AP2005003238A0 - Novel benzoimidazole derivatives useful as antiproliferative agents. - Google Patents

Novel benzoimidazole derivatives useful as antiproliferative agents.

Info

Publication number
AP2005003238A0
AP2005003238A0 AP2005003238A AP2005003238A AP2005003238A0 AP 2005003238 A0 AP2005003238 A0 AP 2005003238A0 AP 2005003238 A AP2005003238 A AP 2005003238A AP 2005003238 A AP2005003238 A AP 2005003238A AP 2005003238 A0 AP2005003238 A0 AP 2005003238A0
Authority
AP
ARIPO
Prior art keywords
derivatives useful
antiproliferative agents
benzoimidazole derivatives
novel benzoimidazole
novel
Prior art date
Application number
AP2005003238A
Other languages
English (en)
Inventor
John Charles Kath
Joseph Peter Lyssikatos
Huifen Faye Wang
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of AP2005003238A0 publication Critical patent/AP2005003238A0/xx

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    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/0225Spirochetes, e.g. Treponema, Leptospira, Borrelia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
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    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/155Paramyxoviridae, e.g. parainfluenza virus
    • AHUMAN NECESSITIES
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    • A61K39/245Herpetoviridae, e.g. herpes simplex virus
    • A61K39/265Infectious rhinotracheitis virus
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    • A61P31/04Antibacterial agents
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AP2005003238A 2002-08-26 2003-08-14 Novel benzoimidazole derivatives useful as antiproliferative agents. AP2005003238A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40596902P 2002-08-26 2002-08-26
PCT/IB2003/003633 WO2004017990A1 (en) 2002-08-26 2003-08-14 Vaccine for respiratory and reproductive system infections in cattle

Publications (1)

Publication Number Publication Date
AP2005003238A0 true AP2005003238A0 (en) 2005-03-31

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AP2005003238A AP2005003238A0 (en) 2002-08-26 2003-08-14 Novel benzoimidazole derivatives useful as antiproliferative agents.

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US (4) US20040081666A1 (is)
EP (2) EP1743652B1 (is)
JP (4) JP2006501237A (is)
KR (2) KR20050062542A (is)
CN (1) CN1315534C (is)
AP (1) AP2005003238A0 (is)
AR (1) AR041047A1 (is)
AT (1) ATE533506T1 (is)
AU (2) AU2003263390B2 (is)
BR (1) BR0313806A (is)
CA (1) CA2496750C (is)
EA (1) EA011578B1 (is)
GT (1) GT200300180A (is)
HK (1) HK1078457A1 (is)
HR (2) HRP20050192B1 (is)
IS (1) IS7672A (is)
MA (1) MA27388A1 (is)
ME (1) ME00810B (is)
MX (1) MXPA05002255A (is)
NO (1) NO20050603L (is)
NZ (2) NZ565206A (is)
OA (1) OA12915A (is)
PA (1) PA8581101A1 (is)
PE (1) PE20040420A1 (is)
PL (1) PL216541B1 (is)
RS (1) RS20050177A (is)
TN (1) TNSN05059A1 (is)
TW (1) TWI272105B (is)
UA (1) UA94689C2 (is)
UY (1) UY27948A1 (is)
WO (1) WO2004017990A1 (is)
ZA (1) ZA200501171B (is)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7179473B2 (en) 1998-06-05 2007-02-20 Boehringer Ingelheim Vetmedica Gmbh Attenuated pestiviruses
US7135561B2 (en) 2001-09-06 2006-11-14 Boehringer Ingelheim Vetmedica Gmbh Infectious bovine viral diarrhea virus clone
CA2496750C (en) * 2002-08-26 2014-10-21 Pfizer Products Inc. Vaccine for respiratory and reproductive system infections in cattle
US20050089533A1 (en) * 2003-01-29 2005-04-28 Joseph Frantz Canine vaccines against Bordetella bronchiseptica
US7563449B2 (en) * 2003-04-21 2009-07-21 Pfizer Inc, Methods for reducing cattle reproductive diseases
US7361357B2 (en) * 2003-07-29 2008-04-22 Pfizer Inc. Safe mutant viral vaccines
WO2005058356A2 (en) 2003-12-17 2005-06-30 Wyeth Methods for porducing storage stable viruses and immunogenic compositions thereof
JP5393978B2 (ja) * 2004-04-05 2014-01-22 ゾエティス・ピー・エルエルシー マイクロ流動化された水中油型乳剤及びワクチン組成物
US7572455B2 (en) * 2004-05-19 2009-08-11 Boehringer Ingelheim Vetmedica Gmbh Vaccine comprising an attenuated pestivirus
UY29915A1 (es) * 2005-11-15 2007-06-29 Boehringer Ingelheim Vetmed Vacuna combinada que comprende un virus atenuado de la diarrea viral bovina
EP2377550B1 (en) 2006-09-11 2015-03-04 Zoetis P LLC Heat treated bacterins, and emulsion vaccines prepared from such heat treated bacterins
WO2008036747A2 (en) * 2006-09-21 2008-03-27 Amarillo Biosciences, Inc. Composition and method for immunomodulation
US7803527B2 (en) * 2007-10-31 2010-09-28 Novartis Ag Inactivated bovine herpes virus-1 and methods
DK2224951T3 (da) * 2007-12-21 2020-01-06 Zoetis Services Llc Varmebehandlede bakteriner og emulsionsvacciner, der er fremstillet af sådanne varmebehandlede bakteriner
UY31930A (es) * 2008-06-25 2010-01-29 Boheringer Ingelheim Pharma Kg Pestivirus atenuados recombinantes, en particular a csfv, bvdv o bdv atenuado recombinante
BRPI0920800A2 (pt) 2008-10-03 2020-08-11 Novartis Ag vírus da herpes bovina-1, composição, método para produzir uma resposta imunológica em um hospedeiro, e, uso de vírus da herpes bovina-1.
US8846054B2 (en) * 2009-01-09 2014-09-30 Boehringer Ingelheim Vetmedica, Inc. Method of treating pregnant cows and/or heifers
CA2836805C (en) * 2011-06-10 2023-03-07 Novartis Ag Bovine vaccines and methods
RU2522780C2 (ru) * 2012-07-27 2014-07-20 Государственное научное учреждение Всероссийский научно-исследовательский институт ветеринарной санитарии, гигиены и экологии Российской академии сельскохозяйственных наук Способ получения вакцины против инфекционного ринотрахеита крупного рогатого скота
US9314519B2 (en) 2012-08-21 2016-04-19 Intervet Inc. Liquid stable virus vaccines
US20140147475A1 (en) 2012-11-29 2014-05-29 Antonius Arnoldus Christiaan Jacobs Vaccine to protect a ruminant against pneumonia caused by pasteurella multocida
US9393298B2 (en) 2013-03-15 2016-07-19 Intervet Inc. Liquid stable bovine virus vaccines
US9480739B2 (en) * 2013-03-15 2016-11-01 Intervet Inc. Bovine virus vaccines that are liquid stable
MX357432B (es) 2013-03-18 2018-07-09 Intervet Int Bv Vacuna para proteger a un rumiante contra la neumonia causada por mannheimia haemolytica.
AR097762A1 (es) 2013-09-27 2016-04-13 Intervet Int Bv Formulaciones secas de vacunas que son estables a temperatura ambiente
AR099470A1 (es) 2014-02-17 2016-07-27 Intervet Int Bv Vacunas de virus de aves de corral líquidas
TWI670085B (zh) 2014-02-19 2019-09-01 荷蘭商英特威國際公司 液體穩定之豬病毒疫苗
CA3010977A1 (en) 2016-01-11 2017-07-20 Zoetis Services Llc Novel cross protective vaccine compositions for porcine epidemic diarrhea virus
BR112018069371A2 (pt) 2016-03-21 2019-01-22 South Dakota Board Of Regents construção de ácido nucleico, vetor, vacina ou composição imunogênica, método de entrega de uma vacina, método de produção de uma construção de ácido nucleico e método para conferir imunidade contra um antígeno
BR112019006900A2 (pt) 2016-10-05 2019-07-02 Zoetis Services Llc métodos de liofilização que proporcionam protozoários desidratados estáveis para o uso como potentes vacinas vivas
RU2643335C1 (ru) * 2016-11-14 2018-01-31 Федеральное государственное бюджетное образовательное учреждение высшего образования Санкт-Петербургская государственная академия ветеринарной медицины (ФГБОУ ВПО СПбГ АВМ) Инактивированная бивалентная гидроокись алюминиевая вакцина против кампилобактериоза собак
GB201703529D0 (en) 2017-03-06 2017-04-19 Cambridge Entpr Ltd Vaccine composition
CN110317749B (zh) * 2019-06-19 2021-01-22 山东省农业科学院奶牛研究中心 一株牛支原体强毒株及其应用
RU2764220C1 (ru) * 2020-12-02 2022-01-14 Федеральное государственное бюджетное научное учреждение "Краснодарский научный центр по зоотехнии и ветеринарии" ФГБНУ КНЦЗВ Способ предупреждения риска заболевания парагриппом-3 у телят

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3634587A (en) * 1969-11-06 1972-01-11 Ralston Purina Co Method of immunizing cattle against bovine respiratory disease syndrome
BE759425A (fr) * 1969-11-28 1971-05-25 Mebus Charles A Vaccins contre la diarrhee du veau, leur preparation et emploi
US5593873A (en) 1986-01-27 1997-01-14 Syntro Corporation Recombinant infectious bovine rhinotracheitis virus
US5084269A (en) 1986-11-06 1992-01-28 Kullenberg Fred W Adjuvant for dose treatment with antigens
DE3768232D1 (de) * 1986-12-19 1991-04-04 Duphar Int Res Dimethyldioctadecylammoniumbromid enthaltende stabilisierte adjuvanssuspension.
GB8818415D0 (en) * 1988-08-03 1988-09-07 Animal Health Inst Vaccine
US6291228B1 (en) * 1988-08-03 2001-09-18 Vericore Limited Vaccine
MX9301736A (es) 1992-03-30 1994-01-31 Smithkline Beecham Corp Vacuna de bacterina-toxoide de pasteurella haemolytica tipo a-1.
US5951988A (en) * 1993-03-30 1999-09-14 University Of Saskatchewan Adjuvant formulation with enhanced immunogenic activity, and related compositions and methods
EP0725831A1 (en) 1993-11-05 1996-08-14 PHARMACIA & UPJOHN COMPANY Viral vector with bovine viral diarrhea virus (bvdv) antigens
ZA953703B (en) * 1994-05-10 1996-01-10 American Home Prod Modified live BRSV vaccine
US5709865A (en) 1994-11-10 1998-01-20 Biostar Inc. Immunogenic composition against Bovine Viral Diarrhea Virus II glycoprotein 53 (BVDV-II gp53)
US6001613A (en) 1996-05-24 1999-12-14 Board Of Regents Of University Of Nebraska Plasmid bearing a cDNA copy of the genome of bovine viral diarrhea virus, chimeric derivatives thereof, and method of producing an infectious bovine viral diarrhea virus using said plasmid
US6060457A (en) 1996-06-20 2000-05-09 Universite De Montreal DNA plasmid vaccine for immunization of animals against BVDV
BR9803232A (pt) * 1997-08-26 2000-01-11 Pfizer Prod Inc Vaicna de neospora.
JP4426091B2 (ja) * 1997-09-05 2010-03-03 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム サポニンを含有する水中油型エマルション
UA78180C2 (uk) * 1997-10-03 2007-03-15 Меріаль Кільцевий вірус свині типу ii, вакцини та діагностичні реагенти
EP0924295A3 (en) * 1997-12-04 2001-05-16 Pfizer Products Inc. DNA encoding neospora dihydrofolate reductase-thymidylate synthase
CA2330086A1 (en) 1998-04-24 1999-11-04 Washington University Chimeras of hepatitis c virus and bovine viral diarrhea virus
AU769539B2 (en) * 1999-01-29 2004-01-29 Zoetis Services Llc Adjuvants for use in vaccines
CA2496750C (en) * 2002-08-26 2014-10-21 Pfizer Products Inc. Vaccine for respiratory and reproductive system infections in cattle
ES2365832T3 (es) 2007-03-05 2011-10-11 Cadila Healthcare Limited Composiciones que comprenden conjugados de peg-interferón alfa y rafinosa como crioprotector.

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US20130129779A1 (en) 2013-05-23
HRP20090271A2 (en) 2009-11-30
NO20050603L (no) 2005-03-17
KR20060116037A (ko) 2006-11-13
HK1078457A1 (en) 2006-03-17
UA94689C2 (ru) 2011-06-10
CN1315534C (zh) 2007-05-16
ZA200501171B (en) 2006-12-27
EP1536830A1 (en) 2005-06-08
AU2003263390A1 (en) 2004-03-11
AU2008258154A1 (en) 2009-01-08
JP2009215309A (ja) 2009-09-24
US20070298053A1 (en) 2007-12-27
BR0313806A (pt) 2005-07-05
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AU2003263390B2 (en) 2008-12-18
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HRP20050192B1 (hr) 2014-02-14
EA200500275A1 (ru) 2005-08-25
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