AR034251A1 - Composiciones farmaceuticas que contienen oligosacaridos, los nuevos oligosacaridos, su preparacion y su utilizacion para la preparacion de medicamentos - Google Patents

Composiciones farmaceuticas que contienen oligosacaridos, los nuevos oligosacaridos, su preparacion y su utilizacion para la preparacion de medicamentos

Info

Publication number
AR034251A1
AR034251A1 ARP010101456A ARP010101456A AR034251A1 AR 034251 A1 AR034251 A1 AR 034251A1 AR P010101456 A ARP010101456 A AR P010101456A AR P010101456 A ARP010101456 A AR P010101456A AR 034251 A1 AR034251 A1 AR 034251A1
Authority
AR
Argentina
Prior art keywords
preparation
oligosacarids
pharmaceutical compositions
new
formula
Prior art date
Application number
ARP010101456A
Other languages
English (en)
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of AR034251A1 publication Critical patent/AR034251A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C08B37/0078—Degradation products

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Immunology (AREA)
  • Polymers & Plastics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Materials Engineering (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)

Abstract

Se describen composiciones farmacéuticas que contienen como principio activo un oligosacárido de fórmula (1), en la que: n es un entero de 0 a 25; R1, R3, R4, R5, R6 y R8, idénticos o diferentes, representan un átomo de hidrógeno o un radical SO3M; R2 y R7, idénticos o diferentes, representan un átomo de hidrógeno o un radical SO3M o COCH3; y M es sodio, calcio, magnesio o potasio; o una mezcla de estos oligosacáridos, los nuevos oligosacáridos de fórmula (1), sus mezclas, sus procedimientos de preparación y la utilización de las mismas para la preparación de medicamentos. Los compuestos de fórmula (1) presentan propiedades antiinflamatorias y son útiles para la prevención y el tratamiento de enfermedades asociadas con un proceso inflamatorio que implique la producción de sustancias citotóxicas tales como el monóxido de nitrógeno.
ARP010101456A 2000-03-28 2001-03-27 Composiciones farmaceuticas que contienen oligosacaridos, los nuevos oligosacaridos, su preparacion y su utilizacion para la preparacion de medicamentos AR034251A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0003910A FR2807043B1 (fr) 2000-03-28 2000-03-28 Composition pharmaceutique contenant des oligosaccharides, les nouveaux oligosaccharides et leur preparation

Publications (1)

Publication Number Publication Date
AR034251A1 true AR034251A1 (es) 2004-02-18

Family

ID=8848572

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP010101456A AR034251A1 (es) 2000-03-28 2001-03-27 Composiciones farmaceuticas que contienen oligosacaridos, los nuevos oligosacaridos, su preparacion y su utilizacion para la preparacion de medicamentos

Country Status (27)

Country Link
EP (1) EP1272499B1 (es)
JP (1) JP2003529570A (es)
KR (1) KR20030001394A (es)
CN (1) CN1183149C (es)
AR (1) AR034251A1 (es)
AT (1) ATE290543T1 (es)
AU (1) AU782713B2 (es)
BR (1) BR0109617A (es)
CA (1) CA2403906A1 (es)
DE (1) DE60109279T2 (es)
EA (1) EA004768B1 (es)
EE (1) EE200200551A (es)
ES (1) ES2236206T3 (es)
FR (1) FR2807043B1 (es)
HK (1) HK1056564A1 (es)
HU (1) HUP0300330A3 (es)
IL (1) IL151832A0 (es)
ME (1) MEP88408A (es)
MX (1) MXPA02009455A (es)
NO (1) NO20024590L (es)
NZ (1) NZ521558A (es)
PL (1) PL204419B1 (es)
PT (1) PT1272499E (es)
SK (1) SK286745B6 (es)
WO (1) WO2001072762A1 (es)
YU (1) YU72802A (es)
ZA (1) ZA200207707B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6750207B1 (en) * 1992-05-01 2004-06-15 Yeda Research And Development Co. Ltd. Compositions for the regulation of cytokine activity
FR2845686B1 (fr) * 2002-10-10 2013-08-30 Aventis Pharma Sa Melanges de polysaccharides derives d'heparine, leur preparation et les compositions pharmaceutiques les contenant
US7511026B2 (en) * 2003-03-25 2009-03-31 Seikagaku Corporation Therapeutic agent for nerve damage
FR2857971B1 (fr) * 2003-07-24 2005-08-26 Aventis Pharma Sa Melanges d'oligosaccharides derives d'heparine, leur preparation et les compositions pharmaceutiques les contenant
US20050186679A1 (en) * 2004-02-24 2005-08-25 Christian Viskov Method for determining specific groups constituting heparins or low molecular weight heparins
JP5116071B2 (ja) 2005-07-20 2013-01-09 帝國製薬株式会社 Ｄ−アロースおよびｄ−プシコースの抗神経因性疼痛効果の利用
US8211899B2 (en) 2005-08-30 2012-07-03 Inter-University Research Institute Corporation National Institute Of Natural Sciences Artificial nucleic acid bases and their use in base pairing natural nucleic acid bases
EP3418287A1 (en) * 2017-06-21 2018-12-26 Universität für Bodenkultur Wien Chemical release of asparaginelinked glycans
CN115317507A (zh) * 2022-09-19 2022-11-11 中国科学院海洋研究所 低分子量褐藻多糖硫酸酯在制备抗多动症药物中的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5449688A (en) * 1993-03-30 1995-09-12 The United States Of America As Represented By The Department Of Health And Human Services Method of treating chronic inflammatory diseases

Also Published As

Publication number Publication date
FR2807043B1 (fr) 2002-11-22
IL151832A0 (en) 2003-04-10
DE60109279D1 (de) 2005-04-14
YU72802A (sh) 2006-01-16
EA004768B1 (ru) 2004-08-26
HK1056564A1 (en) 2004-02-20
HUP0300330A3 (en) 2003-09-29
WO2001072762A1 (fr) 2001-10-04
PL357301A1 (en) 2004-07-26
PT1272499E (pt) 2005-06-30
SK13932002A3 (sk) 2003-06-03
CN1426419A (zh) 2003-06-25
NO20024590D0 (no) 2002-09-25
AU4663901A (en) 2001-10-08
MXPA02009455A (es) 2003-02-12
CA2403906A1 (fr) 2001-10-04
JP2003529570A (ja) 2003-10-07
BR0109617A (pt) 2003-02-04
EP1272499B1 (fr) 2005-03-09
EP1272499A1 (fr) 2003-01-08
ES2236206T3 (es) 2005-07-16
SK286745B6 (sk) 2009-04-06
EA200201024A1 (ru) 2003-02-27
CN1183149C (zh) 2005-01-05
ZA200207707B (en) 2003-12-24
DE60109279T2 (de) 2006-04-13
PL204419B1 (pl) 2010-01-29
FR2807043A1 (fr) 2001-10-05
NO20024590L (no) 2002-09-25
NZ521558A (en) 2005-10-28
HUP0300330A2 (hu) 2003-06-28
ATE290543T1 (de) 2005-03-15
EE200200551A (et) 2004-04-15
MEP88408A (en) 2011-12-20
AU782713B2 (en) 2005-08-25
KR20030001394A (ko) 2003-01-06

Similar Documents

Publication Publication Date Title
AR029383A1 (es) Moleculas pequenas, los intermediarios para su sintesis, las composiciones farmaceuticas que las contienen y su uso para preparar un medicamento destinado al tratamiento o la profilaxis de enfermedades inflamatorias o mediadas por celulas inmunes
AR037517A1 (es) Derivados de naftiridinas, un proceso para su preparacion, composicion farmaceutica y el uso de los mismos para la preparacion de un medicamento para el tratamiento de una enfermedad inflamatoria
TWI262917B (en) 2-Furancarboxylic hydrazides and pharmaceutical compositions containing the same
AR029634A1 (es) Compuestos derivados heterociclicos utiles como agentes anticancerosos, composicion farmaceutica y procedimiento de tratamiento
ES2164940T3 (es) Forma de dosificacion solida bioadhesiva.
CY1117576T1 (el) Δινουκλεοτιδικα προφαρμακα
HUP0101999A2 (hu) 4-Hidroxi-kinolin-3-karboxamid- és -hidrazid-származékok, ezeket tartalmazó gyógyászati készítmények, valamint e vegyületek alkalmazása
TR200003478T2 (tr) Antikanser maddeleri olarak faydalı izotiyazol türevleri
HUP0401982A2 (hu) Indolizinszármazékok, eljárás előállításukra és a vegyületeket tartalmazó gyógyászati készítmények
PE20040949A1 (es) DERIVADOS DE HEXAHIDRO-PIRAZINO [1,2-a] PIRIMIDIN-4,7-DIONA SUSTITUIDOS EN POSICION 3 POR NITROGENO Y PROCEDIMIENTO PARA LA PREPARACION DE LA COMPOSICION FARMACEUTICA
HUP0302474A2 (hu) Terápiásan hatásos tropánszármazékok, eljárás az előállításukra, ezeket tartalmazó gyógyszerkészítmények és alkalmazásuk
AR003220A1 (es) Derivados acilados de melatonina; composicion farmaceutica y cosmetica y el uso de los mismos para la preparacion de un medicamento.
RS50829B (sr) Novi oligosaharidi, njihova proizvodnja i farmaceutske kompozicije sa sadržajem istih
AR018330A1 (es) Composiciones farmaceuticas que comprenden macrolidos como agentes activos para la terapia y profilaxis de las enfermedades de la piel
AR034251A1 (es) Composiciones farmaceuticas que contienen oligosacaridos, los nuevos oligosacaridos, su preparacion y su utilizacion para la preparacion de medicamentos
BR0208652A (pt) Composição parenteral reconstituìvel contendo um inibidor de cox-2
CL2003002565A1 (es) Compuestos derivados de 3h-quinazolin-4-ona, su proceso de preparacion, composicion farmaceutica que los contiene, y uso en el tratamiento y prevencion de enfermedades mediadas por inhibidores de mao-b, tales como la enfermedad de alzheimer y demenci
AR007108A1 (es) Agentes antitumorales y antivirales alquilantes, procedimiento para su preparacion, utilizacion de los mismos para la fabricacion de un medicamento y composicion farmaceutica que contiene a dichos agentes.
GT200100111A (es) Derivados de pirrol
CL2004000779A1 (es) Compuestos derivados de 3-azabiciclo [3.2.1]octano, composicion farmaceutica, procedimiento de preparacion, util para preparar medicamentos para tratar sindrome de intestino irritable, estrenimiento, nauseas, vomitos, disfuncion sexual, alzheimer, en
MX2009010729A (es) Derivados de dihidro-benzo[b] [1,4]diazepin-2-ona-sulfonamida.
AR003932A1 (es) Oxidiazoles procineticos, su uso como medicamento, una composicion farmaceutica que los contiene, un procedimiento para preparar dicha composicion
AR021491A1 (es) Un compuesto de 6-azauracilo que inhibe a il-5, una composicion que lo comprende, un proceso para preparar dicha composicion, y el uso de dicho compuestopara la manufactura de un medicamento y de un agente de diagnostico
ES466493A1 (es) Procedimiento de fabricacion de acidos a-aril-a -oxo-isovalericos.
HUP0204258A2 (hu) D-vitaminszármazékok alkalmazása oszteoporózis és ezzel kapcsolatos csontrendellenességek kezelésére használható gyógyászati készítmények előállítására, valamint új D3-vitaminszármazékok

Legal Events

Date Code Title Description
FB Suspension of granting procedure