AR044843A1 - Mejoras en la produccion de virus - Google Patents

Mejoras en la produccion de virus

Info

Publication number
AR044843A1
AR044843A1 ARP040102154A ARP040102154A AR044843A1 AR 044843 A1 AR044843 A1 AR 044843A1 AR P040102154 A ARP040102154 A AR P040102154A AR P040102154 A ARP040102154 A AR P040102154A AR 044843 A1 AR044843 A1 AR 044843A1
Authority
AR
Argentina
Prior art keywords
virus
virus production
residues
allantoic fluid
viruses
Prior art date
Application number
ARP040102154A
Other languages
English (en)
Original Assignee
Microbix Biosystems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33545338&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR044843(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Microbix Biosystems Inc filed Critical Microbix Biosystems Inc
Publication of AR044843A1 publication Critical patent/AR044843A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16051—Methods of production or purification of viral material

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Pulmonology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Un proceso mejorado para recuperar virus de fluido alantoico de embriones de aves infectados con virus. Los virus asociados con residuos granulares y fibrosos en el fluido alantoico se pueden disociar de los residuos y ser recuperados, disminuyendo así el rendimiento viral. La disociación se puede lograr sometiendo al complejo virus-residuos a condiciones de concentraciones elevadas de sal, por ejemplo 0,5 M o más.
ARP040102154A 2003-06-20 2004-06-22 Mejoras en la produccion de virus AR044843A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US47972303P 2003-06-20 2003-06-20
US54078204P 2004-01-30 2004-01-30
US57271804P 2004-05-20 2004-05-20

Publications (1)

Publication Number Publication Date
AR044843A1 true AR044843A1 (es) 2005-10-05

Family

ID=33545338

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP040102154A AR044843A1 (es) 2003-06-20 2004-06-22 Mejoras en la produccion de virus

Country Status (10)

Country Link
US (2) US7270990B2 (es)
EP (1) EP1636352B1 (es)
JP (1) JP4558652B2 (es)
AR (1) AR044843A1 (es)
AT (1) ATE478137T1 (es)
AU (1) AU2004249802B2 (es)
CA (1) CA2503774C (es)
DE (1) DE602004028736D1 (es)
MX (1) MXPA05005306A (es)
WO (1) WO2004113518A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200634145A (en) * 2005-01-25 2006-10-01 Wyeth Res Ireland Ltd Shear protectants in harvest microfiltration
WO2008021493A2 (en) * 2006-08-18 2008-02-21 Huiru Wang A process for identification of molecular mimicry and the uses thereof
RU2011107757A (ru) 2008-08-01 2012-09-10 Гамма Ваксинс Пти Лимитед (Au) Вакцины против гриппа
WO2010079081A1 (en) * 2009-01-07 2010-07-15 Glaxosmithkline Biologicals S.A. Methods for recovering a virus or a viral antigen produced by cell culture
WO2010144797A2 (en) 2009-06-12 2010-12-16 Vaccine Technologies, Incorporated Influenza vaccines with enhanced immunogenicity and uses thereof
US20140079732A1 (en) 2011-01-27 2014-03-20 Gamma Vaccines Pty Limited Combination vaccines
US20150232911A1 (en) * 2013-06-28 2015-08-20 Virocyt, Inc. Processing biological material for flow cytometry evaluation for virus particles
CN105505889A (zh) * 2015-12-24 2016-04-20 华南农业大学 一种禽流感病毒纯化的方法
US10626376B2 (en) 2016-11-14 2020-04-21 St. Jude Children's Research Hospital Method for isolating and purifying adeno-associated virus particles using salt

Family Cites Families (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB660109A (en) 1946-10-01 1951-10-31 American Cyanamid Co Improvements in or relating to the treatment of allantoic fluid containing a propagated virus together with non-viral proteins to obtain the virus in purified and viable from for use in a vaccine
US3105012A (en) 1961-10-19 1963-09-24 Parke Davis & Co Antigen products and means for producing the same
US3316153A (en) 1965-03-29 1967-04-25 Lilly Co Eli Virus purification
AU405949B1 (en) 1966-02-24 1970-09-18 The Australian National University Influenza virus sub-unit vaccine
GB1214135A (en) 1967-02-21 1970-12-02 Wellcome Found Vaccines
US3627873A (en) 1967-06-09 1971-12-14 Arden Wesley Moyer Influenza vaccine with reduced pyrogenicity
US3470067A (en) * 1967-09-19 1969-09-30 Pfizer & Co C Concentration and purification of viruses from particulate magnetic iron oxide-virus complexes
FR1604134A (es) 1967-09-26 1971-07-12
US3547779A (en) * 1968-12-18 1970-12-15 Merck & Co Inc Process for producing purified concentrated influenza virus
US3870598A (en) 1971-04-01 1975-03-11 Alexandra Konstantino Alexeeva Influenzal vaccine for peroral administration and a method of producing same
US4206287A (en) 1972-07-21 1980-06-03 Agence Nationale De Valorisation De La Recherche (Anvar) Vaccines and their preparation
US3919044A (en) * 1973-03-28 1975-11-11 Armour Pharma Processes for concentrating and purifying viruses and viral antigens
US3962421A (en) 1973-06-18 1976-06-08 American Home Products Corporation Method for the disruption of lipid-containing viruses
US3874999A (en) 1973-10-31 1975-04-01 American Cyanamid Co Process for the purification of virus vaccine
US4000257A (en) 1975-12-22 1976-12-28 American Cyanamid Company Process for the purification of influenza virus vaccine
SE420977B (sv) 1976-03-18 1981-11-16 Kabi Ab Forfarande for rening och isolering av hepatitvirus for vaccinframstellning
US4057626A (en) 1976-10-08 1977-11-08 Richardson-Merrell Inc. Process for detoxifying influenza B virus
US4500513A (en) 1979-05-15 1985-02-19 Miles Laboratories, Inc. Influenza vaccine production in liquid cell culture
US4338296A (en) 1979-10-16 1982-07-06 Smithkline-Rit Influenza virus and process of producing a vaccine therefrom
DE3014189A1 (de) 1980-04-14 1981-10-15 Europäisches Laboratorium für Molekularbiologie (EMBL), 6900 Heidelberg Verfahren zur herstellung eines immunogenen membranproteinaggregats von influenza-, parainfluenza- und rhabdo-viren
US4327182A (en) 1981-01-22 1982-04-27 Connaught Laboratories Incorporated Purification of influenza sub-unit vaccine
FR2505657A1 (fr) 1981-05-13 1982-11-19 Pasteur Institut Perfectionnements apportes aux agents de stabilisation de virus vivants pour la preparation de vaccins, et vaccins stabilises contenant lesdits agents de stabilisation
JPS6147186A (ja) * 1984-08-09 1986-03-07 Chemo Sero Therapeut Res Inst インフルエンザウイルスの精製方法
US4783411A (en) 1984-10-22 1988-11-08 Janis Gabliks Influenza-A virus vaccine from fish cell cultures
US4808518A (en) * 1985-02-11 1989-02-28 University Of Tennessee Research Corporation Recovery of cytomegalovirus antigen and use thereof in an assay
US4762939A (en) * 1987-09-30 1988-08-09 Union Carbide Corporation Process for trialkoxysilane/tetraalkoxysilane mixtures from silicon metal and alcohol
US5506129A (en) 1991-05-24 1996-04-09 Evans Medical Limited Virus production
US5762939A (en) 1993-09-13 1998-06-09 Mg-Pmc, Llc Method for producing influenza hemagglutinin multivalent vaccines using baculovirus
SE9500724D0 (sv) 1994-06-23 1995-02-24 Pharmacia Ab Filtrering
FR2723740B1 (fr) 1994-08-16 1996-11-08 Pasteur Merieux Serums Vacc Procede de preparation d'antigenes du virus grippal, antigenes obtenus et leurs applications
US5824536A (en) 1994-08-23 1998-10-20 St. Jude Children's Research Hospital Influenza virus replicated in mammalian cell culture and vaccine production
US5698433A (en) 1994-11-10 1997-12-16 Immuno Ag Method for producing influenza virus and vaccine
US6146873A (en) 1994-11-10 2000-11-14 Baxter Aktiengesellschaft Production of orthomyxoviruses in monkey kidney cells using protein-free media
FR2737730B1 (fr) 1995-08-10 1997-09-05 Pasteur Merieux Serums Vacc Procede de purification de virus par chromatographie
DE19681235D2 (de) 1996-01-05 1999-03-11 Cesa Clean Energy S A Verfahren zur Deaktivierung der HIV und anderer Viren
DE19612967A1 (de) 1996-04-01 1997-10-02 Behringwerke Ag Verfahren zur Vermehrung von Influenzaviren in Zellkultur, sowie die durch das Verfahren erhältlichen Influenzaviren
DE19612966B4 (de) 1996-04-01 2009-12-10 Novartis Vaccines And Diagnostics Gmbh & Co. Kg MDCK-Zellen und Verfahren zur Vermehrung von Influenzaviren
EP0848956A1 (en) 1996-12-17 1998-06-24 Dimminaco Ag/Sa/Ltd. In ovo vaccination against Newcastle Disease
GB9705740D0 (en) 1997-03-20 1997-05-07 Medeva Europ Ltd A method of preservation
TW570803B (en) 1997-04-09 2004-01-11 Duphar Int Res Influenza vaccine
GB9716611D0 (en) 1997-08-07 1997-10-08 Cantab Pharmaceuticals Res Ltd Virus preparations and methods
US6210683B1 (en) 1997-09-05 2001-04-03 Merck & Co., Inc. Stabilizers containing recombinant human serum albumin for live virus vaccines
EP1032269B1 (en) 1997-10-09 2007-08-29 Wellstat Biologics Corporation Treatment of neoplasms with interferon-sensitive, clonal viruses
US7780962B2 (en) 1997-10-09 2010-08-24 Wellstat Biologics Corporation Treatment of neoplasms with RNA viruses
KR100281676B1 (ko) 1997-11-29 2001-04-02 신동권 신규한독감생백신바이러스
GB9804632D0 (en) 1998-03-05 1998-04-29 Cantab Pharma Res Virus preparations and methods
EP0974660A1 (en) 1998-06-19 2000-01-26 Stichting Instituut voor Dierhouderij en Diergezondheid (ID-DLO) Newcastle disease virus infectious clones, vaccines and diagnostic assays
US6579528B1 (en) 1998-08-13 2003-06-17 The University Of Pittsburgh - Of The Commonwealth System Of Higher Education Cold-adapted equine influenza viruses
AT408615B (de) 1998-09-15 2002-01-25 Immuno Ag Neue influenzavirus-impfstoffzusammensetzung
AU4246900A (en) 1999-04-15 2000-11-02 Pro-Virus, Inc. Treatment of neoplasms with viruses
WO2002012289A2 (en) 2000-08-07 2002-02-14 Aventis Pasteur Limited Stabilization of immunogens derived from paramyxoviruses
AU2002223560B2 (en) 2000-09-25 2006-06-29 Polymun Scientific Immunbiologische Forschung Gmbh Live influenza vaccine and method of manufacture
GB0024089D0 (en) 2000-10-02 2000-11-15 Smithkline Beecham Biolog Novel compounds
WO2002067983A1 (en) 2001-02-23 2002-09-06 Glaxosmithkline Biologicals S.A. Novel vaccine
AU2002254558A1 (en) 2001-04-27 2002-11-11 Becton, Dickinson And Company Novel vaccine
US7033813B2 (en) 2001-09-05 2006-04-25 Trevor P Castor Inactivated vaccines for aids and other infectious diseases
MXPA04010603A (es) * 2002-04-30 2004-12-13 Oncolytics Biotech Inc Metodos mejorados de purificacion viral.

Also Published As

Publication number Publication date
ATE478137T1 (de) 2010-09-15
WO2004113518A1 (en) 2004-12-29
CA2503774C (en) 2007-09-25
AU2004249802A1 (en) 2004-12-29
JP4558652B2 (ja) 2010-10-06
AU2004249802B2 (en) 2007-06-28
US20050186223A1 (en) 2005-08-25
EP1636352B1 (en) 2010-08-18
US7270990B2 (en) 2007-09-18
EP1636352A1 (en) 2006-03-22
JP2006511240A (ja) 2006-04-06
CA2503774A1 (en) 2004-12-29
MXPA05005306A (es) 2005-10-26
DE602004028736D1 (de) 2010-09-30
US20090035837A1 (en) 2009-02-05

Similar Documents

Publication Publication Date Title
AR044843A1 (es) Mejoras en la produccion de virus
ATE384785T1 (de) Herstellung von viren, virusisolaten, und impfstoffen
CU22939A3 (es) Proceso para la síntesis de 1,3 dioles
CY1119205T1 (el) Διαδικασια για την απομακρυνση μολυσματικων παραγοντων απο μολυσμενο εδαφος.
ATE531440T1 (de) Luftreiniger-anordnung
PE20030298A1 (es) Filtros de agua y procesos para la utilizacion de los mismos
CA2632253A1 (en) Method of controlling airborne viruses with chlorine dioxide gas
BR112014015370A2 (pt) meio de filtração compreendendo um produto de termólise de um oxicalcogeneto de carbono e um sal metálico, método de remoção de cloramina com este meio de filtração, e método de formação deste meio de filtração
DE60122337D1 (de) Verwendung von taci als antitumormittel
AR037607A1 (es) Procedimiento de recuperacion de un polimero en solucion
NO20075357L (no) Vandige suspensjoner eller dispersjoner av uorganiske pigmenter inneholdende en blanding bestaende av dialdehyder og formaldehydspaltere
KR940005535A (ko) 페놀 타르로부터의 페놀 추출방법
ES2165773B1 (es) Proceso para producir oxido de propileno.
DE50211983D1 (de) Ganischem material
WO2008011187A3 (en) Method for making derivatized guar gum and derivatized guar gum made thereby
MX9304044A (es) Procedimiento para la recuperacion y movilizacion de productos petroliferos altamento viscosos.
BRPI0412835A (pt) processo para preparação de uma solução de alfa-1-antitripsina
ATE320480T1 (de) Von der seebarsch epinephelus coioides derivierte unsterbliche zellinie und ihre verwendungen
ATE526302T1 (de) Verfahren zur aufreinigung von hexafluorpropendimeren
EA200600114A1 (ru) Способ и устройство для очистки воздуха и воды
ES2187075T3 (es) Metodo para producir isoureas.
CY1110007T1 (el) Μεθοδος παρασκευης κρυσταλλων ζονισαμιδης απηλλαγμενων απο 1,2-διχλωροαιθανιο και κρυσταλλοι ζονισαμιδης με πολυ υψηλο βαθμο καθαροτητας
KR101115372B1 (ko) 자연해수로부터 고농도 마그네슘 생산 방법
NO20001137D0 (no) FremgangsmÕte for Õ fjerne natriumsulfat fra en fosfatløsning
RU2008122394A (ru) Способ улучшения проводимости трещины в пространстве между опорами, выполненными из проппанта

Legal Events

Date Code Title Description
FG Grant, registration