AR030307A1 - Peptidos de promiostatina y metodos para utilizarlos - Google Patents

Peptidos de promiostatina y metodos para utilizarlos

Info

Publication number
AR030307A1
AR030307A1 ARP010103594A ARP010103594A AR030307A1 AR 030307 A1 AR030307 A1 AR 030307A1 AR P010103594 A ARP010103594 A AR P010103594A AR P010103594 A ARP010103594 A AR P010103594A AR 030307 A1 AR030307 A1 AR 030307A1
Authority
AR
Argentina
Prior art keywords
promiostatin
polypeptide
myostatin
peptide
domain
Prior art date
Application number
ARP010103594A
Other languages
English (en)
Spanish (es)
Original Assignee
Univ Johns Hopkins Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/628,112 external-priority patent/US7566768B1/en
Application filed by Univ Johns Hopkins Med filed Critical Univ Johns Hopkins Med
Publication of AR030307A1 publication Critical patent/AR030307A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1019Tetrapeptides with the first amino acid being basic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
ARP010103594A 2000-07-27 2001-07-27 Peptidos de promiostatina y metodos para utilizarlos AR030307A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/628,112 US7566768B1 (en) 1995-10-26 2000-07-27 Promyostatin peptides and methods of using same

Publications (1)

Publication Number Publication Date
AR030307A1 true AR030307A1 (es) 2003-08-20

Family

ID=24517522

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP010103594A AR030307A1 (es) 2000-07-27 2001-07-27 Peptidos de promiostatina y metodos para utilizarlos

Country Status (14)

Country Link
US (3) US7393682B1 (enExample)
EP (2) EP1303534A4 (enExample)
JP (1) JP5149478B2 (enExample)
CN (2) CN101261277B (enExample)
AR (1) AR030307A1 (enExample)
AU (2) AU8079901A (enExample)
BR (1) BRPI0112785B1 (enExample)
CA (1) CA2416260A1 (enExample)
IL (2) IL153970A0 (enExample)
MX (1) MXPA03000786A (enExample)
NZ (2) NZ542696A (enExample)
PL (1) PL210158B1 (enExample)
WO (1) WO2002009641A2 (enExample)
ZA (1) ZA200300483B (enExample)

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UA92504C2 (en) 2005-10-12 2010-11-10 Эли Лилли Энд Компани Anti-myostatin monoclonal antibody
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CN104761637B (zh) 2006-03-31 2021-10-15 中外制药株式会社 调控抗体血液动力学的方法
CA2693378C (en) 2006-08-03 2020-04-14 Myostin Therapeutics Pty Ltd Myostatin antagonists
PL2066695T3 (pl) * 2006-09-05 2013-08-30 Lilly Co Eli Przeciwciała przeciwko miostatynie
CN101874042B9 (zh) 2007-09-26 2019-01-01 中外制药株式会社 利用cdr的氨基酸取代来改变抗体等电点的方法
EP2275443B1 (en) 2008-04-11 2015-12-02 Chugai Seiyaku Kabushiki Kaisha Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly
JP2012021973A (ja) * 2010-06-15 2012-02-02 Nitto Denko Corp Sprセンサセルおよびsprセンサ
TWI654204B (zh) 2010-11-30 2019-03-21 Chugai Seiyaku Kabushiki Kaisha 具有鈣依存性的抗原結合能力之抗體
WO2013125667A1 (ja) 2012-02-24 2013-08-29 中外製薬株式会社 FcγRIIBを介して抗原の消失を促進する抗原結合分子
MY177331A (en) 2012-06-15 2020-09-12 Pfizer Improved antagonist antibodies against gdf-8 and uses therefor
WO2014030750A1 (ja) 2012-08-24 2014-02-27 中外製薬株式会社 マウスFcγRII特異的Fc抗体
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HUE043482T2 (hu) 2012-09-13 2019-08-28 Bristol Myers Squibb Co Miosztatint megkötõ fibronektin alapú váz domén proteinek
TWI636062B (zh) 2013-04-02 2018-09-21 中外製藥股份有限公司 Fc region variant
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HUE052232T2 (hu) 2013-05-06 2021-04-28 Scholar Rock Inc Készítmények és eljárások növekedési faktor modulálására
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WO2016125495A1 (en) 2015-02-05 2016-08-11 Chugai Seiyaku Kabushiki Kaisha Antibodies comprising an ion concentration dependent antigen-binding domain, fc region variants, il-8-binding antibodies, and uses therof
PT3922645T (pt) * 2015-09-15 2025-05-29 Scholar Rock Inc ¿anticorpos anti-pró-miostatina/miostatina latente e suas utilizações
WO2017110981A1 (en) 2015-12-25 2017-06-29 Chugai Seiyaku Kabushiki Kaisha Anti-myostatin antibodies and methods of use
ES2893813T3 (es) 2016-01-06 2022-02-10 Harvard College El tratamiento con GDF11 previene el aumento de peso, mejora la tolerancia a la glucosa y reduce la hepatoesteatosis
CN115814077A (zh) 2016-01-08 2023-03-21 供石公司 抗-原肌生长抑制素/潜伏肌生长抑制素抗体及其使用方法
KR20210082548A (ko) 2016-06-13 2021-07-05 스칼러 락, 인크. 미오스타틴 억제제의 용도 및 조합 요법
BR112019001902A2 (pt) 2016-08-05 2019-07-09 Chugai Seiyaku Kabushiki Kaisha composição para profilaxia ou tratamento de doenças relacionadas à il-8
US11155611B2 (en) 2017-01-06 2021-10-26 Scholar Rock, Inc. Compositions and methods for making and using anti-myostatin antibodies
CN111793123B (zh) * 2019-04-08 2022-03-08 中国农业大学 一种肌肉生长抑制素mstn的突变体及其应用
CN110192624A (zh) * 2019-07-05 2019-09-03 福建冠丰生物科技有限公司 一种海参牡蛎营养物口服含片及其制备方法
EP3839051A1 (en) * 2019-12-19 2021-06-23 Evonik Operations GmbH Method for the fermentative production of guanidinoacetic acid
CA3184852A1 (en) 2020-07-10 2022-01-13 Lida Katsimpardi Use of gdf11 to diagnose and treat anxiety and depression
WO2024107652A1 (en) * 2022-11-14 2024-05-23 John Mansell Myostatin inhibition
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Also Published As

Publication number Publication date
IL153970A (en) 2012-08-30
CA2416260A1 (en) 2002-02-07
EP1303534A4 (en) 2004-09-01
IL153970A0 (en) 2003-07-31
CN101261277B (zh) 2014-03-12
US20090017522A1 (en) 2009-01-15
PL365780A1 (en) 2005-01-10
CN1449409A (zh) 2003-10-15
WO2002009641A2 (en) 2002-02-07
BR0112785A (pt) 2003-07-01
ZA200300483B (en) 2004-02-19
AU8079901A (en) 2002-02-13
US8323964B2 (en) 2012-12-04
PL210158B1 (pl) 2011-12-30
JP5149478B2 (ja) 2013-02-20
WO2002009641A9 (en) 2003-03-20
MXPA03000786A (es) 2004-05-21
BRPI0112785B1 (pt) 2016-07-12
AU2001280799B2 (en) 2006-06-08
NZ523672A (en) 2006-02-24
US7393682B1 (en) 2008-07-01
EP1303534A2 (en) 2003-04-23
US20110239317A1 (en) 2011-09-29
CN101261277A (zh) 2008-09-10
WO2002009641A3 (en) 2002-05-10
JP2004504826A (ja) 2004-02-19
EP2360259A3 (en) 2011-11-16
EP2360259A2 (en) 2011-08-24
CN100429225C (zh) 2008-10-29
NZ542696A (en) 2008-02-29

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