AR039727A1 - Difluorotioacetamidas de oxazolidinonas como agentes antibacterianos y composicion farmaceutica en base a ellas - Google Patents

Difluorotioacetamidas de oxazolidinonas como agentes antibacterianos y composicion farmaceutica en base a ellas

Info

Publication number
AR039727A1
AR039727A1 ARP030102259A ARP030102259A AR039727A1 AR 039727 A1 AR039727 A1 AR 039727A1 AR P030102259 A ARP030102259 A AR P030102259A AR P030102259 A ARP030102259 A AR P030102259A AR 039727 A1 AR039727 A1 AR 039727A1
Authority
AR
Argentina
Prior art keywords
antibacterial agents
difluorotioacetamids
oxazolidinone
pharmaceutical composition
composition based
Prior art date
Application number
ARP030102259A
Other languages
English (en)
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of AR039727A1 publication Critical patent/AR039727A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Difluorotioacetamida-oxazolidinonas como agentes antibacterianos y terapias antimicrobianas combinadas para combatir enfermedades infecciosas causadas por bacterias gram positivas y gram negativas. Reivindicación 1: Un compuesto de fórmula (1) o una sal farmacéuticamente aceptable del compuesto en donde R es -CH2- o CH2CH2-; R2 y R3 son independientemente -H o -F; X es -N- o -CH; Y es -SO-, -SO2-, o -SONR4-; y R4 es -H o -C1-4alquilo.
ARP030102259A 2002-06-28 2003-06-24 Difluorotioacetamidas de oxazolidinonas como agentes antibacterianos y composicion farmaceutica en base a ellas AR039727A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US39221302P 2002-06-28 2002-06-28

Publications (1)

Publication Number Publication Date
AR039727A1 true AR039727A1 (es) 2005-03-09

Family

ID=30000829

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP030102259A AR039727A1 (es) 2002-06-28 2003-06-24 Difluorotioacetamidas de oxazolidinonas como agentes antibacterianos y composicion farmaceutica en base a ellas

Country Status (10)

Country Link
US (1) US6927229B2 (es)
EP (1) EP1519924A1 (es)
JP (1) JP2005533818A (es)
AR (1) AR039727A1 (es)
AU (1) AU2003239581A1 (es)
BR (1) BR0312211A (es)
CA (1) CA2489411A1 (es)
MX (1) MXPA05000027A (es)
TW (1) TW200403240A (es)
WO (1) WO2004002967A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2175324C2 (ru) * 1995-09-01 2001-10-27 Фармация Энд Апджон Компани Фенилоксазолидиноны, имеющие с-с-связь с 4-8-членными гетероциклическими кольцами
ITMI20021725A1 (it) * 2002-08-01 2002-10-31 Zambon Spa Composizioni farmaceutiche ad attivita' antibiotica.
US7265140B2 (en) * 2003-09-23 2007-09-04 Pfizer Inc Acyloxymethylcarbamate prodrugs of oxazolidinones
CA2589171A1 (en) * 2004-11-29 2006-06-01 Pharmacia & Upjohn Company Llc Thiazepine oxazolidinones as antibacterial agents
DE602006010702D1 (de) 2005-06-29 2010-01-07 Pharmacia & Upjohn Co Llc Homomorpholinoxazolidinone als antibakterielle mittel
CN101460495B (zh) 2006-03-31 2013-08-14 财团法人乙卯研究所 具有杂环的化合物
WO2008069619A1 (en) * 2006-12-08 2008-06-12 Legochem Bioscience Ltd. Novel oxazolidinone derivatives, process for preparing thereof and pharmaceutical composition containing the same
EP2018864A1 (en) 2007-07-23 2009-01-28 Biomet Deutschland GmbH Pharmaceutical composition, substrate comprising a pharmaceutical composition, and use of a pharmaceutical composition
EP2233484A3 (en) 2007-10-02 2012-04-04 Research Foundation Itsuu Laboratory Oxazolidinone derivatives having a 7-membered heterocyclic ring
EA037643B1 (ru) * 2015-07-17 2021-04-26 Зе Глобал Эллайенс Фо Тб Драг Девелопмент, Инк. Замещенные фенилоксазолидиноны для антимикробной терапии
WO2018071314A1 (en) 2016-10-10 2018-04-19 Bristol-Myers Squibb Company Tricyclic sulfones as ror gamma modulators
CN110721153A (zh) * 2019-10-08 2020-01-24 四川太平洋药业有限责任公司 一种盐酸莫西沙星氯化钠注射液及制备工艺

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2175324C2 (ru) * 1995-09-01 2001-10-27 Фармация Энд Апджон Компани Фенилоксазолидиноны, имеющие с-с-связь с 4-8-членными гетероциклическими кольцами
US6255304B1 (en) * 1997-05-30 2001-07-03 Pharmacia & Upjohn Company Oxazolidinone antibacterial agents having a thiocarbonyl functionality
UA66401C2 (en) * 1998-12-02 2004-05-17 Sentor Pharmaceuticals Inc 3,4,5-trisubstituted aryl nitrone compounds and pharmaceutical composition containing the same
PE20010851A1 (es) * 1999-12-14 2001-08-17 Upjohn Co Esteres del acido benzoico de oxazolidinonas que tienen un substituyente hidroxiacetilpiperazina
PL356478A1 (en) 1999-12-21 2004-06-28 Pharmacia & Upjohn Company Oxazolidinones having a sulfoximine functionality and their use as antimicrobial agents
KR20020072311A (ko) 2000-02-10 2002-09-14 파마시아 앤드 업존 캄파니 피페라진 아미드 치환기를 갖는 옥사졸리디논 티오아미드
PE20020044A1 (es) * 2000-06-16 2002-01-30 Upjohn Co Tiazina oxazolidinona

Also Published As

Publication number Publication date
BR0312211A (pt) 2007-05-29
US20040077626A1 (en) 2004-04-22
AU2003239581A1 (en) 2004-01-19
MXPA05000027A (es) 2005-08-26
EP1519924A1 (en) 2005-04-06
US6927229B2 (en) 2005-08-09
CA2489411A1 (en) 2004-01-08
WO2004002967A1 (en) 2004-01-08
TW200403240A (en) 2004-03-01
JP2005533818A (ja) 2005-11-10

Similar Documents

Publication Publication Date Title
AR038576A1 (es) Formulaciones de drogas antibioticas oftalmicas que contienen un compuesto de ciclodextrina y cloruro de cetil piridinio
EA200501098A1 (ru) Антибактериальные агенты
AR039727A1 (es) Difluorotioacetamidas de oxazolidinonas como agentes antibacterianos y composicion farmaceutica en base a ellas
ATE502633T1 (de) Cyclosporins zur behandlung und vorbeugung von augenerkrankungen
DE60331056D1 (de) 6-11 bicyclische ketolidderivate
MX2007010072A (es) Derivados de piperidina antibacterianos.
UA92746C2 (en) Thiazole compounds and methods of use
WO2005014585A8 (en) Halogenated quinazolinyl nitrofurans as antibacterial agents
DE69529670D1 (de) Oxazolidinon derivate und diese enthaltende pharmazeutische zusammensetzungen
TW200600492A (en) Substituted aryl acylthioureas and related compounds; inhibitors of viral replication
NI201200089A (es) INHIBIDORES DE N1 - PIRAZOLOESPIROCETONA ACETIL - CoA CARBOXILASA.
MY145647A (en) (4-hydroxy-2-oxo-3h-benzothiazol-7-yl)ethylamine derivatives, processes for their preparation, pharmaceutical compositions containing them and their use in therapy (for example in the treatment of respiratory disease states)
DE602008004540D1 (de) 2-oxo-2-(2-phenyl-5,6,7,8-tetrahydroindolizin-3-yl)acetamidderivate und verwandte verbindungen als antipilzmittel
MX359435B (es) Derivados novedosos de cefalosporinas y composiciones farmaceuticas de estos.
AR042706A1 (es) Compuestos (2-carboxamido)(3-amino) tiofenos y su uso para el tratamiento del cancer
NO331012B1 (no) N-sulfonyl-4-metylenamino-3-hydroksy-2-pyridoner som antimikrobielle midler
ES2186550A1 (es) Nuevos derivados de oxazolidinonas como antibacterianos.
UY28924A1 (es) Compuestos antibioticos particularmente conteniendo anillos de oxazolidinona y isoxazolina sustituidos, composiciones farmaceuticas, preparación, intermedios para ello y su uso terapeutico.
BR9910443A (pt) Aperfeiçoamento da atividade de agentes antibacterianos de oxazolidinona usando-se derivados de arginina
CO5560555A2 (es) Cristales de derivado de hidroxinorefedrina
AR023264A1 (es) Derivados de eritromicina
BRPI0413413A (pt) feniloxazolidinonas de piperidino substituìdo tendo atividade antimicrobiana com eficácia in vivo melhorada
GEP20084306B (en) Antibacterial indolone oxazolidinones, intermediates for their preparation and pharmaceutical compositions containing them
ECSP045397A (es) 6-ALQUILIDEN-PENEMS BICÍCLICOS COMO INHIBIDORES DE LAS b-LACTAMASAS
EA200800151A1 (ru) Производные хинолина в качестве антибактериальных агентов

Legal Events

Date Code Title Description
FB Suspension of granting procedure