AR009122A1 - Derivados de cafalosporin pridinio, procedimiento para su preparacion, preparaciones farmaceuticas que los contienen y empleo de dichos derivados - Google Patents
Derivados de cafalosporin pridinio, procedimiento para su preparacion, preparaciones farmaceuticas que los contienen y empleo de dichos derivadosInfo
- Publication number
- AR009122A1 AR009122A1 ARP970104818A ARP970104818A AR009122A1 AR 009122 A1 AR009122 A1 AR 009122A1 AR P970104818 A ARP970104818 A AR P970104818A AR P970104818 A ARP970104818 A AR P970104818A AR 009122 A1 AR009122 A1 AR 009122A1
- Authority
- AR
- Argentina
- Prior art keywords
- derivatives
- lower alkyl
- heterocyclyl
- hydrogen
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Se refiere a derivados de cefalosporin piridinio que responden a la formula general (I), en donde: R1 es hidrogeno, alquilo inferior, cicloalquilo oacetilo; X es CH o N; n es 0, 1 o 2; m es 0 o 1; R2 es hidrogeno, alquilo inferior,omega-hidrox i, alquilo, bencilo o alquilo inferior-heterociclilo,estando el bencilo y el grupo heterociclilo insustituido o sustituido por a lo menos uno de los grupos amino, ciano, carboxilo, hidroxilo, alquilo inferior,alcoxilo inferior o-CONR2, siendo R hid rogeno o alquilo inferior; o R2 es CH2CON-R4R5, en donde R4 y R5 son independientemente hidrogeno, omega-hidroxi-alquilo, fenilo, naftilo o heterociclilo, estando el fenilo, naftilo o heterociclilo insustituido osustituido por a lo men os uno de los grupos dehidroxilo, opcionalmente protegido, halogeno, alquilo inferior opcionalmente sustituido, alcoxilo inferior opcionalmente sustituido, omega-hidroxialquiloy/o ciano; o los grupos R4 y _R5 formanconjuntamente un grupo de la fo rmula (2) con la salvedad de que m es 1, cuando el anillo de piridinilo A es unpiridinilo-4-ilo; así como sus ésteres fácilmente hidrolizables, sales farmacéuticamente aceptables de dichos compuestos ehidratos de los compuestosde formula (I) y de sus ésteres y sales. Se refiere también a un procedimiento para su preparacion, a preparaciones farmacéuticas que lascontienen y al empleo de dichos derivados.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP96116927 | 1996-10-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR009122A1 true AR009122A1 (es) | 2000-03-08 |
Family
ID=8223321
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP970104818A AR009122A1 (es) | 1996-10-22 | 1997-10-17 | Derivados de cafalosporin pridinio, procedimiento para su preparacion, preparaciones farmaceuticas que los contienen y empleo de dichos derivados |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US5935950A (es) |
| JP (1) | JP3004954B2 (es) |
| KR (1) | KR100253783B1 (es) |
| CN (1) | CN1184815A (es) |
| AR (1) | AR009122A1 (es) |
| AU (1) | AU727502B2 (es) |
| BR (1) | BR9705113A (es) |
| CA (1) | CA2214677A1 (es) |
| CO (1) | CO4910143A1 (es) |
| CZ (1) | CZ333297A3 (es) |
| HR (1) | HRP970559A2 (es) |
| HU (1) | HUP9701661A3 (es) |
| IL (1) | IL121987A0 (es) |
| MA (1) | MA24383A1 (es) |
| NO (1) | NO974759L (es) |
| NZ (1) | NZ328594A (es) |
| PE (1) | PE9999A1 (es) |
| PL (1) | PL322713A1 (es) |
| SG (1) | SG55392A1 (es) |
| TR (1) | TR199701185A2 (es) |
| TW (1) | TW446707B (es) |
| YU (1) | YU40097A (es) |
| ZA (1) | ZA979244B (es) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR0174535B1 (ko) * | 1989-09-04 | 1999-02-01 | 알렌 제이 스피글 | 베타-락탐 함유 화합물 및 그의 제조방법 |
| ATE118215T1 (de) * | 1989-09-04 | 1995-02-15 | Beecham Group Plc | Cephalosporinderivate, verfahren zu ihrer herstellung, pharmazeutische präparate und zwischenverbindungen. |
| US5523400A (en) * | 1993-04-16 | 1996-06-04 | Hoffmann-La Roche Inc. | Cephalosporin antibiotics |
| DK0620225T3 (da) * | 1993-04-16 | 2003-03-17 | Basilea Pharmaceutica Ag | Cephalosporinderivater |
-
1997
- 1997-08-20 TW TW086111934A patent/TW446707B/zh active
- 1997-08-22 NZ NZ328594A patent/NZ328594A/en unknown
- 1997-09-04 CA CA002214677A patent/CA2214677A1/en not_active Abandoned
- 1997-09-05 US US08/924,626 patent/US5935950A/en not_active Expired - Fee Related
- 1997-10-08 YU YU40097A patent/YU40097A/sh unknown
- 1997-10-09 SG SG1997003699A patent/SG55392A1/en unknown
- 1997-10-15 IL IL12198797A patent/IL121987A0/xx unknown
- 1997-10-15 ZA ZA9709244A patent/ZA979244B/xx unknown
- 1997-10-15 NO NO974759A patent/NO974759L/no not_active Application Discontinuation
- 1997-10-16 TR TR97/01185A patent/TR199701185A2/xx unknown
- 1997-10-17 MA MA24842A patent/MA24383A1/fr unknown
- 1997-10-17 JP JP9285233A patent/JP3004954B2/ja not_active Expired - Lifetime
- 1997-10-17 AR ARP970104818A patent/AR009122A1/es unknown
- 1997-10-17 HU HU9701661A patent/HUP9701661A3/hu unknown
- 1997-10-17 PE PE1997000922A patent/PE9999A1/es not_active Application Discontinuation
- 1997-10-20 CO CO97061359A patent/CO4910143A1/es unknown
- 1997-10-20 CN CN97121166A patent/CN1184815A/zh active Pending
- 1997-10-21 PL PL97322713A patent/PL322713A1/xx unknown
- 1997-10-21 AU AU42775/97A patent/AU727502B2/en not_active Ceased
- 1997-10-21 HR HR96116927.3A patent/HRP970559A2/hr not_active Application Discontinuation
- 1997-10-21 CZ CZ973332A patent/CZ333297A3/cs unknown
- 1997-10-21 KR KR1019970053950A patent/KR100253783B1/ko not_active IP Right Cessation
- 1997-10-22 BR BR9705113A patent/BR9705113A/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR100253783B1 (ko) | 2000-07-01 |
| PE9999A1 (es) | 1999-02-10 |
| CA2214677A1 (en) | 1998-04-22 |
| CZ333297A3 (cs) | 1998-05-13 |
| AU727502B2 (en) | 2000-12-14 |
| CO4910143A1 (es) | 2000-04-24 |
| NO974759D0 (no) | 1997-10-15 |
| HRP970559A2 (en) | 1998-10-31 |
| MA24383A1 (fr) | 1998-07-01 |
| YU40097A (sh) | 1999-12-27 |
| IL121987A0 (en) | 1998-03-10 |
| TR199701185A3 (tr) | 1998-05-21 |
| US5935950A (en) | 1999-08-10 |
| CN1184815A (zh) | 1998-06-17 |
| SG55392A1 (en) | 1998-12-21 |
| TW446707B (en) | 2001-07-21 |
| JPH10120687A (ja) | 1998-05-12 |
| HUP9701661A2 (hu) | 1998-11-30 |
| ZA979244B (en) | 1998-04-22 |
| NZ328594A (en) | 1998-06-26 |
| KR19980033013A (ko) | 1998-07-25 |
| AU4277597A (en) | 1998-04-30 |
| MX9707716A (es) | 1998-06-28 |
| HU9701661D0 (en) | 1997-12-29 |
| PL322713A1 (en) | 1998-04-27 |
| JP3004954B2 (ja) | 2000-01-31 |
| HUP9701661A3 (en) | 2001-04-28 |
| TR199701185A2 (xx) | 1998-05-21 |
| NO974759L (no) | 1998-04-23 |
| BR9705113A (pt) | 1998-10-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR023289A1 (es) | COMPUESTOS CON ACTIVIDAD INHIBIDORA DE ENDOPEPTIDASA NEUTRA (NEP), COMPOSICIoN FARMACÉUTICA QUE LOS CONTIENE, Y PROCEDIMIENTO PARA SU PREPARACIoN. | |
| ES2185338T3 (es) | Derivados de fumagilol y procedimientos para su fabricacion. | |
| CO4970713A1 (es) | Derivados de carboxamidotiazoles, su preparacion, composiciones farmaceuticas que los contienen | |
| AR011913A1 (es) | Derivados de 4,4-difluoro-2,3,4,5-tetrahidro-1h-1-benzoazepina y composiciones farmaceuticas de los mismos. | |
| MX9504349A (es) | Derivados de aroilpiperidina. | |
| ECSP941068A (es) | Derivados de la cefalosporina | |
| AR002711A1 (es) | Un compuesto de 2-carboxindol-3-substituido,un proceso para su preparacion, un nuevo compuesto intermediario para dicho proceso, el uso del compuesto parala fabricacion de un agente terapeutico y una composicion farmaceutica que comprende dicho compuesto. | |
| CO4990946A1 (es) | Antagonistas del receptor de trombina | |
| ES2059828T3 (es) | Un procedimiento para la preparacion de un compuesto. | |
| DK0875506T3 (da) | Quinolin- og quinazolin-forbindelser, som er anvendelige til behandling | |
| PT84424B (pt) | Processo para a preparacao de derivados de heteroaril-oxi-beta-carbolina e de composicoes farmaceuticas que os contem | |
| DK448684A (da) | Alkyldiaminderivater og deres anvendelse som laegemidler | |
| PT83726B (pt) | Processo para preparacao de derivados da beta-carbolina substituidas por grupos fenoxi e de composicoes farmaceuticas que os contem | |
| DK349287D0 (da) | (2-dimethylamino-ethyl)(2-((2-methylthio-phenyl)(phenylmethyl)amino)-2-oxo-ethyl)carbamater eller urinstofderivater, fremgangsmaade til fremstilling og anvendelse som laegemiddel af saadanne forbindelser | |
| AR009122A1 (es) | Derivados de cafalosporin pridinio, procedimiento para su preparacion, preparaciones farmaceuticas que los contienen y empleo de dichos derivados | |
| AR012249A1 (es) | Compuestos de amonio cuaternario, procedimiento para su preparacion, composicion farmaceutica que los contiene, y su uso para la preparacion de medicamentos | |
| PT99360A (pt) | Processo para a preparacao de carbamatos de oxi-sulfonilo e de composicoes farmaceuticas que os contem | |
| IT1193608B (it) | Derivati di arilossipropanolamina,procedimento per la loro preparazione composizioni farmaceutiche che li contengono e loro impiego terapeutico | |
| ES2078370T3 (es) | Procedimiento para preparar compuestos de esteres de acidos 2-halogeno-3-hidroxi-3-fenilpropionicos. | |
| SE8405430L (sv) | 7-acylindolforeningar, lempade som mellanprodukter vid synteser av 7-acylindolin-2-oner | |
| AR005454A1 (es) | Derivados de isooxacefem, su uso, procedimiento para su preparacion y preparaciones farmaceuticas que contienen a dichos derivados. | |
| GB1422806A (en) | 2,2-disubstituted benzodioxoles | |
| ECSP972291A (es) | Derivados de cepalosporin piridinio (caso rn 4410/256) | |
| GB1458321A (en) | 2,2 disubstituted-benzodioxoles | |
| PT92494A (pt) | Processo para a preparacao de novos derivados do indol |