AP2188A - Substituted quinolines and their use as mycobacterial inhibitors. - Google Patents

Substituted quinolines and their use as mycobacterial inhibitors.

Info

Publication number
AP2188A
AP2188A AP2006003693A AP2006003693A AP2188A AP 2188 A AP2188 A AP 2188A AP 2006003693 A AP2006003693 A AP 2006003693A AP 2006003693 A AP2006003693 A AP 2006003693A AP 2188 A AP2188 A AP 2188A
Authority
AP
ARIPO
Prior art keywords
substituted quinolines
mycobacterial inhibitors
mycobacterial
inhibitors
quinolines
Prior art date
Application number
AP2006003693A
Other languages
English (en)
Other versions
AP2006003693A0 (en
Inventor
Jerome Emile Georges Guillemont
Elisabeth Therese Jeanne Pasquier
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of AP2006003693A0 publication Critical patent/AP2006003693A0/xx
Application granted granted Critical
Publication of AP2188A publication Critical patent/AP2188A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5355—Non-condensed oxazines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AP2006003693A 2004-01-23 2005-01-21 Substituted quinolines and their use as mycobacterial inhibitors. AP2188A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53876804P 2004-01-23 2004-01-23
PCT/EP2005/050267 WO2005070924A1 (en) 2004-01-23 2005-01-21 Substituted quinolines and their use as mycobacterial inhibitors

Publications (2)

Publication Number Publication Date
AP2006003693A0 AP2006003693A0 (en) 2006-08-31
AP2188A true AP2188A (en) 2010-12-14

Family

ID=34807224

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2006003693A AP2188A (en) 2004-01-23 2005-01-21 Substituted quinolines and their use as mycobacterial inhibitors.

Country Status (20)

Country Link
US (1) US7338949B2 (de)
EP (1) EP1711492B1 (de)
JP (1) JP4773975B2 (de)
KR (1) KR101150172B1 (de)
CN (1) CN1910177B (de)
AP (1) AP2188A (de)
AT (1) ATE392423T1 (de)
AU (1) AU2005206330B2 (de)
BR (1) BRPI0507076B8 (de)
CA (1) CA2553266C (de)
DE (1) DE602005006101T2 (de)
EA (1) EA011359B1 (de)
ES (1) ES2306082T3 (de)
HK (1) HK1100927A1 (de)
IL (1) IL177013A0 (de)
NO (1) NO337705B1 (de)
NZ (1) NZ547277A (de)
UA (1) UA85570C2 (de)
WO (1) WO2005070924A1 (de)
ZA (1) ZA200606070B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2554049C (en) * 2004-01-29 2012-12-18 Janssen Pharmaceutica N.V. Quinoline derivatives for use as mycobacterial inhibitors
EE05697B1 (et) * 2005-06-08 2014-02-17 Janssen Pharmaceutica N.V. Kinoliini derivaadid kui antibakteriaalsed toimeained
JO2837B1 (en) * 2005-08-03 2014-09-15 جانسن فارمسيتكا ان في Quinoline derivatives acting as antibacterial agents
JO2855B1 (en) 2005-08-03 2015-03-15 شركة جانسين فارماسوتيكا ان. في Quinoline derivatives acting as antibacterial agents
EP1917245A1 (de) 2005-08-21 2008-05-07 Abbott GmbH & Co. KG Heterocyclische verbindungen und ihre verwendung als bindungspartner für 5-ht5-rezeptoren
JO2684B1 (en) * 2006-12-06 2013-03-03 جانسين فارماسوتيكا ان في Quinoline antibacterial derivatives
JO2685B1 (en) 2006-12-06 2013-03-03 جانسين فارماسوتيكا ان في Quinoline antibacterial derivatives
JO3271B1 (ar) 2006-12-06 2018-09-16 Janssen Pharmaceutica Nv مشتقات الكوينولين المضادة للجراثيم
JO2970B1 (en) 2006-12-06 2016-03-15 جانسين فارماسوتيكا ان. في Quinoline antibacterial derivatives
WO2009091324A1 (en) * 2008-01-14 2009-07-23 Jyoti Chattopadhyaya Quinoline, naphthalene and conformationally constrained quinoline or naphthalene derivates as anti-mycobacterial agents
WO2013160431A1 (en) * 2012-04-27 2013-10-31 Janssen Pharmaceutica Nv Antibacterial quinoline derivatives
CA2869718C (en) * 2012-04-27 2021-05-11 Janssen Pharmaceutica Nv Antibacterial quinoline derivatives
BR112017023448A2 (pt) * 2015-04-29 2018-07-31 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) composições anti-fitopatogênicas

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965572A (en) * 1996-10-28 1999-10-12 The United States Of America As Respresented By The Secretary Of The Army Methods for treating antibiotic-resistant infections
WO2000034265A2 (en) * 1998-12-11 2000-06-15 Sepracor, Inc. Quinoline-indole antimicrobial agents

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100525766C (zh) * 1997-06-02 2009-08-12 詹森药业有限公司 用作平滑肌细胞增殖抑制剂的（咪唑-5-基）甲基-2-喹啉酮衍生物
EP0991623A2 (de) * 1997-06-19 2000-04-12 Sepracor, Inc. Chinolin-indol verbindungen mit antimikrobieller wirkung
US6838467B2 (en) * 2000-02-24 2005-01-04 Janssen Pharmaceutica N. V. Dosing regimen
EE05195B1 (et) * 2000-10-02 2009-08-17 Janssen Pharmaceutica N.V. Kinoliini ja kinolinooni derivaadid glutamaatretseptori antagonistidena, nende saamine ja kasutamine ravimite valmistamiseks ning neid sisaldav farmatseutiline kompositsioon
MXPA05001052A (es) * 2002-07-25 2005-04-08 Janssen Pharmaceutica Nv Derivados de quinolina y su uso como inhibidores micobacterianos.

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965572A (en) * 1996-10-28 1999-10-12 The United States Of America As Respresented By The Secretary Of The Army Methods for treating antibiotic-resistant infections
WO2000034265A2 (en) * 1998-12-11 2000-06-15 Sepracor, Inc. Quinoline-indole antimicrobial agents

Also Published As

Publication number Publication date
BRPI0507076B8 (pt) 2021-05-25
CN1910177A (zh) 2007-02-07
NZ547277A (en) 2009-08-28
DE602005006101D1 (de) 2008-05-29
WO2005070924A1 (en) 2005-08-04
KR101150172B1 (ko) 2012-05-25
CN1910177B (zh) 2010-05-05
AU2005206330B2 (en) 2010-09-16
CA2553266A1 (en) 2005-08-04
KR20060127016A (ko) 2006-12-11
ZA200606070B (en) 2007-12-27
BRPI0507076B1 (pt) 2019-06-25
US7338949B2 (en) 2008-03-04
DE602005006101T2 (de) 2009-07-02
UA85570C2 (uk) 2009-02-10
EA200601363A1 (ru) 2006-12-29
ES2306082T3 (es) 2008-11-01
HK1100927A1 (en) 2007-10-05
CA2553266C (en) 2013-03-12
ATE392423T1 (de) 2008-05-15
EP1711492A1 (de) 2006-10-18
BRPI0507076A (pt) 2007-06-19
JP4773975B2 (ja) 2011-09-14
NO20063747L (no) 2006-08-22
JP2007518775A (ja) 2007-07-12
EP1711492B1 (de) 2008-04-16
EA011359B1 (ru) 2009-02-27
AP2006003693A0 (en) 2006-08-31
IL177013A0 (en) 2006-12-10
WO2005070924A8 (en) 2006-05-11
AU2005206330A1 (en) 2005-08-04
NO337705B1 (no) 2016-06-06
US20070082895A1 (en) 2007-04-12

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