AP2353A - 3- or 4-monosubstituted phenol and thiophenol derivatives useful as H3 ligands. - Google Patents

3- or 4-monosubstituted phenol and thiophenol derivatives useful as H3 ligands.

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Publication number
AP2353A
AP2353A AP2006003772A AP2006003772A AP2353A AP 2353 A AP2353 A AP 2353A AP 2006003772 A AP2006003772 A AP 2006003772A AP 2006003772 A AP2006003772 A AP 2006003772A AP 2353 A AP2353 A AP 2353A
Authority
AP
ARIPO
Prior art keywords
ligands
derivatives useful
thiophenol derivatives
monosubstituted phenol
monosubstituted
Prior art date
Application number
AP2006003772A
Other languages
English (en)
Other versions
AP2006003772A0 (en
Inventor
Patrick Bernardelli
Andrew Michael Cronin
Alexis Denis
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP04291187A external-priority patent/EP1593679A1/fr
Priority claimed from GB0504564A external-priority patent/GB0504564D0/en
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of AP2006003772A0 publication Critical patent/AP2006003772A0/xx
Application granted granted Critical
Publication of AP2353A publication Critical patent/AP2353A/xx

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AP2006003772A 2004-05-07 2005-04-19 3- or 4-monosubstituted phenol and thiophenol derivatives useful as H3 ligands. AP2353A (en)

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Application Number Priority Date Filing Date Title
EP04291187A EP1593679A1 (fr) 2004-05-07 2004-05-07 Dérivés de phénol 3- ou 4-monosubstitués utiles comme ligands de H3
GB0504564A GB0504564D0 (en) 2005-03-04 2005-03-04 New compounds
PCT/IB2005/001114 WO2005108384A1 (fr) 2004-05-07 2005-04-19 Derives de phenol et de thiophenol 3- ou 4-monosubstitues utiles en tant que ligands h3

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AP2006003772A0 AP2006003772A0 (en) 2006-10-31
AP2353A true AP2353A (en) 2012-02-16

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CA2614282A1 (fr) 2005-07-06 2007-01-11 Sepracor Inc. Combinaisons d'eszopiclone et de trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-n-methyl-1-naphtalenamine or trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphtalenamine, et methodes de traitement de la menopause et des troubles de l'humeur, de l'anxiete et troubles cognitifs
WO2007045989A1 (fr) * 2005-10-20 2007-04-26 Pfizer Limited Dérivés de pyridyle pouvant être employés en tant que ligands h3
US8053603B2 (en) 2006-01-06 2011-11-08 Sunovion Pharmaceuticals Inc. Tetralone-based monoamine reuptake inhibitors
KR101294014B1 (ko) 2006-01-06 2013-08-09 선오비온 파마슈티컬스 인코포레이티드 모노아민 재흡수 저해제로서의 시클로알킬아민
PT2816024T (pt) 2006-03-31 2017-10-20 Sunovion Pharmaceuticals Inc Aminas quirais
AU2007236115A1 (en) 2006-04-11 2007-10-18 Novartis Ag Organic compounds
CN103382174A (zh) * 2006-06-23 2013-11-06 雅培制药有限公司 作为组胺h3受体调节物的环丙胺衍生物
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RU2470011C2 (ru) 2007-05-31 2012-12-20 Сепракор Инк. Циклоалкиламины, содержащие в качестве заместителя фенил, как ингибиторы обратного захвата моноаминов
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US9186353B2 (en) 2009-04-27 2015-11-17 Abbvie Inc. Treatment of osteoarthritis pain
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WO2012037258A1 (fr) 2010-09-16 2012-03-22 Abbott Laboratories Procédés de préparation de dérivés cyclopropyliques substitués en 1,2
PE20141682A1 (es) * 2011-10-26 2014-11-14 Pfizer Ltd Derivados de (4-fenilimidazol-2-il) etilamina utiles como moduladores de canal de sodio
WO2014095534A1 (fr) * 2012-12-19 2014-06-26 Basf Se Nouveaux triazoles et imidazoles substitués et leur utilisation en tant que fongicides
PT3309150T (pt) * 2013-01-09 2021-08-31 Arena Pharm Inc Ácido (r)-3-(4'-(2-(2-metilpirrolidin-1-il)etil)bifenil-4-il)propanoico como moduladores do recetor de histamina h3 para o tratamento de distúrbios cognitivos
TWI663159B (zh) 2013-12-10 2019-06-21 美商健臻公司 原肌球蛋白相關之激酶（ｔｒｋ）抑制劑
CN110950862B (zh) 2014-12-18 2024-01-05 建新公司 原肌球蛋白相关激酶(trk)抑制剂的药物制剂
CN113336715B (zh) * 2021-08-04 2021-11-23 山东海利尔化工有限公司 一种含二氧戊环的三唑类化合物及其中间体的制备方法

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WO2002076925A2 (fr) * 2001-03-23 2002-10-03 Eli Lilly And Company Composes d'aryl alkylamines non imidazole comme antagonistes des recepteurs h3 de l'histamine, preparation et applications therapeutiques

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WO2002006223A1 (fr) * 2000-07-13 2002-01-24 Abbott Laboratories Pyrrolidines 1,3-disubstituees et 1,3,3-trisubstituees utilisees comme ligands du recepteur de l'histamine-3 et leurs applications therapeutiques
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Publication number Priority date Publication date Assignee Title
EP2514743A1 (fr) 2003-05-19 2012-10-24 Irm Llc Composés d'immunosuppression et compositions

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