AR023824A1 - Terapia de hiv combinacion de antagonista ccr5-interferon alfa pegilado. - Google Patents

Terapia de hiv combinacion de antagonista ccr5-interferon alfa pegilado.

Info

Publication number
AR023824A1
AR023824A1 ARP000102097A ARP000102097A AR023824A1 AR 023824 A1 AR023824 A1 AR 023824A1 AR P000102097 A ARP000102097 A AR P000102097A AR P000102097 A ARP000102097 A AR P000102097A AR 023824 A1 AR023824 A1 AR 023824A1
Authority
AR
Argentina
Prior art keywords
ccr5
antagonist
pegilado
hiv
interferon alfa
Prior art date
Application number
ARP000102097A
Other languages
English (en)
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of AR023824A1 publication Critical patent/AR023824A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Se describe el uso de un interferon-alfa pegilado, y el antagonista CCR5, adicionalmente en asociacion con por lo menos uno de ribavirina, IL-2, IL-12,pentafusida sola o en combinacion con una terapia de droga anti HIV-1, por ejemplo HAART, para la preparacion de un medicamento para el tratamiento deinfecciones de HIV-1 así como también coinfecciones de HIV-1 y HCV en pacientes adultos y pediátricos que no han sido sometidos a tratamiento, asícomo también pacientes adultos y pediátricos que hanexperimentado tratamiento.
ARP000102097A 1999-05-04 2000-05-02 Terapia de hiv combinacion de antagonista ccr5-interferon alfa pegilado. AR023824A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30489799A 1999-05-04 1999-05-04

Publications (1)

Publication Number Publication Date
AR023824A1 true AR023824A1 (es) 2002-09-04

Family

ID=23178462

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000102097A AR023824A1 (es) 1999-05-04 2000-05-02 Terapia de hiv combinacion de antagonista ccr5-interferon alfa pegilado.

Country Status (21)

Country Link
EP (1) EP1175224B1 (es)
JP (1) JP2002543144A (es)
CN (1) CN1349408A (es)
AR (1) AR023824A1 (es)
AT (1) ATE289516T1 (es)
AU (1) AU776541B2 (es)
BR (1) BR0010593A (es)
CA (1) CA2365900A1 (es)
DE (1) DE60018273T2 (es)
ES (1) ES2238277T3 (es)
HK (1) HK1039278B (es)
HU (1) HUP0202734A3 (es)
MX (1) MXPA01011116A (es)
MY (1) MY127670A (es)
NO (1) NO328679B1 (es)
NZ (1) NZ514519A (es)
PE (1) PE20010283A1 (es)
PT (1) PT1175224E (es)
TW (1) TWI289454B (es)
WO (1) WO2000066141A2 (es)
ZA (1) ZA200108870B (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050065319A1 (en) * 2000-12-19 2005-03-24 Baroudy Bahige M. Combination method for treating viral infections
TWI344955B (en) 2003-03-14 2011-07-11 Ono Pharmaceutical Co Heterocyclic rinf having nitrogen atom derivatives and medicament containing the derivatives as active ingredient
US7498323B2 (en) 2003-04-18 2009-03-03 Ono Pharmaceuticals Co., Ltd. Spiro-piperidine compounds and medicinal use thereof
JPWO2004092136A1 (ja) * 2003-04-18 2006-07-06 小野薬品工業株式会社 含窒素複素環化合物およびその用途
DE602005002673T2 (de) 2004-04-29 2008-07-24 F. Hoffmann-La Roche Ag Nukleotidsequenzvariation im Gen NS5A als Marker
PE20060598A1 (es) 2004-09-13 2006-08-21 Ono Pharmaceutical Co Derivado heterociclo conteniendo nitrogeno como antagonista de quimiocina ccr5
BRPI0609251A2 (pt) * 2005-02-23 2010-03-09 Schering Corp derivados de piperidinil piperazina úteis como inibidores de receptores de quimiocinas
EP1889622A4 (en) 2005-05-31 2009-12-23 Ono Pharmaceutical Co SPIROPIPERIDINE COMPOUND AND MEDICINAL USE THEREOF
WO2007049771A1 (ja) 2005-10-28 2007-05-03 Ono Pharmaceutical Co., Ltd. 塩基性基を含有する化合物およびその用途
ES2407115T3 (es) 2005-11-18 2013-06-11 Ono Pharmaceutical Co., Ltd. Compuesto que contiene un grupo básico y uso del mismo
EP1995246A4 (en) 2006-03-10 2010-11-17 Ono Pharmaceutical Co NITROGENATED HETEROCYCLIC DERIVATIVE AND MEDICAMENT WITH DERIVATIVE ACTIVE SUBSTANCE
JP5257068B2 (ja) 2006-05-16 2013-08-07 小野薬品工業株式会社 保護されていてもよい酸性基を含有する化合物およびその用途
US20090325992A1 (en) 2006-07-31 2009-12-31 Ono Pharmaceutical Co., Ltd. Compound having cyclic group bound thereto through spiro binding and use thereof
WO2010129351A1 (en) 2009-04-28 2010-11-11 Schepens Eye Research Institute Method to identify and treat age-related macular degeneration
US20140271680A1 (en) 2011-08-12 2014-09-18 Universite Paris-Est Creteil Val De Marne Methods and pharmaceutical compositions for treatment of pulmonary hypertension
CN106831541B (zh) 2011-11-18 2019-09-06 赫普泰雅治疗有限公司 毒蕈碱性m1受体激动剂
EP3091990B1 (en) 2014-01-08 2021-05-12 Mirror Biologics, Inc. Treatment of human immunodeficiency virus/acquired immunodeficiency syndrome
GB201519352D0 (en) 2015-11-02 2015-12-16 Heptares Therapeutics Ltd Pharmaceutical compounds
GB201617454D0 (en) 2016-10-14 2016-11-30 Heptares Therapeutics Limited Pharmaceutical compounds
GB201810239D0 (en) 2018-06-22 2018-08-08 Heptares Therapeutics Ltd Pharmaceutical compounds
GB201819960D0 (en) 2018-12-07 2019-01-23 Heptares Therapeutics Ltd Pharmaceutical compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5889006A (en) * 1995-02-23 1999-03-30 Schering Corporation Muscarinic antagonists
JP2000507917A (ja) * 1995-11-02 2000-06-27 シェーリング コーポレイション 持続的低用量サイトカイン注入治療
US5908621A (en) * 1995-11-02 1999-06-01 Schering Corporation Polyethylene glycol modified interferon therapy
GB9609932D0 (en) * 1996-05-13 1996-07-17 Hoffmann La Roche Use of IL-12 and IFN alpha for the treatment of infectious diseases
AU5522498A (en) * 1996-12-13 1998-07-03 Merck & Co., Inc. Substituted aryl piperazines as modulators of chemokine receptor activity
AR013669A1 (es) * 1997-10-07 2001-01-10 Smithkline Beecham Corp Compuestos y metodos

Also Published As

Publication number Publication date
ES2238277T3 (es) 2005-09-01
WO2000066141A3 (en) 2001-02-08
HK1039278B (zh) 2005-06-30
NO20015367D0 (no) 2001-11-02
AU776541B2 (en) 2004-09-16
EP1175224B1 (en) 2005-02-23
NO328679B1 (no) 2010-04-26
CA2365900A1 (en) 2000-11-09
JP2002543144A (ja) 2002-12-17
HK1039278A1 (en) 2002-04-19
HUP0202734A2 (hu) 2002-12-28
MXPA01011116A (es) 2002-06-04
MY127670A (en) 2006-12-29
BR0010593A (pt) 2002-02-13
ATE289516T1 (de) 2005-03-15
AU4681500A (en) 2000-11-17
TWI289454B (en) 2007-11-11
DE60018273T2 (de) 2005-08-18
DE60018273D1 (de) 2005-03-31
ZA200108870B (en) 2003-03-26
EP1175224A2 (en) 2002-01-30
WO2000066141A2 (en) 2000-11-09
NO20015367L (no) 2002-01-03
HUP0202734A3 (en) 2003-11-28
NZ514519A (en) 2003-07-25
PE20010283A1 (es) 2001-03-16
PT1175224E (pt) 2005-07-29
CN1349408A (zh) 2002-05-15

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