AR041037A1 - Uso terapeutico n-(3-metoxi-5-metilpirazin-2-il)-2-(4-[1,3,4-oxadiazol-2-il]fenil)piridin-3-sulfonamida - Google Patents

Uso terapeutico n-(3-metoxi-5-metilpirazin-2-il)-2-(4-[1,3,4-oxadiazol-2-il]fenil)piridin-3-sulfonamida

Info

Publication number
AR041037A1
AR041037A1 ARP030103041A ARP030103041A AR041037A1 AR 041037 A1 AR041037 A1 AR 041037A1 AR P030103041 A ARP030103041 A AR P030103041A AR P030103041 A ARP030103041 A AR P030103041A AR 041037 A1 AR041037 A1 AR 041037A1
Authority
AR
Argentina
Prior art keywords
cancer
oxadiazol
sulfonamide
phenyl
methylpirazin
Prior art date
Application number
ARP030103041A
Other languages
English (en)
Inventor
Marianne Ashford
Nigel Barras
Francis Boyle
Andrew Hughes
Donna Johnstone
Sina Taylor
David Tonge
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9942847&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR041037(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of AR041037A1 publication Critical patent/AR041037A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Se describe el uso de N-(3-metoxi-5-metilpirazin-2-il)-2-(4-[1,3,4-oxadiazol-2-il]fenil)piridin-3-sulfonamida, o una sal de la misma aceptable para uso farmacéutico, en el tratamiento del cáncer y/o el dolor de un animal de sangre caliente, tal como el hombre. Reivindicación 6: El uso de acuerdo con cualquiera de las reivindicaciones 1,caracterizado porque el cáncer es cáncer de esófago, mieloma, hepatocelular, pancreático, cáncer cervical, tumor de Ewings, neuroblastoma, sarcoma de Kaposi, cáncer de ovario, cáncer de mama, cáncer colorrectal, cáncer de próstata, cáncer de vejiga, melanoma, cáncer de pulmón - cáncer de células no pequenas de pulmón (NSCLC) y cáncer de células pequenas de pulmón (SCLC), cáncer gástrico, cáncer de cabeza y cuello, cáncer renal, linfoma y leucemia.
ARP030103041A 2002-08-23 2003-08-22 Uso terapeutico n-(3-metoxi-5-metilpirazin-2-il)-2-(4-[1,3,4-oxadiazol-2-il]fenil)piridin-3-sulfonamida AR041037A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0219660.8A GB0219660D0 (en) 2002-08-23 2002-08-23 Therapeutic use

Publications (1)

Publication Number Publication Date
AR041037A1 true AR041037A1 (es) 2005-04-27

Family

ID=9942847

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP030103041A AR041037A1 (es) 2002-08-23 2003-08-22 Uso terapeutico n-(3-metoxi-5-metilpirazin-2-il)-2-(4-[1,3,4-oxadiazol-2-il]fenil)piridin-3-sulfonamida

Country Status (32)

Country Link
US (2) US7820679B2 (es)
EP (2) EP2072082A3 (es)
JP (2) JP3663202B2 (es)
KR (1) KR20050035280A (es)
CN (1) CN100467023C (es)
AR (1) AR041037A1 (es)
AT (1) ATE427773T1 (es)
AU (1) AU2003255835B8 (es)
BR (1) BR0313655A (es)
CA (1) CA2496476C (es)
CL (1) CL2003001692A1 (es)
CY (1) CY1110712T1 (es)
DE (1) DE60327084D1 (es)
DK (1) DK1545710T3 (es)
ES (1) ES2323309T3 (es)
GB (1) GB0219660D0 (es)
HK (1) HK1077534A1 (es)
IL (1) IL166730A0 (es)
IS (1) IS2704B (es)
MX (1) MXPA05001862A (es)
MY (2) MY136449A (es)
NO (1) NO330756B1 (es)
NZ (1) NZ538114A (es)
PL (1) PL375561A1 (es)
PT (1) PT1545710E (es)
RU (1) RU2340343C2 (es)
SA (1) SA03240363B1 (es)
SI (1) SI1545710T1 (es)
TW (1) TWI302912B (es)
UA (1) UA82071C2 (es)
WO (1) WO2004018044A2 (es)
ZA (1) ZA200501267B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0403744D0 (en) 2004-02-20 2004-03-24 Astrazeneca Ab Chemical process
GB0425854D0 (en) * 2004-11-25 2004-12-29 Astrazeneca Ab Therapeutic treatment
GB0514743D0 (en) * 2005-07-19 2005-08-24 Astrazeneca Ab Salt
WO2007111350A1 (ja) * 2006-03-28 2007-10-04 Osaka Bioscience Institute 血管新生ならびに癌細胞のmesenchymal型およびamoeboid型浸潤を阻害するための薬剤
US20090062246A1 (en) * 2007-08-17 2009-03-05 Astrazeneca Ab Therapeutic treatment-014
TW200924768A (en) 2007-10-12 2009-06-16 Astrazeneca Ab Composition
WO2009068906A2 (en) * 2007-11-26 2009-06-04 Astrazeneca Ab Combinations comprising zd4054 and a src family kinase inhibitor 172
WO2010004337A1 (en) * 2008-07-10 2010-01-14 Astrazeneca Ab Combinations comprising n-(3-methoxy-5-methylpyrazin-2-yl)-2- (4-[1,3,4-oxadiazol-2-yl]phenyl)pyridine-3-sulphonamide and pemetrexed
RU2631487C2 (ru) * 2011-05-17 2017-09-22 Плексксикон Инк. Модуляция киназ и показания к её применению
CN102491973A (zh) * 2011-12-15 2012-06-13 南京友杰医药科技有限公司 Zd-4054的合成方法
KR101855382B1 (ko) * 2015-12-31 2018-05-04 경북대학교 산학협력단 설폰아마이드계 화합물을 유효성분으로 포함하는 암의 예방, 치료 및 전이 억제용 약학적 조성물

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Also Published As

Publication number Publication date
CA2496476A1 (en) 2004-03-04
AU2003255835B2 (en) 2007-04-05
EP2072082A3 (en) 2009-12-23
US20060094729A1 (en) 2006-05-04
TWI302912B (en) 2008-11-11
DK1545710T3 (da) 2009-06-29
ATE427773T1 (de) 2009-04-15
UA82071C2 (en) 2008-03-11
CN1688365A (zh) 2005-10-26
MY137595A (en) 2009-02-27
WO2004018044A8 (en) 2004-06-24
EP2072082A2 (en) 2009-06-24
HK1077534A1 (en) 2006-02-17
DE60327084D1 (de) 2009-05-20
BR0313655A (pt) 2005-06-21
RU2005108349A (ru) 2005-08-27
US20110003831A1 (en) 2011-01-06
SA03240363B1 (ar) 2009-04-11
ES2323309T3 (es) 2009-07-13
AU2003255835B8 (en) 2007-05-17
CY1110712T1 (el) 2015-06-10
US7820679B2 (en) 2010-10-26
NO20050689L (no) 2005-03-21
WO2004018044A3 (en) 2004-05-06
JP2004083590A (ja) 2004-03-18
NO330756B1 (no) 2011-07-04
PL375561A1 (en) 2005-11-28
CN100467023C (zh) 2009-03-11
IS2704B (is) 2010-12-15
EP1545710B1 (en) 2009-04-08
PT1545710E (pt) 2009-05-26
CL2003001692A1 (es) 2005-01-21
JP3663202B2 (ja) 2005-06-22
EP1545710A2 (en) 2005-06-29
NZ538114A (en) 2008-02-29
AU2003255835A1 (en) 2004-03-11
WO2004018044A2 (en) 2004-03-04
ZA200501267B (en) 2006-10-25
IL166730A0 (en) 2006-01-15
MXPA05001862A (es) 2005-06-03
MY136449A (en) 2008-10-31
SI1545710T1 (sl) 2009-08-31
KR20050035280A (ko) 2005-04-15
CA2496476C (en) 2009-08-04
GB0219660D0 (en) 2002-10-02
TW200409768A (en) 2004-06-16
RU2340343C2 (ru) 2008-12-10
JP2005097312A (ja) 2005-04-14
IS7766A (is) 2005-03-22

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