AR038371A1 - Formulaciones de azitromicina granuladas por via seca - Google Patents
Formulaciones de azitromicina granuladas por via secaInfo
- Publication number
- AR038371A1 AR038371A1 ARP030100270A ARP030100270A AR038371A1 AR 038371 A1 AR038371 A1 AR 038371A1 AR P030100270 A ARP030100270 A AR P030100270A AR P030100270 A ARP030100270 A AR P030100270A AR 038371 A1 AR038371 A1 AR 038371A1
- Authority
- AR
- Argentina
- Prior art keywords
- azithromycin
- dihydrate
- pharmaceutical formulation
- mga
- forms
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Formulación farmacéutica, en forma de comprimido, sobrecillo o polvo para formar una forma de dosificación en suspensión, que comprende partículas granuladas por vía seca de una forma no dihidrato de la azitromicina y, opcionalmente, uno o más excipientes farmacéuticamente aceptables. La formulación farmacéutica es un comprimido que contiene entre aproximadamente 40% en peso y aproximadamente 85% en peso de azitromicina no dihidrato. Más preferiblemente, la formulación farmacéutica contiene azitromicina no dihidrato seleccionada de las formas B, D, E, F, G, H, J, M, N, O, P, Q, R, o de sus mezclas. Incluso más preferiblemente, la presente se refiere a una formulación farmacéutica en la que la dosificación de azitromicina es 250 mgA, 500 mgA, 600mgA ó 1000 mgA. La presente se refiere además a una partícula de azitromicina granulada por vía seca, que comprende una forma de azitromicina, seleccionada de las formas D, E, F, G, H, J, M, N, O, P, Q, R y mezclas de formas no dihidrato, y al menos un excipiente farmacéuticamente aceptable.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35404102P | 2002-02-01 | 2002-02-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR038371A1 true AR038371A1 (es) | 2005-01-12 |
Family
ID=27663280
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP030100270A AR038371A1 (es) | 2002-02-01 | 2003-01-30 | Formulaciones de azitromicina granuladas por via seca |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US7438924B2 (es) |
| EP (1) | EP1478347A1 (es) |
| JP (1) | JP2005526020A (es) |
| KR (1) | KR100676025B1 (es) |
| CN (1) | CN1646104A (es) |
| AR (1) | AR038371A1 (es) |
| AU (1) | AU2003201146B2 (es) |
| BR (1) | BR0307331A (es) |
| CA (1) | CA2474809A1 (es) |
| CO (1) | CO5611118A2 (es) |
| MX (1) | MXPA04007427A (es) |
| NO (1) | NO20043644L (es) |
| NZ (1) | NZ534234A (es) |
| PL (1) | PL372394A1 (es) |
| RU (1) | RU2283092C2 (es) |
| TW (1) | TW200306865A (es) |
| WO (1) | WO2003063838A1 (es) |
| ZA (1) | ZA200405805B (es) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20020231A2 (en) | 2002-03-18 | 2003-12-31 | Pliva D D | ISOSTRUCTURAL PSEUDOPOLYMORPHS OF 9-DEOXO-9a-AZA-9a-METHYL-9a-HOMOERYTHROMYCIN A |
| EP1455758A1 (en) * | 2001-12-21 | 2004-09-15 | Pfizer Products Inc. | Directly compressible formulations of azithromycin |
| HRP20020614A2 (en) | 2002-07-22 | 2004-06-30 | PLIVA-ISTRAŽIVAČKI INSTITUT d.o.o. | Rhombic pseudopolymorph of 9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin a |
| SI1551372T1 (en) * | 2002-09-20 | 2018-08-31 | Alpharma Pharmaceuticals Llc | SUBVENCATION DATA AND RELATED CONSTRUCTIONS AND PROCEDURES |
| JP3444874B1 (ja) * | 2002-12-02 | 2003-09-08 | 高砂香料工業株式会社 | 顆粒状香料およびその製造方法 |
| WO2005002592A2 (en) * | 2003-07-01 | 2005-01-13 | Ranbaxy Laboratories Limited | Stable oral compositions of azithromycin monohydrate |
| US6984403B2 (en) * | 2003-12-04 | 2006-01-10 | Pfizer Inc. | Azithromycin dosage forms with reduced side effects |
| BRPI0416534A (pt) * | 2003-12-04 | 2007-01-09 | Pfizer Prod Inc | composições multiparticuladas com estabilidade melhorada |
| AP2218A (en) * | 2003-12-04 | 2011-04-20 | Pfizer Prod Inc | Azithromycin dosage forms with reduced side effects |
| ATE399536T1 (de) | 2003-12-04 | 2008-07-15 | Pfizer Prod Inc | Verfahren zur herstellung von pharmazeutischen multiteilchenförmigen produkten |
| WO2005053652A1 (en) | 2003-12-04 | 2005-06-16 | Pfizer Products Inc. | Multiparticulate crystalline drug compositions containing a poloxamer and a glyceride |
| US7468428B2 (en) | 2004-03-17 | 2008-12-23 | App Pharmaceuticals, Llc | Lyophilized azithromycin formulation |
| JP2008524317A (ja) * | 2004-12-21 | 2008-07-10 | ファイザー・プロダクツ・インク | 腸溶コーティングされたアジスロマイシン多粒子 |
| EA013161B1 (ru) * | 2005-06-08 | 2010-02-26 | Орион Корпорейшн | Дозированная форма для перорального применения |
| NZ599069A (en) * | 2006-06-30 | 2013-10-25 | Iceutica Pty Ltd | Methods for the Preparation of Biologically Active Compounds in Nanoparticulate Form |
| IN2014MN00380A (es) | 2006-06-30 | 2015-06-19 | Iceutica Pty Ltd | |
| BRPI0718320A2 (pt) * | 2006-10-27 | 2013-11-26 | Janssen Pharmaceutica Nv | Composições farmacêuticas secas granuladas e métodos para produzir as mesmas. |
| FI20070521L (fi) * | 2006-11-10 | 2008-05-11 | Atacama Labs Oy | Rakeita, tabletteja ja rakeistusmenetelmä |
| US8951562B2 (en) | 2006-11-10 | 2015-02-10 | Atacama Labs Oy | Method and apparatus or dry granulation |
| WO2008084828A1 (ja) * | 2007-01-11 | 2008-07-17 | Kaneka Corporation | 補酵素ｑ10粒子の製造方法 |
| EP2291233B1 (en) * | 2008-05-09 | 2019-09-04 | Atacama Labs Oy | Method for dry granulation |
| US8106111B2 (en) | 2009-05-15 | 2012-01-31 | Eastman Chemical Company | Antimicrobial effect of cycloaliphatic diol antimicrobial agents in coating compositions |
| PL2651398T3 (pl) | 2010-12-16 | 2018-05-30 | Novo Nordisk A/S | Stałe kompozycje zawierające agonistę GLP-1 i sól kwasu N-(8-(2-hydroksybenzoilo)amino)kaprylowego |
| WO2012091039A1 (ja) * | 2010-12-27 | 2012-07-05 | 富田製薬株式会社 | 粒子状製剤 |
| CN103619175B (zh) | 2011-04-12 | 2016-08-17 | 诺沃—诺迪斯克有限公司 | 双酰化glp-1衍生物 |
| WO2013088274A1 (en) | 2011-12-14 | 2013-06-20 | Wockhardt Limited | Anhydrous amorphous azithromycin composition free of azithromycin dihydrate |
| JP6356660B2 (ja) | 2012-03-22 | 2018-07-11 | ノヴォ ノルディスク アー／エス | 送達剤を含む組成物およびその調製 |
| HRP20231060T1 (hr) | 2012-03-22 | 2023-12-22 | Novo Nordisk A/S | Pripravci peptida glp-1 i njihova priprava |
| TR201903918T4 (tr) | 2012-03-22 | 2019-04-22 | Novo Nordisk As | Bir dağıtım ajanı içeren bileşimler ve bunların hazırlanması. |
| CN104487056A (zh) | 2012-06-20 | 2015-04-01 | 诺和诺德A/S（股份有限公司） | 包含肽和递送剂的片剂制剂 |
| EP3746111B1 (en) | 2018-02-02 | 2023-07-19 | Novo Nordisk A/S | Solid compositions comprising a glp-1 agonist, a salt of n-(8-(2-hydroxybenzoyl)amino)caprylic acid and a lubricant |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4474768A (en) | 1982-07-19 | 1984-10-02 | Pfizer Inc. | N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor |
| RU2066324C1 (ru) | 1987-07-09 | 1996-09-10 | Пфайзер Инк. | Кристаллический дигидрат азитромицина и способ его получения |
| WO1989002271A1 (en) * | 1987-09-10 | 1989-03-23 | Pfizer | Azithromycin and derivatives as antiprotozoal agents |
| TW271400B (es) | 1992-07-30 | 1996-03-01 | Pfizer | |
| EP0758549A4 (en) | 1994-04-26 | 1997-07-02 | Nobuhiro Narita | MEDICAL COMPOSITION AS A MEDICINE FOR NON-SMALL CELL CANCER |
| US5605889A (en) * | 1994-04-29 | 1997-02-25 | Pfizer Inc. | Method of administering azithromycin |
| CN1096862C (zh) * | 1994-05-06 | 2002-12-25 | 辉瑞大药厂 | 阿齐霉素的控释剂型 |
| CA2302010C (en) | 1997-09-10 | 2010-11-23 | Merck & Co., Inc. | 9a-azalides as veterinary antimicrobial agents |
| US6339063B1 (en) | 1997-09-10 | 2002-01-15 | Merck & Co., Inc. | 9a-azalides as veterinary antimicrobial agents |
| CA2245398C (en) * | 1998-08-21 | 2002-01-29 | Apotex Inc. | Azithromycin monohydrate isopropanol clathrate and methods for the manufacture thereof |
| JP2002531409A (ja) * | 1998-11-30 | 2002-09-24 | テバ ファーマシューティカル インダストリーズ リミティド | アジスロマイシンのエタノール付加物、その製造方法、及びその医薬製剤 |
| FR2793690B1 (fr) * | 1999-03-30 | 2003-01-03 | Cll Pharma | Formulations pharmaceutiques en macrolides seuls ou associes a d'autres principes actifs et leur utilisation en therapeutique |
| AU2001214115A1 (en) | 2000-08-01 | 2002-02-13 | Habil F. Khorakiwala | Process for the preparation of anhydrous azithromycin |
| JP2004530703A (ja) | 2001-05-22 | 2004-10-07 | ファイザー・プロダクツ・インク | 結晶形アジスロマイシン |
| DE60232005D1 (de) * | 2001-10-18 | 2009-05-28 | Teva Pharma | Stabilisierte azithromycin-zusammensetzungen |
-
2003
- 2003-01-20 NZ NZ534234A patent/NZ534234A/en unknown
- 2003-01-20 PL PL03372394A patent/PL372394A1/xx not_active Application Discontinuation
- 2003-01-20 JP JP2003563532A patent/JP2005526020A/ja active Pending
- 2003-01-20 MX MXPA04007427A patent/MXPA04007427A/es active IP Right Grant
- 2003-01-20 KR KR1020047011565A patent/KR100676025B1/ko not_active IP Right Cessation
- 2003-01-20 EP EP03734611A patent/EP1478347A1/en not_active Withdrawn
- 2003-01-20 BR BR0307331-9A patent/BR0307331A/pt not_active IP Right Cessation
- 2003-01-20 AU AU2003201146A patent/AU2003201146B2/en not_active Ceased
- 2003-01-20 CN CNA038075105A patent/CN1646104A/zh active Pending
- 2003-01-20 CA CA002474809A patent/CA2474809A1/en not_active Abandoned
- 2003-01-20 RU RU2004123624/15A patent/RU2283092C2/ru not_active IP Right Cessation
- 2003-01-20 WO PCT/IB2003/000212 patent/WO2003063838A1/en active Application Filing
- 2003-01-28 TW TW092101816A patent/TW200306865A/zh unknown
- 2003-01-30 AR ARP030100270A patent/AR038371A1/es unknown
- 2003-01-31 US US10/355,575 patent/US7438924B2/en not_active Expired - Fee Related
-
2004
- 2004-07-21 ZA ZA200405805A patent/ZA200405805B/en unknown
- 2004-07-22 CO CO04070289A patent/CO5611118A2/es not_active Application Discontinuation
- 2004-08-31 NO NO20043644A patent/NO20043644L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| KR100676025B1 (ko) | 2007-01-29 |
| RU2004123624A (ru) | 2005-04-10 |
| CN1646104A (zh) | 2005-07-27 |
| PL372394A1 (en) | 2005-07-25 |
| RU2283092C2 (ru) | 2006-09-10 |
| US20030228357A1 (en) | 2003-12-11 |
| NZ534234A (en) | 2007-05-31 |
| TW200306865A (en) | 2003-12-01 |
| JP2005526020A (ja) | 2005-09-02 |
| BR0307331A (pt) | 2004-12-07 |
| KR20040079954A (ko) | 2004-09-16 |
| EP1478347A1 (en) | 2004-11-24 |
| WO2003063838A1 (en) | 2003-08-07 |
| CA2474809A1 (en) | 2003-08-07 |
| ZA200405805B (en) | 2006-05-31 |
| NO20043644L (no) | 2004-09-21 |
| MXPA04007427A (es) | 2004-10-11 |
| CO5611118A2 (es) | 2006-02-28 |
| US7438924B2 (en) | 2008-10-21 |
| AU2003201146B2 (en) | 2008-04-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |