AR059597A1 - Derivados de aza-tia-benzo-azuleno - Google Patents
Derivados de aza-tia-benzo-azulenoInfo
- Publication number
- AR059597A1 AR059597A1 ARP070100731A ARP070100731A AR059597A1 AR 059597 A1 AR059597 A1 AR 059597A1 AR P070100731 A ARP070100731 A AR P070100731A AR P070100731 A ARP070100731 A AR P070100731A AR 059597 A1 AR059597 A1 AR 059597A1
- Authority
- AR
- Argentina
- Prior art keywords
- alkyl
- amino
- halo
- alkenyl
- alkoxy
- Prior art date
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 10
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 7
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 4
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 150000002367 halogens Chemical class 0.000 abstract 3
- 229910052757 nitrogen Inorganic materials 0.000 abstract 3
- 125000004001 thioalkyl group Chemical group 0.000 abstract 3
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 2
- 125000004890 (C1-C6) alkylamino group Chemical group 0.000 abstract 2
- 125000006619 (C1-C6) dialkylamino group Chemical group 0.000 abstract 2
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 abstract 2
- 206010003246 arthritis Diseases 0.000 abstract 2
- 125000006254 cycloalkyl carbonyl group Chemical group 0.000 abstract 2
- 125000000262 haloalkenyl group Chemical group 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- 125000004454 (C1-C6) alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000004916 (C1-C6) alkylcarbonyl group Chemical group 0.000 abstract 1
- 125000003320 C2-C6 alkenyloxy group Chemical group 0.000 abstract 1
- 125000003601 C2-C6 alkynyl group Chemical group 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 208000027418 Wounds and injury Diseases 0.000 abstract 1
- 208000038016 acute inflammation Diseases 0.000 abstract 1
- 230000006022 acute inflammation Effects 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000006620 amino-(C1-C6) alkyl group Chemical group 0.000 abstract 1
- 230000002917 arthritic effect Effects 0.000 abstract 1
- 125000001769 aryl amino group Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 230000006378 damage Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
- 125000005291 haloalkenyloxy group Chemical group 0.000 abstract 1
- -1 hydroxy C1-6 alkyl Chemical group 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 208000014674 injury Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06003702 | 2006-02-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR059597A1 true AR059597A1 (es) | 2008-04-16 |
Family
ID=36282923
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP070100731A AR059597A1 (es) | 2006-02-23 | 2007-02-21 | Derivados de aza-tia-benzo-azuleno |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US8258128B2 (https=) |
| EP (1) | EP1989209B1 (https=) |
| JP (1) | JP5135233B2 (https=) |
| KR (1) | KR20080106525A (https=) |
| CN (1) | CN101389633B (https=) |
| AR (1) | AR059597A1 (https=) |
| AU (1) | AU2007218166B9 (https=) |
| BR (1) | BRPI0708251A2 (https=) |
| CA (1) | CA2640488C (https=) |
| ES (1) | ES2540089T3 (https=) |
| IL (1) | IL192928A0 (https=) |
| MX (1) | MX2008010834A (https=) |
| NO (1) | NO20083558L (https=) |
| NZ (1) | NZ569551A (https=) |
| RU (1) | RU2430921C2 (https=) |
| TW (1) | TW200808810A (https=) |
| WO (1) | WO2007096150A2 (https=) |
| ZA (1) | ZA200805331B (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200808810A (en) | 2006-02-23 | 2008-02-16 | Novartis Ag | Organic compounds |
| IT1391792B1 (it) * | 2008-11-21 | 2012-01-27 | Forem Pharma S R L | Composizione per un integratore naturale alimentare, particolarmente per favorire la fisiologica funzionalita' delle cartilagini. |
| CN105727249A (zh) * | 2016-03-24 | 2016-07-06 | 河南牧业经济学院 | 治疗猫、犬关节病症的外用膏剂及其制备方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2128029B1 (https=) * | 1971-03-01 | 1974-08-02 | Roussel Uclaf | |
| BE791902A (fr) * | 1971-11-26 | 1973-05-24 | Wander Ag Dr A | Nouveaux derives de la thieno (3,2-c) (1)benzazepine, leur preparation et leur application comme medicaments |
| DE2918778A1 (de) * | 1979-05-10 | 1980-11-20 | Basf Ag | 6-substituierte 11-alkylen-morphantridine |
| DE2918832A1 (de) * | 1979-05-10 | 1980-11-20 | Basf Ag | 5,6-dihydro-11-alkylen-morphantridin- 6-one |
| HU195800B (en) * | 1983-10-13 | 1988-07-28 | Sandoz Ltd | Process for producing 4h-benzo/4,5/cylopenta/1,2-b/ thiofene derivatives and pharmaceutical compositions containing them |
| DE3524744A1 (de) * | 1985-07-11 | 1987-01-15 | Basf Ag | 4-substituierte 10-cyanmethylen-thieno (4,3-e)-benzo-azepine |
| JP2766266B2 (ja) * | 1988-06-20 | 1998-06-18 | 協和醗酵工業株式会社 | ピリジン誘導体およびその中間体 |
| SE9901530D0 (sv) * | 1999-04-28 | 1999-04-28 | Astra Pharma Prod | Novel compounds |
| SE9901901D0 (sv) * | 1999-05-26 | 1999-05-26 | Astra Ab | Compounds |
| TW200808810A (en) | 2006-02-23 | 2008-02-16 | Novartis Ag | Organic compounds |
-
2007
- 2007-02-16 TW TW096106330A patent/TW200808810A/zh unknown
- 2007-02-21 MX MX2008010834A patent/MX2008010834A/es active IP Right Grant
- 2007-02-21 US US12/224,734 patent/US8258128B2/en not_active Expired - Fee Related
- 2007-02-21 KR KR1020087020597A patent/KR20080106525A/ko not_active Withdrawn
- 2007-02-21 AU AU2007218166A patent/AU2007218166B9/en not_active Ceased
- 2007-02-21 ES ES07722883.1T patent/ES2540089T3/es active Active
- 2007-02-21 NZ NZ569551A patent/NZ569551A/en not_active IP Right Cessation
- 2007-02-21 JP JP2008555694A patent/JP5135233B2/ja not_active Expired - Fee Related
- 2007-02-21 RU RU2008137533/04A patent/RU2430921C2/ru not_active IP Right Cessation
- 2007-02-21 CN CN2007800064548A patent/CN101389633B/zh not_active Expired - Fee Related
- 2007-02-21 WO PCT/EP2007/001507 patent/WO2007096150A2/en not_active Ceased
- 2007-02-21 EP EP07722883.1A patent/EP1989209B1/en not_active Not-in-force
- 2007-02-21 CA CA2640488A patent/CA2640488C/en not_active Expired - Fee Related
- 2007-02-21 AR ARP070100731A patent/AR059597A1/es not_active Application Discontinuation
- 2007-02-21 BR BRPI0708251-7A patent/BRPI0708251A2/pt not_active IP Right Cessation
-
2008
- 2008-06-19 ZA ZA200805331A patent/ZA200805331B/xx unknown
- 2008-07-21 IL IL192928A patent/IL192928A0/en unknown
- 2008-08-15 NO NO20083558A patent/NO20083558L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2007218166B9 (en) | 2011-02-10 |
| ZA200805331B (en) | 2009-10-28 |
| IL192928A0 (en) | 2009-02-11 |
| TW200808810A (en) | 2008-02-16 |
| CN101389633B (zh) | 2011-08-24 |
| RU2008137533A (ru) | 2010-03-27 |
| ES2540089T3 (es) | 2015-07-08 |
| KR20080106525A (ko) | 2008-12-08 |
| AU2007218166A1 (en) | 2007-08-30 |
| RU2430921C2 (ru) | 2011-10-10 |
| EP1989209B1 (en) | 2015-03-25 |
| EP1989209A2 (en) | 2008-11-12 |
| US8258128B2 (en) | 2012-09-04 |
| NO20083558L (no) | 2008-09-10 |
| AU2007218166B2 (en) | 2010-11-18 |
| CA2640488C (en) | 2016-04-26 |
| CA2640488A1 (en) | 2007-08-30 |
| JP2009527518A (ja) | 2009-07-30 |
| WO2007096150A2 (en) | 2007-08-30 |
| MX2008010834A (es) | 2008-11-14 |
| JP5135233B2 (ja) | 2013-02-06 |
| US20090131408A1 (en) | 2009-05-21 |
| WO2007096150A3 (en) | 2007-10-25 |
| BRPI0708251A2 (pt) | 2011-05-24 |
| CN101389633A (zh) | 2009-03-18 |
| NZ569551A (en) | 2011-06-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR069490A1 (es) | Agonistas de los receptores de glucocorticoides | |
| ATE517882T1 (de) | Chinolinderivate | |
| AR047098A1 (es) | Derivados de arilanilina como agonistas del receptor adrenergico beta2 | |
| EA201101672A1 (ru) | Замещенные производные аминомасляной кислоты в качестве ингибиторов неприлизина | |
| AR038686A1 (es) | Formulaciones de derivados de androstano y agonistas del adrenoreceptor beta 2 antiinflamatorios | |
| AR046297A1 (es) | Inhibidores de la dpp - iv metodos para prepararlos y composiciones farmaceuticas que los contienen como agente activo | |
| AR045470A1 (es) | Derivados de acido fenoxiacetico | |
| EA201101671A1 (ru) | Замещенные производные аминопропионовой кислоты в качестве ингибиторов неприлизина | |
| EA200601350A1 (ru) | Азотсодержащие гетероциклические производные и их фармацевтические применения | |
| AR063331A1 (es) | Derivados de biaril eter urea y composiciones farmaceuticas | |
| AR042956A1 (es) | Inhibidores de girasa y usos de los mismos | |
| CY1109490T1 (el) | Τρικυκλικοι τροποποιητες πυρηνικων υποδοχεων στεροειδων ορμονων | |
| EA200970461A1 (ru) | ЗАМЕЩЕННЫЕ ПРОИЗВОДНЫЕ 3-ИЗОБУТИЛ-9,10-ДИМЕТОКСИ-1,3,4,6,7,11b-ГЕКСАГИДРО-2Н-ПИРИДО[2,1-a]ИЗОХИНОЛИН-2-ОЛА И СВЯЗАННЫЕ С НИМИ СПОСОБЫ | |
| DOP2006000084A (es) | Compuestos sulfoximino-macrociclicos y sus sales, composiciones farmaceuticas que comprenden dichos compuestos, metodos de preparacion y usos de los mismos | |
| AR053092A1 (es) | Compuestos derivados de acido fenoxiacetico y compuestos intermediarios de sintesis | |
| AR058073A1 (es) | Derivados de imidazol 5-il-pirimidina, procesos de obtencion, composiciones farmaceuticas y usos | |
| RU2013124812A (ru) | Зонд, визуализирующий белок тау | |
| MA30315B1 (fr) | Derives de 1,2,4,5-tetrahydro-3h-benzazepines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent | |
| AR058885A1 (es) | Compuestos de piperidina 3,5-sustituidos | |
| MX376743B (es) | Síntesis de lactonas de ácido resorcílico útiles como agentes terapéuticos | |
| AR055017A1 (es) | Derivados de amida, un proceso para su preparacion, composicion farmaceutica y uso del compuesto para la fabricacion de farmacos | |
| AR055303A1 (es) | Derivados de triazol sustituidos como antagonistas de oxitocina, composicion farmaceutica y uso del compuesto para preparar un medicamento | |
| BR0317487A (pt) | O r-isÈmero de compostos de aminoácido beta como derivados de antagonistas de receptores de integrina | |
| AR052938A1 (es) | Compuestos de n-sulfonilaminofeniletil-2-fenoxiacetamida sustituidos, composiciones farmaceuticas que los comprenden y su uso en la preparacion de medicamentos para el tratamiento de enfermedades mediadas por el receptor vr1 | |
| AR067454A1 (es) | Derivados de indano- amina, su preparacion y uso como medicamentos |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |