AP388A - Inhibition of the replicateion of HIV and related viruses using thiourea derivative compounds or salts thereof. - Google Patents

Inhibition of the replicateion of HIV and related viruses using thiourea derivative compounds or salts thereof. Download PDF

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Publication number
AP388A
AP388A APAP/P/1995/000723A AP9500723A AP388A AP 388 A AP388 A AP 388A AP 9500723 A AP9500723 A AP 9500723A AP 388 A AP388 A AP 388A
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ARIPO
Prior art keywords
pyridyl
thiourea
substituted
ethyl
mmol
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APAP/P/1995/000723A
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English (en)
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AP9500723A0 (en
Inventor
Peter Thomas Lind
Jr John Michael Morin
Rolf Noreen
Robert John Ternansky
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Medivir Ab
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Publication of AP9500723A0 publication Critical patent/AP9500723A0/xx
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Publication of AP388A publication Critical patent/AP388A/en

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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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    • C07D213/72—Nitrogen atoms
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APAP/P/1995/000723A 1991-08-02 1992-07-30 Inhibition of the replicateion of HIV and related viruses using thiourea derivative compounds or salts thereof. AP388A (en)

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EP0540143B1 (de) 2003-02-05
FI923443A0 (fi) 1992-07-30
AP384A (en) 1995-05-15
WO1993003022A1 (en) 1993-02-18
ATE232095T1 (de) 2003-02-15
ZA925663B (en) 1994-01-28
AU2407492A (en) 1993-03-02
ES2051641B1 (es) 1995-10-01
RU2106341C1 (ru) 1998-03-10
ES2051641A1 (es) 1994-06-16
DE69232919D1 (de) 2003-03-13
JPH05320138A (ja) 1993-12-03
CZ228892A3 (en) 1993-05-12
DE69232919T2 (de) 2003-12-04
JP3383328B2 (ja) 2003-03-04
CZ282900B6 (cs) 1997-11-12
TW252110B (de) 1995-07-21
NO922949D0 (no) 1992-07-24

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