AP2803A - Pharmaceutical composition based on kinin B2 receptor antagonists and corticosteroids, and their use - Google Patents

Pharmaceutical composition based on kinin B2 receptor antagonists and corticosteroids, and their use

Info

Publication number
AP2803A
AP2803A AP2011005572A AP2011005572A AP2803A AP 2803 A AP2803 A AP 2803A AP 2011005572 A AP2011005572 A AP 2011005572A AP 2011005572 A AP2011005572 A AP 2011005572A AP 2803 A AP2803 A AP 2803A
Authority
AP
ARIPO
Prior art keywords
kinin
corticosteroids
pharmaceutical composition
receptor antagonists
composition based
Prior art date
Application number
AP2011005572A
Other languages
English (en)
Other versions
AP2011005572A0 (en
Inventor
Sandro Giuliani
Carlo Alberto Maggi
Original Assignee
Luso Farmaco Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Luso Farmaco Inst filed Critical Luso Farmaco Inst
Publication of AP2011005572A0 publication Critical patent/AP2011005572A0/xx
Application granted granted Critical
Publication of AP2803A publication Critical patent/AP2803A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
AP2011005572A 2008-07-11 2009-07-03 Pharmaceutical composition based on kinin B2 receptor antagonists and corticosteroids, and their use AP2803A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI2008A001264A IT1391236B1 (it) 2008-07-11 2008-07-11 Composizioni farmaceutiche a base di antagonisti del recettore b2 delle chinine e corticosteroidi e loro uso
PCT/EP2009/004847 WO2010003601A1 (en) 2008-07-11 2009-07-03 Pharmaceutical compositions based on kinin b2 receptor antagonists and corticosteroids, and their use

Publications (2)

Publication Number Publication Date
AP2011005572A0 AP2011005572A0 (en) 2011-02-28
AP2803A true AP2803A (en) 2013-11-30

Family

ID=40466843

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2011005572A AP2803A (en) 2008-07-11 2009-07-03 Pharmaceutical composition based on kinin B2 receptor antagonists and corticosteroids, and their use

Country Status (36)

Country Link
US (1) US8476276B2 (ru)
EP (1) EP2303268B1 (ru)
JP (1) JP5791501B2 (ru)
KR (1) KR101656324B1 (ru)
CN (1) CN102088975B (ru)
AP (1) AP2803A (ru)
AR (1) AR072734A1 (ru)
AU (1) AU2009267416B2 (ru)
BR (1) BRPI0915866A2 (ru)
CA (1) CA2730420A1 (ru)
CO (1) CO6341556A2 (ru)
CR (1) CR20110021A (ru)
CY (1) CY1112900T1 (ru)
DK (1) DK2303268T3 (ru)
EA (1) EA019903B1 (ru)
EC (1) ECSP11010752A (ru)
ES (1) ES2389872T3 (ru)
GE (1) GEP20135792B (ru)
HK (1) HK1158547A1 (ru)
HN (1) HN2011000089A (ru)
HR (1) HRP20120678T1 (ru)
IL (1) IL210554A0 (ru)
IT (1) IT1391236B1 (ru)
MA (1) MA32542B1 (ru)
MX (1) MX2011000350A (ru)
MY (1) MY150477A (ru)
NI (1) NI201100014A (ru)
NZ (1) NZ590427A (ru)
PL (1) PL2303268T3 (ru)
PT (1) PT2303268E (ru)
RS (1) RS52418B (ru)
SI (1) SI2303268T1 (ru)
TW (1) TWI499419B (ru)
UA (1) UA100060C2 (ru)
WO (1) WO2010003601A1 (ru)
ZA (1) ZA201100287B (ru)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120190653A1 (en) * 2011-01-20 2012-07-26 Dow Pharmaceutical Sciences, Inc. Therapeutic eye drop comprising doxycycline and a stabilizer
RU2015138443A (ru) * 2013-03-14 2017-04-20 Шир Хьюман Дженетик Терапис, Инк. Способы лечения ангионевротического отека, опосредованного рецепторами брадикинина в2
CN104072585A (zh) * 2014-07-21 2014-10-01 成都圣诺生物科技股份有限公司 一种合成艾替班特的方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003000696A1 (en) * 2001-06-26 2003-01-03 Metaphore Pharmaceuticals, Inc. COMBINATION THERAPY OF AN SODm AND A CORTICOSTEROID FOR PREVENTION AND/OR TREATMENT OF INFLAMMATORY DISEASE
WO2004069266A2 (de) * 2003-02-07 2004-08-19 Aventis Pharma Deutschland Gmbh Die verwendung von antagonisten des bradykinin-b2 rezeptors zur behandlung von osteoarthrose
WO2006040004A1 (en) * 2004-10-15 2006-04-20 Istituto Luso Farmaco D'italia S.P.A. Non-peptide bradykinin antagonists and pharmaceutical compositions therefrom
WO2007003411A2 (en) * 2005-07-05 2007-01-11 Jerini Ag Kinin antagonists for treating bladder dysfunction
EP1894559A1 (en) * 2006-09-01 2008-03-05 PARI Pharma GmbH Means to solubilise steroids for inhalation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20021247A1 (it) * 2002-06-07 2003-12-09 Menarini Ricerche Spa Antagonisti basici non peptidici della bradichinina e loro impiego informulazioni farmaceutiche

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003000696A1 (en) * 2001-06-26 2003-01-03 Metaphore Pharmaceuticals, Inc. COMBINATION THERAPY OF AN SODm AND A CORTICOSTEROID FOR PREVENTION AND/OR TREATMENT OF INFLAMMATORY DISEASE
WO2004069266A2 (de) * 2003-02-07 2004-08-19 Aventis Pharma Deutschland Gmbh Die verwendung von antagonisten des bradykinin-b2 rezeptors zur behandlung von osteoarthrose
WO2006040004A1 (en) * 2004-10-15 2006-04-20 Istituto Luso Farmaco D'italia S.P.A. Non-peptide bradykinin antagonists and pharmaceutical compositions therefrom
WO2007003411A2 (en) * 2005-07-05 2007-01-11 Jerini Ag Kinin antagonists for treating bladder dysfunction
EP1894559A1 (en) * 2006-09-01 2008-03-05 PARI Pharma GmbH Means to solubilise steroids for inhalation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SHARMA, JAGDISH N. ET AL: "Inhibition of rats adjuvant arthritis by a bradykinin antagonist Hoe 140 and its influence on kallikreins" GENERAL PHARMACOLOGY , 27(1), 133-6 CODEN: GEPHDP; ISSN: 0306-3623, 1996, XP008105253 *

Also Published As

Publication number Publication date
EP2303268A1 (en) 2011-04-06
CA2730420A1 (en) 2010-01-14
MY150477A (en) 2014-01-30
NI201100014A (es) 2011-09-13
NZ590427A (en) 2012-09-28
AU2009267416B2 (en) 2013-09-12
ZA201100287B (en) 2012-03-28
UA100060C2 (ru) 2012-11-12
TWI499419B (zh) 2015-09-11
AP2011005572A0 (en) 2011-02-28
GEP20135792B (en) 2013-03-25
HN2011000089A (es) 2013-01-28
DK2303268T3 (da) 2012-07-23
KR20110044970A (ko) 2011-05-03
CO6341556A2 (es) 2011-11-21
ECSP11010752A (es) 2011-04-29
SI2303268T1 (sl) 2012-10-30
CY1112900T1 (el) 2016-04-13
MX2011000350A (es) 2011-02-22
BRPI0915866A2 (pt) 2015-11-03
CR20110021A (es) 2011-07-11
WO2010003601A8 (en) 2010-03-18
ES2389872T3 (es) 2012-11-02
IL210554A0 (en) 2011-03-31
JP2011527296A (ja) 2011-10-27
PL2303268T3 (pl) 2012-11-30
AR072734A1 (es) 2010-09-15
CN102088975B (zh) 2013-08-21
TW201006471A (en) 2010-02-16
HRP20120678T1 (hr) 2012-09-30
EA019903B1 (ru) 2014-07-30
US8476276B2 (en) 2013-07-02
ITMI20081264A1 (it) 2010-01-12
US20110112011A1 (en) 2011-05-12
CN102088975A (zh) 2011-06-08
AU2009267416A1 (en) 2010-01-14
KR101656324B1 (ko) 2016-09-09
IT1391236B1 (it) 2011-12-01
EP2303268B1 (en) 2012-06-20
WO2010003601A1 (en) 2010-01-14
MA32542B1 (fr) 2011-08-01
JP5791501B2 (ja) 2015-10-07
HK1158547A1 (en) 2012-07-20
EA201100013A1 (ru) 2011-08-30
RS52418B (en) 2013-02-28
PT2303268E (pt) 2012-09-24

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