AR043986A1 - Procedimiento de preparacion de 4, 10 beta-diacetoxi-2alfa-benzoiloxi-5beta, 20-epoxi-1, 13alfa-dihidroxi-9-oxo-19-norciclopropa (g) tax-11-eno - Google Patents
Procedimiento de preparacion de 4, 10 beta-diacetoxi-2alfa-benzoiloxi-5beta, 20-epoxi-1, 13alfa-dihidroxi-9-oxo-19-norciclopropa (g) tax-11-enoInfo
- Publication number
- AR043986A1 AR043986A1 ARP040101161A ARP040101161A AR043986A1 AR 043986 A1 AR043986 A1 AR 043986A1 AR P040101161 A ARP040101161 A AR P040101161A AR P040101161 A ARP040101161 A AR P040101161A AR 043986 A1 AR043986 A1 AR 043986A1
- Authority
- AR
- Argentina
- Prior art keywords
- radical
- formula
- norciclopropa
- diacetoxi
- benzoiloxi
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epoxy Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Reivindicación 1: procedimiento de preparación del compuesto de fórmula (1), en la cual: Ar representa un radical arilo; R representa un átomo de hidrógeno o un radical acetilo, alcoxiacetilo o alquilo; R1 representa un radical benzoilo o un radical R2-O-CO- en el cual R2 representa un radical alquilo lineal o ramificado C1-8 por un procedimiento que consiste en poner en contacto el compuesto de fórmula (2), en el cual R' es un grupo protector de la función hidroxilo cuando en la fórmula (1) R representa el hidrógeno o uno de los grupos citados para R con una base débil elegida entre los tamices moleculares, luego sucesivamente o previamente, en condensar un precursor de la cadena lateral y, finalmente en desproteger las funciones hidroxilos eventualmente protegidas, caracterizado porque la reacción de ciclopropanación tiene lugar en el sulfolano.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0304613A FR2853651B1 (fr) | 2003-04-14 | 2003-04-14 | Procede de preparation du 4,10 beta-diacetoxy-2 alpha- benzoyloxy-5 beta, 20-epoxy-1, 13 alpha-dihydroxy-9-oxo-19- norcyclopropa[g]tax-11-ene |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR043986A1 true AR043986A1 (es) | 2005-08-17 |
Family
ID=33041834
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP040101161A AR043986A1 (es) | 2003-04-14 | 2004-04-06 | Procedimiento de preparacion de 4, 10 beta-diacetoxi-2alfa-benzoiloxi-5beta, 20-epoxi-1, 13alfa-dihidroxi-9-oxo-19-norciclopropa (g) tax-11-eno |
Country Status (26)
| Country | Link |
|---|---|
| EP (1) | EP1615902B1 (es) |
| JP (1) | JP4664903B2 (es) |
| KR (1) | KR101117512B1 (es) |
| CN (1) | CN1317271C (es) |
| AR (1) | AR043986A1 (es) |
| AT (1) | ATE386733T1 (es) |
| AU (1) | AU2004230302B8 (es) |
| BR (1) | BRPI0409332A (es) |
| CA (1) | CA2522482C (es) |
| CO (1) | CO5700730A2 (es) |
| CY (1) | CY1110375T1 (es) |
| DE (1) | DE602004011917T2 (es) |
| DK (1) | DK1615902T3 (es) |
| ES (1) | ES2302008T3 (es) |
| FR (1) | FR2853651B1 (es) |
| HK (1) | HK1088306A1 (es) |
| IL (1) | IL171318A (es) |
| MX (1) | MXPA05010990A (es) |
| NO (1) | NO331813B1 (es) |
| NZ (1) | NZ543014A (es) |
| PL (1) | PL1615902T3 (es) |
| PT (1) | PT1615902E (es) |
| RU (1) | RU2341520C2 (es) |
| TW (1) | TWI360545B (es) |
| WO (1) | WO2004092151A1 (es) |
| ZA (1) | ZA200508209B (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8791279B2 (en) * | 2010-12-13 | 2014-07-29 | Yung Shin Pharm. Ind. Co., Ltd. | Process for preparing taxoids from baccatin derivatives using lewis acid catalyst |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5814658A (en) * | 1992-12-09 | 1998-09-29 | Rhone-Poulenc Rorer S.A. | Taxoids, their preparation and pharmaceutical compositions containing them |
| IL127599A (en) * | 1994-01-28 | 2004-06-01 | Upjohn Co | Process for preparing isotaxol analogs |
| FR2721023B1 (fr) * | 1994-06-09 | 1996-07-12 | Rhone Poulenc Rorer Sa | Nouveaux Taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent. |
| FR2726272B1 (fr) * | 1994-10-26 | 1996-12-06 | Rhone Poulenc Rorer Sa | Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent |
| FR2732968B1 (fr) * | 1995-04-14 | 1997-05-16 | Rhone Poulenc Rorer Sa | Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent |
-
2003
- 2003-04-14 FR FR0304613A patent/FR2853651B1/fr not_active Expired - Fee Related
-
2004
- 2004-04-06 AR ARP040101161A patent/AR043986A1/es unknown
- 2004-04-13 ES ES04742484T patent/ES2302008T3/es not_active Expired - Lifetime
- 2004-04-13 CA CA2522482A patent/CA2522482C/fr not_active Expired - Fee Related
- 2004-04-13 RU RU2005135137/04A patent/RU2341520C2/ru not_active IP Right Cessation
- 2004-04-13 EP EP04742484A patent/EP1615902B1/fr not_active Expired - Lifetime
- 2004-04-13 PL PL04742484T patent/PL1615902T3/pl unknown
- 2004-04-13 AT AT04742484T patent/ATE386733T1/de active
- 2004-04-13 DK DK04742484T patent/DK1615902T3/da active
- 2004-04-13 TW TW093110164A patent/TWI360545B/zh not_active IP Right Cessation
- 2004-04-13 MX MXPA05010990A patent/MXPA05010990A/es active IP Right Grant
- 2004-04-13 NZ NZ543014A patent/NZ543014A/en not_active IP Right Cessation
- 2004-04-13 WO PCT/FR2004/000901 patent/WO2004092151A1/fr active IP Right Grant
- 2004-04-13 DE DE602004011917T patent/DE602004011917T2/de not_active Expired - Lifetime
- 2004-04-13 BR BRPI0409332-1A patent/BRPI0409332A/pt not_active IP Right Cessation
- 2004-04-13 KR KR1020057019582A patent/KR101117512B1/ko not_active IP Right Cessation
- 2004-04-13 PT PT04742484T patent/PT1615902E/pt unknown
- 2004-04-13 AU AU2004230302A patent/AU2004230302B8/en not_active Ceased
- 2004-04-13 CN CNB2004800097622A patent/CN1317271C/zh not_active Expired - Fee Related
- 2004-04-13 JP JP2006505793A patent/JP4664903B2/ja not_active Expired - Fee Related
-
2005
- 2005-10-09 IL IL171318A patent/IL171318A/en not_active IP Right Cessation
- 2005-10-11 ZA ZA200508209A patent/ZA200508209B/en unknown
- 2005-10-12 CO CO05104379A patent/CO5700730A2/es not_active Application Discontinuation
- 2005-11-11 NO NO20055332A patent/NO331813B1/no not_active IP Right Cessation
-
2006
- 2006-08-01 HK HK06108520A patent/HK1088306A1/xx not_active IP Right Cessation
-
2008
- 2008-05-12 CY CY20081100493T patent/CY1110375T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PE43697A1 (es) | Nueva clase de sulfonamidas, inhibidoras de la proteasa aspartilo | |
| GT200200121A (es) | Derivados aromaticos de acidos dicarboxilicos | |
| GT200300038A (es) | Nuevos derivados de piridina y quinolina | |
| BR0317696A (pt) | Composição para branqueamento | |
| ATE360045T1 (de) | Polycarbonatzusammensetzungen | |
| BRPI0608702A2 (pt) | Polímero, composição que absorve oxigênio, solução, artigo, e, processos para produzir um polímetro seqüestrante de oxigênio, e resina seqüestrante de oxigênio | |
| CO4950539A1 (es) | Derivados de aminoacidos inhibidores de las metaloproteasas de la matriz extracelular y de la liberacion del tnf . | |
| AR048876A1 (es) | Un proceso para preparar montelukast y compuestos intermedios para el mismo | |
| EA200600571A1 (ru) | Полипропиленовая пленка, полученная раздувом | |
| CO5580762A2 (es) | Analogos de lipoxina a4 | |
| AR051667A1 (es) | Uso de polisilazanos para recubrir tiras metalicas | |
| ES2535033T3 (es) | Derivados de 5,6 dihidroxi isoindol como conectores para la síntesis de oligómeros en fase sólida | |
| ATE443046T1 (de) | Organische verbindungen | |
| ATE431366T1 (de) | Verfahren zur herstellung von polymerverbindungen durch eliminierungsreaktion | |
| DK1706414T3 (da) | Fremgangsmåde til fluorcytidinderivater | |
| DK1644389T3 (da) | Pyrinidinforbindelser med phosphonatgrupper som antivirale nukleotidanaloger | |
| ES2189747T3 (es) | Procedimiento para la preparacion de taxanos a partir de 10-desacetilbacatina iii. | |
| CO4700291A1 (es) | Compuestos quimicos | |
| AR043986A1 (es) | Procedimiento de preparacion de 4, 10 beta-diacetoxi-2alfa-benzoiloxi-5beta, 20-epoxi-1, 13alfa-dihidroxi-9-oxo-19-norciclopropa (g) tax-11-eno | |
| AR025296A1 (es) | MÉTODO PARA INHIBIR LA POLIMERIZACIoN PREMATURA DE MONoMEROS VINIL AROMÁTICOS Y COMPOSICIoN DE MONoMEROS VINIL AROMÁTICOS Y DEL INHIBIDOR. | |
| ES2180524T3 (es) | Nuevos derivados de benceno-sulfon-amidas, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. | |
| AR000145A1 (es) | Composición polímerica de ácido naftalendicarboxilico que tiene fluorescencia reducida | |
| DK1730226T3 (da) | Alifatiske esterforbindelser som slipmidler i polyesterpolymerer | |
| NO20020425D0 (no) | Nye naftylsulfonsyrer og beslektede forbindelser som glukoseopptaksagonister | |
| CO4810290A1 (es) | Composiciones pesticidas |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |