AR021782A1 - Derivados de la 2-oxo-2h-quinoleina, un procedimiento para su preparacion, el empleo de los mismos para preparar un medicamento, las composicionesfarmaceuticas que los contienen y un procedimiento para preparar estas composiciones farmaceuticas. - Google Patents

Derivados de la 2-oxo-2h-quinoleina, un procedimiento para su preparacion, el empleo de los mismos para preparar un medicamento, las composicionesfarmaceuticas que los contienen y un procedimiento para preparar estas composiciones farmaceuticas.

Info

Publication number
AR021782A1
AR021782A1 ARP990104301A ARP990104301A AR021782A1 AR 021782 A1 AR021782 A1 AR 021782A1 AR P990104301 A ARP990104301 A AR P990104301A AR P990104301 A ARP990104301 A AR P990104301A AR 021782 A1 AR021782 A1 AR 021782A1
Authority
AR
Argentina
Prior art keywords
group
procedure
formula
derivatives
prepare
Prior art date
Application number
ARP990104301A
Other languages
English (en)
Spanish (es)
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of AR021782A1 publication Critical patent/AR021782A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • C07D215/227Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/50Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
ARP990104301A 1998-08-29 1999-08-27 Derivados de la 2-oxo-2h-quinoleina, un procedimiento para su preparacion, el empleo de los mismos para preparar un medicamento, las composicionesfarmaceuticas que los contienen y un procedimiento para preparar estas composiciones farmaceuticas. AR021782A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19839499A DE19839499A1 (de) 1998-08-29 1998-08-29 2-Oxo-2H-chinolinderivate

Publications (1)

Publication Number Publication Date
AR021782A1 true AR021782A1 (es) 2002-08-07

Family

ID=7879227

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP990104301A AR021782A1 (es) 1998-08-29 1999-08-27 Derivados de la 2-oxo-2h-quinoleina, un procedimiento para su preparacion, el empleo de los mismos para preparar un medicamento, las composicionesfarmaceuticas que los contienen y un procedimiento para preparar estas composiciones farmaceuticas.

Country Status (17)

Country Link
EP (1) EP1107954A1 (de)
JP (1) JP2002523494A (de)
KR (1) KR20010072862A (de)
CN (1) CN1315942A (de)
AR (1) AR021782A1 (de)
AU (1) AU5164199A (de)
BR (1) BR9913140A (de)
CA (1) CA2342230A1 (de)
DE (1) DE19839499A1 (de)
HK (1) HK1042478A1 (de)
HU (1) HUP0103212A3 (de)
ID (1) ID27863A (de)
NO (1) NO20010996D0 (de)
PL (1) PL346045A1 (de)
SK (1) SK2652001A3 (de)
WO (1) WO2000012479A1 (de)
ZA (1) ZA200102565B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1569912T3 (en) 2002-12-03 2015-06-29 Pharmacyclics Inc 2- (2-hydroxybiphenyl-3-yl) -1h-benzoimidazole-5-carboxamidine derivatives as factor VIIa inhibitors.
ES2896400T3 (es) 2014-08-01 2022-02-24 Nuevolution As Compuestos activos frente a bromdominios

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI59246C (fi) * 1974-06-24 1981-07-10 Otsuka Pharma Co Ltd Foerfarande foer framstaellning av benscykloamidderivat anvaendbara vid trombos- och emboliterapin
IE43079B1 (en) * 1975-03-20 1980-12-17 Ici Ltd Quinolone derivatives
JPS596858B2 (ja) * 1975-04-30 1984-02-15 オオツカセイヤク カブシキガイシヤ 3,4−ジヒドロカルボスチリル誘導体の製造法
AT347956B (de) * 1976-03-18 1979-01-25 Ici Ltd Verfahren zur herstellung von neuen chinol-2- on-4-yl-alkansaeuren und von deren basenadditionssalzen
DE2651581A1 (de) * 1976-11-12 1978-05-18 Merck Patent Gmbh Chinolonderivate und verfahren zu ihrer herstellung
AU8448491A (en) * 1990-09-07 1992-03-30 Schering Corporation Antiviral compounds and antihypertensive compounds
CA2091172C (en) * 1990-09-07 1997-05-20 Adriano Afonso Antiviral compounds and antihypertensive compounds
ZA928276B (en) * 1991-10-31 1993-05-06 Daiichi Seiyaku Co Aromatic amidine derivates and salts thereof.
DE4208304A1 (de) * 1992-03-16 1993-09-23 Merck Patent Gmbh 2-oxochinolinderivate
IL115420A0 (en) * 1994-09-26 1995-12-31 Zeneca Ltd Aminoheterocyclic derivatives
US5612353A (en) * 1995-06-07 1997-03-18 Rhone-Poulenc Rorer Pharmaceuticals Inc. Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N-[(aminoiminomethyl)phenylalkyl]-azaheterocyclylamide compounds
DE19528418A1 (de) * 1995-08-02 1997-02-06 Merck Patent Gmbh Endothelin-Rezeptor-Antagonisten
DE19530996A1 (de) * 1995-08-23 1997-02-27 Boehringer Mannheim Gmbh Cyclische Guanidine, Verfahren zu ihrer Herstellung und Arzneimittel
US5968959A (en) * 1997-12-12 1999-10-19 Orion Corporation Method for the prevention and treatment of stunned myocardium

Also Published As

Publication number Publication date
HUP0103212A3 (en) 2002-06-28
DE19839499A1 (de) 2000-03-02
NO20010996L (no) 2001-02-27
ZA200102565B (en) 2002-06-28
HK1042478A1 (zh) 2002-08-16
PL346045A1 (en) 2002-01-14
CA2342230A1 (en) 2000-03-09
CN1315942A (zh) 2001-10-03
WO2000012479A1 (de) 2000-03-09
KR20010072862A (ko) 2001-07-31
HUP0103212A2 (hu) 2002-05-29
BR9913140A (pt) 2001-05-08
SK2652001A3 (en) 2001-09-11
AU5164199A (en) 2000-03-21
ID27863A (id) 2001-04-26
JP2002523494A (ja) 2002-07-30
NO20010996D0 (no) 2001-02-27
EP1107954A1 (de) 2001-06-20

Similar Documents

Publication Publication Date Title
ES2103709T3 (es) Uso de inhibidores de peptidasa para la preparacion de medicamentos utiles en el tratamiento de la apoplejia.
KR970707069A (ko) 매트릭스 금속프로테아제 억제제로서 치환된 4-비아릴부티르산 또는 5-비아릴펜탄산 및 그의 유도체(substituted 4-biarylbutyric or 5-biarylpentanoic acids and derivatives as matrix metallorotease inhibitors)
ES2102668T3 (es) Composiciones detergentes liquidas que contienen proteasa y ciertos acidos y esteres beta-aminoalquilboronicos.
SE9203825D0 (sv) Dual inhibitors of no synthase and cyclooxygenase, process for their preparation and therapeutical compositions containing them
ES2133504T3 (es) Derivados peptidicos del acido boronico con una actividad inhibidora de proteasa, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
AR051315A1 (es) Pirimidinas 5-sustituidas inhibidoras del vih
HUP0104164A2 (hu) XA faktor inhibitor hatású imidazo[4,5-c]piridin-4-on származékok, ezeket tartalmazó gyógyászati készítmények és eljárás előállításukra
AR036187A1 (es) Un proceso para la preparacion de perindopril, compuestos analogos y sus sales, compuesto intermediario 2,5-dioxo-oxazolidina y proceso para preparar un intermediario
AR022220A1 (es) Derivados de la imidazo[4,5-c]-piridin-4-ona, un procedimiento para su preparacion, el empleo de los mismos para preparar un medicamento, los medicamentosa base de estos compuestos, las composiciones farmaceuticas que contienen estos compuestos y un procedimiento para preparar estas composiciones fa
AR021782A1 (es) Derivados de la 2-oxo-2h-quinoleina, un procedimiento para su preparacion, el empleo de los mismos para preparar un medicamento, las composicionesfarmaceuticas que los contienen y un procedimiento para preparar estas composiciones farmaceuticas.
AR035133A1 (es) Composicion topica para suministro folicular de un inhibidor de ornitina descarboxilasa
AR044175A1 (es) Compuestos de cefemo
NO954381L (no) Nye aryloksymetyloksazoliner, fremgangsmåte ved deres fremstilling og farmasöytiske preparater inneholdende dem
UY26845A1 (es) Derivados de la pirimidina
AR023496A1 (es) Derivados del dibenzoazuleno, sus enantiomeros o diastereomeros, un procedimiento para su preparacion, el empleo de los mismos como sustancias activasterapeuticas y para preparar un medicamento, las composiciones farmaceuticas que los contienen, y un procedimiento para preparar estas composicionesfa
RU2001106998A (ru) Производные 2-оксо-2н-хинолина
TH64881A (th) สารประกอบวงไพริมิดีนถูกหลอมรวมที่ถูกอัลไคนิเลทด์
ECSP003860A (es) Inhibidores no peptidicos de la union celular dependiente de vla-4 utiles en el tratamiento de enfermedades inflamatorias, autoinmunes y respiratorias
AR004401A1 (es) Derivados de la tirosina, procedimiento para prepararlos y preparaciones farmaceuticas que los contienen.