiduvina, amantadina, IFNalfa, cidofovir o ramantadina. Reivindicacion 12: El vehículo bioadhesivo de liberacion lenta en mucosas de acuerdo con cualquiera de las reivindicaciones 1 a 7, en el cual dicho al menos un principio activo es fentanilo o citrato de fentanilo o sulfentanilo y se encuentra presente en una cantidad de 50 a 1600 micro g en dicho vehículo.
ARP070101207A 2006-03-24 2007-03-23 Vehiculo bioadhesivo de liberacion lenta en mucosas para administrar principios activos AR060085A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06290480A EP1837020A1 (en) 2006-03-24 2006-03-24 Mucosal bioadhesive slow release carrier for delivering active principles

Publications (1)

Publication Number Publication Date
AR060085A1 true AR060085A1 (es) 2008-05-21

Family

ID=36889131

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP070101207A AR060085A1 (es) 2006-03-24 2007-03-23 Vehiculo bioadhesivo de liberacion lenta en mucosas para administrar principios activos

Country Status (27)

Country Link
US (5) US20090169511A1 (es)
EP (3) EP1837020A1 (es)
JP (1) JP5242548B2 (es)
KR (1) KR101335185B1 (es)
CN (1) CN101410092B (es)
AR (1) AR060085A1 (es)
AT (1) ATE446743T1 (es)
AU (1) AU2007231029B2 (es)
BR (1) BRPI0709057C1 (es)
CA (1) CA2647123C (es)
CY (1) CY1109723T1 (es)
DE (1) DE602007002996D1 (es)
DK (1) DK1998750T3 (es)
ES (1) ES2335712T3 (es)
HK (1) HK1121692A1 (es)
HR (1) HRP20100039T1 (es)
IL (1) IL193987A (es)
ME (1) ME01180B (es)
MX (1) MX2008012186A (es)
MY (1) MY150072A (es)
PL (1) PL1998750T3 (es)
PT (1) PT1998750E (es)
RS (1) RS51342B (es)
RU (1) RU2420267C2 (es)
SI (1) SI1998750T1 (es)
WO (1) WO2007110778A2 (es)
ZA (1) ZA200807883B (es)

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EP1837020A1 (en) 2006-03-24 2007-09-26 Bioalliance Pharma Mucosal bioadhesive slow release carrier for delivering active principles
EP2165706A1 (en) * 2008-09-18 2010-03-24 BioAlliance Pharma Treating Inflammatory Pain in Mucosa of the Oral Cavity Using Mucosal Prolonged Release Bioadhesive Therapeutic Carriers.
EP2335690A1 (en) 2009-12-09 2011-06-22 BioAlliance Pharma Mucoadhesive buccal tablets for the treatment of orofacial herpes
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US8592434B2 (en) * 2009-12-09 2013-11-26 Bioalliance Pharma Sa Mucoadhesive buccal tablets for the treatment of orofacial herpes
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EP2814467B1 (en) * 2012-02-19 2020-03-11 Quest Products, LLC Alkalized acacia gum adhesive for oral adhering discs
WO2016176396A1 (en) * 2015-04-29 2016-11-03 Foresight Biotherapeutics, Inc. Therapeutic combinations of antiviral and anti-inflammatory therapies
RU2636185C1 (ru) * 2016-08-03 2017-11-21 Федеральное государственное бюджетное образовательное учреждение высшего образования "Ставропольский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО СтГМУ Минздрава России) Способ лечения хронического генерализованного катарального гингивита в стадии обострения
RU2636173C1 (ru) * 2016-08-03 2017-11-21 Федеральное государственное бюджетное образовательное учреждение высшего образования "Ставропольский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО СтГМУ Минздрава России) Способ лечения хронического генерализованного пародонтита средней степени тяжести в стадии обострения
BR102018008324A2 (pt) * 2018-04-25 2019-11-05 Laboratorios Ferring Ltda composição farmacêutica de uso tópico e processo de fabricação de composição farmacêutica de uso tópico
BR112020022260A2 (pt) * 2018-04-30 2021-02-23 Perfect Day, Inc polímeros da proteína do leite recombinantes
WO2020150460A1 (en) * 2019-01-18 2020-07-23 Milne Iii Donald A Micronized aspirin formulation
CN111803468B (zh) * 2020-06-23 2022-12-23 黑龙江天龙药业有限公司 一种靶向、缓释、成膜抑制病毒、细菌的鼻腔喷膜剂及其制备方法
CN115463102B (zh) * 2022-09-26 2023-11-24 湖北科益药业股份有限公司 一种阿昔洛韦片剂及其制备方法

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Also Published As

Publication number Publication date
BRPI0709057B8 (pt) 2021-02-23
DE602007002996D1 (de) 2009-12-10
IL193987A (en) 2012-06-28
SI1998750T1 (sl) 2010-02-26
RU2420267C2 (ru) 2011-06-10
EP1998750A2 (en) 2008-12-10
ES2335712T3 (es) 2010-03-31
HK1121692A1 (en) 2009-04-30
US8211466B2 (en) 2012-07-03
MX2008012186A (es) 2009-01-16
US20120329817A1 (en) 2012-12-27
MY150072A (en) 2013-11-29
US20090169511A1 (en) 2009-07-02
US20100266667A1 (en) 2010-10-21
RU2008139869A (ru) 2010-04-27
ZA200807883B (en) 2011-02-23
JP2009531411A (ja) 2009-09-03
CA2647123A1 (en) 2007-10-04
WO2007110778A2 (en) 2007-10-04
WO2007110778A3 (en) 2008-04-24
CN101410092B (zh) 2012-05-23
CA2647123C (en) 2013-08-06
US8791127B2 (en) 2014-07-29
KR101335185B1 (ko) 2013-12-02
HRP20100039T1 (hr) 2010-02-28
US20120326350A1 (en) 2012-12-27
PL1998750T3 (pl) 2010-03-31
IL193987A0 (en) 2009-09-22
BRPI0709057A2 (pt) 2011-06-28
CN101410092A (zh) 2009-04-15
US8747896B2 (en) 2014-06-10
EP1998750B1 (en) 2009-10-28
DK1998750T3 (da) 2010-01-25
JP5242548B2 (ja) 2013-07-24
PT1998750E (pt) 2010-01-08
CY1109723T1 (el) 2014-08-13
US20130303556A1 (en) 2013-11-14
EP1837020A1 (en) 2007-09-26
ME01180B (me) 2013-03-20
AU2007231029A1 (en) 2007-10-04
BRPI0709057C1 (pt) 2021-05-25
EP2216017A1 (en) 2010-08-11
KR20090010958A (ko) 2009-01-30
ATE446743T1 (de) 2009-11-15
AU2007231029B2 (en) 2012-02-02
RS51342B (en) 2011-02-28
BRPI0709057B1 (pt) 2020-06-30

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