BR9915644A - Uso de compostos de 17-cetoesteróides e seus derivados, metabolitos e precursores no tratamento de vìrus de hepatite c e outros togavìrus - Google Patents
Uso de compostos de 17-cetoesteróides e seus derivados, metabolitos e precursores no tratamento de vìrus de hepatite c e outros togavìrusInfo
- Publication number
- BR9915644A BR9915644A BR9915644-0A BR9915644A BR9915644A BR 9915644 A BR9915644 A BR 9915644A BR 9915644 A BR9915644 A BR 9915644A BR 9915644 A BR9915644 A BR 9915644A
- Authority
- BR
- Brazil
- Prior art keywords
- compounds
- virus
- hepatitis
- treatment
- ketoesteroid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
- C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Abstract
Patente de Invenção: <B>"USO DE COMPOSTOS DE 17-CETOESTERóIDES E SEUS DERIVADOS, METABOLITOS E PRECURSORES NO TRATAMENTO DE VìRUS DE HEPATITE C E OUTROS TOGAVìRUS"<D>. A invenção provê o uso de compostos de 17-cetoesteróides, bem como derivados, metabolitos e precursores de tais compostos, e sais farmaceuticamente aceitáveis de qualquer um desses compostos, coletivamente definidos aqui os "compostos da presente invenção", no tratamento ou prevenção do vírus da hepatite do tipo C e/ou vírus da hepatite do tipo G em pacientes com necessidade de tal tratamento. Em adição, a invenção provê métodos para tratar ou prevenir infecções por togavírus, incluindo infecções por um ou mais alfavírus, flavivírus, tal como vírus da febre amarela, vírus da hepatite C, e vírus da hepatite G, vírus da rubéola ou pestivírus, tal como vírus da diarreía viral bovina. Em adição, a invenção provê terapias de combinação incluindo a administração de um ou mais compostos da presente invenção, conforme aqui definido, e administração de um ou mais compostos selecionados de compostos de aumento da concentração de plasma, fator de estimulação de macrófago, agentes de oxidação, ribavirin e interferon alfa, e/ou ventilação de oxigênio. Os compostos da presente invenção podem ser também usados para aliviar ou reduzir um ou mais sintomas associados à infecção por togavírus.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10992498P | 1998-11-24 | 1998-11-24 | |
US12408799P | 1999-03-11 | 1999-03-11 | |
US12605699P | 1999-03-23 | 1999-03-23 | |
PCT/US1999/028082 WO2000032177A2 (en) | 1998-11-24 | 1999-11-24 | Use of 17-ketosteroids in the treatment of hepatitis c virus and other togavirus infections |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9915644A true BR9915644A (pt) | 2001-08-07 |
Family
ID=27380740
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9915644-0A BR9915644A (pt) | 1998-11-24 | 1999-11-24 | Uso de compostos de 17-cetoesteróides e seus derivados, metabolitos e precursores no tratamento de vìrus de hepatite c e outros togavìrus |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP1133287A2 (pt) |
JP (1) | JP2002531397A (pt) |
KR (1) | KR20010101074A (pt) |
CN (1) | CN1328463A (pt) |
AP (1) | AP2001002181A0 (pt) |
AU (1) | AU775614B2 (pt) |
BR (1) | BR9915644A (pt) |
CA (1) | CA2352205A1 (pt) |
HK (1) | HK1042426A1 (pt) |
ID (1) | ID29864A (pt) |
IL (2) | IL142942A0 (pt) |
NZ (1) | NZ511721A (pt) |
OA (1) | OA11716A (pt) |
WO (1) | WO2000032177A2 (pt) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6667299B1 (en) | 2000-03-16 | 2003-12-23 | Hollis-Eden Pharmaceuticals, Inc. | Pharmaceutical compositions and treatment methods |
WO2001003681A2 (en) * | 1999-07-08 | 2001-01-18 | Prendergast Patrick T | Use of flavones, coumarins and related compounds to treat infections |
PT1955700E (pt) | 1999-09-30 | 2011-05-04 | Harbor Biosciences Inc | Tratamento terap?utico de doen?as associadas ao receptor de androg?nios |
JP2005535664A (ja) | 2002-07-02 | 2005-11-24 | コーセプト セラピューティクス, インコーポレイテッド | インターフェロン−α治療に関連した精神病を処置するための方法 |
CA2496867A1 (en) * | 2002-08-28 | 2004-03-11 | Hollis-Eden Pharmaceuticals, Inc. | Therapeutic treatment methods |
PT2219642E (pt) * | 2007-11-15 | 2011-10-18 | Madaus Gmbh | Componente de silibinina para o tratamento de hepatite |
CN102993148B (zh) * | 2011-09-13 | 2015-12-09 | 复旦大学 | 槲皮素衍生物或其类似物及其应用 |
WO2013178782A1 (en) * | 2012-05-30 | 2013-12-05 | Universidad De Zaragoza | Allosteric inhibitors of ns3 protease from hepatitis c virus |
CN108003212A (zh) * | 2017-12-24 | 2018-05-08 | 扬州工业职业技术学院 | 一种去氢表雄酮-6-葡萄糖苷衍生物及其作为抗丙型肝炎病毒药物的应用 |
CN110452280B (zh) * | 2019-07-25 | 2020-11-17 | 中国人民解放军第二军医大学 | 一类四环三萜酸衍生物及其制备方法与应用 |
CA3193390A1 (en) * | 2020-09-22 | 2022-03-31 | Andrey Factor | Nebulizer and nebulized anti-virals |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL194728C (nl) * | 1987-04-16 | 2003-01-07 | Hollis Eden Pharmaceuticals | Farmaceutisch preparaat geschikt voor de profylaxe of therapie van een retrovirale infectie of een complicatie of gevolg daarvan. |
US5837269A (en) * | 1989-09-25 | 1998-11-17 | University Of Utah Research Foundation | Vaccine compositions and method for enhancing an immune response |
IL126623A0 (en) * | 1996-04-17 | 1999-08-17 | Prendergast Patrick T | Pharmaceutical compositions and kits for dhea combined therapy |
WO1998047516A1 (en) * | 1997-04-17 | 1998-10-29 | Prendergast Patrick T | Combination therapy utilising 17-ketosteroids and interleukin inhibitors, or interleukin-10 potionally with interleukin inhibitors |
-
1999
- 1999-11-24 AU AU31052/00A patent/AU775614B2/en not_active Ceased
- 1999-11-24 OA OA1200100128A patent/OA11716A/en unknown
- 1999-11-24 ID IDW00200101129A patent/ID29864A/id unknown
- 1999-11-24 NZ NZ511721A patent/NZ511721A/en unknown
- 1999-11-24 IL IL14294299A patent/IL142942A0/xx active IP Right Grant
- 1999-11-24 WO PCT/US1999/028082 patent/WO2000032177A2/en not_active Application Discontinuation
- 1999-11-24 BR BR9915644-0A patent/BR9915644A/pt not_active Application Discontinuation
- 1999-11-24 CA CA002352205A patent/CA2352205A1/en not_active Abandoned
- 1999-11-24 KR KR1020017006525A patent/KR20010101074A/ko not_active Application Discontinuation
- 1999-11-24 AP APAP/P/2001/002181A patent/AP2001002181A0/en unknown
- 1999-11-24 CN CN99813658A patent/CN1328463A/zh active Pending
- 1999-11-24 JP JP2000584873A patent/JP2002531397A/ja active Pending
- 1999-11-24 EP EP99965050A patent/EP1133287A2/en not_active Withdrawn
-
2001
- 2001-05-03 IL IL142942A patent/IL142942A/en not_active IP Right Cessation
-
2002
- 2002-03-25 HK HK02102267.0A patent/HK1042426A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
WO2000032177A3 (en) | 2001-03-22 |
AU3105200A (en) | 2000-06-19 |
HK1042426A1 (zh) | 2002-08-16 |
IL142942A0 (en) | 2002-04-21 |
JP2002531397A (ja) | 2002-09-24 |
EP1133287A2 (en) | 2001-09-19 |
AP2001002181A0 (en) | 2001-05-24 |
KR20010101074A (ko) | 2001-11-14 |
IL142942A (en) | 2006-08-20 |
CA2352205A1 (en) | 2000-06-08 |
NZ511721A (en) | 2004-07-30 |
CN1328463A (zh) | 2001-12-26 |
ID29864A (id) | 2001-10-18 |
WO2000032177A2 (en) | 2000-06-08 |
OA11716A (en) | 2005-01-25 |
AU775614B2 (en) | 2004-08-05 |
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