PL370361A1 - Alkyl urea retinoid agonists i - Google Patents

Alkyl urea retinoid agonists i

Info

Publication number
PL370361A1
PL370361A1 PL02370361A PL37036102A PL370361A1 PL 370361 A1 PL370361 A1 PL 370361A1 PL 02370361 A PL02370361 A PL 02370361A PL 37036102 A PL37036102 A PL 37036102A PL 370361 A1 PL370361 A1 PL 370361A1
Authority
PL
Poland
Prior art keywords
cancer
alkyl urea
emphysema
retinoid agonists
dermatological disorders
Prior art date
Application number
PL02370361A
Other languages
English (en)
Polish (pl)
Inventor
Paula Nanette Belloni
Denis John Kertesz
Michael Klaus
Jean-Marc Lapierre
Original Assignee
F.Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F.Hoffmann-La Roche Ag filed Critical F.Hoffmann-La Roche Ag
Publication of PL370361A1 publication Critical patent/PL370361A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/42Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/02Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL02370361A 2001-09-18 2002-09-11 Alkyl urea retinoid agonists i PL370361A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US32296301P 2001-09-18 2001-09-18

Publications (1)

Publication Number Publication Date
PL370361A1 true PL370361A1 (en) 2005-05-16

Family

ID=33130243

Family Applications (1)

Application Number Title Priority Date Filing Date
PL02370361A PL370361A1 (en) 2001-09-18 2002-09-11 Alkyl urea retinoid agonists i

Country Status (13)

Country Link
US (1) US6844466B2 (enExample)
EP (1) EP1430024A1 (enExample)
JP (1) JP4421293B2 (enExample)
KR (1) KR100896550B1 (enExample)
CN (1) CN1283621C (enExample)
AR (1) AR036533A1 (enExample)
AU (1) AU2002329276B2 (enExample)
BR (1) BR0212583A (enExample)
CA (1) CA2460693C (enExample)
MX (1) MXPA04002590A (enExample)
PL (1) PL370361A1 (enExample)
RU (1) RU2299877C2 (enExample)
WO (1) WO2003024921A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005000233A2 (en) * 2003-06-23 2005-01-06 Auspex Pharmaceuticals Novel therapeautic agents for the treatment of cancer, metabolic diseases and skin disorders
WO2005108338A1 (en) * 2004-05-03 2005-11-17 Auspex Pharmaceuticals Novel therapeutic agents for the treatment of cancer, metabolic diseases and skin disorders
WO2006104826A2 (en) * 2005-03-30 2006-10-05 Merck & Co., Inc. Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use
TW200821284A (en) * 2006-10-03 2008-05-16 Merck & Co Inc Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use
PL2613776T3 (pl) 2010-09-01 2021-01-11 Thomas Jefferson University Kompozycja oraz sposób naprawy i regeneracji mięśni
CN109589324B (zh) 2012-11-08 2022-06-14 国立大学法人山口大学 角结膜病症的治疗剂
KR101426197B1 (ko) * 2013-02-20 2014-08-01 여윤영 주먹밥틀
CN105377258B (zh) 2013-05-22 2020-08-28 国立大学法人山口大学 视网膜脉络膜病症的抑制剂
CN105294567B (zh) * 2015-10-29 2018-10-09 湖北新烯王生物科技有限公司 取代的3-氟苯基甲醇类化合物、药物组合物及用途
ES2963348T3 (es) 2016-06-08 2024-03-26 Clementia Pharmaceuticals Inc Métodos para tratar la osificación heterotópica
BR112019009929A2 (pt) 2016-11-16 2019-08-20 Clementia Pharmaceuticals Inc métodos para inibir a formação de um osteocondroma, para reduzir o tamanho de um osteocondroma, para desacelerar o crescimento de um osteocondroma e para reduzir hiperplasia de cartilagem

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU87821A1 (fr) 1990-10-12 1992-05-25 Cird Galderma Composes bi-aromatiques,et leur utilisation en medecine humaine et veterinaire et en cosmetique
BR9306284A (pt) * 1992-04-22 1998-01-13 Ligand Pharm Inc Compostos tendo seletividade pra receptores de retinóides x
US6093742A (en) 1997-06-27 2000-07-25 Vertex Pharmaceuticals, Inc. Inhibitors of p38
JO2178B1 (en) * 1999-10-19 2003-04-23 اف . هوفمان لاروش ايه جي Treatment of emphysema using rar selective retinoid antagonists

Also Published As

Publication number Publication date
JP4421293B2 (ja) 2010-02-24
CA2460693A1 (en) 2003-03-27
AR036533A1 (es) 2004-09-15
MXPA04002590A (es) 2004-06-18
RU2004111787A (ru) 2005-10-20
CN1555359A (zh) 2004-12-15
KR100896550B1 (ko) 2009-05-07
KR20040035809A (ko) 2004-04-29
US6844466B2 (en) 2005-01-18
CA2460693C (en) 2010-12-07
EP1430024A1 (en) 2004-06-23
AU2002329276B2 (en) 2008-04-24
JP2005505571A (ja) 2005-02-24
US20030158226A1 (en) 2003-08-21
RU2299877C2 (ru) 2007-05-27
CN1283621C (zh) 2006-11-08
WO2003024921A1 (en) 2003-03-27
BR0212583A (pt) 2004-10-13

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Legal Events

Date Code Title Description
VOID Decisions declaring the decisions on the grant of the patent lapsed