AP2957A - New antibodies specific of the Beta-amyloid peptides and their uses as diagnostic agents or drugs - Google Patents
New antibodies specific of the Beta-amyloid peptides and their uses as diagnostic agents or drugsInfo
- Publication number
- AP2957A AP2957A AP2010005249A AP2010005249A AP2957A AP 2957 A AP2957 A AP 2957A AP 2010005249 A AP2010005249 A AP 2010005249A AP 2010005249 A AP2010005249 A AP 2010005249A AP 2957 A AP2957 A AP 2957A
- Authority
- AP
- ARIPO
- Prior art keywords
- drugs
- beta
- antibodies specific
- diagnostic agents
- amyloid peptides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Hospice & Palliative Care (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Psychiatry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07119537 | 2007-10-29 | ||
PCT/EP2008/064432 WO2009056490A1 (en) | 2007-10-29 | 2008-10-24 | NEW ANTIBODIES SPECIFIC OF THE β-AMYLOID PEPTIDES AND THEIR USES AS DIAGNOSTIC AGENTS OR DRUGS |
Publications (2)
Publication Number | Publication Date |
---|---|
AP2010005249A0 AP2010005249A0 (en) | 2010-06-30 |
AP2957A true AP2957A (en) | 2014-08-31 |
Family
ID=38925731
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AP2010005249A AP2957A (en) | 2007-10-29 | 2008-10-24 | New antibodies specific of the Beta-amyloid peptides and their uses as diagnostic agents or drugs |
Country Status (27)
Country | Link |
---|---|
US (1) | US8343493B2 (zh) |
EP (1) | EP2205633A1 (zh) |
JP (1) | JP5421277B2 (zh) |
KR (1) | KR20100097651A (zh) |
CN (1) | CN101883792B (zh) |
AP (1) | AP2957A (zh) |
AR (1) | AR069085A1 (zh) |
AU (1) | AU2008317705B2 (zh) |
CA (1) | CA2703825A1 (zh) |
CL (1) | CL2008003197A1 (zh) |
CO (1) | CO6270369A2 (zh) |
CR (1) | CR11396A (zh) |
EA (1) | EA201070539A1 (zh) |
EC (1) | ECSP10010142A (zh) |
HN (1) | HN2010000880A (zh) |
IL (1) | IL205398A0 (zh) |
MA (1) | MA31793B1 (zh) |
MX (1) | MX2010004660A (zh) |
MY (1) | MY155144A (zh) |
NI (1) | NI201000075A (zh) |
NZ (1) | NZ585000A (zh) |
TN (1) | TN2010000197A1 (zh) |
TW (1) | TW200936605A (zh) |
UA (1) | UA103602C2 (zh) |
UY (1) | UY31433A1 (zh) |
WO (1) | WO2009056490A1 (zh) |
ZA (1) | ZA201002989B (zh) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUE033325T2 (en) * | 2007-01-05 | 2017-11-28 | Univ Zuerich | Anti-beta-amyloid binder antibodies and their use |
IL199534A (en) | 2007-01-05 | 2013-01-31 | Univ Zuerich | An isolated human antibody capable of detecting a neoepitope in a disease-related protein, a polynucleotide encoding an antibody, a vector containing the polynucleotide, a host cell containing the polynucleotide or vector, a preparation containing the antibody and related methods and uses. |
CN102317316B (zh) | 2008-12-19 | 2014-08-13 | 帕尼玛制药股份公司 | 人抗α突触核蛋白自身抗体 |
SG178953A1 (en) | 2009-09-11 | 2012-04-27 | Probiodrug Ag | Heterocylcic derivatives as inhibitors of glutaminyl cyclase |
CN102781962B (zh) | 2010-03-03 | 2014-12-10 | 阿布林克斯公司 | 双互补位A-β结合多肽 |
EP2511296A1 (en) * | 2011-04-12 | 2012-10-17 | Araclón Biotech, S. L. | Antibody, kit and method for determination of amyloid peptides |
BR112013033258B1 (pt) | 2011-06-23 | 2022-09-20 | University Of Zurich | Anticorpo isolado ou fragmento de ligação ao antígeno do mesmo que se liga a alfasinucleína, composição e seus usos |
EP2847217B1 (en) | 2012-05-10 | 2017-10-11 | Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin | CONFORMATIONAL-SPECIFIC ANTIBODIES AGAINST OLIGOMERS of Amyloid beta |
MA41115A (fr) | 2014-12-02 | 2017-10-10 | Biogen Int Neuroscience Gmbh | Procédé de traitement de la maladie d'alzheimer |
US10774120B2 (en) * | 2015-11-09 | 2020-09-15 | The University Of British Columbia | Anti-amyloid beta antibodies binding to a cyclic amyloid beta peptide |
CA3031135A1 (en) | 2016-07-18 | 2018-01-25 | The University Of British Columbia | Antibodies to amyloid beta |
JP7490211B2 (ja) | 2016-07-19 | 2024-05-27 | デューク ユニバーシティ | Cpf1に基づくゲノム編集の治療適用 |
IL272773B2 (en) | 2017-08-22 | 2024-06-01 | Biogen Ma Inc | Pharmaceutical preparations containing anti-amyloid cell antibodies |
ES2812698T3 (es) | 2017-09-29 | 2021-03-18 | Probiodrug Ag | Inhibidores de glutaminil ciclasa |
CN118382636A (zh) * | 2021-12-17 | 2024-07-23 | 豪夫迈·罗氏有限公司 | 一种用于检测淀粉样蛋白β42(Aβ42)的新抗体 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004013172A2 (en) * | 2002-07-24 | 2004-02-12 | Innogenetics N.V. | Fragments of beta-amyloid as targets for vaccination against alzheimer disease |
DE10303974A1 (de) * | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
-
2008
- 2008-10-24 EA EA201070539A patent/EA201070539A1/ru unknown
- 2008-10-24 MY MYPI2010001941A patent/MY155144A/en unknown
- 2008-10-24 EP EP08844119A patent/EP2205633A1/en not_active Withdrawn
- 2008-10-24 JP JP2010531496A patent/JP5421277B2/ja not_active Expired - Fee Related
- 2008-10-24 US US12/740,217 patent/US8343493B2/en not_active Expired - Fee Related
- 2008-10-24 AP AP2010005249A patent/AP2957A/xx active
- 2008-10-24 WO PCT/EP2008/064432 patent/WO2009056490A1/en active Application Filing
- 2008-10-24 UA UAA201006547A patent/UA103602C2/ru unknown
- 2008-10-24 AU AU2008317705A patent/AU2008317705B2/en not_active Ceased
- 2008-10-24 KR KR1020107009533A patent/KR20100097651A/ko not_active Application Discontinuation
- 2008-10-24 CA CA2703825A patent/CA2703825A1/en not_active Abandoned
- 2008-10-24 MX MX2010004660A patent/MX2010004660A/es active IP Right Grant
- 2008-10-24 CN CN200880119109.XA patent/CN101883792B/zh not_active Expired - Fee Related
- 2008-10-24 NZ NZ585000A patent/NZ585000A/xx not_active IP Right Cessation
- 2008-10-24 UY UY31433A patent/UY31433A1/es unknown
- 2008-10-27 TW TW097141147A patent/TW200936605A/zh unknown
- 2008-10-28 CL CL2008003197A patent/CL2008003197A1/es unknown
- 2008-10-28 AR ARP080104708A patent/AR069085A1/es unknown
-
2010
- 2010-04-28 HN HN2010000880A patent/HN2010000880A/es unknown
- 2010-04-28 CR CR11396A patent/CR11396A/es unknown
- 2010-04-28 IL IL205398A patent/IL205398A0/en unknown
- 2010-04-29 NI NI201000075A patent/NI201000075A/es unknown
- 2010-04-29 CO CO10050927A patent/CO6270369A2/es active IP Right Grant
- 2010-04-29 TN TN2010000197A patent/TN2010000197A1/fr unknown
- 2010-04-29 EC EC2010010142A patent/ECSP10010142A/es unknown
- 2010-04-29 ZA ZA2010/02989A patent/ZA201002989B/en unknown
- 2010-04-29 MA MA32798A patent/MA31793B1/fr unknown
Non-Patent Citations (1)
Title |
---|
'Antibodies to Beta Amyloid Proteins" INTERNET CITATION, [Online] 3 June 2002 (2002-06-03), XP002257888 Retrieved from the Internet: URL:http://web.archive.org/web/20020623071 147/www.alzforum.org/members/re sources/antibodies/Beta-Amyloid/page_set.h tml> * |
Also Published As
Publication number | Publication date |
---|---|
US8343493B2 (en) | 2013-01-01 |
HN2010000880A (es) | 2014-03-10 |
TW200936605A (en) | 2009-09-01 |
UA103602C2 (ru) | 2013-11-11 |
AR069085A1 (es) | 2009-12-30 |
CR11396A (es) | 2012-10-18 |
WO2009056490A1 (en) | 2009-05-07 |
JP2011502139A (ja) | 2011-01-20 |
CN101883792B (zh) | 2014-08-27 |
MX2010004660A (es) | 2010-07-30 |
AU2008317705B2 (en) | 2014-06-05 |
KR20100097651A (ko) | 2010-09-03 |
EA201070539A1 (ru) | 2010-10-29 |
MY155144A (en) | 2015-09-15 |
JP5421277B2 (ja) | 2014-02-19 |
IL205398A0 (en) | 2010-12-30 |
AP2010005249A0 (en) | 2010-06-30 |
NZ585000A (en) | 2012-08-31 |
CO6270369A2 (es) | 2011-04-20 |
CL2008003197A1 (es) | 2010-01-15 |
CA2703825A1 (en) | 2009-05-07 |
MA31793B1 (fr) | 2010-10-01 |
US20110059092A1 (en) | 2011-03-10 |
AU2008317705A1 (en) | 2009-05-07 |
UY31433A1 (es) | 2009-05-29 |
TN2010000197A1 (en) | 2011-11-11 |
ECSP10010142A (es) | 2010-07-30 |
ZA201002989B (en) | 2011-07-27 |
NI201000075A (es) | 2010-09-23 |
CN101883792A (zh) | 2010-11-10 |
EP2205633A1 (en) | 2010-07-14 |
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