AR013817A1 - Acido nucleico, vector, procedimiento para la produccion de la glicoproteina g del virus de la rabia, glicoproteina, celulas vegetales,planta quimerica o transgenica, granos de plantas transgenicas, anticuerpos monoclonales o policlonales, composicion farmaceutica, utilizacion de la - Google Patents
Acido nucleico, vector, procedimiento para la produccion de la glicoproteina g del virus de la rabia, glicoproteina, celulas vegetales,planta quimerica o transgenica, granos de plantas transgenicas, anticuerpos monoclonales o policlonales, composicion farmaceutica, utilizacion de laInfo
- Publication number
- AR013817A1 AR013817A1 ARP970101956A ARP970101956A AR013817A1 AR 013817 A1 AR013817 A1 AR 013817A1 AR P970101956 A ARP970101956 A AR P970101956A AR P970101956 A ARP970101956 A AR P970101956A AR 013817 A1 AR013817 A1 AR 013817A1
- Authority
- AR
- Argentina
- Prior art keywords
- glicoprotein
- virus
- grains
- vector
- nucleic acid
- Prior art date
Links
- 230000009261 transgenic effect Effects 0.000 title abstract 4
- 241000700605 Viruses Species 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 108020004707 nucleic acids Proteins 0.000 title abstract 2
- 102000039446 nucleic acids Human genes 0.000 title abstract 2
- 150000007523 nucleic acids Chemical class 0.000 title abstract 2
- 239000000126 substance Substances 0.000 title 1
- 235000013311 vegetables Nutrition 0.000 title 1
- 241000711798 Rabies lyssavirus Species 0.000 abstract 3
- 108091026890 Coding region Proteins 0.000 abstract 2
- 102000003886 Glycoproteins Human genes 0.000 abstract 2
- 108090000288 Glycoproteins Proteins 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108091006027 G proteins Proteins 0.000 abstract 1
- 102000030782 GTP binding Human genes 0.000 abstract 1
- 108091000058 GTP-Binding Proteins 0.000 abstract 1
- 108010076504 Protein Sorting Signals Proteins 0.000 abstract 1
- 108010046722 Thrombospondin 1 Proteins 0.000 abstract 1
- 102100036034 Thrombospondin-1 Human genes 0.000 abstract 1
- 230000000295 complement effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 235000013305 food Nutrition 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
- C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20111—Lyssavirus, e.g. rabies virus
- C12N2760/20122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Acido nucleico, que comprende una secuencia codificadora quimérica que comprende una secuencia codificadora quimérica que comprende por una parte unasecuencia que codifica para la proteína Gmadura del virus de la rabia o de un virusrelacionad o con el virus de la rabia, o para una proteína análoga, y porotra parte, una secuencia que codifica para un péptido senal N-terminal distinto del que está naturalmente asociado con la proteína G viral, o lassecuenciascomplementarias de dic has secunecias codificadoras; vector, procedimiento para la produccion de la glicoproteína G del virus de la rabia,glicoproteína, células vegetales, planta quimérica o transgénica, granos de plantas transgénicas,anticuerpos monoclonales o policlonales, composicionfarmacéutica, utilizacion de la glicoproteína para la preparacion de un medicamento, y un producto alimenticio.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9606029A FR2748480B1 (fr) | 1996-05-09 | 1996-05-09 | Plantes transgeniques exprimant la glycoproteine g de la rage, et glycoproteines ainsi obtenues |
Publications (1)
Publication Number | Publication Date |
---|---|
AR013817A1 true AR013817A1 (es) | 2001-01-31 |
Family
ID=9492145
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP970101956A AR013817A1 (es) | 1996-05-09 | 1997-09-05 | Acido nucleico, vector, procedimiento para la produccion de la glicoproteina g del virus de la rabia, glicoproteina, celulas vegetales,planta quimerica o transgenica, granos de plantas transgenicas, anticuerpos monoclonales o policlonales, composicion farmaceutica, utilizacion de la |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0910650A1 (es) |
AR (1) | AR013817A1 (es) |
AU (1) | AU2965797A (es) |
CA (1) | CA2254115A1 (es) |
FR (1) | FR2748480B1 (es) |
WO (1) | WO1997043428A1 (es) |
ZA (1) | ZA974037B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU4994800A (en) | 1999-05-11 | 2000-11-21 | Board Of Trustees Of The University Of Illinois, The | Plant-derived antigens against respiratory syncytial virus |
US7901691B2 (en) * | 2004-08-13 | 2011-03-08 | Council Of Scientific And Indistrial Research | Chimeric G protein based rabies vaccine |
WO2008063982A2 (en) * | 2006-11-13 | 2008-05-29 | Procell Corp | High mannose glycoprotein epitopes |
WO2012171104A1 (en) | 2011-06-13 | 2012-12-20 | Medicago Inc. | Rabies virus like particle production in plants |
CN109111507B (zh) * | 2017-08-22 | 2021-12-24 | 浙江派迪畅科技发展有限公司 | 病毒重组糖蛋白及其真核细胞高效表达方法与应用 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1985001516A1 (fr) * | 1983-10-03 | 1985-04-11 | Transgene S.A. | Vecteurs d'expression d'une proteine antigenique de la rage dans les cellules eucaryotes et leur application a la preparation d'un vaccin |
NL8901932A (nl) * | 1989-07-26 | 1991-02-18 | Mogen Int | Produktie van heterologe eiwitten in planten of plantecellen. |
JPH05505525A (ja) * | 1990-03-05 | 1993-08-19 | ジ・アップジョン・カンパニー | 種子特異的調節配列類を介する蛋白発現 |
ES2235150T3 (es) * | 1990-06-15 | 2005-07-01 | Syngenta Participations Ag | Nuevas secuencias de señales. |
US5612487A (en) * | 1991-08-26 | 1997-03-18 | Edible Vaccines, Inc. | Anti-viral vaccines expressed in plants |
JPH10507916A (ja) * | 1994-10-24 | 1998-08-04 | ザ テキサス エーアンドエム ユニバーシティ システム | トランスジェニック植物による経口免疫 |
JPH08269092A (ja) * | 1995-03-31 | 1996-10-15 | Chemo Sero Therapeut Res Inst | 大腸菌組換え狂犬病ワクチン |
WO1996040229A1 (en) * | 1995-06-07 | 1996-12-19 | Thomas Jefferson University | Vaccines synthesized by transgenic plants |
-
1996
- 1996-05-09 FR FR9606029A patent/FR2748480B1/fr not_active Expired - Fee Related
-
1997
- 1997-05-07 AU AU29657/97A patent/AU2965797A/en not_active Abandoned
- 1997-05-07 CA CA002254115A patent/CA2254115A1/fr not_active Abandoned
- 1997-05-07 WO PCT/FR1997/000827 patent/WO1997043428A1/fr not_active Application Discontinuation
- 1997-05-07 EP EP97924066A patent/EP0910650A1/fr not_active Withdrawn
- 1997-05-09 ZA ZA9704037A patent/ZA974037B/xx unknown
- 1997-09-05 AR ARP970101956A patent/AR013817A1/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
ZA974037B (en) | 1998-01-08 |
WO1997043428A1 (fr) | 1997-11-20 |
FR2748480A1 (fr) | 1997-11-14 |
CA2254115A1 (fr) | 1997-11-20 |
AU2965797A (en) | 1997-12-05 |
EP0910650A1 (fr) | 1999-04-28 |
FR2748480B1 (fr) | 1998-09-04 |
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Legal Events
Date | Code | Title | Description |
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FA | Abandonment or withdrawal |