AR041197A1 - Derivados triciclicos insecticidas - Google Patents

Derivados triciclicos insecticidas

Info

Publication number
AR041197A1
AR041197A1 ARP030103353A ARP030103353A AR041197A1 AR 041197 A1 AR041197 A1 AR 041197A1 AR P030103353 A ARP030103353 A AR P030103353A AR P030103353 A ARP030103353 A AR P030103353A AR 041197 A1 AR041197 A1 AR 041197A1
Authority
AR
Argentina
Prior art keywords
aryl
hydrogen
alkyl
alkoxy
halogen
Prior art date
Application number
ARP030103353A
Other languages
English (en)
Original Assignee
Fmc Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fmc Corp filed Critical Fmc Corp
Publication of AR041197A1 publication Critical patent/AR041197A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • A01N43/42—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/06—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings
    • A01N43/08—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings with oxygen as the ring hetero atom
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/06—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings
    • A01N43/10—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings with sulfur as the ring hetero atom
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/14—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings
    • A01N43/18—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings with sulfur as the ring hetero atom
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/22—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom rings with more than six members
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/62—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms three- or four-membered rings or rings with more than six members

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se ha encontrado que ciertos derivados tricíclicos han proporcionado una actividad insecticida inesperada. Estos compuestos son representados por la fórmula (1), donde R1 a R8, inclusive, y X e Y se describen en forma completa. También se revelan las composiciones que comprenden una cantidad efectiva como insecticida de por lo menos un compuesto de fórmula (1), y opcionalmente una cantidad efectiva de por lo menos un segundo compuesto, con por lo menos un portador insecticidamente compatible, juntamente con los métodos para controlar insectos que comprenden aplicar dichas composiciones al lugar donde los insectos se encuentran presentes o se espera que se encuentren presentes. Reivindicación 1: Una composición insecticida que comprende por lo menos una cantidad efectiva como insecticida de un compuesto de la fórmula (1) y por lo menos un portador insecticidamente compatible para la misma, en donde de R1 a R8, inclusive, son independientemente seleccionados entre hidrógeno, halógeno, alquilo, cicloalquilo, alquenilo, alquinilo, trialquilsililalquinilo, alcoxi, haloalquilo, haloalcoxi, alquiltio, alquilsulfinilo, alquilsulfonilo, haloalquiltio, haloalquilsulfinilo, haloalquilsulfonilo, dialquilaminosulfonilo, nitro, ciano, amino, formilo, o alquilcarbonilo; X es seleccionado entre -CR9R10-, -CR11R12CR13R14-, -CR15=CR16-, -NR17-, -CR18R19NR20-, o -CR21=N-; e Y es seleccionado entre -CR22R23-, -CR24R25CR26R27-, -CR28=CR29-, -NR30-, -CR31R32NR33-, -O-, -S-, -S(O)-, -S(O)2-, -CR34R35O-, -CR36R37S-, o -CR38=N-; where R9 y R10 son independientemente seleccionados entre hidrógeno, alquilo, o (piperidin-4-il)alquilo; o R9 y R10 pueden ser tomados conjuntamente con un resto de fórmula (2), o con =CHC2H4NR40R41, donde R39, R40 y R41 son independientemente seleccionados entre hidrógeno; alquilo; hidroxilalquilo; alcoxialquilo; alquiltioalquilo; alcoxicarbonilalquilo; haloalcoxicarbonilo; arilalquilo; ariloxialquilo; arilcarbonilalquilo; arilcarboniloxialquilo, en donde arilo es opcionalmente substituido con uno o más halógeno, alcoxi, haloalquilo, o arilo; o R40 y R41 pueden ser tomados conjuntamente con -C2H4N(CH3)C2H4- para formar un anillo piperazina; u es 0 o 1, y cuando u es 1, se forma un N-óxido; n es 0, y Ra es hidrógeno; o n es 1 a 8, y Ra es seleccionado entre opcionalmente substituido uno o más alquilo, alcoxialquilo, alcoxicarbonilo, y arilo, en donde arilo es opcionalmente substituido con uno o más halógeno, alcoxi, haloalquilo, o arilo; R11 es seleccionado entre hidrógeno, alquilo, alquilaminoalcoxi, dialquilaminoalcoxi, N(alquil)(alquilaminoalquilo), N(alquil)(dialquilaminoalquilo), alquilaminoalquilalquinilo, dialquilaminoalquilalquinilo, morfolinilo, imidazolinilo, alquilpirrolidiniloxi o el grupo de fórmulas (3) a (8), donde v es 0 o 1, y cuando v es 1, A es un grupo puente seleccionado entre -O-, -S-, -NH-, y -CH2-; u es tal como se define anteriormente; R42 a R45, inclusive, son independientemente seleccionados entre hidrógeno; alquilo; alquenilo; alquinilo; hidroxilalquilo; alcoxialquilo; alquiltioalquilo; alquilcarbonilo; alcoxicarbonilalquilo; haloalcoxicarbonilo; arilalquilo; ariloxialquilo; arilcarbonilalquilo; arilcarboniloxialquilo; heteroarilo; heteroarilalquilo; heteroarilalquilamino; en donde arilo y heteroarilo son opcionalmente substituidos con uno o más halógeno, alcoxi, haloalquilo, o arilo; o R43 y R44 pueden ser tomados conjuntamente con -C5H10- para formar un anillo de piperidina; m, p, y q son 0, y Rb, Rc y Rd son hidrógeno; o m es 1 a 8, p es 1 a 7, y q es 1 a 10, y Rb, Rc y Rd, respectivamente, son independientemente seleccionados entre uno o más alquilo, alcoxialquilo, alquilamino, dialquilamino, alcoxicarbonilo, o arilo, en donde arilo es opcionalmente substituido con uno o más halógeno, alcoxi, haloalquilo, o arilo; o R11 y R12 pueden ser tomados conjuntamente con la fórmula (2) donde Ra, n, u, y R39 son tal como se describe anteriormente; R12, cuando no se toma conjuntamente con R11 y R13, R14 y R16, son independientemente seleccionados entre hidrógeno, hidroxi, halógeno, alquilo, alcoxi, alquilcarbonilo, alquilcarboniloxi, alcoxicarbonilo, alcoxicarboniloxi, alquilaminocarbonilo, dialquilaminocarbonilo, alquilaminocarboniloxi, dialquilaminocarboniloxi, alquilaminosulfonilo, o dialquilaminosulfonilo; R15 es seleccionado entre las fórmulas (5) y (6) donde m, u, v, A, Rb y R42 tal como se definen anteriormente; R17 es hidrógeno; alquilo; alcoxialquilo; alcoxicarbonilo; dialquilaminoalquilo; alquilaminocarbonilo; dialquilaminocarbonilo; alquilsulfonilo; arilo, y arilalquilo en donde arilo es opcionalmente substituido con uno o más halógeno, alcoxi, haloalquilo, arilo; la fórmula (9); o -C3H6NR47R48 donde A, v, y u son tal como se definen anteriormente; R46 es seleccionado entre hidrógeno; alquilo; alquenilo; alquinilo; hidroxilalquilo; alcoxialquilo; alquiltioalquilo; alquilcarbonilo; alcoxicarbonilalquilo; haloalcoxicarbonilo; arilalquilo; ariloxialquilo; arilcarbonilalquilo; arilcarboniloxialquilo; heteroarilo; heteroarilalquilo; heteroarilalquilamino; en donde arilo y heteroarilo son opcionalmente substituidos con uno o más halógeno, alcoxi, haloalquilo, o arilo; R47 y R48 son independientemente seleccionados entre hidrógeno y alquilo; o R47 y R48 pueden ser tomados conjuntamente con -C5H10- para formar un anillo de piperidina, o con -C2H4N(CH3)C2H4-, o -C2H4N(C2H4OH)C2H4- para formar un anillo de piperazina; R18 y R19 son independientemente seleccionados entre hidrógeno, alquilo, amino, alquilaminoalquilo, y dialquilaminoalquilo; R20 es seleccionado entre hidrógeno; alquilo; alcoxialquilo; alcoxicarbonilo; dialquilaminoalquilo; alquilaminocarbonilo; dialquilaminocarbonilo; alquilsulfonilo; arilo, y arilalquilo en donde arilo es opcionalmente substituido con uno o más halógeno, alcoxi, haloalquilo, o arilo; R21 es seleccionado entre hidrógeno, alquilo o las fórmulas (10), (11) y (12) donde A, v, y u son tal como se define anteriormente; R49 a R52, inclusive, son independientemente seleccionados entre hidrógeno; alquilo; alquenilo, alquinilo, hidroxilalquilo; alcoxialquilo; alquiltioalquilo; alquilcarbonilo, alcoxicarbonilalquilo; haloalcoxicarbonilo; arilalquilo; ariloxialquilo; arilcarbonilalquilo; arilcarboniloxialquilo, heteroarilo, heteroarilalquilo, heteroarilalquilamino, en donde arilo y heteroarilo son opcionalmente substituidos con uno o más halógeno, alcoxi, haloalquilo, o arilo; o R50 y R51 pueden ser tomados conjuntamente con -C5H10- para formar un anillo de piperidina; r, s y t son 0, y Re, Rf, y Rg son hidrógeno, o r es 1 a 8, s es 1 a 7, t es 1 a 10, y Re, Rf, y Rg, respectivamente, son independientemente seleccionados entre uno o más alquilo, alcoxialquilo, alquilamino, dialquilamino, alcoxicarbonilo, o arilo, en donde arilo es opcionalmente substituido con uno o más halógeno, alcoxi, haloalquilo, o arilo; R22 a R29, inclusive, son independientemente seleccionados entre hidrógeno y alquilo; R30 es seleccionado entre hidrógeno; alquilo; alcoxialquilo; alcoxicarbonilo; dialquilaminoalquilo; alquilaminocarbonilo; dialquilaminocarbonilo; alquilsulfonilo; arilo, y arilalquilo en donde arilo es opcionalmente substituido con uno o más halógeno, alcoxi, haloalquilo, o arilo; R31 y R32 son independientemente seleccionados entre hidrógeno y alquilo, R33 es seleccionado entre hidrógeno; alquilo; alcoxialquilo; alcoxicarbonilo; dialquilaminoalquilo; alquilaminocarbonilo; dialquilaminocarbonilo; alquilsulfonilo; arilo, y arilalquilo en donde arilo es opcionalmente substituido con uno o más halógeno, alcoxi, haloalquilo, o arilo; R34 a R38, inclusive, son independientemente seleccionados entre hidrógeno, y alquilo; y, sales agrícolamente aceptables del mismo.
ARP030103353A 2002-09-18 2003-09-16 Derivados triciclicos insecticidas AR041197A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41192602P 2002-09-18 2002-09-18

Publications (1)

Publication Number Publication Date
AR041197A1 true AR041197A1 (es) 2005-05-04

Family

ID=32030765

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP030103353A AR041197A1 (es) 2002-09-18 2003-09-16 Derivados triciclicos insecticidas

Country Status (12)

Country Link
US (1) US20060111342A1 (es)
EP (1) EP1538906A2 (es)
JP (1) JP2005539076A (es)
KR (1) KR20050048633A (es)
CN (1) CN1681388A (es)
AR (1) AR041197A1 (es)
AU (1) AU2003272362A1 (es)
BR (1) BR0314108A (es)
MX (1) MXPA05002884A (es)
TW (1) TW200418383A (es)
WO (1) WO2004026030A2 (es)
ZA (1) ZA200501774B (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050049146A1 (en) * 2001-11-05 2005-03-03 Chiarello John F. Use of substituted dibenzothiepine derivatives as insecticidal, acaricidal and nematicidal agents
US20050085463A1 (en) * 2003-01-23 2005-04-21 Weiner David M. Use of N-desmethylclozapine to treat human neuropsychiatric disease
NZ541014A (en) * 2003-01-23 2008-05-30 Acadia Pharm Inc Use of N-desmethylclozapine to treat schizophrenia while increasing the level of activity of a muscarinic receptor
US20050250767A1 (en) * 2003-01-23 2005-11-10 Weiner David M Use of N-desmethylclozapine to treat human neuropsychiatric disease
EP1644373A1 (en) 2003-06-27 2006-04-12 Janssen Pharmaceutica N.V. Tricyclic delta opioid modulators
WO2005063254A2 (en) * 2003-12-22 2005-07-14 Acadia Pharmaceuticals Inc. Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders
AU2005257768A1 (en) * 2004-04-01 2006-01-05 Acadia Pharmaceuticals Inc. Method of synthesis and isolation of solid N-desmethylclozapine and crystalline forms thereof
EA200700403A1 (ru) 2004-08-05 2007-08-31 Янссен Фармацевтика Н.В. ТРИЦИКЛИЧЕСКИЕ δ-ОПИОИДНЫЕ МОДУЛЯТОРЫ
EA011674B1 (ru) 2004-12-22 2009-04-28 Янссен Фармацевтика Н.В. ТРИЦИКЛИЧЕСКИЕ δ-ОПИОИДНЫЕ МОДУЛЯТОРЫ
BRPI0519201A2 (pt) 2004-12-22 2008-12-30 Janssen Pharmaceutica Nv moduladores de delta-opiàide tricÍclico
WO2006074388A2 (en) 2005-01-06 2006-07-13 Janssen Pharmaceutica N.V. TRICYCLIC δ-OPIOID MODULATORS
DE602006018604D1 (de) 2005-06-16 2011-01-13 Janssen Pharmaceutica Nv Tricyclische opioidmodulatoren
WO2007053618A1 (en) * 2005-10-31 2007-05-10 Acadia Pharmaceuticals Inc. Prodrugs of muscarinic agonists and methods of treatment of neuropsychiatric disorders
WO2009071631A2 (en) * 2007-12-05 2009-06-11 Janssen Pharmaceutica Nv Dibenzoazepine and dibenzooxazepine trpa1 agonists
TWI488854B (zh) 2008-06-20 2015-06-21 Astrazeneca Ab 二苯并噻氮呯衍生物及其用途
HUE045805T2 (hu) * 2014-08-19 2020-01-28 Nihon Nohyaku Co Ltd Oxazepin vegyület, peszticid mezõgazdasági és kertészeti alkalmazásra, amely hatóanyagként tartalmazza az említett vegyületet, és eljárás az említett, mezõgazdasági és kertészeti alkalmazásra szolgáló peszticid alkalmazására
TWI698430B (zh) * 2015-02-13 2020-07-11 南北兄弟藥業投資有限公司 三環化合物及其在藥物中的應用
CN110128432B (zh) * 2018-02-02 2021-03-02 广东东阳光药业有限公司 含氮三环化合物及其在药物中的应用
CN109897027B (zh) * 2019-04-28 2021-11-02 梯尔希（南京）药物研发有限公司 一种3-羟基地氯雷他定代谢物的合成方法
CA3154630A1 (en) 2019-10-21 2021-04-29 Mark E. Duggan 3-(4-(11h-dibenzo[b,e][1,4]azepin-6-yl)piperazin-1-yl)- and 3-(4-(dibenzo[b,f][1,4]oxazepin/thiazepin/diazepin-11-yl)piperazin-1-yl)-propano ic acid derivatives as h1 and 5-ht2a-receptor modulators for the treatment of sleep disorders
IL298646A (en) * 2020-06-03 2023-01-01 Sound Agriculture Company Compounds and methods for stimulating plants

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE669599A (es) * 1964-09-17 1965-12-31
US3357998A (en) * 1964-11-06 1967-12-12 Searle & Co Complex amides of dihydrodibenzo [b, f] [1, 4] oxazepine-10-carboxylic acids
US3436397A (en) * 1966-05-23 1969-04-01 American Home Prod Dibenzocyclohepten-5-ylidene thiazolidinones
CH624682A5 (es) * 1976-11-10 1981-08-14 Sandoz Ag
US4777177A (en) * 1984-10-19 1988-10-11 Ciba-Geigy Corporation Pesticidal thioxanthen-9-ylidenepiperidines
JPS61106573A (ja) * 1984-10-19 1986-05-24 チバ‐ガイギー　アクチエンゲゼルシヤフト チオキサンテン‐９‐イリデン‐ピペリジン、その製法及び核化合物を含有する有害生物防除剤
WO1993000811A1 (en) * 1991-07-01 1993-01-21 The General Hospital Corporation Invertebrate phenylethanolamine transporter and the use thereof
US5538965A (en) * 1993-12-23 1996-07-23 Allelix Biopharmaceuticals Inc. Dopamine receptor ligands
US5436333A (en) * 1994-08-08 1995-07-25 American Cyanamid Company Process for the preparation of tricyclic-heterocycles
US5602124A (en) * 1994-12-12 1997-02-11 Allelix Biopharmaceuticals, Inc. 5-HT2 receptor ligands
US20050049146A1 (en) * 2001-11-05 2005-03-03 Chiarello John F. Use of substituted dibenzothiepine derivatives as insecticidal, acaricidal and nematicidal agents

Also Published As

Publication number Publication date
JP2005539076A (ja) 2005-12-22
BR0314108A (pt) 2006-04-25
KR20050048633A (ko) 2005-05-24
ZA200501774B (en) 2005-11-30
TW200418383A (en) 2004-10-01
WO2004026030A3 (en) 2004-06-03
AU2003272362A1 (en) 2004-04-08
EP1538906A2 (en) 2005-06-15
CN1681388A (zh) 2005-10-12
US20060111342A1 (en) 2006-05-25
MXPA05002884A (es) 2005-06-22
WO2004026030A2 (en) 2004-04-01

Similar Documents

Publication Publication Date Title
AR041197A1 (es) Derivados triciclicos insecticidas
AR066144A1 (es) Derivados de aril pirrolidinas utiles como insecticidas y/o acaricidas y composiciones insecticidas que los contienen.
AR122776A2 (es) Composiciones parasiticidas que comprenden un agente activo de isoxazolina, sus métodos y usos
ES2395704T3 (es) Derivados de isoxazolina y su uso como pesticida
AR095079A1 (es) Derivados de octahidro-pirrolo[3,4-c]-pirrol y piridina-fenilo
AR030762A1 (es) Piridinilamidas e imidas para usar como fungicidas
AR061831A2 (es) Composicion herbicida selectiva y metodo para combatir el crecimiento de plantas perjudiciales en cultivos de plantas utiles
AR056031A1 (es) Insecticidas benzheterociclicos
AR037754A1 (es) Herbicidas
AR057974A1 (es) Derivados de pirazolcarboxanilida o sales de los mismos, compuestos intermedios de los mismos, agentes agrohorticolas, y metodos para utilizacion de los mismos
RU2009141185A (ru) Инсектицидные производные арилизоксазолина
AR054024A1 (es) Derivados de piridina -3- carboxamida como agonistas inversos de cb1
AR046790A1 (es) Pirimidinas herbicidas. mezclas que las contienen.
PE20060691A1 (es) Serinamidas sustituidas por benzoilo
AR049433A1 (es) Derivados de naftalina
MY133385A (en) Benzazoles: benzoxazoles, benzthiazole and benzimidazole derivatives
PE20001464A1 (es) Derivados quinolin-2-ona sustituidos con heteroarilo utiles como agentes anticancerigenos
AR057954A1 (es) Compuestos derivados de acido tartarico, composiciones farmaceuticas que los contienen y usos como agentes antimicrobianos.
AR037901A1 (es) Beta-amino-alfa-cianoacrilatos
AR056883A1 (es) Derivados de 7-azaindol-2 carboxamida, un proceso para la preparacion de los mismos, composiciones farmaceuticas que los contienen y su uso en la fabricacion de un medicamento para el tratamiento de enfermedades asociadas con la modulacion de receptores de h3
NO20081551L (no) Heterocyklisk substituerte pyridinderivater og antisoppmidler inneholdende samme
AR084317A1 (es) 6-(2-aminofenil)-picolinatos y su uso como herbicidas
AR113990A1 (es) Pirazolopiridina-diamidas, su uso como insecticida y procesos para prepararlas
AR041668A1 (es) Uso de antagonistas del canal sodico neuronal para el control de ectoparasitos en animales homeotermicos
AR057197A1 (es) Derivados de 1, 1-dioxo-tiomorfolinil-indolil-metanona

Legal Events

Date Code Title Description
FA Abandonment or withdrawal