AR036533A1 - Compuestos agonistas de retinoides de alquil urea, su utilizacion, composiciones farmaceuticas que los comprenden y medicamentos basados en dichos compuestos - Google Patents
Compuestos agonistas de retinoides de alquil urea, su utilizacion, composiciones farmaceuticas que los comprenden y medicamentos basados en dichos compuestosInfo
- Publication number
- AR036533A1 AR036533A1 ARP020103490A ARP020103490A AR036533A1 AR 036533 A1 AR036533 A1 AR 036533A1 AR P020103490 A ARP020103490 A AR P020103490A AR P020103490 A ARP020103490 A AR P020103490A AR 036533 A1 AR036533 A1 AR 036533A1
- Authority
- AR
- Argentina
- Prior art keywords
- alkyl
- compounds
- cycloalkyl
- hydrogen
- urea
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 5
- 239000000556 agonist Substances 0.000 title abstract 2
- 239000004202 carbamide Substances 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 5
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 3
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 3
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 3
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000012453 solvate Substances 0.000 abstract 2
- 206010014561 Emphysema Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- -1 alkyl urea Chemical compound 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000004043 oxo group Chemical group O=* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/42—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32296301P | 2001-09-18 | 2001-09-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR036533A1 true AR036533A1 (es) | 2004-09-15 |
Family
ID=33130243
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP020103490A AR036533A1 (es) | 2001-09-18 | 2002-09-16 | Compuestos agonistas de retinoides de alquil urea, su utilizacion, composiciones farmaceuticas que los comprenden y medicamentos basados en dichos compuestos |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6844466B2 (enExample) |
| EP (1) | EP1430024A1 (enExample) |
| JP (1) | JP4421293B2 (enExample) |
| KR (1) | KR100896550B1 (enExample) |
| CN (1) | CN1283621C (enExample) |
| AR (1) | AR036533A1 (enExample) |
| AU (1) | AU2002329276B2 (enExample) |
| BR (1) | BR0212583A (enExample) |
| CA (1) | CA2460693C (enExample) |
| MX (1) | MXPA04002590A (enExample) |
| PL (1) | PL370361A1 (enExample) |
| RU (1) | RU2299877C2 (enExample) |
| WO (1) | WO2003024921A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2004251712A1 (en) * | 2003-06-23 | 2005-01-06 | Auspex Pharmaceuticals, Inc. | Novel therapeautic agents for the treatment of cancer, metabolic diseases and skin disorders |
| WO2005108338A1 (en) * | 2004-05-03 | 2005-11-17 | Auspex Pharmaceuticals | Novel therapeutic agents for the treatment of cancer, metabolic diseases and skin disorders |
| CN101146763A (zh) * | 2005-03-30 | 2008-03-19 | 默克公司 | 胰高血糖素受体拮抗剂化合物、含有这种化合物的组合物以及使用方法 |
| TW200821284A (en) * | 2006-10-03 | 2008-05-16 | Merck & Co Inc | Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use |
| CN111773213B (zh) | 2010-09-01 | 2023-02-24 | 托马斯杰弗逊大学 | 用于肌肉修复和再生的组合物和方法 |
| WO2014073209A1 (ja) | 2012-11-08 | 2014-05-15 | 国立大学法人山口大学 | 角結膜障害の治療剤 |
| KR101426197B1 (ko) * | 2013-02-20 | 2014-08-01 | 여윤영 | 주먹밥틀 |
| US10702502B2 (en) | 2013-05-22 | 2020-07-07 | Yamaguchi University | Inhibitor for retinochoroidal disorders |
| CN105294567B (zh) * | 2015-10-29 | 2018-10-09 | 湖北新烯王生物科技有限公司 | 取代的3-氟苯基甲醇类化合物、药物组合物及用途 |
| ES2963348T3 (es) | 2016-06-08 | 2024-03-26 | Clementia Pharmaceuticals Inc | Métodos para tratar la osificación heterotópica |
| JP7018957B2 (ja) | 2016-11-16 | 2022-02-14 | クレメンティア ファーマシューティカルズ インコーポレイテッド | 多発性骨軟骨腫（ｍｏ）を処置するための方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LU87821A1 (fr) | 1990-10-12 | 1992-05-25 | Cird Galderma | Composes bi-aromatiques,et leur utilisation en medecine humaine et veterinaire et en cosmetique |
| DE69333894D1 (de) * | 1992-04-22 | 2005-12-01 | Ligand Pharm Inc | Verbindungen mit Retinoid x rezeptorselektivität |
| US6093742A (en) | 1997-06-27 | 2000-07-25 | Vertex Pharmaceuticals, Inc. | Inhibitors of p38 |
| JO2178B1 (en) * | 1999-10-19 | 2003-04-23 | اف . هوفمان لاروش ايه جي | Treatment of emphysema using rar selective retinoid antagonists |
-
2002
- 2002-09-11 BR BR0212583-8A patent/BR0212583A/pt not_active Application Discontinuation
- 2002-09-11 EP EP02764881A patent/EP1430024A1/en not_active Withdrawn
- 2002-09-11 MX MXPA04002590A patent/MXPA04002590A/es active IP Right Grant
- 2002-09-11 CN CNB028181522A patent/CN1283621C/zh not_active Expired - Fee Related
- 2002-09-11 JP JP2003528769A patent/JP4421293B2/ja not_active Expired - Fee Related
- 2002-09-11 CA CA2460693A patent/CA2460693C/en not_active Expired - Fee Related
- 2002-09-11 AU AU2002329276A patent/AU2002329276B2/en not_active Ceased
- 2002-09-11 WO PCT/EP2002/010179 patent/WO2003024921A1/en not_active Ceased
- 2002-09-11 RU RU2004111787/04A patent/RU2299877C2/ru not_active IP Right Cessation
- 2002-09-11 PL PL02370361A patent/PL370361A1/xx not_active IP Right Cessation
- 2002-09-11 KR KR1020047003931A patent/KR100896550B1/ko not_active Expired - Fee Related
- 2002-09-16 AR ARP020103490A patent/AR036533A1/es unknown
- 2002-09-17 US US10/245,133 patent/US6844466B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU2002329276B2 (en) | 2008-04-24 |
| BR0212583A (pt) | 2004-10-13 |
| CN1555359A (zh) | 2004-12-15 |
| MXPA04002590A (es) | 2004-06-18 |
| CA2460693C (en) | 2010-12-07 |
| JP4421293B2 (ja) | 2010-02-24 |
| RU2299877C2 (ru) | 2007-05-27 |
| PL370361A1 (en) | 2005-05-16 |
| US20030158226A1 (en) | 2003-08-21 |
| RU2004111787A (ru) | 2005-10-20 |
| WO2003024921A1 (en) | 2003-03-27 |
| CN1283621C (zh) | 2006-11-08 |
| JP2005505571A (ja) | 2005-02-24 |
| CA2460693A1 (en) | 2003-03-27 |
| US6844466B2 (en) | 2005-01-18 |
| EP1430024A1 (en) | 2004-06-23 |
| KR20040035809A (ko) | 2004-04-29 |
| KR100896550B1 (ko) | 2009-05-07 |
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