KR20010072862A - 2-옥소-2ｈ-퀴놀린 유도체 - Google Patents
2-옥소-2ｈ-퀴놀린 유도체 Download PDFInfo
- Publication number
- KR20010072862A KR20010072862A KR1020017002261A KR20017002261A KR20010072862A KR 20010072862 A KR20010072862 A KR 20010072862A KR 1020017002261 A KR1020017002261 A KR 1020017002261A KR 20017002261 A KR20017002261 A KR 20017002261A KR 20010072862 A KR20010072862 A KR 20010072862A
- Authority
- KR
- South Korea
- Prior art keywords
- methyl
- oxo
- quinoline
- amidino
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/50—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19839499A DE19839499A1 (de) | 1998-08-29 | 1998-08-29 | 2-Oxo-2H-chinolinderivate |
| DE19839499.3 | 1998-08-29 | ||
| PCT/EP1999/005315 WO2000012479A1 (de) | 1998-08-29 | 1999-07-26 | 2-oxo-2h-chinolinderivate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20010072862A true KR20010072862A (ko) | 2001-07-31 |
Family
ID=7879227
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020017002261A KR20010072862A (ko) | 1998-08-29 | 1999-07-26 | 2-옥소-2ｈ-퀴놀린 유도체 |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP1107954A1 (de) |
| JP (1) | JP2002523494A (de) |
| KR (1) | KR20010072862A (de) |
| CN (1) | CN1315942A (de) |
| AR (1) | AR021782A1 (de) |
| AU (1) | AU5164199A (de) |
| BR (1) | BR9913140A (de) |
| CA (1) | CA2342230A1 (de) |
| DE (1) | DE19839499A1 (de) |
| HK (1) | HK1042478A1 (de) |
| HU (1) | HUP0103212A3 (de) |
| ID (1) | ID27863A (de) |
| NO (1) | NO20010996L (de) |
| PL (1) | PL346045A1 (de) |
| SK (1) | SK2652001A3 (de) |
| WO (1) | WO2000012479A1 (de) |
| ZA (1) | ZA200102565B (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100513398C (zh) | 2002-12-03 | 2009-07-15 | Axys药物公司 | 作为因子viia抑制剂的2-(2-羟基联苯-3-基)-1h-苯并咪唑-5-甲脒衍生物 |
| MY187540A (en) | 2014-08-01 | 2021-09-28 | Nuevolution As | Compounds active towards bromodomains |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI59246C (fi) * | 1974-06-24 | 1981-07-10 | Otsuka Pharma Co Ltd | Foerfarande foer framstaellning av benscykloamidderivat anvaendbara vid trombos- och emboliterapin |
| IE43079B1 (en) * | 1975-03-20 | 1980-12-17 | Ici Ltd | Quinolone derivatives |
| JPS596858B2 (ja) * | 1975-04-30 | 1984-02-15 | オオツカセイヤク カブシキガイシヤ | ３，４−ジヒドロカルボスチリル誘導体の製造法 |
| AT347956B (de) * | 1976-03-18 | 1979-01-25 | Ici Ltd | Verfahren zur herstellung von neuen chinol-2- on-4-yl-alkansaeuren und von deren basenadditionssalzen |
| DE2651581A1 (de) * | 1976-11-12 | 1978-05-18 | Merck Patent Gmbh | Chinolonderivate und verfahren zu ihrer herstellung |
| EP0550464A1 (de) * | 1990-09-07 | 1993-07-14 | Schering Corporation | Anti-virale und anti-hypertensive verbindungen |
| CA2091172C (en) * | 1990-09-07 | 1997-05-20 | Adriano Afonso | Antiviral compounds and antihypertensive compounds |
| ZA928276B (en) * | 1991-10-31 | 1993-05-06 | Daiichi Seiyaku Co | Aromatic amidine derivates and salts thereof. |
| DE4208304A1 (de) * | 1992-03-16 | 1993-09-23 | Merck Patent Gmbh | 2-oxochinolinderivate |
| IL115420A0 (en) * | 1994-09-26 | 1995-12-31 | Zeneca Ltd | Aminoheterocyclic derivatives |
| US5612353A (en) * | 1995-06-07 | 1997-03-18 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N-[(aminoiminomethyl)phenylalkyl]-azaheterocyclylamide compounds |
| DE19528418A1 (de) * | 1995-08-02 | 1997-02-06 | Merck Patent Gmbh | Endothelin-Rezeptor-Antagonisten |
| DE19530996A1 (de) * | 1995-08-23 | 1997-02-27 | Boehringer Mannheim Gmbh | Cyclische Guanidine, Verfahren zu ihrer Herstellung und Arzneimittel |
| US5968959A (en) * | 1997-12-12 | 1999-10-19 | Orion Corporation | Method for the prevention and treatment of stunned myocardium |
-
1998
- 1998-08-29 DE DE19839499A patent/DE19839499A1/de not_active Withdrawn
-
1999
- 1999-07-26 AU AU51641/99A patent/AU5164199A/en not_active Abandoned
- 1999-07-26 PL PL99346045A patent/PL346045A1/xx unknown
- 1999-07-26 KR KR1020017002261A patent/KR20010072862A/ko not_active Application Discontinuation
- 1999-07-26 CA CA002342230A patent/CA2342230A1/en not_active Abandoned
- 1999-07-26 WO PCT/EP1999/005315 patent/WO2000012479A1/de not_active Application Discontinuation
- 1999-07-26 JP JP2000567512A patent/JP2002523494A/ja active Pending
- 1999-07-26 SK SK265-2001A patent/SK2652001A3/sk unknown
- 1999-07-26 EP EP99936606A patent/EP1107954A1/de not_active Withdrawn
- 1999-07-26 CN CN99810283A patent/CN1315942A/zh active Pending
- 1999-07-26 ID IDW20010680A patent/ID27863A/id unknown
- 1999-07-26 HU HU0103212A patent/HUP0103212A3/hu unknown
- 1999-07-26 BR BR9913140-4A patent/BR9913140A/pt not_active Application Discontinuation
- 1999-08-27 AR ARP990104301A patent/AR021782A1/es unknown
-
2001
- 2001-02-27 NO NO20010996A patent/NO20010996L/no not_active Application Discontinuation
- 2001-03-28 ZA ZA200102565A patent/ZA200102565B/en unknown
-
2002
- 2002-03-25 HK HK02102249.3A patent/HK1042478A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR9913140A (pt) | 2001-05-08 |
| HK1042478A1 (zh) | 2002-08-16 |
| DE19839499A1 (de) | 2000-03-02 |
| ID27863A (id) | 2001-04-26 |
| NO20010996D0 (no) | 2001-02-27 |
| CN1315942A (zh) | 2001-10-03 |
| HUP0103212A2 (hu) | 2002-05-29 |
| AU5164199A (en) | 2000-03-21 |
| PL346045A1 (en) | 2002-01-14 |
| HUP0103212A3 (en) | 2002-06-28 |
| CA2342230A1 (en) | 2000-03-09 |
| NO20010996L (no) | 2001-02-27 |
| WO2000012479A1 (de) | 2000-03-09 |
| EP1107954A1 (de) | 2001-06-20 |
| SK2652001A3 (en) | 2001-09-11 |
| AR021782A1 (es) | 2002-08-07 |
| JP2002523494A (ja) | 2002-07-30 |
| ZA200102565B (en) | 2002-06-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |