US533554A
(en)
|
|
1895-02-05 |
|
Henry d |
US533537A
(en)
|
|
1895-02-05 |
|
Watchmakers calipers |
US618953A
(en)
|
|
1899-02-07 |
|
Apparatus for preventing pounding or water-hammering in circulating-pipes of heating |
US576705A
(en)
|
|
1897-02-09 |
|
Vegetable cutter and grater |
US618862A
(en)
|
|
1899-02-07 |
|
Automatic stoker |
US618896A
(en)
|
|
1899-02-07 |
|
Potato-bug gatherer |
US618885A
(en)
|
|
1899-02-07 |
|
Railway-car brake |
US618873A
(en)
|
|
1899-02-07 |
|
Oyster-tongs |
US618957A
(en)
|
|
1899-02-07 |
|
Inda may kelly |
US681712A
(en)
|
1898-03-26 |
1901-09-03 |
American Railway Electric Light Co |
Means for controlling electric currents.
|
US648244A
(en)
|
1899-04-28 |
1900-04-24 |
Orrin A Dever |
Tank-mold.
|
US696381A
(en)
|
1900-03-01 |
1902-03-25 |
Hugo Loewenbach |
Paper-feeding machine.
|
US709303A
(en)
|
1901-11-19 |
1902-09-16 |
Edward Chester & Company Ltd |
Construction of tanks.
|
US712490A
(en)
|
1902-01-13 |
1902-11-04 |
Francis Blossom |
Economizer system.
|
US2008526A
(en)
|
1932-11-03 |
1935-07-16 |
Wappler Frederick Charles |
Method and means for treating living tissue
|
US2588623A
(en)
|
1948-05-10 |
1952-03-11 |
Eliscu Frank |
Surgical instrument for intradermal injection of fluids
|
US3467096A
(en)
|
1966-04-12 |
1969-09-16 |
Ferrell S Horn |
Multiple hypodermic syringe arrangement
|
US3572336A
(en)
|
1968-04-30 |
1971-03-23 |
Daniel R Hershberg |
Syringe
|
BE757653A
(fr)
|
1969-10-21 |
1971-04-16 |
Ugine Kuhlmann |
Nouveaux medicaments derives d'acides nucleiques et procedes pour leur preparation
|
BE786542A
(fr)
|
1971-07-22 |
1973-01-22 |
Dow Corning |
Dispositif d'aspiration permettant d'obtenir des echantillons de cellules
|
US3906092A
(en)
|
1971-11-26 |
1975-09-16 |
Merck & Co Inc |
Stimulation of antibody response
|
US4270537A
(en)
|
1979-11-19 |
1981-06-02 |
Romaine Richard A |
Automatic hypodermic syringe
|
US4399216A
(en)
|
1980-02-25 |
1983-08-16 |
The Trustees Of Columbia University |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
US5132418A
(en)
|
1980-02-29 |
1992-07-21 |
University Patents, Inc. |
Process for preparing polynucleotides
|
US4458066A
(en)
|
1980-02-29 |
1984-07-03 |
University Patents, Inc. |
Process for preparing polynucleotides
|
US4500707A
(en)
|
1980-02-29 |
1985-02-19 |
University Patents, Inc. |
Nucleosides useful in the preparation of polynucleotides
|
US4411657A
(en)
|
1980-05-19 |
1983-10-25 |
Anibal Galindo |
Hypodermic needle
|
US4415732A
(en)
|
1981-03-27 |
1983-11-15 |
University Patents, Inc. |
Phosphoramidite compounds and processes
|
US4973679A
(en)
|
1981-03-27 |
1990-11-27 |
University Patents, Inc. |
Process for oligonucleo tide synthesis using phosphormidite intermediates
|
US4668777A
(en)
|
1981-03-27 |
1987-05-26 |
University Patents, Inc. |
Phosphoramidite nucleoside compounds
|
US4401796A
(en)
|
1981-04-30 |
1983-08-30 |
City Of Hope Research Institute |
Solid-phase synthesis of polynucleotides
|
US4373071A
(en)
|
1981-04-30 |
1983-02-08 |
City Of Hope Research Institute |
Solid-phase synthesis of polynucleotides
|
US4474569A
(en)
|
1982-06-28 |
1984-10-02 |
Denver Surgical Developments, Inc. |
Antenatal shunt
|
JPS5927900A
(ja)
|
1982-08-09 |
1984-02-14 |
Wakunaga Seiyaku Kk |
固定化オリゴヌクレオチド
|
US4588585A
(en)
|
1982-10-19 |
1986-05-13 |
Cetus Corporation |
Human recombinant cysteine depleted interferon-β muteins
|
US4737462A
(en)
|
1982-10-19 |
1988-04-12 |
Cetus Corporation |
Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of interferon-β
|
FR2540122B1
(fr)
|
1983-01-27 |
1985-11-29 |
Centre Nat Rech Scient |
Nouveaux composes comportant une sequence d'oligonucleotide liee a un agent d'intercalation, leur procede de synthese et leur application
|
US4605735A
(en)
|
1983-02-14 |
1986-08-12 |
Wakunaga Seiyaku Kabushiki Kaisha |
Oligonucleotide derivatives
|
US4948882A
(en)
|
1983-02-22 |
1990-08-14 |
Syngene, Inc. |
Single-stranded labelled oligonucleotides, reactive monomers and methods of synthesis
|
US4824941A
(en)
|
1983-03-10 |
1989-04-25 |
Julian Gordon |
Specific antibody to the native form of 2'5'-oligonucleotides, the method of preparation and the use as reagents in immunoassays or for binding 2'5'-oligonucleotides in biological systems
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
US4587044A
(en)
|
1983-09-01 |
1986-05-06 |
The Johns Hopkins University |
Linkage of proteins to nucleic acids
|
US5118802A
(en)
|
1983-12-20 |
1992-06-02 |
California Institute Of Technology |
DNA-reporter conjugates linked via the 2' or 5'-primary amino group of the 5'-terminal nucleoside
|
US5118800A
(en)
|
1983-12-20 |
1992-06-02 |
California Institute Of Technology |
Oligonucleotides possessing a primary amino group in the terminal nucleotide
|
US4579849A
(en)
|
1984-04-06 |
1986-04-01 |
Merck & Co., Inc. |
N-alkylguanine acyclonucleosides as antiviral agents
|
US4957735A
(en)
|
1984-06-12 |
1990-09-18 |
The University Of Tennessee Research Corporation |
Target-sensitive immunoliposomes- preparation and characterization
|
FR2567892B1
(fr)
|
1984-07-19 |
1989-02-17 |
Centre Nat Rech Scient |
Nouveaux oligonucleotides, leur procede de preparation et leurs applications comme mediateurs dans le developpement des effets des interferons
|
US5430136A
(en)
|
1984-10-16 |
1995-07-04 |
Chiron Corporation |
Oligonucleotides having selectably cleavable and/or abasic sites
|
US5258506A
(en)
|
1984-10-16 |
1993-11-02 |
Chiron Corporation |
Photolabile reagents for incorporation into oligonucleotide chains
|
US4828979A
(en)
|
1984-11-08 |
1989-05-09 |
Life Technologies, Inc. |
Nucleotide analogs for nucleic acid labeling and detection
|
US4959314A
(en)
|
1984-11-09 |
1990-09-25 |
Cetus Corporation |
Cysteine-depleted muteins of biologically active proteins
|
US5036006A
(en)
|
1984-11-13 |
1991-07-30 |
Cornell Research Foundation, Inc. |
Method for transporting substances into living cells and tissues and apparatus therefor
|
US5116943A
(en)
|
1985-01-18 |
1992-05-26 |
Cetus Corporation |
Oxidation-resistant muteins of Il-2 and other protein
|
CA1288073C
(en)
|
1985-03-07 |
1991-08-27 |
Paul G. Ahlquist |
Rna transformation vector
|
US5034506A
(en)
|
1985-03-15 |
1991-07-23 |
Anti-Gene Development Group |
Uncharged morpholino-based polymers having achiral intersubunit linkages
|
US4596556A
(en)
|
1985-03-25 |
1986-06-24 |
Bioject, Inc. |
Hypodermic injection apparatus
|
EP0204401A1
(en)
|
1985-04-09 |
1986-12-10 |
Biogen, Inc. |
Method of improving the yield of polypeptides produced in a host cell by stabilizing mRNA
|
US4762779A
(en)
|
1985-06-13 |
1988-08-09 |
Amgen Inc. |
Compositions and methods for functionalizing nucleic acids
|
US5017691A
(en)
|
1986-07-03 |
1991-05-21 |
Schering Corporation |
Mammalian interleukin-4
|
US5317098A
(en)
|
1986-03-17 |
1994-05-31 |
Hiroaki Shizuya |
Non-radioisotope tagging of fragments
|
US5153319A
(en)
|
1986-03-31 |
1992-10-06 |
University Patents, Inc. |
Process for preparing polynucleotides
|
US4695273A
(en)
|
1986-04-08 |
1987-09-22 |
I-Flow Corporation |
Multiple needle holder and subcutaneous multiple channel infusion port
|
US4879111A
(en)
|
1986-04-17 |
1989-11-07 |
Cetus Corporation |
Treatment of infections with lymphokines
|
JPS638396A
(ja)
|
1986-06-30 |
1988-01-14 |
Wakunaga Pharmaceut Co Ltd |
ポリ標識化オリゴヌクレオチド誘導体
|
US4886499A
(en)
|
1986-12-18 |
1989-12-12 |
Hoffmann-La Roche Inc. |
Portable injection appliance
|
GB8704027D0
(en)
|
1987-02-20 |
1987-03-25 |
Owen Mumford Ltd |
Syringe needle combination
|
US4904582A
(en)
|
1987-06-11 |
1990-02-27 |
Synthetic Genetics |
Novel amphiphilic nucleic acid conjugates
|
US4941880A
(en)
|
1987-06-19 |
1990-07-17 |
Bioject, Inc. |
Pre-filled ampule and non-invasive hypodermic injection device assembly
|
US4940460A
(en)
|
1987-06-19 |
1990-07-10 |
Bioject, Inc. |
Patient-fillable and non-invasive hypodermic injection device assembly
|
US4790824A
(en)
|
1987-06-19 |
1988-12-13 |
Bioject, Inc. |
Non-invasive hypodermic injection device
|
US6090591A
(en)
|
1987-07-31 |
2000-07-18 |
The Board Of Trustees Of The Leland Stanford Junior University |
Selective amplification of target polynucleotide sequences
|
JP2774121B2
(ja)
|
1987-07-31 |
1998-07-09 |
ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニバーシティ |
標的ポリヌクレオチド配列の選択的増幅
|
US5585481A
(en)
|
1987-09-21 |
1996-12-17 |
Gen-Probe Incorporated |
Linking reagents for nucleotide probes
|
US5525465A
(en)
|
1987-10-28 |
1996-06-11 |
Howard Florey Institute Of Experimental Physiology And Medicine |
Oligonucleotide-polyamide conjugates and methods of production and applications of the same
|
DE3738460A1
(de)
|
1987-11-12 |
1989-05-24 |
Max Planck Gesellschaft |
Modifizierte oligonukleotide
|
DE68908054T2
(de)
|
1988-01-21 |
1994-03-10 |
Genentech Inc |
Verstärkung und nachweis von nukleinsäuresequenzen.
|
JP2650159B2
(ja)
|
1988-02-24 |
1997-09-03 |
アクゾ・ノベル・エヌ・ベー |
核酸増幅方法
|
CA1340807C
(en)
|
1988-02-24 |
1999-11-02 |
Lawrence T. Malek |
Nucleic acid amplification process
|
US5082830A
(en)
|
1988-02-26 |
1992-01-21 |
Enzo Biochem, Inc. |
End labeled nucleotide probe
|
WO1989007947A1
(en)
|
1988-03-04 |
1989-09-08 |
Cancer Research Campaign Technology Limited |
Improvements relating to antigens
|
US5339163A
(en)
|
1988-03-16 |
1994-08-16 |
Canon Kabushiki Kaisha |
Automatic exposure control device using plural image plane detection areas
|
WO1989009622A1
(en)
|
1988-04-15 |
1989-10-19 |
Protein Design Labs, Inc. |
Il-2 receptor-specific chimeric antibodies
|
US5109124A
(en)
|
1988-06-01 |
1992-04-28 |
Biogen, Inc. |
Nucleic acid probe linked to a label having a terminal cysteine
|
US5168038A
(en)
|
1988-06-17 |
1992-12-01 |
The Board Of Trustees Of The Leland Stanford Junior University |
In situ transcription in cells and tissues
|
US5021335A
(en)
|
1988-06-17 |
1991-06-04 |
The Board Of Trustees Of The Leland Stanford Junior University |
In situ transcription in cells and tissues
|
US5130238A
(en)
|
1988-06-24 |
1992-07-14 |
Cangene Corporation |
Enhanced nucleic acid amplification process
|
US5262536A
(en)
|
1988-09-15 |
1993-11-16 |
E. I. Du Pont De Nemours And Company |
Reagents for the preparation of 5'-tagged oligonucleotides
|
US5759802A
(en)
|
1988-10-26 |
1998-06-02 |
Tonen Corporation |
Production of human serum alubumin A
|
FR2638359A1
(fr)
|
1988-11-03 |
1990-05-04 |
Tino Dalto |
Guide de seringue avec reglage de la profondeur de penetration de l'aiguille dans la peau
|
US5512439A
(en)
|
1988-11-21 |
1996-04-30 |
Dynal As |
Oligonucleotide-linked magnetic particles and uses thereof
|
US5262530A
(en)
|
1988-12-21 |
1993-11-16 |
Applied Biosystems, Inc. |
Automated system for polynucleotide synthesis and purification
|
US5047524A
(en)
|
1988-12-21 |
1991-09-10 |
Applied Biosystems, Inc. |
Automated system for polynucleotide synthesis and purification
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
US5457183A
(en)
|
1989-03-06 |
1995-10-10 |
Board Of Regents, The University Of Texas System |
Hydroxylated texaphyrins
|
US5599923A
(en)
|
1989-03-06 |
1997-02-04 |
Board Of Regents, University Of Tx |
Texaphyrin metal complexes having improved functionalization
|
US6214804B1
(en)
|
1989-03-21 |
2001-04-10 |
Vical Incorporated |
Induction of a protective immune response in a mammal by injecting a DNA sequence
|
AU5344190A
(en)
|
1989-03-21 |
1990-10-22 |
Vical, Inc. |
Expression of exogenous polynucleotide sequences in a vertebrate
|
US6673776B1
(en)
|
1989-03-21 |
2004-01-06 |
Vical Incorporated |
Expression of exogenous polynucleotide sequences in a vertebrate, mammal, fish, bird or human
|
US6867195B1
(en)
|
1989-03-21 |
2005-03-15 |
Vical Incorporated |
Lipid-mediated polynucleotide administration to reduce likelihood of subject's becoming infected
|
US5693622A
(en)
|
1989-03-21 |
1997-12-02 |
Vical Incorporated |
Expression of exogenous polynucleotide sequences cardiac muscle of a mammal
|
US5703055A
(en)
|
1989-03-21 |
1997-12-30 |
Wisconsin Alumni Research Foundation |
Generation of antibodies through lipid mediated DNA delivery
|
US5012818A
(en)
|
1989-05-04 |
1991-05-07 |
Joishy Suresh K |
Two in one bone marrow surgical needle
|
IE66597B1
(en)
|
1989-05-10 |
1996-01-24 |
Akzo Nv |
Method for the synthesis of ribonucleic acid (RNA)
|
US5332671A
(en)
|
1989-05-12 |
1994-07-26 |
Genetech, Inc. |
Production of vascular endothelial cell growth factor and DNA encoding same
|
US5240855A
(en)
|
1989-05-12 |
1993-08-31 |
Pioneer Hi-Bred International, Inc. |
Particle gun
|
US5391723A
(en)
|
1989-05-31 |
1995-02-21 |
Neorx Corporation |
Oligonucleotide conjugates
|
US4958013A
(en)
|
1989-06-06 |
1990-09-18 |
Northwestern University |
Cholesteryl modified oligonucleotides
|
CA2020958C
(en)
|
1989-07-11 |
2005-01-11 |
Daniel L. Kacian |
Nucleic acid sequence amplification methods
|
US5451463A
(en)
|
1989-08-28 |
1995-09-19 |
Clontech Laboratories, Inc. |
Non-nucleoside 1,3-diol reagents for labeling synthetic oligonucleotides
|
US5254469A
(en)
|
1989-09-12 |
1993-10-19 |
Eastman Kodak Company |
Oligonucleotide-enzyme conjugate that can be used as a probe in hybridization assays and polymerase chain reaction procedures
|
US5591722A
(en)
|
1989-09-15 |
1997-01-07 |
Southern Research Institute |
2'-deoxy-4'-thioribonucleosides and their antiviral activity
|
US5545522A
(en)
|
1989-09-22 |
1996-08-13 |
Van Gelder; Russell N. |
Process for amplifying a target polynucleotide sequence using a single primer-promoter complex
|
AU658562B2
(en)
|
1989-10-24 |
1995-04-27 |
Isis Pharmaceuticals, Inc. |
2' modified oligonucleotides
|
US5208020A
(en)
|
1989-10-25 |
1993-05-04 |
Immunogen Inc. |
Cytotoxic agents comprising maytansinoids and their therapeutic use
|
US5215899A
(en)
|
1989-11-09 |
1993-06-01 |
Miles Inc. |
Nucleic acid amplification employing ligatable hairpin probe and transcription
|
US5064413A
(en)
|
1989-11-09 |
1991-11-12 |
Bioject, Inc. |
Needleless hypodermic injection device
|
US5312335A
(en)
|
1989-11-09 |
1994-05-17 |
Bioject Inc. |
Needleless hypodermic injection device
|
NO904633L
(no)
|
1989-11-09 |
1991-05-10 |
Molecular Diagnostics Inc |
Amplifikasjon av nukleinsyrer ved transkriberbar haarnaalsprobe.
|
US5292873A
(en)
|
1989-11-29 |
1994-03-08 |
The Research Foundation Of State University Of New York |
Nucleic acids labeled with naphthoquinone probe
|
US5633076A
(en)
|
1989-12-01 |
1997-05-27 |
Pharming Bv |
Method of producing a transgenic bovine or transgenic bovine embryo
|
US5697901A
(en)
|
1989-12-14 |
1997-12-16 |
Elof Eriksson |
Gene delivery by microneedle injection
|
US5486603A
(en)
|
1990-01-08 |
1996-01-23 |
Gilead Sciences, Inc. |
Oligonucleotide having enhanced binding affinity
|
US5578718A
(en)
|
1990-01-11 |
1996-11-26 |
Isis Pharmaceuticals, Inc. |
Thiol-derivatized nucleosides
|
US6783931B1
(en)
|
1990-01-11 |
2004-08-31 |
Isis Pharmaceuticals, Inc. |
Amine-derivatized nucleosides and oligonucleosides
|
US7037646B1
(en)
|
1990-01-11 |
2006-05-02 |
Isis Pharmaceuticals, Inc. |
Amine-derivatized nucleosides and oligonucleosides
|
US5646265A
(en)
|
1990-01-11 |
1997-07-08 |
Isis Pharmceuticals, Inc. |
Process for the preparation of 2'-O-alkyl purine phosphoramidites
|
US5670633A
(en)
|
1990-01-11 |
1997-09-23 |
Isis Pharmaceuticals, Inc. |
Sugar modified oligonucleotides that detect and modulate gene expression
|
AU7579991A
(en)
|
1990-02-20 |
1991-09-18 |
Gilead Sciences, Inc. |
Pseudonucleosides and pseudonucleotides and their polymers
|
US5214136A
(en)
|
1990-02-20 |
1993-05-25 |
Gilead Sciences, Inc. |
Anthraquinone-derivatives oligonucleotides
|
US5264618A
(en)
*
|
1990-04-19 |
1993-11-23 |
Vical, Inc. |
Cationic lipids for intracellular delivery of biologically active molecules
|
GB9009980D0
(en)
|
1990-05-03 |
1990-06-27 |
Amersham Int Plc |
Phosphoramidite derivatives,their preparation and the use thereof in the incorporation of reporter groups on synthetic oligonucleotides
|
ATE167523T1
(de)
|
1990-05-11 |
1998-07-15 |
Microprobe Corp |
Teststreifen zum eintauchen für nukleinsäure- hybridisierungsassays und verfahren zur kovalenten immobilisierung von oligonucleotiden
|
US5194370A
(en)
|
1990-05-16 |
1993-03-16 |
Life Technologies, Inc. |
Promoter ligation activated transcription amplification of nucleic acid sequences
|
AU649066B2
(en)
|
1990-07-25 |
1994-05-12 |
Syngene, Inc. |
Circular extension for generating multiple nucleic acid complements
|
US5489677A
(en)
|
1990-07-27 |
1996-02-06 |
Isis Pharmaceuticals, Inc. |
Oligonucleoside linkages containing adjacent oxygen and nitrogen atoms
|
US5688941A
(en)
|
1990-07-27 |
1997-11-18 |
Isis Pharmaceuticals, Inc. |
Methods of making conjugated 4' desmethyl nucleoside analog compounds
|
US5218105A
(en)
|
1990-07-27 |
1993-06-08 |
Isis Pharmaceuticals |
Polyamine conjugated oligonucleotides
|
US5138045A
(en)
|
1990-07-27 |
1992-08-11 |
Isis Pharmaceuticals |
Polyamine conjugated oligonucleotides
|
US5608046A
(en)
|
1990-07-27 |
1997-03-04 |
Isis Pharmaceuticals, Inc. |
Conjugated 4'-desmethyl nucleoside analog compounds
|
US5602240A
(en)
|
1990-07-27 |
1997-02-11 |
Ciba Geigy Ag. |
Backbone modified oligonucleotide analogs
|
US5245022A
(en)
|
1990-08-03 |
1993-09-14 |
Sterling Drug, Inc. |
Exonuclease resistant terminally substituted oligonucleotides
|
US5190521A
(en)
|
1990-08-22 |
1993-03-02 |
Tecnol Medical Products, Inc. |
Apparatus and method for raising a skin wheal and anesthetizing skin
|
US5512667A
(en)
|
1990-08-28 |
1996-04-30 |
Reed; Michael W. |
Trifunctional intermediates for preparing 3'-tailed oligonucleotides
|
US6140496A
(en)
|
1990-10-09 |
2000-10-31 |
Benner; Steven Albert |
Precursors for deoxyribonucleotides containing non-standard nucleosides
|
DE69132510T2
(de)
|
1990-11-08 |
2001-05-03 |
Hybridon Inc |
Verbindung von mehrfachreportergruppen auf synthetischen oligonukleotiden
|
US5527288A
(en)
|
1990-12-13 |
1996-06-18 |
Elan Medical Technologies Limited |
Intradermal drug delivery device and method for intradermal delivery of drugs
|
US6100024A
(en)
|
1991-02-08 |
2000-08-08 |
Promega Corporation |
Methods and compositions for nucleic acid detection by target extension and probe amplification
|
DE69231828T3
(de)
|
1991-03-18 |
2008-06-19 |
New York University |
Spezifisch gegen menschlichen Tumornekrosefaktor gerichtete monoklonale und chimäre Antikörper
|
US5426180A
(en)
|
1991-03-27 |
1995-06-20 |
Research Corporation Technologies, Inc. |
Methods of making single-stranded circular oligonucleotides
|
JP3370324B2
(ja)
|
1991-04-25 |
2003-01-27 |
中外製薬株式会社 |
ヒトインターロイキン−6受容体に対する再構成ヒト抗体
|
US5714331A
(en)
|
1991-05-24 |
1998-02-03 |
Buchardt, Deceased; Ole |
Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility
|
US5539082A
(en)
|
1993-04-26 |
1996-07-23 |
Nielsen; Peter E. |
Peptide nucleic acids
|
US5719262A
(en)
|
1993-11-22 |
1998-02-17 |
Buchardt, Deceased; Ole |
Peptide nucleic acids having amino acid side chains
|
US5169766A
(en)
|
1991-06-14 |
1992-12-08 |
Life Technologies, Inc. |
Amplification of nucleic acid molecules
|
US5371241A
(en)
|
1991-07-19 |
1994-12-06 |
Pharmacia P-L Biochemicals Inc. |
Fluorescein labelled phosphoramidites
|
US5199441A
(en)
|
1991-08-20 |
1993-04-06 |
Hogle Hugh H |
Fine needle aspiration biopsy apparatus and method
|
GB9118204D0
(en)
|
1991-08-23 |
1991-10-09 |
Weston Terence E |
Needle-less injector
|
SE9102652D0
(sv)
|
1991-09-13 |
1991-09-13 |
Kabi Pharmacia Ab |
Injection needle arrangement
|
EP0538194B1
(de)
|
1991-10-17 |
1997-06-04 |
Novartis AG |
Bicyclische Nukleoside, Oligonukleotide, Verfahren zu deren Herstellung und Zwischenprodukte
|
US5298422A
(en)
|
1991-11-06 |
1994-03-29 |
Baylor College Of Medicine |
Myogenic vector systems
|
US5359044A
(en)
|
1991-12-13 |
1994-10-25 |
Isis Pharmaceuticals |
Cyclobutyl oligonucleotide surrogates
|
US5824307A
(en)
|
1991-12-23 |
1998-10-20 |
Medimmune, Inc. |
Human-murine chimeric antibodies against respiratory syncytial virus
|
US5595726A
(en)
|
1992-01-21 |
1997-01-21 |
Pharmacyclics, Inc. |
Chromophore probe for detection of nucleic acid
|
US5565552A
(en)
|
1992-01-21 |
1996-10-15 |
Pharmacyclics, Inc. |
Method of expanded porphyrin-oligonucleotide conjugate synthesis
|
WO1993014778A1
(en)
|
1992-01-23 |
1993-08-05 |
Vical, Inc. |
Ex vivo gene transfer
|
FR2687679B1
(fr)
|
1992-02-05 |
1994-10-28 |
Centre Nat Rech Scient |
Oligothionucleotides.
|
US5328483A
(en)
|
1992-02-27 |
1994-07-12 |
Jacoby Richard M |
Intradermal injection device with medication and needle guard
|
JP3368603B2
(ja)
|
1992-02-28 |
2003-01-20 |
オリンパス光学工業株式会社 |
遺伝子治療用処置具
|
ES2149768T3
(es)
|
1992-03-25 |
2000-11-16 |
Immunogen Inc |
Conjugados de agentes enlazantes de celulas derivados de cc-1065.
|
US6174666B1
(en)
|
1992-03-27 |
2001-01-16 |
The United States Of America As Represented By The Department Of Health And Human Services |
Method of eliminating inhibitory/instability regions from mRNA
|
US6132419A
(en)
|
1992-05-22 |
2000-10-17 |
Genetronics, Inc. |
Electroporetic gene and drug therapy
|
US5514545A
(en)
|
1992-06-11 |
1996-05-07 |
Trustees Of The University Of Pennsylvania |
Method for characterizing single cells based on RNA amplification for diagnostics and therapeutics
|
EP0577558A2
(de)
|
1992-07-01 |
1994-01-05 |
Ciba-Geigy Ag |
Carbocyclische Nukleoside mit bicyclischen Ringen, Oligonukleotide daraus, Verfahren zu deren Herstellung, deren Verwendung und Zwischenproduckte
|
US5272250A
(en)
|
1992-07-10 |
1993-12-21 |
Spielvogel Bernard F |
Boronated phosphoramidate compounds
|
US6670178B1
(en)
|
1992-07-10 |
2003-12-30 |
Transkaryotic Therapies, Inc. |
In Vivo production and delivery of insulinotropin for gene therapy
|
US5383851A
(en)
|
1992-07-24 |
1995-01-24 |
Bioject Inc. |
Needleless hypodermic injection device
|
WO1994003637A1
(en)
|
1992-07-31 |
1994-02-17 |
Syntex (Usa) Inc. |
Method for introducing defined sequences at the 3' end of polynucleotides
|
US5273525A
(en)
|
1992-08-13 |
1993-12-28 |
Btx Inc. |
Injection and electroporation apparatus for drug and gene delivery
|
US5240885A
(en)
|
1992-09-21 |
1993-08-31 |
Corning Incorporated |
Rare earth-doped, stabilized cadmium halide glasses
|
US5569189A
(en)
|
1992-09-28 |
1996-10-29 |
Equidyne Systems, Inc. |
hypodermic jet injector
|
US5334144A
(en)
|
1992-10-30 |
1994-08-02 |
Becton, Dickinson And Company |
Single use disposable needleless injector
|
AU5665694A
(en)
|
1992-11-04 |
1994-05-24 |
Denver Biomaterials Inc. |
Apparatus for removal of pleural effusion fluid
|
US5736137A
(en)
|
1992-11-13 |
1998-04-07 |
Idec Pharmaceuticals Corporation |
Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma
|
JP3095175B2
(ja)
|
1992-11-13 |
2000-10-03 |
アイデック ファーマシューティカルズ コーポレイション |
B細胞リンパ腫の治療のためのヒトbリンパ球限定分化抗原に対するキメラ抗体と放射能標識抗体の療法利用
|
US5574142A
(en)
|
1992-12-15 |
1996-11-12 |
Microprobe Corporation |
Peptide linkers for improved oligonucleotide delivery
|
DE69419721T2
(de)
|
1993-01-12 |
2000-04-27 |
Biogen Inc |
Rekombinante anti-vla4 antikörpermoleküle
|
FR2703253B1
(fr)
|
1993-03-30 |
1995-06-23 |
Centre Nat Rech Scient |
Applicateur d'impulsions electriques pour traitement de tissus biologiques.
|
JPH08508492A
(ja)
|
1993-03-30 |
1996-09-10 |
スターリング ウィンスロップ インコーポレイティド |
非環式ヌクレオシド類似体及びそれらを含むオリゴヌクレオチド配列
|
DE4311944A1
(de)
|
1993-04-10 |
1994-10-13 |
Degussa |
Umhüllte Natriumpercarbonatpartikel, Verfahren zu deren Herstellung und sie enthaltende Wasch-, Reinigungs- und Bleichmittelzusammensetzungen
|
US7135312B2
(en)
|
1993-04-15 |
2006-11-14 |
University Of Rochester |
Circular DNA vectors for synthesis of RNA and DNA
|
US5773244A
(en)
|
1993-05-19 |
1998-06-30 |
Regents Of The University Of California |
Methods of making circular RNA
|
US5851829A
(en)
|
1993-07-16 |
1998-12-22 |
Dana-Farber Cancer Institute |
Method of intracellular binding of target molecules
|
US6294664B1
(en)
|
1993-07-29 |
2001-09-25 |
Isis Pharmaceuticals, Inc. |
Synthesis of oligonucleotides
|
US5672491A
(en)
|
1993-09-20 |
1997-09-30 |
The Leland Stanford Junior University |
Recombinant production of novel polyketides
|
US6432711B1
(en)
|
1993-11-03 |
2002-08-13 |
Diacrin, Inc. |
Embryonic stem cells capable of differentiating into desired cell lines
|
US6096503A
(en)
|
1993-11-12 |
2000-08-01 |
The Scripps Research Institute |
Method for simultaneous identification of differentially expresses mRNAs and measurement of relative concentrations
|
US5446137B1
(en)
|
1993-12-09 |
1998-10-06 |
Behringwerke Ag |
Oligonucleotides containing 4'-substituted nucleotides
|
US5519134A
(en)
|
1994-01-11 |
1996-05-21 |
Isis Pharmaceuticals, Inc. |
Pyrrolidine-containing monomers and oligomers
|
US7435802B2
(en)
|
1994-01-25 |
2008-10-14 |
Elan Pharaceuticals, Inc. |
Humanized anti-VLA4 immunoglobulins
|
US5840299A
(en)
|
1994-01-25 |
1998-11-24 |
Athena Neurosciences, Inc. |
Humanized antibodies against leukocyte adhesion molecule VLA-4
|
DE69533295T3
(de)
|
1994-02-16 |
2009-07-16 |
The Government Of The United States Of America, As Represented By The Secretary, The Department Of Health And Human Services |
Melanoma-assoziierte Antigene, Epitope davon und Impstoffe gegen Melanoma
|
ATE241340T1
(de)
*
|
1994-02-17 |
2003-06-15 |
New York Blood Ct Inc |
Biologische bioadhäsive präparate, die fibrinkleber und liposomen enthalten, verfahren für ihre herstellung und verwendung
|
IL112820A0
(en)
|
1994-03-07 |
1995-05-26 |
Merck & Co Inc |
Coordinate in vivo gene expression
|
WO1995024176A1
(en)
|
1994-03-07 |
1995-09-14 |
Bioject, Inc. |
Ampule filling device
|
US5466220A
(en)
|
1994-03-08 |
1995-11-14 |
Bioject, Inc. |
Drug vial mixing and transfer device
|
WO1995025814A1
(en)
|
1994-03-18 |
1995-09-28 |
Lynx Therapeutics, Inc. |
Oligonucleotide n3'→p5' phosphoramidates: synthesis and compounds; hybridization and nuclease resistance properties
|
US5457041A
(en)
|
1994-03-25 |
1995-10-10 |
Science Applications International Corporation |
Needle array and method of introducing biological substances into living cells using the needle array
|
WO1995026204A1
(en)
|
1994-03-25 |
1995-10-05 |
Isis Pharmaceuticals, Inc. |
Immune stimulation by phosphorothioate oligonucleotide analogs
|
US5627053A
(en)
|
1994-03-29 |
1997-05-06 |
Ribozyme Pharmaceuticals, Inc. |
2'deoxy-2'-alkylnucleotide containing nucleic acid
|
US5464395A
(en)
|
1994-04-05 |
1995-11-07 |
Faxon; David P. |
Catheter for delivering therapeutic and/or diagnostic agents to the tissue surrounding a bodily passageway
|
US6074642A
(en)
|
1994-05-02 |
2000-06-13 |
Alexion Pharmaceuticals, Inc. |
Use of antibodies specific to human complement component C5 for the treatment of glomerulonephritis
|
IL113776A
(en)
|
1994-05-18 |
2008-12-29 |
Bayer Bioscience Gmbh |
Dna sequences coding for enzymes which catalyze the synthesis of linear alpha 1,4 - glucans in plants, fungi and microorganisms
|
AU2656295A
(en)
|
1994-06-02 |
1996-01-04 |
Chiron Corporation |
Nucleic acid immunization using a virus-based infection/transfection system
|
GB9412230D0
(en)
|
1994-06-17 |
1994-08-10 |
Celltech Ltd |
Interleukin-5 specific recombiant antibodies
|
US6239116B1
(en)
|
1994-07-15 |
2001-05-29 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
US5597696A
(en)
|
1994-07-18 |
1997-01-28 |
Becton Dickinson And Company |
Covalent cyanine dye oligonucleotide conjugates
|
WO1996004925A1
(en)
|
1994-08-12 |
1996-02-22 |
Immunomedics, Inc. |
Immunoconjugates and humanized antibodies specific for b-cell lymphoma and leukemia cells
|
US5597909A
(en)
|
1994-08-25 |
1997-01-28 |
Chiron Corporation |
Polynucleotide reagents containing modified deoxyribose moieties, and associated methods of synthesis and use
|
US5580731A
(en)
|
1994-08-25 |
1996-12-03 |
Chiron Corporation |
N-4 modified pyrimidine deoxynucleotides and oligonucleotide probes synthesized therewith
|
US5665545A
(en)
|
1994-11-28 |
1997-09-09 |
Akzo Nobel N.V. |
Terminal repeat amplification method
|
US5641665A
(en)
|
1994-11-28 |
1997-06-24 |
Vical Incorporated |
Plasmids suitable for IL-2 expression
|
US5588960A
(en)
|
1994-12-01 |
1996-12-31 |
Vidamed, Inc. |
Transurethral needle delivery device with cystoscope and method for treatment of urinary incontinence
|
US5807718A
(en)
|
1994-12-02 |
1998-09-15 |
The Scripps Research Institute |
Enzymatic DNA molecules
|
US5585108A
(en)
|
1994-12-30 |
1996-12-17 |
Nanosystems L.L.C. |
Formulations of oral gastrointestinal therapeutic agents in combination with pharmaceutically acceptable clays
|
PT795018E
(pt)
|
1995-01-06 |
2007-12-21 |
Plant Res Int Bv |
Sequências de adn codificando enzimas de síntese de polímeros de hidratos de carbono e método para a produção de plantas transgénicas
|
US5599302A
(en)
|
1995-01-09 |
1997-02-04 |
Medi-Ject Corporation |
Medical injection system and method, gas spring thereof and launching device using gas spring
|
US5795587A
(en)
|
1995-01-23 |
1998-08-18 |
University Of Pittsburgh |
Stable lipid-comprising drug delivery complexes and methods for their production
|
US5824497A
(en)
|
1995-02-10 |
1998-10-20 |
Mcmaster University |
High efficiency translation of mRNA molecules
|
DE69629326D1
(de)
|
1995-02-15 |
2003-09-11 |
Joseph Eldor |
Spinalnadel mit mehreren Löchern
|
DE69621507T2
(de)
|
1995-03-28 |
2003-01-09 |
Japan Science & Tech Corp |
Verfahren zur molekularen Indexierung von Genen unter Verwendung von Restriktionsenzymen
|
US5869230A
(en)
|
1995-03-30 |
1999-02-09 |
Beth Israel Hospital Association |
Gene transfer into the kidney
|
US5986054A
(en)
|
1995-04-28 |
1999-11-16 |
The Hospital For Sick Children, Hsc Research And Development Limited Partnership |
Genetic sequences and proteins related to alzheimer's disease
|
FR2733762B1
(fr)
|
1995-05-02 |
1997-08-01 |
Genset Sa |
Methode de couplage specifique de la coiffe de l'extremite 5' d'un fragment d'arnm et preparation d'arnm et d'adnc complet
|
US5700642A
(en)
|
1995-05-22 |
1997-12-23 |
Sri International |
Oligonucleotide sizing using immobilized cleavable primers
|
US5730723A
(en)
|
1995-10-10 |
1998-03-24 |
Visionary Medical Products Corporation, Inc. |
Gas pressured needle-less injection device and method
|
US6051429A
(en)
|
1995-06-07 |
2000-04-18 |
Life Technologies, Inc. |
Peptide-enhanced cationic lipid transfections
|
US6111095A
(en)
|
1995-06-07 |
2000-08-29 |
Merck & Co., Inc. |
Capped synthetic RNA, analogs, and aptamers
|
US5889136A
(en)
|
1995-06-09 |
1999-03-30 |
The Regents Of The University Of Colorado |
Orthoester protecting groups in RNA synthesis
|
US5713863A
(en)
|
1996-01-11 |
1998-02-03 |
Interventional Technologies Inc. |
Catheter with fluid medication injectors
|
US5766903A
(en)
|
1995-08-23 |
1998-06-16 |
University Technology Corporation |
Circular RNA and uses thereof
|
US6265389B1
(en)
|
1995-08-31 |
2001-07-24 |
Alkermes Controlled Therapeutics, Inc. |
Microencapsulation and sustained release of oligonucleotides
|
AU7073096A
(en)
|
1995-09-19 |
1997-04-09 |
University Of Massachusetts |
Inhibited biological degradation of oligodeoxynucleotides
|
US5830879A
(en)
|
1995-10-02 |
1998-11-03 |
St. Elizabeth's Medical Center Of Boston, Inc. |
Treatment of vascular injury using vascular endothelial growth factor
|
US6265387B1
(en)
|
1995-10-11 |
2001-07-24 |
Mirus, Inc. |
Process of delivering naked DNA into a hepatocyte via bile duct
|
EP0771873A3
(en)
|
1995-10-27 |
1998-03-04 |
Takeda Chemical Industries, Ltd. |
Neuronal cell-specific receptor protein
|
CU22584A1
(es)
|
1995-11-17 |
1999-11-03 |
Centro Inmunologia Molecular |
Composiciones farmacéuticas que contienen un anticuerpo monoclonal que reconoce el antígeno de diferenciación leucocitario humano cd6 y sus usos para el diagnóstico y tratamiento de la psoriasis
|
US6090382A
(en)
|
1996-02-09 |
2000-07-18 |
Basf Aktiengesellschaft |
Human antibodies that bind human TNFα
|
US5962271A
(en)
|
1996-01-03 |
1999-10-05 |
Cloutech Laboratories, Inc. |
Methods and compositions for generating full-length cDNA having arbitrary nucleotide sequence at the 3'-end
|
US5893397A
(en)
|
1996-01-12 |
1999-04-13 |
Bioject Inc. |
Medication vial/syringe liquid-transfer apparatus
|
US6261584B1
(en)
|
1996-02-02 |
2001-07-17 |
Alza Corporation |
Sustained delivery of an active agent using an implantable system
|
US6395292B2
(en)
|
1996-02-02 |
2002-05-28 |
Alza Corporation |
Sustained delivery of an active agent using an implantable system
|
AU1874397A
(en)
|
1996-02-16 |
1997-09-02 |
Stichting Rega Vzw |
Hexitol containing oligonucleotides and their use in antisense strategies
|
US6534312B1
(en)
|
1996-02-22 |
2003-03-18 |
Merck & Co., Inc. |
Vaccines comprising synthetic genes
|
US6090391A
(en)
|
1996-02-23 |
2000-07-18 |
Aviron |
Recombinant tryptophan mutants of influenza
|
US6300487B1
(en)
|
1996-03-19 |
2001-10-09 |
Cell Therapuetics, Inc. |
Mammalian lysophosphatidic acid acyltransferase
|
SE9601245D0
(sv)
|
1996-03-29 |
1996-03-29 |
Pharmacia Ab |
Chimeric superantigens and their use
|
TW517061B
(en)
|
1996-03-29 |
2003-01-11 |
Pharmacia & Amp Upjohn Ab |
Modified/chimeric superantigens and their use
|
GB9607549D0
(en)
|
1996-04-11 |
1996-06-12 |
Weston Medical Ltd |
Spring-powered dispensing device
|
US20030073908A1
(en)
|
1996-04-26 |
2003-04-17 |
2000 Injectx, Inc. |
Method and apparatus for delivery of genes, enzymes and biological agents to tissue cells
|
US5712127A
(en)
|
1996-04-29 |
1998-01-27 |
Genescape Inc. |
Subtractive amplification
|
US5853719A
(en)
|
1996-04-30 |
1998-12-29 |
Duke University |
Methods for treating cancers and pathogen infections using antigen-presenting cells loaded with RNA
|
US7329741B2
(en)
|
1996-06-05 |
2008-02-12 |
Chiron Corporation |
Polynucleotides that hybridize to DP-75 and their use
|
ATE438717T1
(de)
|
1996-06-05 |
2009-08-15 |
Novartis Vaccines & Diagnostic |
Dp-75 kodierende dna und verfahren zu ihrer verwendung
|
WO1997048370A2
(en)
|
1996-06-21 |
1997-12-24 |
Merck & Co., Inc. |
Vaccines comprising synthetic genes
|
US6234990B1
(en)
|
1996-06-28 |
2001-05-22 |
Sontra Medical, Inc. |
Ultrasound enhancement of transdermal transport
|
US5939262A
(en)
|
1996-07-03 |
1999-08-17 |
Ambion, Inc. |
Ribonuclease resistant RNA preparation and utilization
|
US5677124A
(en)
|
1996-07-03 |
1997-10-14 |
Ambion, Inc. |
Ribonuclease resistant viral RNA standards
|
US7288266B2
(en)
|
1996-08-19 |
2007-10-30 |
United States Of America As Represented By The Secretary, Department Of Health And Human Services |
Liposome complexes for increased systemic delivery
|
US5849546A
(en)
|
1996-09-13 |
1998-12-15 |
Epicentre Technologies Corporation |
Methods for using mutant RNA polymerases with reduced discrimination between non-canonical and canonical nucleoside triphosphates
|
US6114148C1
(en)
|
1996-09-20 |
2012-05-01 |
Gen Hospital Corp |
High level expression of proteins
|
AU737323B2
(en)
|
1996-09-24 |
2001-08-16 |
Genentech, Inc. |
A family of genes encoding apoptosis-related peptides, peptides encoded thereby and methods of use thereof
|
US6214966B1
(en)
|
1996-09-26 |
2001-04-10 |
Shearwater Corporation |
Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution
|
AU4992197A
(en)
|
1996-10-11 |
1998-05-11 |
Regents Of The University Of California, The |
Immunostimulatory polynucleotide/immunomodulatory molecule conjugates
|
EP0839912A1
(en)
|
1996-10-30 |
1998-05-06 |
Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) |
Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
|
GB9623051D0
(en)
|
1996-11-06 |
1997-01-08 |
Schacht Etienne H |
Delivery of DNA to target cells in biological systems
|
US5980887A
(en)
|
1996-11-08 |
1999-11-09 |
St. Elizabeth's Medical Center Of Boston |
Methods for enhancing angiogenesis with endothelial progenitor cells
|
US5759179A
(en)
|
1996-12-31 |
1998-06-02 |
Johnson & Johnson Medical, Inc. |
Needle and valve assembly for use with a catheter
|
ATE332368T1
(de)
|
1997-01-21 |
2006-07-15 |
Gen Hospital Corp |
Selektion von proteinen mittels rns-protein fusionen
|
EP0855184A1
(en)
|
1997-01-23 |
1998-07-29 |
Grayson B. Dr. Lipford |
Pharmaceutical composition comprising a polynucleotide and an antigen especially for vaccination
|
JP2001512308A
(ja)
|
1997-02-07 |
2001-08-21 |
メルク エンド カンパニー インコーポレーテッド |
合成hiv gag遺伝子
|
US6228640B1
(en)
|
1997-02-07 |
2001-05-08 |
Cem Cezayirli |
Programmable antigen presenting cell of CD34 lineage
|
US6696291B2
(en)
|
1997-02-07 |
2004-02-24 |
Merck & Co., Inc. |
Synthetic HIV gag genes
|
US6251665B1
(en)
|
1997-02-07 |
2001-06-26 |
Cem Cezayirli |
Directed maturation of stem cells and production of programmable antigen presenting dentritic cells therefrom
|
US6576752B1
(en)
|
1997-02-14 |
2003-06-10 |
Isis Pharmaceuticals, Inc. |
Aminooxy functionalized oligomers
|
JP3756313B2
(ja)
|
1997-03-07 |
2006-03-15 |
武 今西 |
新規ビシクロヌクレオシド及びオリゴヌクレオチド類縁体
|
US6406705B1
(en)
|
1997-03-10 |
2002-06-18 |
University Of Iowa Research Foundation |
Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant
|
US6306393B1
(en)
|
1997-03-24 |
2001-10-23 |
Immunomedics, Inc. |
Immunotherapy of B-cell malignancies using anti-CD22 antibodies
|
US6261281B1
(en)
|
1997-04-03 |
2001-07-17 |
Electrofect As |
Method for genetic immunization and introduction of molecules into skeletal muscle and immune cells
|
US5914269A
(en)
|
1997-04-04 |
1999-06-22 |
Isis Pharmaceuticals, Inc. |
Oligonucleotide inhibition of epidermal growth factor receptor expression
|
WO1998047913A2
(en)
|
1997-04-18 |
1998-10-29 |
The University Of Medicine And Dentistry Of New Jersey |
Inhibition of hiv-1 replication by a tat rna-binding domain peptide analog
|
US5958688A
(en)
|
1997-04-28 |
1999-09-28 |
The Trustees Of The University Of Pennsylvania |
Characterization of mRNA patterns in neurites and single cells for medical diagnosis and therapeutics
|
US6235883B1
(en)
|
1997-05-05 |
2001-05-22 |
Abgenix, Inc. |
Human monoclonal antibodies to epidermal growth factor receptor
|
US5989911A
(en)
|
1997-05-09 |
1999-11-23 |
University Of Massachusetts |
Site-specific synthesis of pseudouridine in RNA
|
US6761726B1
(en)
|
1998-05-15 |
2004-07-13 |
Pyng Medical Corp. |
Method and apparatus for the intraosseous introduction of a device such as an infusion tube
|
US5993412A
(en)
|
1997-05-19 |
1999-11-30 |
Bioject, Inc. |
Injection apparatus
|
US6124091A
(en)
|
1997-05-30 |
2000-09-26 |
Research Corporation Technologies, Inc. |
Cell growth-controlling oligonucleotides
|
EP0986572B2
(en)
|
1997-06-06 |
2007-06-13 |
Dynavax Technologies Corporation |
Immunostimulatory oligonucleotides, compositions thereof and methods of use thereof
|
US6589940B1
(en)
|
1997-06-06 |
2003-07-08 |
Dynavax Technologies Corporation |
Immunostimulatory oligonucleotides, compositions thereof and methods of use thereof
|
CA2294988C
(en)
|
1997-07-01 |
2015-11-24 |
Isis Pharmaceuticals Inc. |
Compositions and methods for the delivery of oligonucleotides via the alimentary canal
|
US5994511A
(en)
|
1997-07-02 |
1999-11-30 |
Genentech, Inc. |
Anti-IgE antibodies and methods of improving polypeptides
|
ATE361102T1
(de)
|
1997-07-21 |
2007-05-15 |
Active Biotech Ab |
Zytolyse der geeigneten zielzellen mit superantigen konjugate mittels der induktion von t-zell aktivierung
|
US20030073640A1
(en)
|
1997-07-23 |
2003-04-17 |
Ribozyme Pharmaceuticals, Inc. |
Novel compositions for the delivery of negatively charged molecules
|
WO1999006073A1
(en)
|
1997-07-31 |
1999-02-11 |
St. Elizabeth's Medical Center Of Boston, Inc. |
Method for the treatment of grafts
|
US6794499B2
(en)
|
1997-09-12 |
2004-09-21 |
Exiqon A/S |
Oligonucleotide analogues
|
WO1999013896A1
(en)
|
1997-09-18 |
1999-03-25 |
The Trustees Of The University Of Pennsylvania |
Attenuated vif dna immunization cassettes for genetic vaccines
|
WO1999014346A2
(en)
|
1997-09-19 |
1999-03-25 |
Sequitur, Inc. |
SENSE mRNA THERAPY
|
US6004573A
(en)
|
1997-10-03 |
1999-12-21 |
Macromed, Inc. |
Biodegradable low molecular weight triblock poly(lactide-co-glycolide) polyethylene glycol copolymers having reverse thermal gelation properties
|
WO1999018221A1
(en)
|
1997-10-07 |
1999-04-15 |
University Of Maryland Biotechnology Institute |
Method for introducing and expressing rna in animal cells
|
CN1179048C
(zh)
|
1997-10-20 |
2004-12-08 |
Gtc生物治疗学公司 |
修饰的MSP-1核酸序列以及增加细胞系统中mRNA水平和蛋白质表达的方法
|
US6019747A
(en)
|
1997-10-21 |
2000-02-01 |
I-Flow Corporation |
Spring-actuated infusion syringe
|
JP2001520889A
(ja)
*
|
1997-10-24 |
2001-11-06 |
バレンティス,インコーポレイティド |
ポリヌクレオチドトランスフェクション複合体を調製する方法
|
US6077251A
(en)
|
1997-10-30 |
2000-06-20 |
Ting; Windsor |
Medicinal agent administration system
|
CA2309766C
(en)
|
1997-11-20 |
2008-09-30 |
Vical Incorporated |
Treatment of cancer using cytokine-expressing polynucleotides and compositions therefor
|
US7655777B2
(en)
|
1997-11-24 |
2010-02-02 |
Monsanto Technology Llc |
Nucleic acid molecules associated with the tocopherol pathway
|
AU1819499A
(en)
|
1997-12-12 |
1999-06-28 |
Samyang Corporation |
Positively-charged poly{alpha-(omega-aminoalkyl)glycolic acid} for the delivery of a bioactive agent via tissue and cellular uptake
|
US6517869B1
(en)
|
1997-12-12 |
2003-02-11 |
Expression Genetics, Inc. |
Positively charged poly(alpha-(omega-aminoalkyl)lycolic acid) for the delivery of a bioactive agent via tissue and cellular uptake
|
US6320017B1
(en)
|
1997-12-23 |
2001-11-20 |
Inex Pharmaceuticals Corp. |
Polyamide oligomers
|
JP2002500010A
(ja)
|
1997-12-23 |
2002-01-08 |
カイロン コーポレイション |
ヒト遺伝子および遺伝子発現産物i
|
US6383811B2
(en)
|
1997-12-30 |
2002-05-07 |
Mirus Corporation |
Polyampholytes for delivering polyions to a cell
|
WO1999034831A1
(en)
|
1998-01-05 |
1999-07-15 |
University Of Washington |
Enhanced transport using membrane disruptive agents
|
JP2002500075A
(ja)
|
1998-01-08 |
2002-01-08 |
ソントラ メディカル, インコーポレイテッド |
超音波伝達で増強される経皮輸送
|
US8287483B2
(en)
|
1998-01-08 |
2012-10-16 |
Echo Therapeutics, Inc. |
Method and apparatus for enhancement of transdermal transport
|
IT1298087B1
(it)
|
1998-01-08 |
1999-12-20 |
Fiderm S R L |
Dispositivo per il controllo della profondita' di penetrazione di un ago, in particolare applicabile ad una siringa per iniezioni
|
US6365346B1
(en)
|
1998-02-18 |
2002-04-02 |
Dade Behring Inc. |
Quantitative determination of nucleic acid amplification products
|
US5955310A
(en)
|
1998-02-26 |
1999-09-21 |
Novo Nordisk Biotech, Inc. |
Methods for producing a polypeptide in a bacillus cell
|
US6432925B1
(en)
|
1998-04-16 |
2002-08-13 |
John Wayne Cancer Institute |
RNA cancer vaccine and methods for its use
|
US6429301B1
(en)
|
1998-04-17 |
2002-08-06 |
Whitehead Institute For Biomedical Research |
Use of a ribozyme to join nucleic acids and peptides
|
GB9808327D0
(en)
|
1998-04-20 |
1998-06-17 |
Chiron Spa |
Antidiotypic compounds
|
AU3534199A
(en)
|
1998-04-23 |
1999-11-08 |
Takara Shuzo Co., Ltd. |
Method For Synthesizing DNA
|
US6395253B2
(en)
*
|
1998-04-23 |
2002-05-28 |
The Regents Of The University Of Michigan |
Microspheres containing condensed polyanionic bioactive agents and methods for their production
|
US20020064517A1
(en)
*
|
1998-04-30 |
2002-05-30 |
Stewart A. Cederholm-Williams |
Fibrin sealant as a transfection/transformation vehicle for gene therapy
|
US20090208418A1
(en)
|
2005-04-29 |
2009-08-20 |
Innexus Biotechnology Internaltional Ltd. |
Superantibody synthesis and use in detection, prevention and treatment of disease
|
CN1333678A
(zh)
|
1998-05-20 |
2002-01-30 |
表达遗传学公司 |
定向肝细胞的聚乙二醇接枝的聚-l-赖氨酸的聚合基因载体
|
US6503231B1
(en)
|
1998-06-10 |
2003-01-07 |
Georgia Tech Research Corporation |
Microneedle device for transport of molecules across tissue
|
US7091192B1
(en)
|
1998-07-01 |
2006-08-15 |
California Institute Of Technology |
Linear cyclodextrin copolymers
|
EP1100579B1
(en)
|
1998-07-13 |
2015-09-02 |
Inovio Pharmaceuticals, Inc. |
Skin and muscle-targeted gene therapy by pulsed electrical field
|
KR20010079526A
(ko)
|
1998-07-13 |
2001-08-22 |
추후제출 |
용해성 생분해 유전자 전달 담체인 폴리-l-리신의폴리에스테르 유사체
|
US6222030B1
(en)
|
1998-08-03 |
2001-04-24 |
Agilent Technologies, Inc. |
Solid phase synthesis of oligonucleotides using carbonate protecting groups and alpha-effect nucleophile deprotection
|
ES2388893T3
(es)
|
1998-08-11 |
2012-10-19 |
Biogen Idec Inc. |
Terapias de combinación para linfomas de células B que comprenden la administración de anticuerpos anti-CD20
|
GB9817662D0
(en)
|
1998-08-13 |
1998-10-07 |
Crocker Peter J |
Substance delivery
|
US20020065236A1
(en)
|
1998-09-09 |
2002-05-30 |
Yew Nelson S. |
CpG reduced plasmids and viral vectors
|
US20090042283A1
(en)
|
1998-09-29 |
2009-02-12 |
Shire Human Genetic Therapies, Inc., A Delaware Corporation |
Optimized messenger rna
|
US6924365B1
(en)
|
1998-09-29 |
2005-08-02 |
Transkaryotic Therapies, Inc. |
Optimized messenger RNA
|
WO2000026226A1
(en)
|
1998-11-03 |
2000-05-11 |
Yale University |
Multidomain polynucleotide molecular sensors
|
MXPA01004649A
(es)
|
1998-11-09 |
2002-05-06 |
Idec Pharma Corp |
Tratamiento con anticuerpo quimerico anti-cd20 para pacientes que reciben transplantes de medula osea o celulas madre de sangre periferica.
|
ES2351149T3
(es)
|
1998-11-09 |
2011-02-01 |
Biogen Idec Inc. |
Anticuerpo quimérico dirigido contra cd20, el rituxan, para uso en el tratamiento de la leucemia linfocítica crónica.
|
AU2023400A
(en)
|
1998-11-12 |
2000-05-29 |
Children's Medical Center Corporation |
Compositions and methods for inhibiting angiogenesis using trna and fragments thereof
|
EP1129064B1
(en)
|
1998-11-12 |
2008-01-09 |
Invitrogen Corporation |
Transfection reagents
|
US6210931B1
(en)
|
1998-11-30 |
2001-04-03 |
The United States Of America As Represented By The Secretary Of Agriculture |
Ribozyme-mediated synthesis of circular RNA
|
US20040171980A1
(en)
|
1998-12-18 |
2004-09-02 |
Sontra Medical, Inc. |
Method and apparatus for enhancement of transdermal transport
|
CA2356542A1
(en)
|
1998-12-23 |
2000-07-06 |
Human Genome Sciences, Inc. |
Peptidoglycan recognition proteins
|
GB9902000D0
(en)
|
1999-01-30 |
1999-03-17 |
Delta Biotechnology Ltd |
Process
|
WO2000050586A2
(en)
|
1999-02-22 |
2000-08-31 |
European Molecular Biology Laboratory |
In vitro translation system
|
US6255476B1
(en)
|
1999-02-22 |
2001-07-03 |
Pe Corporation (Ny) |
Methods and compositions for synthesis of labelled oligonucleotides and analogs on solid-supports
|
US7629311B2
(en)
|
1999-02-24 |
2009-12-08 |
Edward Lewis Tobinick |
Methods to facilitate transmission of large molecules across the blood-brain, blood-eye, and blood-nerve barriers
|
EP1574210B1
(en)
|
1999-02-26 |
2016-04-06 |
Novartis Vaccines and Diagnostics, Inc. |
Microemulsions with adsorbed macromolecules
|
WO2000051666A1
(en)
|
1999-03-01 |
2000-09-08 |
Pro Duct Health, Inc. |
Apparatus, methods and kits for simultaneous delivery of a substance to multiple breast milk ducts
|
US7084125B2
(en)
|
1999-03-18 |
2006-08-01 |
Exiqon A/S |
Xylo-LNA analogues
|
CA2369119A1
(en)
|
1999-03-29 |
2000-05-25 |
Statens Serum Institut |
Nucleotide construct with optimised codons for an hiv genetic vaccine based on a primary, early hiv isolate and synthetic envelope
|
US7217762B1
(en)
|
1999-04-09 |
2007-05-15 |
Invitrogen Corporation |
Process for the preparation of monodisperse polymer particles
|
EP1178999B1
(en)
|
1999-05-04 |
2007-03-14 |
Santaris Pharma A/S |
L-ribo-lna analogues
|
KR20080039550A
(ko)
|
1999-05-07 |
2008-05-07 |
제넨테크, 인크. |
B 세포 표면 마커에 결합하는 길항물질을 이용한 자가면역질환의 치료
|
KR20020011985A
(ko)
|
1999-05-07 |
2002-02-09 |
파르마솔 게엠베하 |
액상 및 고체상 지질 혼합물에 기초한 지질입자들 및 그의제조방법
|
US7074403B1
(en)
|
1999-06-09 |
2006-07-11 |
Immunomedics, Inc. |
Immunotherapy of autoimmune disorders using antibodies which target B-cells
|
US7171264B1
(en)
|
1999-05-10 |
2007-01-30 |
Genetronics, Inc. |
Intradermal delivery of active agents by needle-free injection and electroporation
|
US6346382B1
(en)
|
1999-06-01 |
2002-02-12 |
Vanderbilt University |
Human carbamyl phosphate synthetase I polymorphism and diagnostic methods related thereto
|
AU4332399A
(en)
|
1999-06-04 |
2000-12-28 |
Cheng-Ming Chuong |
Rna polymerase chain reaction
|
US6743211B1
(en)
|
1999-11-23 |
2004-06-01 |
Georgia Tech Research Corporation |
Devices and methods for enhanced microneedle penetration of biological barriers
|
US6611707B1
(en)
|
1999-06-04 |
2003-08-26 |
Georgia Tech Research Corporation |
Microneedle drug delivery device
|
US6303573B1
(en)
|
1999-06-07 |
2001-10-16 |
The Burnham Institute |
Heart homing peptides and methods of using same
|
CA2376634A1
(en)
|
1999-06-08 |
2000-12-14 |
Aventis Pasteur |
Immunostimulant oligonucleotide
|
US6949245B1
(en)
|
1999-06-25 |
2005-09-27 |
Genentech, Inc. |
Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies
|
JP2003503071A
(ja)
|
1999-06-30 |
2003-01-28 |
アドバンスド セル テクノロジー、インコーポレイテッド |
脱分化レシピエント細胞への細胞質移入
|
US6514948B1
(en)
|
1999-07-02 |
2003-02-04 |
The Regents Of The University Of California |
Method for enhancing an immune response
|
BR0012325A
(pt)
|
1999-07-09 |
2002-05-21 |
American Home Prod |
Métodos e composições para prevenção da formação de rna anormal durante a transcrição de uma sequência de plasmìdeo
|
US8557244B1
(en)
|
1999-08-11 |
2013-10-15 |
Biogen Idec Inc. |
Treatment of aggressive non-Hodgkins lymphoma with anti-CD20 antibody
|
CN1371416B
(zh)
|
1999-08-24 |
2012-10-10 |
梅达里克斯公司 |
人ctla-4抗体及其应用
|
US20050112141A1
(en)
|
2000-08-30 |
2005-05-26 |
Terman David S. |
Compositions and methods for treatment of neoplastic disease
|
US6551338B1
(en)
|
1999-09-01 |
2003-04-22 |
Mcgill University |
Method and device for myogenesis and angiogenesis of the heart
|
US20040106567A1
(en)
|
1999-09-07 |
2004-06-03 |
Hagstrom James E. |
Intravascular delivery of non-viral nucleic acid
|
DE69943068D1
(de)
|
1999-09-09 |
2011-02-03 |
Curevac Gmbh |
Transfer von mRNA unter Verwendung von polykationischen Verbindungen
|
WO2001021810A1
(en)
|
1999-09-17 |
2001-03-29 |
Aventis Pasteur Limited |
Chlamydia antigens and corresponding dna fragments and uses thereof
|
US6623457B1
(en)
|
1999-09-22 |
2003-09-23 |
Becton, Dickinson And Company |
Method and apparatus for the transdermal administration of a substance
|
WO2002064799A2
(en)
|
1999-09-28 |
2002-08-22 |
Transkaryotic Therapies, Inc. |
Optimized messenger rna
|
WO2001025488A2
(en)
|
1999-10-06 |
2001-04-12 |
Quark Biotech, Inc. |
Method for enrichment of natural antisense messenger rna
|
US7060291B1
(en)
|
1999-11-24 |
2006-06-13 |
Transave, Inc. |
Modular targeted liposomal delivery system
|
US6613026B1
(en)
|
1999-12-08 |
2003-09-02 |
Scimed Life Systems, Inc. |
Lateral needle-less injection apparatus and method
|
US6277974B1
(en)
|
1999-12-14 |
2001-08-21 |
Cogent Neuroscience, Inc. |
Compositions and methods for diagnosing and treating conditions, disorders, or diseases involving cell death
|
US6245929B1
(en)
|
1999-12-20 |
2001-06-12 |
General Electric Company |
Catalyst composition and method for producing diaryl carbonates, using bisphosphines
|
ES2230173T3
(es)
|
1999-12-22 |
2005-05-01 |
Basell Poliolefine Italia S.P.A. |
Sistema catalizador para la polimerizacion de alfa olefinas el cual contiene un compuesto aromatico de silano.
|
SE515932C2
(sv)
|
1999-12-23 |
2001-10-29 |
Prostalund Operations Ab |
Sätt och anordning vid behandling av prostata
|
AU2764801A
(en)
|
2000-01-07 |
2001-07-24 |
University Of Washington |
Enhanced transport of agents using membrane disruptive agents
|
AU2001232485A1
(en)
|
2000-01-13 |
2001-07-24 |
Amsterdam Support Diagnostics B.V. |
A universal nucleic acid amplification system for nucleic acids in a sample
|
WO2001055341A2
(en)
|
2000-01-31 |
2001-08-02 |
The Regents Of The University Of California |
Immunomodulatory polynucleotides in treatment of an infection by an intracellular pathogen
|
WO2001055306A2
(en)
|
2000-01-31 |
2001-08-02 |
Human Genome Sciences, Inc. |
Nucleic acids, proteins, and antibodies
|
US7491805B2
(en)
|
2001-05-18 |
2009-02-17 |
Sirna Therapeutics, Inc. |
Conjugates and compositions for cellular delivery
|
US7833992B2
(en)
|
2001-05-18 |
2010-11-16 |
Merck Sharpe & Dohme |
Conjugates and compositions for cellular delivery
|
AU2001238595A1
(en)
|
2000-02-22 |
2001-09-03 |
Shearwater Corporation |
N-maleimidyl polymer derivatives
|
IL151378A0
(en)
|
2000-02-24 |
2003-04-10 |
Univ Washington |
Humanized antibodies that sequester amyloid beta peptide
|
BR0108962A
(pt)
|
2000-03-03 |
2002-12-24 |
Valentis Inc |
Formulações de ácido nucléico para distribuição de genes e métodos de uso
|
AU8729101A
(en)
|
2000-03-31 |
2001-10-15 |
Idec Pharma Corp |
Combined use of anti-cytokine antibodies or antagonists and anti-CD20 for the treatment of B cell lymphoma
|
WO2001075166A2
(en)
|
2000-03-31 |
2001-10-11 |
Genentech, Inc. |
Compositions and methods for detecting and quantifying gene expression
|
US6565572B2
(en)
|
2000-04-10 |
2003-05-20 |
Sdgi Holdings, Inc. |
Fenestrated surgical screw and method
|
US6368801B1
(en)
|
2000-04-12 |
2002-04-09 |
Molecular Staging, Inc. |
Detection and amplification of RNA using target-mediated ligation of DNA by RNA ligase
|
CA2405563A1
(en)
|
2000-04-12 |
2001-10-25 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
US20010046496A1
(en)
|
2000-04-14 |
2001-11-29 |
Brettman Lee R. |
Method of administering an antibody
|
US6468247B1
(en)
|
2000-04-21 |
2002-10-22 |
Mark Zamoyski |
Perfusion device for localized drug delivery
|
US6375972B1
(en)
|
2000-04-26 |
2002-04-23 |
Control Delivery Systems, Inc. |
Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
|
US7871598B1
(en)
|
2000-05-10 |
2011-01-18 |
Novartis Ag |
Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
|
US20040229271A1
(en)
|
2000-05-19 |
2004-11-18 |
Williams Richard B. |
Compositions and methods for the identification and selection of nucleic acids and polypeptides
|
WO2001092523A2
(en)
|
2000-05-30 |
2001-12-06 |
Curagen Corporation |
Human polynucleotides and polypeptides encoded thereby
|
US6537242B1
(en)
|
2000-06-06 |
2003-03-25 |
Becton, Dickinson And Company |
Method and apparatus for enhancing penetration of a member for the intradermal sampling or administration of a substance
|
EP1292331A2
(en)
|
2000-06-07 |
2003-03-19 |
Biosynexus Incorporated |
Immunostimulatory rna/dna hybrid molecules
|
US6607513B1
(en)
|
2000-06-08 |
2003-08-19 |
Becton, Dickinson And Company |
Device for withdrawing or administering a substance and method of manufacturing a device
|
ES2273852T3
(es)
|
2000-06-23 |
2007-05-16 |
Wyeth Holdings Corporation |
Proteinas v de morbillivirus modificadas.
|
US20050181033A1
(en)
|
2000-06-29 |
2005-08-18 |
Dekker John P.Iii |
Method for delivering interferons to the intradermal compartment
|
DE60139690D1
(de)
|
2000-07-03 |
2009-10-08 |
Novartis Vaccines & Diagnostic |
Immunisierung gegen chlamydia pneumoniae
|
US6440096B1
(en)
|
2000-07-14 |
2002-08-27 |
Becton, Dickinson And Co. |
Microdevice and method of manufacturing a microdevice
|
DE60124918T2
(de)
|
2000-07-21 |
2007-08-02 |
Glaxo Group Ltd., Greenford |
Kodon-optimierte papillomavirussequenzen
|
US6902734B2
(en)
|
2000-08-07 |
2005-06-07 |
Centocor, Inc. |
Anti-IL-12 antibodies and compositions thereof
|
US20040142474A1
(en)
|
2000-09-14 |
2004-07-22 |
Expression Genetics, Inc. |
Novel cationic lipopolymer as a biocompatible gene delivery agent
|
US6696038B1
(en)
|
2000-09-14 |
2004-02-24 |
Expression Genetics, Inc. |
Cationic lipopolymer as biocompatible gene delivery agent
|
UA83458C2
(uk)
*
|
2000-09-18 |
2008-07-25 |
Байоджен Айдек Ма Інк. |
Виділений поліпептид baff-r (рецептор фактора активації в-клітин сімейства tnf)
|
AU2001290078A1
(en)
|
2000-09-20 |
2002-04-02 |
Ruggero Della Bitta |
Stem cell therapy
|
DE60119562T2
(de)
|
2000-10-04 |
2007-05-10 |
Santaris Pharma A/S |
Verbesserte synthese von purin-blockierten nukleinsäure-analoga
|
CA2424216A1
(en)
|
2000-10-04 |
2002-04-11 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods of using capsid protein from flaviviruses and pestiviruses
|
US6998115B2
(en)
|
2000-10-10 |
2006-02-14 |
Massachusetts Institute Of Technology |
Biodegradable poly(β-amino esters) and uses thereof
|
US6649138B2
(en)
|
2000-10-13 |
2003-11-18 |
Quantum Dot Corporation |
Surface-modified semiconductive and metallic nanoparticles having enhanced dispersibility in aqueous media
|
US7202226B2
(en)
|
2000-10-23 |
2007-04-10 |
Detroit R & D |
Augmentation of wound healing by elF-4E mRNA and EGF mRNA
|
US20030077604A1
(en)
|
2000-10-27 |
2003-04-24 |
Yongming Sun |
Compositions and methods relating to breast specific genes and proteins
|
ATE537845T1
(de)
*
|
2000-10-31 |
2012-01-15 |
Pr Pharmaceuticals Inc |
Verfahren zur herstellung von formulierungen zur verbesserten abgabe von bioaktiven molekülen
|
US20020132788A1
(en)
|
2000-11-06 |
2002-09-19 |
David Lewis |
Inhibition of gene expression by delivery of small interfering RNA to post-embryonic animal cells in vivo
|
WO2002040545A2
(en)
|
2000-11-17 |
2002-05-23 |
The Government Of The United States, As Represented By The Secretary Of The Department Of Health And Human Services |
Reduction of the nonspecific animal toxicity of immunotoxins by mutating the framework regions of the fv to lower the isoelectric point
|
EP1415005B1
(en)
|
2000-12-07 |
2012-11-21 |
Novartis Vaccines and Diagnostics, Inc. |
Endogenous retroviruses up-regulated in prostate cancer
|
US20020130430A1
(en)
*
|
2000-12-29 |
2002-09-19 |
Castor Trevor Percival |
Methods for making polymer microspheres/nanospheres and encapsulating therapeutic proteins and other products
|
US7708915B2
(en)
|
2004-05-06 |
2010-05-04 |
Castor Trevor P |
Polymer microspheres/nanospheres and encapsulating therapeutic proteins therein
|
US7628780B2
(en)
|
2001-01-13 |
2009-12-08 |
Medtronic, Inc. |
Devices and methods for interstitial injection of biologic agents into tissue
|
KR20040002853A
(ko)
|
2001-01-19 |
2004-01-07 |
비로노바티브 비.브이. |
감응성 포유류에서 호흡계 질환을 유발하는 바이러스
|
EP1224943A1
(en)
|
2001-01-19 |
2002-07-24 |
Crucell Holland B.V. |
Fibronectin as a tumor marker detected by phage antibodies
|
US20040110191A1
(en)
|
2001-01-31 |
2004-06-10 |
Winkler Matthew M. |
Comparative analysis of nucleic acids using population tagging
|
CA2437737A1
(en)
|
2001-02-14 |
2002-08-22 |
Stephen D. Ginsberg |
Methods and compositions of amplifying rna
|
US6652886B2
(en)
|
2001-02-16 |
2003-11-25 |
Expression Genetics |
Biodegradable cationic copolymers of poly (alkylenimine) and poly (ethylene glycol) for the delivery of bioactive agents
|
DE10109897A1
(de)
|
2001-02-21 |
2002-11-07 |
Novosom Ag |
Fakultativ kationische Liposomen und Verwendung dieser
|
US7232425B2
(en)
|
2001-03-02 |
2007-06-19 |
Sorenson Development, Inc. |
Apparatus and method for specific interstitial or subcutaneous diffusion and dispersion of medication
|
DE60228212D1
(de)
|
2001-03-09 |
2008-09-25 |
Gene Stream Pty Ltd |
Neue expressionsvektoren
|
JP2002262882A
(ja)
|
2001-03-12 |
2002-09-17 |
Nisshinbo Ind Inc |
Rnaの増幅法
|
FR2822164B1
(fr)
|
2001-03-19 |
2004-06-18 |
Centre Nat Rech Scient |
Polypeptides derives des arn polymerases, et leurs utilisations
|
US6520949B2
(en)
|
2001-04-02 |
2003-02-18 |
Martin St. Germain |
Method and apparatus for administering fluid to animals subcutaneously
|
US6625486B2
(en)
|
2001-04-11 |
2003-09-23 |
Advanced Cardiovascular Systems, Inc. |
Method and apparatus for intracellular delivery of an agent
|
DE10119005A1
(de)
|
2001-04-18 |
2002-10-24 |
Roche Diagnostics Gmbh |
Verfahren zur Proteinexpression ausgehend von stabilisierter linearer kurzer DNA in zellfreien in vitro-Transkription/Translations-Systemen mit Exonuklease-haltigen Lysaten oder in einem zellulären System enthaltend Exonukleasen
|
US20030171253A1
(en)
|
2001-04-19 |
2003-09-11 |
Averil Ma |
Methods and compositions relating to modulation of A20
|
DE50211110D1
(de)
|
2001-04-21 |
2007-12-06 |
Curevac Gmbh |
INJEKTIONSGERÄT FÜR mRNA APPLIKATION
|
WO2002086134A2
(de)
|
2001-04-23 |
2002-10-31 |
Amaxa Gmbh |
Pufferlössung für die elektroporation und verfahren umfassend die verwendung derselben
|
US7560424B2
(en)
|
2001-04-30 |
2009-07-14 |
Zystor Therapeutics, Inc. |
Targeted therapeutic proteins
|
US6777187B2
(en)
|
2001-05-02 |
2004-08-17 |
Rubicon Genomics, Inc. |
Genome walking by selective amplification of nick-translate DNA library and amplification from complex mixtures of templates
|
AU2002308623A1
(en)
|
2001-05-08 |
2002-11-18 |
Magnatech International, L.P. |
Electronic length control wire pay-off system and method
|
US20050137155A1
(en)
|
2001-05-18 |
2005-06-23 |
Sirna Therapeutics, Inc. |
RNA interference mediated treatment of Parkinson disease using short interfering nucleic acid (siNA)
|
US8137911B2
(en)
|
2001-05-22 |
2012-03-20 |
Cellscript, Inc. |
Preparation and use of single-stranded transcription substrates for synthesis of transcription products corresponding to target sequences
|
US7514098B2
(en)
|
2001-05-30 |
2009-04-07 |
The Board Of Trustees Of The Leland Stanford Junior University |
Use of targeted cross-linked nanoparticles for in vivo gene delivery
|
EP1832603B1
(de)
|
2001-06-05 |
2010-02-03 |
CureVac GmbH |
Stabilisierte mRNA mit erhöhtem G/C-Gehalt, enkodierend für ein bakterielles Antigen sowie deren Verwendung
|
US20040175787A1
(en)
|
2001-06-18 |
2004-09-09 |
Klemens Kaupmann |
Novel g-protein coupled receptors and dna sequences thereof
|
US7547551B2
(en)
|
2001-06-21 |
2009-06-16 |
University Of Antwerp. |
Transfection of eukaryontic cells with linear polynucleotides by electroporation
|
US7785610B2
(en)
|
2001-06-21 |
2010-08-31 |
Dynavax Technologies Corporation |
Chimeric immunomodulatory compounds and methods of using the same—III
|
EP1270732A1
(en)
|
2001-06-21 |
2003-01-02 |
Schuler, Gerold |
Improved transfection of eukaryontic cells with linear polynucleotides by electroporation
|
JP2005503137A
(ja)
|
2001-06-26 |
2005-02-03 |
ノバルティス アクチエンゲゼルシャフト |
Gタンパク質共役レセプターおよびそのdna配列
|
SE0102327D0
(sv)
|
2001-06-28 |
2001-06-28 |
Active Biotech Ab |
A novel engineered superantigen for human therapy
|
MXPA03011611A
(es)
|
2001-06-29 |
2004-07-01 |
Becton Dickinson Co |
Administracion intradermica de vacunas y agentes terapeuticos genicos a traves de microcanula.
|
US20040236092A1
(en)
|
2001-07-13 |
2004-11-25 |
Roman Dziarski |
Peptidologlycan recognition protein encoding nucleic acids and methods of use thereof
|
US6586524B2
(en)
|
2001-07-19 |
2003-07-01 |
Expression Genetics, Inc. |
Cellular targeting poly(ethylene glycol)-grafted polymeric gene carrier
|
US7169750B2
(en)
|
2001-07-31 |
2007-01-30 |
Anormed, Inc. |
Methods to mobilize progenitor/stem cells
|
AU2002312543A1
(en)
|
2001-08-01 |
2003-02-17 |
University Of Utah, Technology Transfer Office |
Isoform-selective inhibitors and activators of pde3 cyclic
|
AU2002331181A1
(en)
|
2001-08-27 |
2003-03-10 |
Novartis Ag |
G-protein coupled receptor and dna sequences thereof
|
US20040142325A1
(en)
|
2001-09-14 |
2004-07-22 |
Liat Mintz |
Methods and systems for annotating biomolecular sequences
|
EP2428569B1
(en)
|
2001-09-28 |
2018-05-23 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Microrna molecules
|
EP1443905A4
(en)
|
2001-10-03 |
2010-06-23 |
Univ Johns Hopkins |
COMPOSITIONS FOR ORAL GENE THERAPY AND METHOD OF USE THEREOF
|
AR045702A1
(es)
|
2001-10-03 |
2005-11-09 |
Chiron Corp |
Composiciones de adyuvantes.
|
DE10148886A1
(de)
|
2001-10-04 |
2003-04-30 |
Avontec Gmbh |
Inhibition von STAT-1
|
US7276489B2
(en)
|
2002-10-24 |
2007-10-02 |
Idera Pharmaceuticals, Inc. |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5′ ends
|
US7429258B2
(en)
|
2001-10-26 |
2008-09-30 |
Massachusetts Institute Of Technology |
Microneedle transport device
|
EP1452593B1
(en)
|
2001-11-14 |
2009-04-08 |
Toyo Boseki Kabushiki Kaisha |
Dna synthesis promoters, dna polymerase-associated factors and utilization thereof
|
US20030138419A1
(en)
|
2001-11-16 |
2003-07-24 |
The University Of Tennessee Research Corporation |
Recombinant antibody fusion proteins and methods for detection of apoptotic cells
|
WO2003046578A2
(en)
|
2001-11-29 |
2003-06-05 |
Novartis Ag |
Method for the assessment and prognosis of sarcoidosis
|
CA2409775C
(en)
|
2001-12-03 |
2010-07-13 |
F. Hoffmann-La Roche Ag |
Reversibly modified thermostable enzymes for dna synthesis and amplification in vitro
|
WO2003050258A2
(en)
|
2001-12-07 |
2003-06-19 |
Chiron Corporation |
Endogenous retrovirus polypeptides linked to oncogenic transformation
|
JP4646315B2
(ja)
|
2001-12-07 |
2011-03-09 |
ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド |
前立腺癌においてアップレギュレートされた内因性レトロウイルス
|
US20060275747A1
(en)
|
2001-12-07 |
2006-12-07 |
Hardy Stephen F |
Endogenous retrovirus up-regulated in prostate cancer
|
EP1458755A2
(en)
|
2001-12-17 |
2004-09-22 |
Novartis AG |
Novel g-protein coupled receptors and dna sequences thereof
|
DE10162480A1
(de)
|
2001-12-19 |
2003-08-07 |
Ingmar Hoerr |
Die Applikation von mRNA für den Einsatz als Therapeutikum gegen Tumorerkrankungen
|
PL211494B1
(pl)
|
2001-12-21 |
2012-05-31 |
Alcon |
Zastosowanie syntetycznych, nieorganicznych nanocząstek jako nośników dla leków i kompozycja farmaceutyczna do oczu lub uszu
|
WO2003059381A2
(en)
|
2002-01-18 |
2003-07-24 |
Curevac Gmbh |
Immunogenic preparations and vaccines on the basis of mrna
|
JP2005526497A
(ja)
|
2002-02-04 |
2005-09-08 |
ビオミラ,インコーポレーテッド |
免疫刺激性、共有結合性脂質化オリゴヌクレオチド
|
AU2003210802B2
(en)
|
2002-02-05 |
2009-09-10 |
Genentech Inc. |
Protein purification
|
FR2835749B1
(fr)
|
2002-02-08 |
2006-04-14 |
Inst Nat Sante Rech Med |
Composition pharmaceutique ameliorant le transfert de gene in vivo
|
DE10207178A1
(de)
|
2002-02-19 |
2003-09-04 |
Novosom Ag |
Komponenten für die Herstellung amphoterer Liposomen
|
AR038568A1
(es)
|
2002-02-20 |
2005-01-19 |
Hoffmann La Roche |
Anticuerpos anti-a beta y su uso
|
US20050222064A1
(en)
|
2002-02-20 |
2005-10-06 |
Sirna Therapeutics, Inc. |
Polycationic compositions for cellular delivery of polynucleotides
|
US7354742B2
(en)
|
2002-02-22 |
2008-04-08 |
Ortho-Mcneil Pharmaceutical, Inc. |
Method for generating amplified RNA
|
NZ535690A
(en)
|
2002-02-26 |
2009-04-30 |
Maxygen Inc |
Novel flavivirus antigens
|
PT1916001E
(pt)
|
2002-03-04 |
2011-07-18 |
Imclone Llc |
Anticorpos humanos específicos para kdr e suas utilizações
|
AU2003221497A1
(en)
|
2002-03-13 |
2003-09-22 |
Novartis Ag |
Pharmaceutical microparticles
|
US7074596B2
(en)
|
2002-03-25 |
2006-07-11 |
Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College |
Synthesis and use of anti-reverse mRNA cap analogues
|
US8153141B2
(en)
|
2002-04-04 |
2012-04-10 |
Coley Pharmaceutical Gmbh |
Immunostimulatory G, U-containing oligoribonucleotides
|
EP1497327A2
(en)
|
2002-04-17 |
2005-01-19 |
Novartis AG |
Method for the identification of inhibitors of the binding of are-containing mrna and an hur protein
|
GB0209539D0
(en)
|
2002-04-26 |
2002-06-05 |
Avecia Ltd |
Monomer Polymer and process
|
EP1361277A1
(en)
|
2002-04-30 |
2003-11-12 |
Centre National De La Recherche Scientifique (Cnrs) |
Optimization of transgene expression in mammalian cells
|
WO2003092665A2
(en)
|
2002-05-02 |
2003-11-13 |
Massachusetts Eye And Ear Infirmary |
Ocular drug delivery systems and use thereof
|
NZ573563A
(en)
|
2002-05-02 |
2010-10-29 |
Wyeth Corp |
Calicheamicin derivative-carrier conjugates with reduced low conjugated fraction (LCF)
|
EP3375463A1
(en)
|
2002-05-06 |
2018-09-19 |
Becton, Dickinson and Company |
Method and device for controlling drug pharmacokinetics
|
AU2003237824B9
(en)
|
2002-05-08 |
2008-06-19 |
The Regents Of The University Of California |
System and method for treating cardiac arrhythmias with fibroblast cells
|
US7374930B2
(en)
|
2002-05-21 |
2008-05-20 |
Expression Genetics, Inc. |
GLP-1 gene delivery for the treatment of type 2 diabetes
|
US20040018525A1
(en)
|
2002-05-21 |
2004-01-29 |
Bayer Aktiengesellschaft |
Methods and compositions for the prediction, diagnosis, prognosis, prevention and treatment of malignant neoplasma
|
DE10224200C1
(de)
|
2002-05-31 |
2003-08-21 |
Artus Ges Fuer Molekularbiolog |
Vermehrung von Ribonukleinsäuren
|
AU2003237367A1
(en)
|
2002-06-03 |
2003-12-19 |
Chiron Corporation |
Use of nrg4, or inhibitors thereof, in the treatment of colon and pancreatic cancer
|
SE0201907D0
(sv)
|
2002-06-19 |
2002-06-19 |
Atos Medical Ab |
Plaster for tracheostoma valves
|
ES2354607T3
(es)
|
2002-06-28 |
2011-03-16 |
Protiva Biotherapeutics Inc. |
Procedimiento y aparato para producir liposomas.
|
AU2003251770B9
(en)
|
2002-07-01 |
2009-06-04 |
H. Lundbeck A/S |
Recombinant tissue protective cytokines and encoding nucleic acids thereof for protection, restoration, and enhancement of responsive cells, tissues, and organs
|
DE10229872A1
(de)
|
2002-07-03 |
2004-01-29 |
Curevac Gmbh |
Immunstimulation durch chemisch modifizierte RNA
|
GB0215509D0
(en)
|
2002-07-04 |
2002-08-14 |
Novartis Ag |
Marker genes
|
US20040009180A1
(en)
|
2002-07-11 |
2004-01-15 |
Allergan, Inc. |
Transdermal botulinum toxin compositions
|
AR040575A1
(es)
|
2002-07-16 |
2005-04-13 |
Advisys Inc |
Plasmidos sinteticos optimizados en codones de expresion en mamiferos
|
AU2003252136A1
(en)
|
2002-07-24 |
2004-02-09 |
Ptc Therapeutics, Inc. |
METHODS FOR IDENTIFYING SMALL MOLEDULES THAT MODULATE PREMATURE TRANSLATION TERMINATION AND NONSENSE MEDIATED mRNA DECAY
|
EP1393745A1
(en)
|
2002-07-29 |
2004-03-03 |
Hybridon, Inc. |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5'ends
|
EP1386925A1
(en)
|
2002-07-31 |
2004-02-04 |
Girindus AG |
Method for preparing oligonucleotides
|
US6653468B1
(en)
|
2002-07-31 |
2003-11-25 |
Isis Pharmaceuticals, Inc. |
Universal support media for synthesis of oligomeric compounds
|
DE60325791D1
(de)
|
2002-08-01 |
2009-02-26 |
Abbott Lab Vascular Entpr Ltd |
Einspritzgerät zum Abdichten von Punkturwunden
|
EP1873180B1
(en)
|
2002-08-14 |
2014-05-07 |
Novartis AG |
Ophthalmic device made from a radiation-curable prepolymer
|
US20040082934A1
(en)
|
2002-08-30 |
2004-04-29 |
Pettis Ronald J. |
Method of controlling pharmacokinetics of immunomodulatory compounds
|
ES2377318T3
(es)
|
2002-09-06 |
2012-03-26 |
Cerulean Pharma Inc. |
Polímeros a base de ciclodextrina para el suministro de los agentes terapéuticos enlazados covalentemente a ellos
|
ATE412684T1
(de)
|
2002-09-09 |
2008-11-15 |
Nektar Therapeutics Al Corp |
Verfahren zur herstellung von wasserlöslichen polymerderivaten mit terminalen carboxylgruppen
|
WO2004024067A2
(en)
|
2002-09-10 |
2004-03-25 |
Vical Incorporated |
Codon-optimized polynucleotide-based vaccines against bacillus anthracis infection
|
US7534872B2
(en)
|
2002-09-27 |
2009-05-19 |
Syngen, Inc. |
Compositions and methods for the use of FMOC derivatives in DNA/RNA synthesis
|
CN101928344B
(zh)
|
2002-10-17 |
2014-08-13 |
根马布股份公司 |
抗cd20的人单克隆抗体
|
WO2004038018A1
(ja)
|
2002-10-22 |
2004-05-06 |
Eisai Co., Ltd. |
分裂停止後のドーパミン産生ニューロン前駆細胞に特異的に発現している遺伝子
|
US6896666B2
(en)
|
2002-11-08 |
2005-05-24 |
Kochamba Family Trust |
Cutaneous injection delivery under suction
|
EP1567675A4
(en)
|
2002-11-21 |
2006-05-10 |
Epict Technologies |
METHODS OF USING PRIMERS THAT CODE A STRAND OF A BICATENARY PROMOTER
|
US7491234B2
(en)
|
2002-12-03 |
2009-02-17 |
Boston Scientific Scimed, Inc. |
Medical devices for delivery of therapeutic agents
|
US20040172127A1
(en)
|
2002-12-09 |
2004-09-02 |
John Kantor |
Modular stent having polymer bridges at modular unit contact sites
|
HU227217B1
(en)
|
2002-12-16 |
2010-11-29 |
Genentech Inc |
Immunoglobulin variants and uses thereof
|
WO2004058159A2
(en)
|
2002-12-23 |
2004-07-15 |
Dynavax Technologies Corporation |
Branched immunomodulatory compounds and methods of using the same
|
US7169892B2
(en)
|
2003-01-10 |
2007-01-30 |
Astellas Pharma Inc. |
Lipid-peptide-polymer conjugates for long blood circulation and tumor specific drug delivery systems
|
WO2004067728A2
(en)
|
2003-01-17 |
2004-08-12 |
Ptc Therapeutics |
Methods and systems for the identification of rna regulatory sequences and compounds that modulate their function
|
US9068234B2
(en)
|
2003-01-21 |
2015-06-30 |
Ptc Therapeutics, Inc. |
Methods and agents for screening for compounds capable of modulating gene expression
|
US8426194B2
(en)
|
2003-01-21 |
2013-04-23 |
Ptc Therapeutics, Inc. |
Methods and agents for screening for compounds capable of modulating VEGF expression
|
US8460864B2
(en)
|
2003-01-21 |
2013-06-11 |
Ptc Therapeutics, Inc. |
Methods for identifying compounds that modulate untranslated region-dependent gene expression and methods of using same
|
US20040147027A1
(en)
|
2003-01-28 |
2004-07-29 |
Troy Carol M. |
Complex for facilitating delivery of dsRNA into a cell and uses thereof
|
EP1592440A4
(en)
|
2003-02-10 |
2007-07-11 |
Elan Pharm Inc |
IMMUNOGLOBULIN PREPARATION AND METHOD OF PRODUCING THE SAME
|
US20040167090A1
(en)
|
2003-02-21 |
2004-08-26 |
Monahan Sean D. |
Covalent modification of RNA for in vitro and in vivo delivery
|
CA2450289A1
(en)
|
2003-03-20 |
2005-05-19 |
Imclone Systems Incorporated |
Method of producing an antibody to epidermal growth factor receptor
|
US7320961B2
(en)
|
2003-03-24 |
2008-01-22 |
Abbott Laboratories |
Method for treating a disease, disorder or adverse effect caused by an elevated serum concentration of an UGT1A1 substrate
|
JP4722035B2
(ja)
|
2003-03-25 |
2011-07-13 |
アジレント・テクノロジーズ・インク |
Dnaポリメラーゼ融合物およびその使用
|
US20040242502A1
(en)
|
2003-04-08 |
2004-12-02 |
Galenica Pharmaceuticals, Inc. |
Semi-synthetic saponin analogs with carrier and immune stimulatory activities for DNA and RNA vaccines
|
MXPA05010778A
(es)
|
2003-04-09 |
2005-12-12 |
Genentech Inc |
Terapia para enfermedad autoinmune en un paciente con una respuesta inadecuada a un inhibidor tnf-alfa.
|
EP1620140B1
(en)
|
2003-05-05 |
2013-10-09 |
Ben-Gurion University Of The Negev Research And Development Authority |
Injectable cross-linked polymeric preparations and uses thereof
|
EP2298347B1
(en)
|
2003-05-06 |
2015-09-30 |
Biogen Hemophilia Inc. |
Clotting factor chimeric proteins for treatment of a hemostatic disorder
|
TWI353991B
(en)
|
2003-05-06 |
2011-12-11 |
Syntonix Pharmaceuticals Inc |
Immunoglobulin chimeric monomer-dimer hybrids
|
US7348004B2
(en)
|
2003-05-06 |
2008-03-25 |
Syntonix Pharmaceuticals, Inc. |
Immunoglobulin chimeric monomer-dimer hybrids
|
US20040226556A1
(en)
|
2003-05-13 |
2004-11-18 |
Deem Mark E. |
Apparatus for treating asthma using neurotoxin
|
US9567591B2
(en)
|
2003-05-15 |
2017-02-14 |
Mello Biotechnology, Inc. |
Generation of human embryonic stem-like cells using intronic RNA
|
GB0313132D0
(en)
|
2003-06-06 |
2003-07-09 |
Ich Productions Ltd |
Peptide ligands
|
WO2005009346A2
(en)
|
2003-06-24 |
2005-02-03 |
Mirus Corporation |
Inhibition of gene function by delivery of polynucleotide-based gene expression inhibitors to mammalian cells in vivo
|
GB0316089D0
(en)
|
2003-07-09 |
2003-08-13 |
Xo Bioscience Ltd |
Differentiation method
|
US8592197B2
(en)
|
2003-07-11 |
2013-11-26 |
Novavax, Inc. |
Functional influenza virus-like particles (VLPs)
|
US7575572B2
(en)
|
2003-07-15 |
2009-08-18 |
Spinal Generations, Llc |
Method and device for delivering medicine to bone
|
US20050013870A1
(en)
|
2003-07-17 |
2005-01-20 |
Toby Freyman |
Decellularized extracellular matrix of conditioned body tissues and uses thereof
|
CN101124240B
(zh)
|
2003-07-18 |
2013-12-18 |
安姆根有限公司 |
肝细胞生长因子的特异性结合物
|
US7683036B2
(en)
|
2003-07-31 |
2010-03-23 |
Regulus Therapeutics Inc. |
Oligomeric compounds and compositions for use in modulation of small non-coding RNAs
|
DE10335833A1
(de)
|
2003-08-05 |
2005-03-03 |
Curevac Gmbh |
Transfektion von Blutzellen mit mRNA zur Immunstimulation und Gentherapie
|
US8668926B1
(en)
|
2003-09-15 |
2014-03-11 |
Shaker A. Mousa |
Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists, and formulations thereof
|
US7135010B2
(en)
|
2003-09-30 |
2006-11-14 |
Damage Control Surgical Technologies, Inc. |
Method and apparatus for rapid deployment chest drainage
|
BRPI0415302A
(pt)
|
2003-10-06 |
2006-12-05 |
Novartis Ag |
uso de polimorfismos genéticos que se associam a eficácia de tratamento de doença inflamatória
|
US20050130201A1
(en)
|
2003-10-14 |
2005-06-16 |
Dharmacon, Inc. |
Splint-assisted enzymatic synthesis of polyribounucleotides
|
DE10347710B4
(de)
|
2003-10-14 |
2006-03-30 |
Johannes-Gutenberg-Universität Mainz |
Rekombinante Impfstoffe und deren Verwendung
|
RS54450B1
(en)
|
2003-11-05 |
2016-06-30 |
Roche Glycart Ag |
ANTIGEN-BINDING MOLECULES WITH INCREASED BINDING AFFINITY FOR FC RECEPTOR AND EFFECTOR FUNCTION
|
WO2005047536A2
(en)
|
2003-11-13 |
2005-05-26 |
Novartis Ag |
Detection of genomic amplification and deletion in cancer
|
US20070054278A1
(en)
|
2003-11-18 |
2007-03-08 |
Applera Corporation |
Polymorphisms in nucleic acid molecules encoding human enzyme proteins, methods of detection and uses thereof
|
US7998119B2
(en)
|
2003-11-18 |
2011-08-16 |
Nano Pass Technologies Ltd. |
System and method for delivering fluid into flexible biological barrier
|
US7699852B2
(en)
|
2003-11-19 |
2010-04-20 |
Zimmer Spine, Inc. |
Fenestrated bone tap and method
|
US20050153333A1
(en)
|
2003-12-02 |
2005-07-14 |
Sooknanan Roy R. |
Selective terminal tagging of nucleic acids
|
EP1691746B1
(en)
|
2003-12-08 |
2015-05-27 |
Gel-Del Technologies, Inc. |
Mucoadhesive drug delivery devices and methods of making and using thereof
|
US7674884B2
(en)
|
2003-12-10 |
2010-03-09 |
Novimmune S.A. |
Neutralizing antibodies and methods of use thereof
|
WO2005062854A2
(en)
|
2003-12-19 |
2005-07-14 |
University Of Cincinnati |
Polyamides for nucleic acid delivery
|
SI1711528T1
(sl)
|
2003-12-23 |
2012-10-30 |
Genentech Inc |
Zdravljenje raka z novimi anti-il 13 monoklonskimi protitelesi
|
US20050143336A1
(en)
|
2003-12-30 |
2005-06-30 |
Board Of Regents, The University Of Texas System |
Methods and compositions for improved non-viral gene therapy
|
US7150726B2
(en)
|
2004-01-23 |
2006-12-19 |
Norfolk Medical |
Device for subcutaneous infusion of fluids
|
WO2005072710A2
(en)
|
2004-01-28 |
2005-08-11 |
Johns Hopkins University |
Drugs and gene carrier particles that rapidly move through mucous barriers
|
EP1716233B1
(en)
|
2004-01-30 |
2009-08-26 |
Maxygen Holdings Ltd. |
Regulated stop codon readthrough
|
US7309487B2
(en)
|
2004-02-09 |
2007-12-18 |
George Inana |
Methods and compositions for detecting and treating retinal diseases
|
CA2556027C
(en)
|
2004-02-12 |
2015-11-24 |
Morphotek, Inc. |
Monoclonal antibodies that specifically block biological activity of a tumor antigen
|
US20070265220A1
(en)
|
2004-03-15 |
2007-11-15 |
City Of Hope |
Methods and compositions for the specific inhibition of gene expression by double-stranded RNA
|
EP3269738A1
(en)
|
2004-03-24 |
2018-01-17 |
Chugai Seiyaku Kabushiki Kaisha |
Subtypes of humanized antibody against interleukin-6 receptor
|
WO2005098433A2
(en)
|
2004-04-01 |
2005-10-20 |
Novartis Ag |
Diagnostic assays for alzheimer’s disease
|
US8882717B2
(en)
|
2004-04-12 |
2014-11-11 |
Allergan, Inc. |
Multi-site injection system
|
NZ550320A
(en)
|
2004-04-15 |
2010-02-26 |
Chiasma Inc |
Compositions capable of facilitating penetration across a biological barrier
|
JP5848861B2
(ja)
|
2004-04-20 |
2016-01-27 |
ジェンマブ エー/エスGenmab A/S |
Cd20に対するヒトモノクローナル抗体
|
ES2246694B1
(es)
|
2004-04-29 |
2007-05-01 |
Instituto Cientifico Y Tecnologico De Navarra, S.A. |
Nanoparticulas pegiladas.
|
US20080119645A1
(en)
|
2004-05-05 |
2008-05-22 |
Isis Pharmaceuticals, Inc. |
Amidites and Methods of Rna Synthesis
|
WO2005112894A1
(en)
*
|
2004-05-12 |
2005-12-01 |
Baxter International Inc. |
Nucleic acid microspheres, production and delivery thereof
|
CN1980640A
(zh)
*
|
2004-05-12 |
2007-06-13 |
巴克斯特国际公司 |
核酸微球体,其制备和递送
|
US20080103053A1
(en)
|
2005-11-22 |
2008-05-01 |
Helicos Biosciences Corporation |
Methods and compositions for sequencing a nucleic acid
|
US20060020329A1
(en)
|
2004-05-26 |
2006-01-26 |
Medtronic Vascular, Inc. |
Semi-directional drug delivering stents
|
CA2568772A1
(en)
|
2004-06-01 |
2005-12-15 |
San Diego State University Foundation |
Expression system based on recombinant vesicular stomatitis virus synthesizing t7 rna polymerase
|
EP1766035B1
(en)
|
2004-06-07 |
2011-12-07 |
Protiva Biotherapeutics Inc. |
Lipid encapsulated interfering rna
|
US7745651B2
(en)
|
2004-06-07 |
2010-06-29 |
Protiva Biotherapeutics, Inc. |
Cationic lipids and methods of use
|
EP1773240B1
(en)
|
2004-06-11 |
2019-11-20 |
Trustees of the Tufts College |
Silk-based drug delivery system
|
US8338648B2
(en)
|
2004-06-12 |
2012-12-25 |
Signum Biosciences, Inc. |
Topical compositions and methods for epithelial-related conditions
|
WO2006046978A2
(en)
|
2004-06-28 |
2006-05-04 |
Argos Therapeutics, Inc. |
Cationic peptide-mediated transformation
|
KR101100059B1
(ko)
|
2004-06-30 |
2011-12-29 |
넥타르 테라퓨틱스 |
중합체인자 ix 부분의 접합체
|
JP2008505685A
(ja)
|
2004-07-06 |
2008-02-28 |
トランスファーマ メディカル リミテッド |
経皮免疫処置用送達システム
|
DE102004035227A1
(de)
*
|
2004-07-21 |
2006-02-16 |
Curevac Gmbh |
mRNA-Gemisch zur Vakzinierung gegen Tumorerkrankungen
|
US7579451B2
(en)
|
2004-07-21 |
2009-08-25 |
Alnylam Pharmaceuticals, Inc. |
Oligonucleotides comprising a modified or non-natural nucleobase
|
US7603349B1
(en)
|
2004-07-29 |
2009-10-13 |
Yahoo! Inc. |
User interfaces for search systems using in-line contextual queries
|
GB0417487D0
(en)
|
2004-08-05 |
2004-09-08 |
Novartis Ag |
Organic compound
|
SE0402025D0
(sv)
|
2004-08-13 |
2004-08-13 |
Active Biotech Ab |
Treatment of hyperproliferative disease with superantigens in combination with another anticancer agent
|
US7291208B2
(en)
|
2004-08-13 |
2007-11-06 |
Gore Enterprise Holdings, Inc. |
Grooved active and passive adsorbent filters
|
CA2478458A1
(en)
|
2004-08-20 |
2006-02-20 |
Michael Panzara |
Treatment of pediatric multiple sclerosis
|
HUE024999T2
(en)
|
2004-08-26 |
2016-02-29 |
Engeneic Molecular Delivery Pty Ltd |
Introducing functional nucleic acids into mammalian cells with bacterial intact minicells
|
DE102004042546A1
(de)
|
2004-09-02 |
2006-03-09 |
Curevac Gmbh |
Kombinationstherapie zur Immunstimulation
|
US7501486B2
(en)
|
2004-09-07 |
2009-03-10 |
Burnham Institute For Medical Research |
Peptides that selectively home to heart vasculature and related conjugates and methods
|
US8396548B2
(en)
|
2008-11-14 |
2013-03-12 |
Vessix Vascular, Inc. |
Selective drug delivery in a lumen
|
US8663599B1
(en)
|
2004-10-05 |
2014-03-04 |
Gp Medical, Inc. |
Pharmaceutical composition of nanoparticles
|
EP1811018A4
(en)
|
2004-10-12 |
2007-11-28 |
Tissue Targeting Japan Inc |
PROGENITOR FOR BRAIN DISPOSAL FROM BONE MARROW
|
WO2006044682A1
(en)
|
2004-10-13 |
2006-04-27 |
Ptc Therapeutics, Inc. |
Compounds for nonsense suppression, and methods for their use
|
US8057821B2
(en)
|
2004-11-03 |
2011-11-15 |
Egen, Inc. |
Biodegradable cross-linked cationic multi-block copolymers for gene delivery and methods of making thereof
|
US20080261905A1
(en)
|
2004-11-08 |
2008-10-23 |
K.U. Leuven Research And Development |
Modified Nucleosides for Rna Interference
|
CA2587216C
(en)
|
2004-11-18 |
2014-11-18 |
Nanopass Technologies Ltd. |
System and method for delivering fluid into flexible biological barrier
|
US8946444B2
(en)
|
2004-11-23 |
2015-02-03 |
Ptc Therapeutics, Inc. |
Tetrahydrocarbazoles as active agents for inhibiting VEGF production by translational control
|
US7964571B2
(en)
|
2004-12-09 |
2011-06-21 |
Egen, Inc. |
Combination of immuno gene therapy and chemotherapy for treatment of cancer and hyperproliferative diseases
|
US8354476B2
(en)
|
2004-12-10 |
2013-01-15 |
Kala Pharmaceuticals, Inc. |
Functionalized poly(ether-anhydride) block copolymers
|
US9068969B2
(en)
|
2004-12-28 |
2015-06-30 |
Ptc Therapeutics, Inc. |
Cell based methods and systems for the identification of RNA regulatory sequences and compounds that modulate their functions
|
US8187570B1
(en)
|
2005-01-04 |
2012-05-29 |
Gp Medical, Inc. |
Nanoparticles for protein drug delivery
|
US8192718B1
(en)
|
2005-01-04 |
2012-06-05 |
Gp Medical, Inc. |
Pharmaceutical composition of nanoparticles
|
US8535702B2
(en)
|
2005-02-01 |
2013-09-17 |
Boston Scientific Scimed, Inc. |
Medical devices having porous polymeric regions for controlled drug delivery and regulated biocompatibility
|
US7404969B2
(en)
|
2005-02-14 |
2008-07-29 |
Sirna Therapeutics, Inc. |
Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules
|
EP1922300A2
(en)
|
2005-02-14 |
2008-05-21 |
Sirna Therapeutics Inc. |
Cationic lipids and formulated molecular compositions containing them
|
US20060263338A1
(en)
|
2005-03-04 |
2006-11-23 |
Jacoby Douglas B |
Catheter-based delivery of Skeletal Myoblasts to the Myocardium of Damaged Hearts
|
US20100221186A1
(en)
|
2005-03-11 |
2010-09-02 |
Hueseyin Firat |
Biomarkers for cardiovascular side-effects induced by cox-2 inhibitory compounds
|
JP4793806B2
(ja)
|
2005-03-22 |
2011-10-12 |
Tti・エルビュー株式会社 |
イオントフォレーシス装置
|
US8415325B2
(en)
|
2005-03-31 |
2013-04-09 |
University Of Delaware |
Cell-mediated delivery and targeted erosion of noncovalently crosslinked hydrogels
|
AU2006231452B2
(en)
|
2005-04-01 |
2011-05-26 |
Intezyne Technologies, Inc. |
Polymeric micelles for drug delivery
|
CA2604844A1
(en)
|
2005-04-07 |
2006-10-19 |
Novartis Vaccines And Diagnostics, Inc. |
Cancer-related genes
|
JP2008535857A
(ja)
|
2005-04-07 |
2008-09-04 |
ノバルティス ヴァクシンズ アンド ダイアグノスティクス インコーポレイテッド |
癌の診断、検出および処置におけるcacna1e
|
WO2006110776A2
(en)
|
2005-04-12 |
2006-10-19 |
Nektar Therapeutics Al, Corporation |
Polyethylene glycol cojugates of antimicrobial agents
|
WO2006116458A2
(en)
|
2005-04-26 |
2006-11-02 |
Coley Pharmaceutical Gmbh |
Modified oligoribonucleotide analogs with enhances immunostimulatory activity
|
US7850656B2
(en)
|
2005-04-29 |
2010-12-14 |
Warsaw Orthopedic, Inc. |
Devices and methods for delivering medical agents
|
EP2418278A3
(en)
|
2005-05-09 |
2012-07-04 |
Ono Pharmaceutical Co., Ltd. |
Human monoclonal antibodies to programmed death 1(PD-1) and methods for treating cancer using anti-PD-1 antibodies alone or in combination with other immunotherapeutics
|
US8246995B2
(en)
|
2005-05-10 |
2012-08-21 |
The Board Of Trustees Of The Leland Stanford Junior University |
Hydrophobic nanotubes and nanoparticles as transporters for the delivery of drugs into cells
|
US20070072175A1
(en)
|
2005-05-13 |
2007-03-29 |
Biogen Idec Ma Inc. |
Nucleotide array containing polynucleotide probes complementary to, or fragments of, cynomolgus monkey genes and the use thereof
|
US20060265771A1
(en)
|
2005-05-17 |
2006-11-23 |
Lewis David L |
Monitoring microrna expression and function
|
DE102005023170A1
(de)
|
2005-05-19 |
2006-11-23 |
Curevac Gmbh |
Optimierte Formulierung für mRNA
|
JP2008541770A
(ja)
|
2005-06-03 |
2008-11-27 |
ジェネンテック・インコーポレーテッド |
改変したフコシル化レベルを有する抗体の産生方法
|
US7550264B2
(en)
|
2005-06-10 |
2009-06-23 |
Datascope Investment Corporation |
Methods and kits for sense RNA synthesis
|
US7691086B2
(en)
|
2005-06-14 |
2010-04-06 |
Tengiz Tkebuchava |
Catheter for introduction of medications to the tissues of a heart or other organ
|
CN101242858B
(zh)
|
2005-06-16 |
2012-12-19 |
尼克塔治疗公司 |
具有可降解键的轭合物以及用于制备这种轭合物的聚合物试剂
|
US20110182805A1
(en)
|
2005-06-17 |
2011-07-28 |
Desimone Joseph M |
Nanoparticle fabrication methods, systems, and materials
|
US8202835B2
(en)
|
2005-06-17 |
2012-06-19 |
Yitzchak Hillman |
Disease treatment via antimicrobial peptides or their inhibitors
|
RU2008103346A
(ru)
|
2005-06-30 |
2009-08-10 |
Аркемикс Корп. (Us) |
Материалы и способы для получения полностью 2-модифицированных транскриптов нуклеиновых кислот
|
US8101385B2
(en)
|
2005-06-30 |
2012-01-24 |
Archemix Corp. |
Materials and methods for the generation of transcripts comprising modified nucleotides
|
US20080220471A1
(en)
|
2005-07-27 |
2008-09-11 |
Genentech, Inc. |
Vectors and Methods Using Same
|
US9012219B2
(en)
|
2005-08-23 |
2015-04-21 |
The Trustees Of The University Of Pennsylvania |
RNA preparations comprising purified modified RNA for reprogramming cells
|
PL2578685T3
(pl)
*
|
2005-08-23 |
2020-01-31 |
The Trustees Of The University Of Pennsylvania |
Rna zawierający zmodyfikowane nukleozydy i sposoby jego zastosowania
|
US20070048741A1
(en)
|
2005-08-24 |
2007-03-01 |
Getts Robert C |
Methods and kits for sense RNA synthesis
|
ATE499112T1
(de)
|
2005-09-01 |
2011-03-15 |
Celgene Corp |
Immunologische verwendungen von immunmodulatorischen verbindungen für einen impfstoff und therapie gegen infektionskrankheiten
|
WO2007026249A2
(en)
|
2005-09-01 |
2007-03-08 |
Novartis Vaccines And Diagnostics Gmbh & Co Kg |
Multiple vaccination including serogroup c meningococcus
|
WO2007029361A1
(ja)
*
|
2005-09-02 |
2007-03-15 |
Takeda Pharmaceutical Company Limited |
短鎖デオキシリボ核酸又は短鎖リボ核酸含有徐放性マイクロスフェア及びその製造法
|
US8420605B2
(en)
|
2005-09-07 |
2013-04-16 |
The University Of Strathclyde |
Hydrogel compositions
|
US20120021042A1
(en)
|
2005-09-15 |
2012-01-26 |
Steffen Panzner |
Efficient Method For Loading Amphoteric Liposomes With Nucleic Acid Active Substances
|
US20070185432A1
(en)
|
2005-09-19 |
2007-08-09 |
Transport Pharmaceuticals, Inc. |
Electrokinetic system and method for delivering methotrexate
|
DE102005046490A1
(de)
|
2005-09-28 |
2007-03-29 |
Johannes-Gutenberg-Universität Mainz |
Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen
|
US20070087437A1
(en)
|
2005-10-14 |
2007-04-19 |
Jifan Hu |
Methods for rejuvenating cells in vitro and in vivo
|
US8012096B2
(en)
|
2005-10-17 |
2011-09-06 |
Cardiogenesis Corporation |
Surgical device and method for performing combination revascularization and therapeutic substance delivery to tissue
|
AU2006310339B2
(en)
|
2005-11-04 |
2013-01-10 |
Novartis Ag |
Influenza vaccines including combinations of particulate adjuvants and immunopotentiators
|
US20070105124A1
(en)
|
2005-11-08 |
2007-05-10 |
Getts Robert C |
Methods and kits for nucleic acid amplification
|
US20090170090A1
(en)
|
2005-11-18 |
2009-07-02 |
Bioline Limited |
Method for Enhancing Enzymatic DNA Polymerase Reactions
|
JP5525729B2
(ja)
|
2005-11-28 |
2014-06-18 |
ゲンマブ エー/エス |
組換え一価抗体およびその作製方法
|
AU2005338632B2
(en)
|
2005-11-30 |
2010-05-20 |
Epicentre Technologies Corporation |
Selective terminal tagging of nucleic acids
|
TWI389709B
(zh)
|
2005-12-01 |
2013-03-21 |
Novartis Ag |
經皮治療系統
|
US9393215B2
(en)
|
2005-12-02 |
2016-07-19 |
Novartis Ag |
Nanoparticles for use in immunogenic compositions
|
US8603457B2
(en)
|
2005-12-02 |
2013-12-10 |
University Of Rochester |
Nonsense suppression and genetic codon alteration by targeted modification
|
US7579318B2
(en)
|
2005-12-06 |
2009-08-25 |
Centre De La Recherche De La Scientifique |
Cell penetrating peptides for intracellular delivery of molecules
|
WO2007069090A2
(en)
|
2005-12-06 |
2007-06-21 |
Centre National De La Recherche Scientifique |
Cell penetrating peptides for intracellular delivery of molecules
|
AU2006321602B2
(en)
|
2005-12-08 |
2012-03-08 |
Novartis Ag |
Effects of inhibitors of FGFR3 on gene transcription
|
CN101864392B
(zh)
|
2005-12-13 |
2016-03-23 |
国立大学法人京都大学 |
核重新编程因子
|
EP1968643A2
(en)
|
2005-12-16 |
2008-09-17 |
Diatos |
Cell penetrating peptide conjugates for delivering of nucleic acids into a cell
|
CA2636817C
(en)
|
2006-01-12 |
2015-11-03 |
Massachusetts Institute Of Technology |
Biodegradable elastomers
|
KR101421745B1
(ko)
|
2006-01-13 |
2014-07-22 |
더 트러스티스 오브 더 유니버시티 오브 펜실바니아 |
코돈 최적화된 il―15를 사용하는 백신 및 면역치료제, 및 그의 사용 방법
|
AU2007211080B9
(en)
|
2006-01-27 |
2012-05-03 |
Isis Pharmaceuticals, Inc. |
6-modified bicyclic nucleic acid analogs
|
CN101420977B
(zh)
|
2006-01-27 |
2016-08-10 |
比奥根Ma公司 |
Nogo受体拮抗剂
|
US20070178103A1
(en)
|
2006-01-30 |
2007-08-02 |
Fey Georg H |
CD19-specific immunotoxin and treatment method
|
US8946155B2
(en)
|
2006-02-03 |
2015-02-03 |
Opko Biologics Ltd. |
Long-acting polypeptides and methods of producing and administering same
|
US9458444B2
(en)
|
2006-02-03 |
2016-10-04 |
Opko Biologics Ltd. |
Long-acting coagulation factors and methods of producing same
|
US8476234B2
(en)
|
2006-02-03 |
2013-07-02 |
Prolor Biotech Inc. |
Long-acting coagulation factors and methods of producing same
|
DE102006007433A1
(de)
|
2006-02-17 |
2007-08-23 |
Curevac Gmbh |
Adjuvanz in Form einer Lipid-modifizierten Nukleinsäure
|
KR100859972B1
(ko)
|
2006-02-20 |
2008-09-25 |
이화여자대학교 산학협력단 |
막투과 단백질 도메인 펩타이드
|
US8309680B2
(en)
|
2006-02-21 |
2012-11-13 |
Nektar Therapeutics |
Segmented degradable polymers and conjugates made therefrom
|
US20080038278A1
(en)
|
2006-02-24 |
2008-02-14 |
Jingsong Cao |
GPAT3 encodes a mammalian, microsomal acyl-coa:glycerol 3- phosphate acyltransferase
|
AU2007221154A1
(en)
|
2006-02-24 |
2007-09-07 |
Novartis Ag |
Microparticles containing biodegradable polymer and cationic polysaccharide for use in immunogenic compositions
|
JP2009528359A
(ja)
|
2006-02-28 |
2009-08-06 |
エラン ファーマシューティカルズ,インコーポレイテッド |
ナタリズマブを用いて炎症性疾患および自己免疫性疾患を治療する方法
|
US7910152B2
(en)
|
2006-02-28 |
2011-03-22 |
Advanced Cardiovascular Systems, Inc. |
Poly(ester amide)-based drug delivery systems with controlled release rate and morphology
|
GB0605217D0
(en)
|
2006-03-15 |
2006-04-26 |
Novartis Ag |
Method and compositions for assessing acute rejection
|
US8231907B2
(en)
|
2006-03-21 |
2012-07-31 |
Morehouse School Of Medicine |
Nanoparticles for delivery of active agents
|
WO2008105773A2
(en)
|
2006-03-31 |
2008-09-04 |
Massachusetts Institute Of Technology |
System for targeted delivery of therapeutic agents
|
US8257685B2
(en)
|
2006-04-04 |
2012-09-04 |
Stc.Unm |
Swellable particles for drug delivery
|
WO2007120863A2
(en)
|
2006-04-14 |
2007-10-25 |
Epicentre Technologies |
Kits and methods for generating 5' capped rna
|
EP1852127A1
(en)
|
2006-05-02 |
2007-11-07 |
Charité - Universitätsmedizin Berlin |
Use of a B-cell-depleting antibody for treatment of polyoma virus infections
|
CN101573141B
(zh)
|
2006-05-15 |
2016-05-04 |
麻省理工学院 |
用于功能性颗粒的聚合物
|
JP2009537605A
(ja)
|
2006-05-24 |
2009-10-29 |
メルク セローノ ソシエテ アノニム |
多発性硬化症を治療するためのクラドリビン・レジメン
|
CN104356230A
(zh)
|
2006-06-02 |
2015-02-18 |
哈佛大学校长及研究员协会 |
蛋白质表面重建
|
US9506056B2
(en)
|
2006-06-08 |
2016-11-29 |
Northwestern University |
Nucleic acid functionalized nanoparticles for therapeutic applications
|
EP2046383B1
(en)
|
2006-07-04 |
2014-11-19 |
Genmab A/S |
Cd20 binding molecules for the treatment of copd
|
EP2397123A1
(en)
*
|
2006-07-07 |
2011-12-21 |
Aarhus Universitet |
Nanoparticles for nucleic acid delivery
|
TWI441835B
(zh)
|
2006-07-12 |
2014-06-21 |
Novartis Ag |
新穎聚合物
|
JP2009544287A
(ja)
|
2006-07-20 |
2009-12-17 |
ノバルティス アーゲー |
癌を処置、診断、または検出するためのamigo−2インヒビター
|
JP5571380B2
(ja)
|
2006-07-24 |
2014-08-13 |
ルミナス バイオサイエンシズ,インコーポレイテッド |
オストワルド熟成を減少させた水不溶性の医薬品物質の固体ナノ粒子処方物
|
CA2659301A1
(en)
|
2006-07-28 |
2008-02-07 |
Applera Corporation |
Dinucleotide mrna cap analogs
|
AU2007280690C1
(en)
|
2006-07-31 |
2012-08-23 |
Curevac Gmbh |
Nucleic acid of formula (I): GIXmGn, or (II): CIXmCn, in particular as an immune-stimulating agent/adjuvant
|
DE102006035618A1
(de)
|
2006-07-31 |
2008-02-07 |
Curevac Gmbh |
Nukleinsäure der Formel (I): GlXmGn, insbesondere als immunstimulierendes Adjuvanz
|
RU2009108289A
(ru)
|
2006-08-07 |
2010-09-20 |
Джензим Корпорейшн (Us) |
Комбинированная терапия
|
AU2007286059A1
(en)
|
2006-08-18 |
2008-02-21 |
Mdrna, Inc. |
Dicer substrate RNA peptide conjugates and methods for RNA therapeutics
|
US8658211B2
(en)
|
2006-08-18 |
2014-02-25 |
Arrowhead Madison Inc. |
Polyconjugates for in vivo delivery of polynucleotides
|
AU2007292221B2
(en)
|
2006-09-06 |
2013-08-29 |
The Regents Of The University Of California |
Selectively targeted antimicrobial peptides and the use thereof
|
KR101485197B1
(ko)
|
2006-09-07 |
2015-01-23 |
크루셀 홀란드 비.브이. |
인플루엔자 바이러스 h5n1을 중화시킬 수 있는 인간 결합분자 및 그것의 용도
|
US20080140061A1
(en)
|
2006-09-08 |
2008-06-12 |
Arbel Medical Ltd. |
Method And Device For Combined Treatment
|
ES2360538T3
(es)
|
2006-09-08 |
2011-06-06 |
Johns Hopkins University |
Composiciones para aumentar el transporte a través de moco.
|
US8454948B2
(en)
|
2006-09-14 |
2013-06-04 |
Medgenics Medical Israel Ltd. |
Long lasting drug formulations
|
GB0619182D0
(en)
|
2006-09-29 |
2006-11-08 |
Leuven K U Res & Dev |
Oligonucleotide arrays
|
KR101129509B1
(ko)
|
2006-10-03 |
2012-04-13 |
알닐람 파마슈티칼스 인코포레이티드 |
지질 함유 조성물
|
CN101583379B
(zh)
|
2006-10-05 |
2013-04-03 |
约翰斯霍普金斯大学 |
使用优良聚合物纳米粒子的水溶性差药物的水可分散性口服,肠胃外和局部制剂
|
DE102006051516A1
(de)
|
2006-10-31 |
2008-05-08 |
Curevac Gmbh |
(Basen-)modifizierte RNA zur Expressionssteigerung eines Proteins
|
US8414927B2
(en)
|
2006-11-03 |
2013-04-09 |
Boston Scientific Scimed, Inc. |
Cross-linked polymer particles
|
US7999087B2
(en)
|
2006-11-15 |
2011-08-16 |
Agilent Technologies, Inc. |
2′-silyl containing thiocarbonate protecting groups for RNA synthesis
|
US8242258B2
(en)
|
2006-12-03 |
2012-08-14 |
Agilent Technologies, Inc. |
Protecting groups for RNA synthesis
|
US8399007B2
(en)
|
2006-12-05 |
2013-03-19 |
Landec Corporation |
Method for formulating a controlled-release pharmaceutical formulation
|
CN101553252A
(zh)
|
2006-12-06 |
2009-10-07 |
诺华有限公司 |
包含来自于四株流感病毒的抗原的疫苗
|
US9034348B2
(en)
|
2006-12-11 |
2015-05-19 |
Chi2Gel Ltd. |
Injectable chitosan mixtures forming hydrogels
|
KR102223231B1
(ko)
|
2006-12-18 |
2021-03-08 |
악셀레론 파마 인코포레이티드 |
액티빈-actrii 길항물질과 적혈구 수준을 증가시키기 위한 이의 용도
|
EP2104739B1
(en)
|
2006-12-21 |
2013-06-19 |
Novozymes Inc. |
Modified messenger rna stabilizing sequences for expressing genes in bacterial cells
|
CA2671925A1
(en)
|
2006-12-21 |
2008-07-10 |
Stryker Corporation |
Sustained-release formulations comprising crystals, macromolecular gels, and particulate suspensions of biologic agents
|
WO2008078180A2
(en)
|
2006-12-22 |
2008-07-03 |
Archemix Corp. |
Materials and methods for the generation of transcripts comprising modified nucleotides
|
DE102006061015A1
(de)
|
2006-12-22 |
2008-06-26 |
Curevac Gmbh |
Verfahren zur Reinigung von RNA im präparativen Maßstab mittels HPLC
|
US8057426B2
(en)
|
2007-01-03 |
2011-11-15 |
Medtronic Vascular, Inc. |
Devices and methods for injection of multiple-component therapies
|
US8338166B2
(en)
|
2007-01-04 |
2012-12-25 |
Lawrence Livermore National Security, Llc |
Sorting, amplification, detection, and identification of nucleic acid subsequences in a complex mixture
|
DE102007001370A1
(de)
|
2007-01-09 |
2008-07-10 |
Curevac Gmbh |
RNA-kodierte Antikörper
|
WO2008091799A2
(en)
|
2007-01-22 |
2008-07-31 |
The Trustees Of Columbia University In The City Of New York |
Cell-based methods for identifying inhibitors of parkinson's disease-associated lrrk2 mutants
|
CN103755789B
(zh)
|
2007-01-30 |
2016-12-07 |
埃皮瓦克斯公司 |
调节性t细胞表位、组合物及其用途
|
TWI782836B
(zh)
|
2007-02-02 |
2022-11-01 |
美商艾瑟勒朗法瑪公司 |
衍生自ActRIIB的變體與其用途
|
WO2008097926A2
(en)
|
2007-02-02 |
2008-08-14 |
Yale University |
Transient transfection with rna
|
WO2008096370A2
(en)
|
2007-02-05 |
2008-08-14 |
Natco Pharma Limited |
An efficient and novel purification method of recombinant hg-csf
|
US8333799B2
(en)
|
2007-02-12 |
2012-12-18 |
C. R. Bard, Inc. |
Highly flexible stent and method of manufacture
|
WO2008103276A2
(en)
|
2007-02-16 |
2008-08-28 |
Merck & Co., Inc. |
Compositions and methods for potentiated activity of biologicaly active molecules
|
US8242087B2
(en)
|
2007-02-27 |
2012-08-14 |
K.U.Leuven Research & Development |
Phosphate modified nucleosides useful as substrates for polymerases and as antiviral agents
|
EP2522729A1
(en)
|
2007-03-02 |
2012-11-14 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
Improvement of protein production
|
EP1964922A1
(en)
|
2007-03-02 |
2008-09-03 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
Improvement of protein production
|
US8029496B2
(en)
|
2007-03-05 |
2011-10-04 |
Ebrahim Versi |
Method and device for delivering drug to the trigone of the bladder
|
JP5249248B2
(ja)
|
2007-03-05 |
2013-07-31 |
ワシントン ユニバーシティー |
膜組み込みペプチドのためのナノ粒子輸送システム
|
WO2008115504A2
(en)
|
2007-03-20 |
2008-09-25 |
Millennium Pharmaceuticals, Inc. |
Nucleic acids encoding humanized immunoglobulin that binds a4b7 integrin
|
SI2152358T1
(sl)
|
2007-04-27 |
2011-08-31 |
Echo Therapeutics Inc |
Naprava za prodiranje skozi koĺ˝o za analizno merjenje ali za transdermalni prenos zdravil
|
DK2152290T3
(da)
|
2007-04-30 |
2014-08-18 |
Glaxosmithkline Llc |
Fremgangsmåder til indgivelse af anti-il-5-antistoffer
|
US8703204B2
(en)
|
2007-05-03 |
2014-04-22 |
Bend Research, Inc. |
Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and anon-ionizable polymer
|
US7682789B2
(en)
*
|
2007-05-04 |
2010-03-23 |
Ventana Medical Systems, Inc. |
Method for quantifying biomolecules conjugated to a nanoparticle
|
CA2686735A1
(en)
|
2007-05-04 |
2008-11-13 |
Mdrna, Inc. |
Amino acid lipids and uses thereof
|
US8728491B2
(en)
|
2007-05-07 |
2014-05-20 |
Alba Therapeutics Corporation |
Transcutaneous delivery of therapeutic agents
|
JP5296328B2
(ja)
|
2007-05-09 |
2013-09-25 |
独立行政法人理化学研究所 |
1本鎖環状rnaおよびその製造方法
|
DK2476689T3
(en)
|
2007-05-10 |
2016-01-18 |
Agilent Technologies Inc |
Thiocarbonbeskyttende groups for RNA synthesis
|
RU2519227C2
(ru)
|
2007-05-14 |
2014-06-10 |
Медиммун, Ллк |
Способы снижения числа эозинофилов
|
WO2008144365A2
(en)
|
2007-05-17 |
2008-11-27 |
Novartis Ag |
Method for making dry powder compositions containing ds-rna based on supercritical fluid technology
|
BRPI0812384A2
(pt)
|
2007-05-22 |
2014-12-02 |
Novartis Ag |
Métodos de tratamento, diagnóstico e detecção de distúrbios associados a fgf21
|
EP2164951A2
(en)
|
2007-05-30 |
2010-03-24 |
The General Hospital Corporation |
Methods of generating pluripotent cells from somatic cells
|
SI2167523T1
(sl)
|
2007-06-19 |
2014-09-30 |
Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College |
Sinteza in uporaba anti-reverznih fosforotioatnih analogov kape obveščevalne RNA
|
US8039214B2
(en)
|
2007-06-29 |
2011-10-18 |
Cellscript, Inc. |
Synthesis of tagged nucleic acids
|
WO2009015071A1
(en)
|
2007-07-23 |
2009-01-29 |
Dharmacon, Inc. |
Screening of micro-rna cluster inhibitor pools
|
US9144546B2
(en)
|
2007-08-06 |
2015-09-29 |
Clsn Laboratories, Inc. |
Nucleic acid-lipopolymer compositions
|
US20090042825A1
(en)
|
2007-08-06 |
2009-02-12 |
Majed Matar |
Composition, method of preparation & application of concentrated formulations of condensed nucleic acids with a cationic lipopolymer
|
SG183726A1
(en)
|
2007-08-14 |
2012-09-27 |
Hutchinson Fred Cancer Res |
Needle array assembly and method for delivering therapeutic agents
|
WO2009023770A1
(en)
|
2007-08-15 |
2009-02-19 |
Avellanet Francisco J |
Biologically engineered stent
|
MX2010002113A
(es)
|
2007-08-23 |
2010-03-26 |
Novartis Ag |
Metodos para detectar oligonucleotidos.
|
WO2009030254A1
(en)
|
2007-09-04 |
2009-03-12 |
Curevac Gmbh |
Complexes of rna and cationic peptides for transfection and for immunostimulation
|
CA2697482C
(en)
|
2007-09-05 |
2016-05-31 |
F. Hoffmann-La Roche Ag |
Combination therapy with type i and type ii anti-cd20 antibodies
|
US8506928B2
(en)
|
2007-09-07 |
2013-08-13 |
The Regents Of The University Of California |
Methods and compounds for targeting tissues
|
WO2009039198A2
(en)
|
2007-09-17 |
2009-03-26 |
The Trustees Of The University Of Pennsylvania |
Generation of hyperstable mrnas
|
CA2700536A1
(en)
|
2007-09-26 |
2009-04-02 |
Oregon Health & Science University |
Cyclic undecapeptides and derivatives as multiple sclerosis therapies
|
EP3156414B1
(en)
|
2007-09-26 |
2019-12-04 |
Intrexon Corporation |
Synthetic 5'utrs, expression vectors, and methods for increasing transgene expression
|
EP2042193A1
(en)
|
2007-09-28 |
2009-04-01 |
Biomay AG |
RNA Vaccines
|
ES2647538T3
(es)
|
2007-09-28 |
2017-12-22 |
Pfizer Inc. |
Direccionamiento a células de cáncer usando nanopartículas
|
US8470560B2
(en)
|
2007-10-03 |
2013-06-25 |
The United States Of America As Represented By The Secretary Of The Army |
CR-2 binding peptide P28 as molecular adjuvant for DNA vaccines
|
WO2009046739A1
(en)
|
2007-10-09 |
2009-04-16 |
Curevac Gmbh |
Composition for treating prostate cancer (pca)
|
WO2009046738A1
(en)
|
2007-10-09 |
2009-04-16 |
Curevac Gmbh |
Composition for treating lung cancer, particularly of non-small lung cancers (nsclc)
|
BRPI0817664A2
(pt)
|
2007-10-12 |
2015-03-24 |
Massachusetts Inst Technology |
Nanopartículas, método para preparar nanopartículas e método para tratar terapeuticamente ou profilaticamente um indivíduo
|
US20090098118A1
(en)
|
2007-10-15 |
2009-04-16 |
Thomas Friess |
Combination therapy of a type ii anti-cd20 antibody with an anti-bcl-2 active agent
|
CN101903018B
(zh)
*
|
2007-10-17 |
2012-09-05 |
韩国科学技术院 |
用于递送核酸基因的ldl样阳离子纳米微粒、其制备方法以及使用其递送核酸基因的方法
|
WO2009052830A1
(en)
|
2007-10-22 |
2009-04-30 |
Genmab A/S |
Novel antibody therapies
|
AU2008319183B2
(en)
|
2007-11-01 |
2014-09-04 |
University Of Rochester |
Recombinant factor VIII having increased stability
|
WO2009062054A1
(en)
|
2007-11-09 |
2009-05-14 |
Novartis Ag |
Uses of anti-cd40 antibodies
|
US8470771B2
(en)
|
2007-11-14 |
2013-06-25 |
Institute Of Microbiology, Chinese Academy Of Sciences |
Method and medicament for inhibiting the infection of influenza virus
|
US20090137945A1
(en)
|
2007-11-28 |
2009-05-28 |
Claire Marquez |
Electro Collagen Induction Therapy Device
|
CN101932608A
(zh)
|
2007-11-30 |
2010-12-29 |
葛兰素集团有限公司 |
抗原结合构建体
|
EP2617828B1
(en)
*
|
2007-12-10 |
2014-09-24 |
Alnylam Pharmaceuticals Inc. |
Compositions and methods for inhibiting expression of factor VII gene
|
CA2904904A1
(en)
|
2007-12-11 |
2009-06-18 |
The Scripps Research Institute |
Compositions and methods related to mrna translational enhancer elements
|
EP2229459B1
(en)
|
2007-12-13 |
2014-08-27 |
Alnylam Pharmaceuticals, Inc. |
Methods and compositions for prevention or treatment of RSV infection
|
EP2072618A1
(en)
|
2007-12-14 |
2009-06-24 |
Johannes Gutenberg-Universität Mainz |
Use of RNA for reprogramming somatic cells
|
AU2008342956A1
(en)
|
2007-12-21 |
2009-07-09 |
Genentech, Inc. |
Therapy of rituximab-refractory rheumatoid arthritis patients
|
WO2009093703A1
(ja)
|
2008-01-23 |
2009-07-30 |
Ajinomoto Co., Inc. |
L-アミノ酸の製造法
|
JPWO2009093384A1
(ja)
|
2008-01-24 |
2011-05-26 |
独立行政法人産業技術総合研究所 |
ポリヌクレオチド及びポリヌクレオチド類似体並びにこれらを用いた遺伝子発現制御方法
|
EP2548960B1
(en)
|
2008-01-31 |
2018-01-31 |
CureVac AG |
Nucleic acids comprising formula (nugixmgnv)a and derivatives thereof as an immunostimulating agents/adjuvant
|
EP2250252A2
(en)
|
2008-02-11 |
2010-11-17 |
Cambridge Enterprise Limited |
Improved reprogramming of mammalian cells, and the cells obtained
|
DK2240155T3
(da)
|
2008-02-13 |
2012-09-17 |
Intarcia Therapeutics Inc |
Indretninger, formuleringer og fremgangsmåder til levering af flere gavnlige midler
|
DE102008009920A1
(de)
|
2008-02-15 |
2009-08-20 |
Aj Innuscreen Gmbh |
Mobiles Gerät für die Nukleinsäureisolierung
|
US8506966B2
(en)
|
2008-02-22 |
2013-08-13 |
Novartis Ag |
Adjuvanted influenza vaccines for pediatric use
|
US20120027813A1
(en)
|
2008-02-22 |
2012-02-02 |
Novartis Vaccines And Diagnostics Srl |
Adjuvanted influenza vaccines for pediatric use
|
WO2009108891A2
(en)
|
2008-02-29 |
2009-09-03 |
Egen, Inc. |
Modified poloxamers for gene expression and associated methods
|
CA2716919C
(en)
|
2008-03-14 |
2015-01-20 |
Biocon Limited |
An anti-cd6 monoclonal antibody and use thereof
|
US20100004315A1
(en)
|
2008-03-14 |
2010-01-07 |
Gregory Slobodkin |
Biodegradable Cross-Linked Branched Poly(Alkylene Imines)
|
WO2009120927A2
(en)
|
2008-03-28 |
2009-10-01 |
Smithkline Beecham Corporation |
Methods of treatment
|
PT2279254T
(pt)
|
2008-04-15 |
2017-09-04 |
Protiva Biotherapeutics Inc |
Novas formulações lipídicas para entrega de ácido nucleico
|
WO2009127230A1
(en)
*
|
2008-04-16 |
2009-10-22 |
Curevac Gmbh |
MODIFIED (m)RNA FOR SUPPRESSING OR AVOIDING AN IMMUNOSTIMULATORY RESPONSE AND IMMUNOSUPPRESSIVE COMPOSITION
|
US8323686B2
(en)
|
2008-04-25 |
2012-12-04 |
Northwestern University |
Nanostructures suitable for sequestering cholesterol and other molecules
|
WO2009134808A2
(en)
|
2008-04-28 |
2009-11-05 |
President And Fellows Of Harvard College |
Supercharged proteins for cell penetration
|
US8715689B2
(en)
|
2008-04-30 |
2014-05-06 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention |
Chimeric west nile/dengue viruses
|
US9394538B2
(en)
|
2008-05-07 |
2016-07-19 |
Shi-Lung Lin |
Development of universal cancer drugs and vaccines
|
US8486278B2
(en)
|
2008-05-08 |
2013-07-16 |
Minipumps, Llc |
Drug-delivery pumps and methods of manufacture
|
US8697098B2
(en)
|
2011-02-25 |
2014-04-15 |
South Dakota State University |
Polymer conjugated protein micelles
|
CA2724105C
(en)
|
2008-05-13 |
2017-09-05 |
University Of Washington |
Diblock copolymers and polynucleotide complexes thereof for delivery into cells
|
EP2297323A1
(en)
|
2008-05-21 |
2011-03-23 |
Hartmann, Gunther |
5' triphosphate oligonucleotide with blunt end and uses thereof
|
ES2872377T3
(es)
|
2008-05-26 |
2021-11-02 |
Univ Zuerich |
Nanopartículas de protamina/ARN para inmunoestimulación
|
FR2931824B1
(fr)
|
2008-05-29 |
2014-11-28 |
Centre Nat Rech Scient |
Procede de synthese d'arn par voie chimique.
|
ATE548381T1
(de)
|
2008-05-29 |
2012-03-15 |
Hanall Biopharma Co Ltd |
Modifizierte erythropoietin (epo)-polypeptide mit erhöhter proteaseresistenz und pharmazeutische zusammensetzungen daraus
|
WO2009148528A2
(en)
|
2008-05-30 |
2009-12-10 |
Millennium Pharmaceuticals, Inc. |
Assessment of chromosomal alterations to predict clinical outcome of bortezomib treatment
|
WO2009147641A2
(en)
|
2008-06-06 |
2009-12-10 |
Wockhardt Research Centre |
A device and a system for delivery of biological material
|
PL215513B1
(pl)
|
2008-06-06 |
2013-12-31 |
Univ Warszawski |
Nowe boranofosforanowe analogi dinukleotydów, ich zastosowanie, czasteczka RNA, sposób otrzymywania RNA oraz sposób otrzymywania peptydów lub bialka
|
TWI451876B
(zh)
|
2008-06-13 |
2014-09-11 |
Lilly Co Eli |
聚乙二醇化之離脯胰島素化合物
|
PT2774608T
(pt)
|
2008-06-16 |
2020-01-17 |
Pfizer |
Nanopartículas poliméricas carregadas com fármaco e métodos de produção e utilização das mesmas
|
US8613951B2
(en)
|
2008-06-16 |
2013-12-24 |
Bind Therapeutics, Inc. |
Therapeutic polymeric nanoparticles with mTor inhibitors and methods of making and using same
|
EP2309991B1
(en)
|
2008-06-16 |
2019-03-06 |
Pfizer Inc |
Therapeutic polymeric nanoparticles comprising vinca alkaloids and methods of making and using same
|
HUE035770T2
(en)
|
2008-06-16 |
2018-05-28 |
Pfizer |
Process for the preparation of diblock copolymers functionalized with targeting material for use in the preparation of therapeutic nanoparticles
|
US7799016B2
(en)
|
2008-06-20 |
2010-09-21 |
Pharmaco-Kinesis Corporation |
Magnetic breather pump and a method for treating a brain tumor using the same
|
EP2320885B1
(en)
|
2008-06-25 |
2016-10-19 |
Fe3 Medical, Inc |
Patches for the transdermal delivery of a therapeutically effective amount of iron
|
US20100009424A1
(en)
|
2008-07-14 |
2010-01-14 |
Natasha Forde |
Sonoporation systems and methods
|
EP2313085A2
(en)
|
2008-07-15 |
2011-04-27 |
Novartis AG |
Immunogenic amphipathic peptide compositions
|
WO2010009065A2
(en)
|
2008-07-15 |
2010-01-21 |
Novartis Ag |
Amphipathic peptide compositions
|
WO2010021865A1
(en)
|
2008-08-18 |
2010-02-25 |
Merck Sharp & Dohme Corp. |
Novel lipid nanoparticles and novel components for delivery of nucleic acids
|
US8357118B2
(en)
|
2008-08-26 |
2013-01-22 |
Cook Medical Technologies Llc |
Balloon catheters having a plurality of needles for the injection of one or more therapeutic agents
|
AU2009290137A1
(en)
|
2008-09-03 |
2010-03-11 |
Xenome Ltd |
Libraries of peptide conjugates and methods for making them
|
JP5714490B2
(ja)
|
2008-09-06 |
2015-05-07 |
ケムジーンズ コーポレーション |
Rna合成、リバース方向での合成rnaためのホスホラミダイト、及びrnaオリゴマーの合成のための5’から3’方向に対する結合形成によるオリゴヌクレオチドを調製する方法
|
US20120100558A1
(en)
|
2008-09-08 |
2012-04-26 |
Hanash Samir M |
Lung cancer diagnosis
|
US20100087337A1
(en)
|
2008-09-10 |
2010-04-08 |
Bind Biosciences, Inc. |
High Throughput Fabrication of Nanoparticles
|
TW201438738A
(zh)
|
2008-09-16 |
2014-10-16 |
Genentech Inc |
治療進展型多發性硬化症之方法
|
WO2010033906A2
(en)
|
2008-09-19 |
2010-03-25 |
President And Fellows Of Harvard College |
Efficient induction of pluripotent stem cells using small molecule compounds
|
WO2010037408A1
(en)
|
2008-09-30 |
2010-04-08 |
Curevac Gmbh |
Composition comprising a complexed (m)rna and a naked mrna for providing or enhancing an immunostimulatory response in a mammal and uses thereof
|
WO2010042490A1
(en)
|
2008-10-06 |
2010-04-15 |
Boston Medical Center Corporation |
A single lentiviral vector system for induced pluripotent (ips) stem cells derivation
|
PL2350043T3
(pl)
|
2008-10-09 |
2014-09-30 |
Tekmira Pharmaceuticals Corp |
Ulepszone aminolipidy i sposoby dostarczania kwasów nukleinowych
|
RU2011114561A
(ru)
|
2008-10-10 |
2012-11-20 |
Милакс Холдинг Са (Lu) |
Ввод лекарственных препаратов
|
US8535655B2
(en)
|
2008-10-10 |
2013-09-17 |
Polyactiva Pty Ltd. |
Biodegradable polymer—bioactive moiety conjugates
|
US8343498B2
(en)
|
2008-10-12 |
2013-01-01 |
Massachusetts Institute Of Technology |
Adjuvant incorporation in immunonanotherapeutics
|
ITVI20080239A1
(it)
|
2008-10-14 |
2010-04-15 |
Antoine Assaf |
Apparato medicale per iniezioni multiple.
|
US8603532B2
(en)
|
2008-10-20 |
2013-12-10 |
Massachusetts Institute Of Technology |
Nanostructures for drug delivery
|
WO2010047839A1
(en)
|
2008-10-25 |
2010-04-29 |
Aura Biosciences |
Modified plant virus particles and uses therefor
|
MX353900B
(es)
|
2008-11-07 |
2018-02-01 |
Massachusetts Inst Technology |
Lipidoides de aminoalcohol y usos de los mismos.
|
JP5832898B2
(ja)
|
2008-11-10 |
2015-12-16 |
テクミラ ファーマシューティカルズ コーポレイションTekmira Pharmaceuticals Corporation |
治療薬を送達するための新規な脂質及び組成物
|
WO2010057203A2
(en)
|
2008-11-17 |
2010-05-20 |
The Board Of Regents Of The University Of Texas System |
Hdl particles for delivery of nucleic acids
|
TW201021852A
(en)
|
2008-11-17 |
2010-06-16 |
Enzon Pharmaceuticals Inc |
Releasable fusogenic lipids for nucleic acids delivery systems
|
EP2191840A1
(en)
|
2008-11-28 |
2010-06-02 |
Sanofi-Aventis |
Antitumor combinations containing antibodies recognizing specifically CD38 and melphalan
|
KR101073875B1
(ko)
|
2008-11-28 |
2011-10-14 |
한국생명공학연구원 |
대장암 진단 마커 및 이를 이용한 대장암 진단방법
|
JP5855462B2
(ja)
|
2008-12-10 |
2016-02-09 |
アルナイラム ファーマシューティカルズ, インコーポレイテッドAlnylam Pharmaceuticals, Inc. |
GNAQを標的としたdsRNA組成物および発現を阻害するための方法
|
EP2196476A1
(en)
|
2008-12-10 |
2010-06-16 |
Novartis Ag |
Antibody formulation
|
US8512964B2
(en)
|
2008-12-12 |
2013-08-20 |
The Regents Of The University Of California |
Targets for treatment of hypercholesterolemia
|
WO2010068866A2
(en)
|
2008-12-12 |
2010-06-17 |
Bind Biosciences |
Therapeutic particles suitable for parenteral administration and methods of making and using same
|
JP2012512175A
(ja)
|
2008-12-15 |
2012-05-31 |
バインド バイオサイエンシズ インコーポレイテッド |
治療薬を徐放するための長時間循環性ナノ粒子
|
KR20110110086A
(ko)
*
|
2008-12-24 |
2011-10-06 |
가부시키가이샤 바이오메드코어 |
리포솜의 제조방법 및 콜레스테롤의 용해방법
|
WO2010080724A1
(en)
|
2009-01-12 |
2010-07-15 |
Merck Sharp & Dohme Corp. |
Novel lipid nanoparticles and novel components for delivery of nucleic acids
|
BRPI1006829A2
(pt)
|
2009-01-16 |
2016-10-25 |
Glaxosmithkline Llc |
tratamento de um câncer empregando uma combinação de bendamustina e um anticorpo anti-cd20
|
WO2010084371A1
(en)
|
2009-01-26 |
2010-07-29 |
Mitoprod |
Novel circular interfering rna molecules
|
US20120101148A1
(en)
|
2009-01-29 |
2012-04-26 |
Alnylam Pharmaceuticals, Inc. |
lipid formulation
|
US8669085B2
(en)
|
2009-02-05 |
2014-03-11 |
Ut-Battelle, Llc |
Transformation of gram positive bacteria by sonoporation
|
WO2010088927A1
(en)
|
2009-02-09 |
2010-08-12 |
Curevac Gmbh |
Use of pei for the improvement of endosomal release and expression of transfected nucleic acids, complexed with cationic or polycationic compounds
|
US20140141089A1
(en)
|
2009-02-11 |
2014-05-22 |
Colorado School Of Mines |
Nanoparticles, Compositions Thereof, and Methods of Use, and Methods of Making the Same
|
JP5735927B2
(ja)
|
2009-02-24 |
2015-06-17 |
ザ スクリプス リサーチ インスティテュート |
タンパク質生産の増強のためのmRNAの一次構造の再操作
|
WO2010102065A1
(en)
|
2009-03-05 |
2010-09-10 |
Bend Research, Inc. |
Pharmaceutical compositions of dextran polymer derivatives
|
WO2010141135A2
(en)
|
2009-03-05 |
2010-12-09 |
Trustees Of Boston University |
Bacteriophages expressing antimicrobial peptides and uses thereof
|
AU2010223888A1
(en)
|
2009-03-13 |
2011-10-06 |
Egen, Inc. |
Compositions and methods for the delivery of biologically active RNAs
|
WO2010108108A2
(en)
|
2009-03-20 |
2010-09-23 |
Egen, Inc. |
Polyamine derivatives
|
WO2010111290A1
(en)
|
2009-03-23 |
2010-09-30 |
University Of Utah Research Foundation |
Methods and compositions related to modified guanine bases for controlling off-target effects in rna interference
|
JP5622254B2
(ja)
|
2009-03-31 |
2014-11-12 |
国立大学法人東京大学 |
二本鎖リボ核酸ポリイオンコンプレックス
|
WO2011127032A1
(en)
|
2010-04-05 |
2011-10-13 |
University Of Chicago |
Compositions and methods related to protein a (spa) antibodies as an enhancer of immune response
|
SI3281947T1
(sl)
|
2009-04-03 |
2020-07-31 |
The University Of Chicago |
Sestave in metode v zvezi z variantami proteina A (SPA)
|
US9724404B2
(en)
|
2009-04-13 |
2017-08-08 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
HPV particles and uses thereof
|
EP2419137A4
(en)
|
2009-04-17 |
2013-01-09 |
Biogen Idec Inc |
COMPOSITIONS AND METHOD FOR TREATING ACUTE MYELOGENIC LEUKEMIA
|
EP2421561A2
(en)
|
2009-04-21 |
2012-02-29 |
Selecta Biosciences, Inc. |
Immunonanotherapeutics providing a th1-biased response
|
US20100273220A1
(en)
|
2009-04-22 |
2010-10-28 |
Massachusetts Institute Of Technology |
Innate immune suppression enables repeated delivery of long rna molecules
|
EA027071B1
(ru)
|
2009-04-27 |
2017-06-30 |
Новартис Аг |
АНТИТЕЛО К ActRIIB И СОДЕРЖАЩАЯ ЕГО КОМПОЗИЦИЯ
|
US8715736B2
(en)
|
2009-04-30 |
2014-05-06 |
Florida Agricultural And Mechanical University |
Nanoparticle formulations for skin delivery
|
WO2010127159A2
(en)
|
2009-04-30 |
2010-11-04 |
Intezyne Technologies, Incorporated |
Polymeric micelles for polynucleotide encapsulation
|
NZ711583A
(en)
|
2009-05-05 |
2017-03-31 |
Arbutus Biopharma Corp |
Lipid compositions
|
AU2010245933B2
(en)
|
2009-05-05 |
2016-06-16 |
Arbutus Biopharma Corporation |
Methods of delivering oligonucleotides to immune cells
|
DE202009007116U1
(de)
|
2009-05-18 |
2010-10-14 |
Amoena Medizin-Orthopädie-Technik GmbH |
Antidekubituskissen
|
AU2010254549B2
(en)
|
2009-05-27 |
2016-10-20 |
Selecta Biosciences, Inc. |
Nanocarriers possessing components with different rates of release
|
US8574835B2
(en)
|
2009-05-29 |
2013-11-05 |
Life Technologies Corporation |
Scaffolded nucleic acid polymer particles and methods of making and using
|
CN102625696B
(zh)
|
2009-06-10 |
2015-06-03 |
阿尔尼拉姆医药品有限公司 |
改进的脂质制剂
|
EP2440556A1
(en)
|
2009-06-10 |
2012-04-18 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of phosphatidylinositol 3-kinase
|
MX2011013421A
(es)
|
2009-06-15 |
2012-03-16 |
Alnylam Pharmaceuticals Inc |
Arnds formulado con lipido de direccionamiento del gen pcsk9.
|
US20110097329A1
(en)
|
2009-06-26 |
2011-04-28 |
Massachusetts Institute Of Technology |
Compositions and methods for treating cancer and modulating stress granule formation
|
JP5766188B2
(ja)
|
2009-07-01 |
2015-08-19 |
プロチバ バイオセラピューティクス インコーポレイティッド |
固形腫瘍に治療剤を送達するための脂質製剤
|
US8569256B2
(en)
|
2009-07-01 |
2013-10-29 |
Protiva Biotherapeutics, Inc. |
Cationic lipids and methods for the delivery of therapeutic agents
|
US20110300205A1
(en)
|
2009-07-06 |
2011-12-08 |
Novartis Ag |
Self replicating rna molecules and uses thereof
|
CN105255881A
(zh)
|
2009-07-31 |
2016-01-20 |
埃泽瑞斯公司 |
用于蛋白质表达的具有未修饰和修饰核苷酸的组合的rna
|
EP2281579A1
(en)
|
2009-08-05 |
2011-02-09 |
BioNTech AG |
Vaccine composition comprising 5'-Cap modified RNA
|
EP3072881A1
(en)
|
2009-08-20 |
2016-09-28 |
Sirna Therapeutics, Inc. |
Novel cationic lipids with various head groups for oligonucleotide delivery
|
ES2641892T3
(es)
|
2009-08-26 |
2017-11-14 |
Selecta Biosciences, Inc. |
Composiciones que inducen la ayuda de las células T
|
US20110053829A1
(en)
|
2009-09-03 |
2011-03-03 |
Curevac Gmbh |
Disulfide-linked polyethyleneglycol/peptide conjugates for the transfection of nucleic acids
|
US20110070227A1
(en)
|
2009-09-18 |
2011-03-24 |
Anna-Marie Novotney-Barry |
Treatment of Autoimmune and Inflammatory Diseases
|
WO2011043913A2
(en)
|
2009-10-08 |
2011-04-14 |
Merck Sharp & Dohme Corp. |
Novel cationic lipids with short lipid chains for oligonucleotide delivery
|
US8859284B2
(en)
|
2009-10-22 |
2014-10-14 |
The United States Of America, As Represented By The Secretary Of The Navy |
Delivery of nanoparticles to neurons
|
CA2816925C
(en)
|
2009-11-04 |
2023-01-10 |
The University Of British Columbia |
Nucleic acid-containing lipid particles and related methods
|
US8449916B1
(en)
|
2009-11-06 |
2013-05-28 |
Iowa State University Research Foundation, Inc. |
Antimicrobial compositions and methods
|
WO2011060250A1
(en)
|
2009-11-13 |
2011-05-19 |
Bend Research, Inc. |
Cationic dextran polymer derivatives
|
WO2011062965A2
(en)
|
2009-11-18 |
2011-05-26 |
University Of Washington Through Its Center For Commercialization |
Targeting monomers and polymers having targeting blocks
|
US8530429B2
(en)
|
2009-11-24 |
2013-09-10 |
Arch Cancer Therapeutics, Inc. |
Brain tumor targeting peptides and methods
|
DK3338765T3
(en)
*
|
2009-12-01 |
2019-03-04 |
Translate Bio Inc |
STEROID DERIVATIVE FOR THE SUPPLY OF MRNA IN HUMANGENETIC DISEASES
|
US20110245756A1
(en)
|
2009-12-03 |
2011-10-06 |
Rishi Arora |
Devices for material delivery, electroporation, sonoporation, and/or monitoring electrophysiological activity
|
DE102009056884B4
(de)
|
2009-12-03 |
2021-03-18 |
Novartis Ag |
Impfstoff-Adjuvantien und verbesserte Verfahren zur Herstellung derselben
|
CA3121739A1
(en)
|
2009-12-06 |
2011-06-09 |
Bioverativ Therapeutics Inc. |
Factor viii-fc chimeric and hybrid polypeptides, and methods of use thereof
|
CA3044884A1
(en)
|
2009-12-07 |
2011-06-16 |
Arbutus Biopharma Corporation |
Compositions for nucleic acid delivery
|
US20130189741A1
(en)
|
2009-12-07 |
2013-07-25 |
Cellscript, Inc. |
Compositions and methods for reprogramming mammalian cells
|
KR102171849B1
(ko)
|
2009-12-07 |
2020-10-30 |
더 트러스티스 오브 더 유니버시티 오브 펜실바니아 |
세포 리프로그래밍을 위한 정제된 변형 rna를 포함하는 rna 제제
|
WO2011069529A1
(en)
|
2009-12-09 |
2011-06-16 |
Curevac Gmbh |
Mannose-containing solution for lyophilization, transfection and/or injection of nucleic acids
|
WO2011069528A1
(en)
|
2009-12-09 |
2011-06-16 |
Curevac Gmbh |
Lyophilization of nucleic acids in lactate-containing solutions
|
JP5891175B2
(ja)
|
2009-12-11 |
2016-03-22 |
バインド セラピューティックス インコーポレイテッド |
治療用粒子の凍結乾燥に対する安定製剤
|
US9295649B2
(en)
|
2009-12-15 |
2016-03-29 |
Bind Therapeutics, Inc. |
Therapeutic polymeric nanoparticle compositions with high glass transition temperature or high molecular weight copolymers
|
EP2512487A4
(en)
|
2009-12-15 |
2013-08-07 |
|
THERAPEUTIC POLYMERNANOPARTICLES WITH CORTICOSTEROIDS AND METHOD FOR THE PRODUCTION AND USE THEREOF
|
EA201290498A1
(ru)
|
2009-12-15 |
2013-01-30 |
Байнд Байосайенсиз, Инк. |
Терапевтические полимерные наночастицы, включающие эпотилон, и способы их получения и применения
|
DE102009058769A1
(de)
|
2009-12-16 |
2011-06-22 |
MagForce Nanotechnologies AG, 10589 |
Temperaturabhängige Aktivierung von katalytischen Nukleinsäuren zur kontrollierten Wirkstofffreisetzung
|
EA201290506A1
(ru)
|
2009-12-16 |
2013-03-29 |
Брихэм Энд Уимен'З Хоспитал, Инк. |
Частицы для доставки множества агентов
|
CA2784568A1
(en)
|
2009-12-18 |
2011-06-23 |
Martin A. Maier |
Lipid particles for delivery of nucleic acids
|
EP2338520A1
(de)
|
2009-12-21 |
2011-06-29 |
Ludwig Maximilians Universität |
Konjugat mit Zielfindungsligand und dessen Verwendung
|
US20110200582A1
(en)
|
2009-12-23 |
2011-08-18 |
Novartis Ag |
Lipids, lipid compositions, and methods of using them
|
US20110171248A1
(en)
|
2010-01-08 |
2011-07-14 |
Selecta Biosciences, Inc. |
Synthetic virus-like particles conjugated to human papillomavirus capsid peptides for use as vaccines
|
WO2011088309A1
(en)
|
2010-01-14 |
2011-07-21 |
Regulus Therapeutics Inc. |
Microrna compositions and methods
|
US20130116419A1
(en)
|
2010-01-22 |
2013-05-09 |
Daniel Zewge |
Post-synthetic chemical modification of rna at the 2'-position of the ribose ring via "click" chemistry
|
CA2787598A1
(en)
|
2010-01-24 |
2012-06-21 |
Novartis Ag |
Irradiated biodegradable polymer microparticles
|
DK2539451T3
(da)
|
2010-02-24 |
2016-04-04 |
Arrowhead Res Corp |
Sammensætninger til målrettet tilførsel af siRNA
|
CA2791278C
(en)
|
2010-02-25 |
2015-11-24 |
The Johns Hopkins University |
Sustained delivery of therapeutic agents to an eye compartment
|
US20130133483A1
(en)
|
2010-03-08 |
2013-05-30 |
University Of Rochester |
Synthesis of Nanoparticles Using Reducing Gases
|
WO2011116072A1
(en)
|
2010-03-16 |
2011-09-22 |
Escape Therapeutics, Inc. |
Hybrid hydrogel scaffold compositions and methods of use
|
AU2011227264A1
(en)
|
2010-03-16 |
2012-10-04 |
University Of Utah Research Foundation |
Cleavable modifications to reducible poly (amido ethylenimines)s to enhance nucleotide delivery
|
US20110230816A1
(en)
|
2010-03-18 |
2011-09-22 |
Tyco Healthcare Group Lp |
Gels for Transdermal Delivery
|
US20130005797A1
(en)
|
2010-03-18 |
2013-01-03 |
Merck Sharp & Dohme Corp. |
Endosomolytic poly(amidoamine) disulfide polymers for the delivery of oligonucleotides
|
US9149432B2
(en)
|
2010-03-19 |
2015-10-06 |
Massachusetts Institute Of Technology |
Lipid vesicle compositions and methods of use
|
CN103108642B
(zh)
*
|
2010-03-24 |
2015-09-23 |
雷克西制药公司 |
皮肤与纤维化症候中的rna干扰
|
GB201005005D0
(en)
|
2010-03-25 |
2010-05-12 |
Angeletti P Ist Richerche Bio |
New vaccine
|
US8207290B2
(en)
|
2010-03-26 |
2012-06-26 |
Cerulean Pharma Inc. |
Methods and systems for generating nanoparticles
|
US8349308B2
(en)
|
2010-03-26 |
2013-01-08 |
Mersana Therapeutics, Inc. |
Modified polymers for delivery of polynucleotides, method of manufacture, and methods of use thereof
|
US20110247090A1
(en)
|
2010-04-02 |
2011-10-06 |
Intrexon Corporation |
Synthetic 5'UTRs, Expression Vectors, and Methods for Increasing Transgene Expression
|
WO2011127316A1
(en)
|
2010-04-07 |
2011-10-13 |
Novartis Ag |
Method for generating a parvovirus b19 virus-like particle
|
WO2011127255A1
(en)
|
2010-04-08 |
2011-10-13 |
Merck Sharp & Dohme Corp. |
Preparation of lipid nanoparticles
|
CA2795695A1
(en)
|
2010-04-09 |
2011-10-13 |
The University Of Tokyo |
Microrna-controlled recombinant vaccinia virus and use thereof
|
EP2555752B1
(en)
|
2010-04-09 |
2019-06-26 |
Pacira Pharmaceuticals, Inc. |
Method for formulating multivesicular liposomes
|
US20110262491A1
(en)
|
2010-04-12 |
2011-10-27 |
Selecta Biosciences, Inc. |
Emulsions and methods of making nanocarriers
|
KR101196667B1
(ko)
|
2010-04-15 |
2012-11-02 |
포항공과대학교 산학협력단 |
피에이치 민감성 금속 나노 입자를 이용한 항암제 전달 시스템
|
EP2558571A4
(en)
|
2010-04-16 |
2014-09-24 |
Immune Disease Inst Inc |
DELAYED POLYPEPTIDE EXPRESSION FROM MODIFIED SYNTHETIC RNAS AND USES THEREOF
|
SI2558577T1
(sl)
|
2010-04-16 |
2019-05-31 |
Nuevolution A/S |
Bifunkcionalni kompleksi in metode za pripravo in uporabo takšnih kompleksov
|
EP2377938A1
(en)
|
2010-04-16 |
2011-10-19 |
Eukarys |
Capping-prone RNA polymerase enzymes and their applications
|
WO2011133868A2
(en)
|
2010-04-22 |
2011-10-27 |
Alnylam Pharmaceuticals, Inc. |
Conformationally restricted dinucleotide monomers and oligonucleotides
|
US9629979B2
(en)
|
2010-04-28 |
2017-04-25 |
Sanovas, Inc. |
Pressure/Vacuum actuated catheter drug delivery probe
|
EP2563455A4
(en)
|
2010-04-28 |
2014-02-19 |
Kimberly Clark Co |
METHOD FOR INCREASING THE PERMEABILITY OF AN EPITHELIAL BARRIER
|
US20130156845A1
(en)
|
2010-04-29 |
2013-06-20 |
Alnylam Pharmaceuticals, Inc. |
Lipid formulated single stranded rna
|
US20130052644A1
(en)
|
2010-04-30 |
2013-02-28 |
Baltazar Gomez-Mancilla |
Predictive Markers Useful in the Treatment of Fragile X Syndrome (FXS)
|
US9254327B2
(en)
|
2010-05-10 |
2016-02-09 |
Alnylam Pharmaceuticals, Inc. |
Methods and compositions for delivery of active agents
|
WO2011141704A1
(en)
|
2010-05-12 |
2011-11-17 |
Protiva Biotherapeutics, Inc |
Novel cyclic cationic lipids and methods of use
|
CA2799091A1
(en)
|
2010-05-12 |
2011-11-17 |
Protiva Biotherapeutics, Inc. |
Cationic lipids and methods of use thereof
|
EP2387999A1
(en)
|
2010-05-21 |
2011-11-23 |
CureVac GmbH |
Histidine-containing solution for transfection and/or injection of nucleic acids and uses thereof
|
JP2013531634A
(ja)
|
2010-05-24 |
2013-08-08 |
メルク・シャープ・エンド・ドーム・コーポレイション |
オリゴヌクレオチド送達のための新規なアミノアルコールカチオン性脂質
|
WO2011150258A1
(en)
|
2010-05-26 |
2011-12-01 |
Selecta Biosciences, Inc. |
Dose selection of adjuvanted synthetic nanocarriers
|
JP5957646B2
(ja)
|
2010-06-04 |
2016-07-27 |
サーナ・セラピューティクス・インコーポレイテッドSirna Therapeutics,Inc. |
オリゴヌクレオチド送達のための新規な低分子量カチオン性脂質
|
AU2011267078B2
(en)
|
2010-06-14 |
2014-09-25 |
F. Hoffmann-La Roche Ag |
Cell-penetrating peptides and uses therof
|
US20120158100A1
(en)
|
2010-06-21 |
2012-06-21 |
Kevin Schomacker |
Driving Microneedle Arrays into Skin and Delivering RF Energy
|
US20130236968A1
(en)
|
2010-06-21 |
2013-09-12 |
Alnylam Pharmaceuticals, Inc. |
Multifunctional copolymers for nucleic acid delivery
|
US10478483B2
(en)
|
2010-06-25 |
2019-11-19 |
Glaxosmithkline Biologicals Sa |
Combinations of meningococcal factor H binding proteins
|
US9066971B2
(en)
|
2010-07-01 |
2015-06-30 |
Postech Academy-Industry Foundation |
Method for treating and diagnosing cancer by using cell-derived microvesicles
|
EP2588120B1
(en)
|
2010-07-02 |
2017-11-15 |
The University of Chicago |
Compositions and methods related to protein a (spa) variants
|
KR101130137B1
(ko)
|
2010-07-02 |
2012-03-28 |
연세대학교 산학협력단 |
발광다이오드 모듈
|
US8353871B2
(en)
|
2010-07-05 |
2013-01-15 |
Roller Jet Ltd. |
Drug delivery device with needles and roller
|
RS63817B1
(sr)
|
2010-07-06 |
2023-01-31 |
Glaxosmithkline Biologicals Sa |
Čestice za isporuku slične virionu za molekule samoreplicirajuće rnk
|
WO2012006369A2
(en)
|
2010-07-06 |
2012-01-12 |
Novartis Ag |
Immunisation of large mammals with low doses of rna
|
DK3243526T3
(da)
|
2010-07-06 |
2020-02-17 |
Glaxosmithkline Biologicals Sa |
Levering af rna til at udløse flere immunsignalveje
|
ES2649896T3
(es)
|
2010-07-06 |
2018-01-16 |
Glaxosmithkline Biologicals Sa |
Emulsiones catiónicas de aceite en agua
|
CN103153284B
(zh)
|
2010-07-06 |
2015-11-25 |
诺华股份有限公司 |
含有其pKa值有利于RNA递送的脂质的脂质体
|
US9770463B2
(en)
|
2010-07-06 |
2017-09-26 |
Glaxosmithkline Biologicals Sa |
Delivery of RNA to different cell types
|
US9192661B2
(en)
|
2010-07-06 |
2015-11-24 |
Novartis Ag |
Delivery of self-replicating RNA using biodegradable polymer particles
|
MX356527B
(es)
|
2010-07-09 |
2018-06-01 |
Bioverativ Therapeutics Inc |
Polipeptidos de factor ix y metodos para usarlos.
|
US9611310B2
(en)
|
2010-07-09 |
2017-04-04 |
Bioverativ Therapeutics Inc. |
Systems for factor VIII processing and methods thereof
|
US20130177523A1
(en)
|
2010-07-13 |
2013-07-11 |
University Of Utah Research Foundation |
Gold particles and methods of making and using the same in cancer treatment
|
GB201012410D0
(en)
|
2010-07-23 |
2010-09-08 |
Medical Res Council |
Intracellular immunity
|
DE102010032758B4
(de)
|
2010-07-29 |
2012-02-23 |
Fujitsu Technology Solutions Intellectual Property Gmbh |
Computersystem, Verfahren zum Programmieren einer Echtzeituhr und Computerprogrammprodukt
|
CA2801523C
(en)
|
2010-07-30 |
2021-08-03 |
Curevac Gmbh |
Complexation of nucleic acids with disulfide-crosslinked cationic components for transfection and immunostimulation
|
WO2012016269A1
(en)
|
2010-08-02 |
2012-02-09 |
Curtin University Of Technology |
Determining location of, and imaging, a subsurface boundary
|
US8822663B2
(en)
|
2010-08-06 |
2014-09-02 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
US9121065B2
(en)
|
2010-08-09 |
2015-09-01 |
The Trustees Of The University Of Pennsylvania |
Nanoparticle-oligonucleotide hybrid structures and methods of use thereof
|
WO2012019630A1
(en)
|
2010-08-13 |
2012-02-16 |
Curevac Gmbh |
Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded protein
|
AU2011291582A1
(en)
|
2010-08-20 |
2013-03-07 |
Cerulean Pharma Inc. |
Conjugates, particles, compositions, and related methods
|
WO2012024595A2
(en)
|
2010-08-20 |
2012-02-23 |
University Of Washington |
Circumferential aerosol device for delivering drugs to olfactory epithelium and brain
|
WO2012024621A2
(en)
|
2010-08-20 |
2012-02-23 |
Selecta Biosciences, Inc. |
Synthetic nanocarrier vaccines comprising peptides obtained or derived from human influenza a virus hemagglutinin
|
EP2605792B1
(en)
|
2010-08-20 |
2014-12-10 |
Novartis AG |
Soluble needle arrays for delivery of influenza vaccines
|
WO2012027365A2
(en)
|
2010-08-23 |
2012-03-01 |
Selecta Biosciences, Inc. |
Targeted multi-epitope dosage forms for induction of an immune response to antigens
|
CN103080582B
(zh)
|
2010-08-24 |
2015-10-14 |
Gkn动力传动系统国际有限责任公司 |
用于万向节特别是用于等速万向节的具有过渡区域的罩
|
BR112013004879A2
(pt)
|
2010-08-31 |
2018-04-24 |
Novartis Ag |
lipossomas pequenos para entrega de rna que codifica imunogénio
|
JP6165629B2
(ja)
|
2010-08-31 |
2017-07-19 |
キヤノン ユー.エス. ライフ サイエンシズ, インコーポレイテッドCanon U.S. Life Sciences, Inc. |
流体混合及びチップインターフェースのための方法、デバイス、及びシステム
|
EP2611420B1
(en)
|
2010-08-31 |
2019-03-27 |
GlaxoSmithKline Biologicals SA |
Lipids suitable for liposomal delivery of protein-coding rna
|
HUE058667T2
(hu)
|
2010-08-31 |
2022-09-28 |
Glaxosmithkline Biologicals Sa |
Pegilált liposzómák immunogént kódoló RNS szállítására
|
JP2013541510A
(ja)
|
2010-08-31 |
2013-11-14 |
メルク・シャープ・エンド・ドーム・コーポレイション |
新規の単一の化学物質、およびオリゴヌクレオチドの送達方法
|
CA3109036C
(en)
|
2010-08-31 |
2023-08-01 |
Theraclone Sciences, Inc. |
Human immunodeficiency virus (hiv)-neutralizing antibodies
|
WO2012031205A2
(en)
|
2010-09-03 |
2012-03-08 |
The Brigham And Women's Hospital, Inc. |
Lipid-polymer hybrid particles
|
WO2012034067A1
(en)
|
2010-09-09 |
2012-03-15 |
The University Of Chicago |
Methods and compositions involving protective staphylococcal antigens
|
US20130236419A1
(en)
|
2010-09-09 |
2013-09-12 |
The University Of Chicago |
Compositions and methods related to attenuated staphylococcal strains
|
US10307372B2
(en)
|
2010-09-10 |
2019-06-04 |
The Johns Hopkins University |
Rapid diffusion of large polymeric nanoparticles in the mammalian brain
|
US8466122B2
(en)
|
2010-09-17 |
2013-06-18 |
Protiva Biotherapeutics, Inc. |
Trialkyl cationic lipids and methods of use thereof
|
MX349088B
(es)
|
2010-09-20 |
2017-07-10 |
Merck Sharp & Dohme |
Lípidos catiónicos novedosos de bajo peso molecular para la entrega de oligonucleótidos.
|
US20130183718A1
(en)
|
2010-09-21 |
2013-07-18 |
RibpxX GmbH |
Method for Synthesizing RNA using DNA Template
|
BR112013008697A2
(pt)
|
2010-09-24 |
2016-06-21 |
Massachusetts Inst Technology |
géis nanoestruturados capazes de liberação controlada de agentes encapsulados
|
WO2012050975A2
(en)
|
2010-09-29 |
2012-04-19 |
The University Of North Carolina At Chapel Hill |
Novel circular mammalian rna molecules and uses thereof
|
CN103260611A
(zh)
|
2010-09-30 |
2013-08-21 |
默沙东公司 |
用于寡核苷酸递送的低分子量阳离子脂质
|
EP2625189B1
(en)
|
2010-10-01 |
2018-06-27 |
ModernaTX, Inc. |
Engineered nucleic acids and methods of use thereof
|
WO2013086505A1
(en)
|
2011-12-09 |
2013-06-13 |
Vanderbilt University |
Integrated organ-on-chip system and applications of the same
|
EP2627351B1
(en)
|
2010-10-11 |
2018-12-26 |
GlaxoSmithKline Biologicals SA |
Antigen delivery platforms
|
US9782342B2
(en)
|
2010-10-11 |
2017-10-10 |
Wichita State University |
Composite magnetic nanoparticle drug delivery system
|
US9029590B2
(en)
|
2010-10-21 |
2015-05-12 |
Sirna Therapeutics, Inc. |
Low molecular weight cationic lipids for oligonucleotide delivery
|
EA201390600A1
(ru)
|
2010-10-22 |
2013-09-30 |
Байнд Терапьютикс, Инк. |
Терапевтические наночастицы с сополимерами с большим молекулярным весом
|
JP6018575B2
(ja)
|
2010-10-29 |
2016-11-02 |
メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. |
デングウイルス組換えサブユニットスワクチン
|
AU2011323250B2
(en)
|
2010-11-05 |
2015-11-19 |
The Johns Hopkins University |
Compositions and methods relating to reduced mucoadhesion
|
DK2635265T3
(en)
|
2010-11-05 |
2018-07-16 |
Sirna Therapeutics Inc |
New low molecular weight cyclic amine-containing cationic lipids for oligonucleotide delivery
|
US9994443B2
(en)
|
2010-11-05 |
2018-06-12 |
Selecta Biosciences, Inc. |
Modified nicotinic compounds and related methods
|
AU2011326732B2
(en)
|
2010-11-09 |
2016-07-21 |
The Regents Of The University Of California |
Skin permeating and cell entering (space) peptides and methods of use thereof
|
PL3536703T3
(pl)
|
2010-11-12 |
2021-10-25 |
The Trustees Of The University Of Pennsylvania |
Konsensusowe antygeny gruczołu krokowego, kodujące je cząsteczki kwasu nukleinowego i ich zastosowania
|
AU2011329850B2
(en)
|
2010-11-16 |
2017-03-02 |
Selecta Biosciences, Inc. |
Immunostimulatory oligonucleotides
|
LT2640842T
(lt)
|
2010-11-17 |
2018-09-10 |
Aduro Biotech, Inc. |
Būdai ir kompozicijos, skirti indukuoti imuninį atsaką į egfrviii
|
KR102100110B1
(ko)
|
2010-11-19 |
2020-04-14 |
이데라 파마슈티칼즈, 인코포레이티드 |
톨-유사 수용체 기반 면역 반응을 조절하기 위한 면역 조절 올리고뉴클레오타이드(iro) 화합물
|
WO2012068187A1
(en)
|
2010-11-19 |
2012-05-24 |
Merck Sharp & Dohme Corp. |
Poly(amide) polymers for the delivery of oligonucleotides
|
WO2012075040A2
(en)
|
2010-11-30 |
2012-06-07 |
Shire Human Genetic Therapies, Inc. |
mRNA FOR USE IN TREATMENT OF HUMAN GENETIC DISEASES
|
WO2012072096A1
(en)
|
2010-12-03 |
2012-06-07 |
Biontech Ag |
Method for cellular rna expression
|
CA2821622C
(en)
|
2010-12-16 |
2019-09-03 |
Sprna Gmbh |
Pharmaceutical composition consisting of rna having alkali metal as counter ion and formulated with dications
|
WO2012082574A1
(en)
|
2010-12-17 |
2012-06-21 |
Merck Sharp & Dohme Corp. |
Membrane lytic poly(amido amine) polymers for the delivery of oligonucleotides
|
US8501930B2
(en)
|
2010-12-17 |
2013-08-06 |
Arrowhead Madison Inc. |
Peptide-based in vivo siRNA delivery system
|
AU2011348204B2
(en)
|
2010-12-22 |
2017-03-02 |
President And Fellows Of Harvard College |
Continuous directed evolution
|
CN104328121A
(zh)
|
2010-12-29 |
2015-02-04 |
弗·哈夫曼-拉罗切有限公司 |
用于细胞内递送核酸的小分子缀合物
|
WO2012089225A1
(en)
|
2010-12-29 |
2012-07-05 |
Curevac Gmbh |
Combination of vaccination and inhibition of mhc class i restricted antigen presentation
|
US20120171229A1
(en)
|
2010-12-30 |
2012-07-05 |
Selecta Biosciences, Inc. |
Synthetic nanocarriers with reactive groups that release biologically active agents
|
US20120177701A1
(en)
|
2010-12-31 |
2012-07-12 |
Selecta Biosciences, Inc. |
Compositions comprising immunostimulatory nucleic acids and related methods
|
US10364440B2
(en)
|
2011-01-04 |
2019-07-30 |
Brown University |
Nanotubes as carriers of nucleic acids into cells
|
WO2012094574A2
(en)
|
2011-01-06 |
2012-07-12 |
The Johns Hopkins University |
Stabilized polyribonucleotide nanoparticles
|
US20140080766A1
(en)
|
2011-01-07 |
2014-03-20 |
Massachusetts Institute Of Technology |
Compositions and methods for macromolecular drug delivery
|
DK2663548T3
(en)
|
2011-01-11 |
2017-07-24 |
Alnylam Pharmaceuticals Inc |
PEGYLED LIPIDS AND THEIR USE FOR PHARMACEUTICAL SUPPLY
|
DE102011082231A1
(de)
|
2011-01-12 |
2012-07-12 |
Robert Bosch Gmbh |
Zündspule, insbesondere für kleinbauende Motoren
|
US20120189700A1
(en)
|
2011-01-19 |
2012-07-26 |
Zoraida Aguilar |
Nanoparticle Based Immunological Stimulation
|
WO2012101235A1
(en)
|
2011-01-26 |
2012-08-02 |
Cenix Bioscience Gmbh |
Delivery system and conjugates for compound delivery via naturally occurring intracellular transport routes
|
US10363309B2
(en)
|
2011-02-04 |
2019-07-30 |
Case Western Reserve University |
Targeted nanoparticle conjugates
|
WO2012109121A1
(en)
|
2011-02-07 |
2012-08-16 |
Purdue Research Foundation |
Carbohydrate nanoparticles for prolonged efficacy of antimicrobial peptide
|
WO2012116715A1
(en)
|
2011-03-02 |
2012-09-07 |
Curevac Gmbh |
Vaccination in newborns and infants
|
US20120207840A1
(en)
|
2011-02-10 |
2012-08-16 |
Aura Biosciences, Inc. |
Virion Derived Protein Nanoparticles For Delivering Diagnostic Or Therapeutic Agents For The Treatment Of Non-Melanoma Skin Cancer
|
CN103703013A
(zh)
|
2011-02-14 |
2014-04-02 |
斯威夫特生物科学公司 |
多核苷酸引物和探针
|
CA2827118A1
(en)
|
2011-02-15 |
2012-08-23 |
Merrimack Pharmaceuticals, Inc. |
Compositions and methods for delivering nucleic acid to a cell
|
US20140081012A1
(en)
|
2011-02-15 |
2014-03-20 |
The University Of North Carolina At Chapel Hill |
Nanoparticle, liposomes, polymers, agents and proteins modified with reversible linkers
|
EP2489371A1
(en)
|
2011-02-18 |
2012-08-22 |
Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria |
Carrier peptides for drug delivery
|
WO2012113413A1
(en)
|
2011-02-21 |
2012-08-30 |
Curevac Gmbh |
Vaccine composition comprising complexed immunostimulatory nucleic acids and antigens packaged with disulfide-linked polyethyleneglycol/peptide conjugates
|
JP6091435B2
(ja)
|
2011-02-22 |
2017-03-08 |
カリフォルニア インスティチュート オブ テクノロジー |
アデノ随伴ウイルス(aav)ベクターを用いたタンパク質の送達
|
US8696637B2
(en)
|
2011-02-28 |
2014-04-15 |
Kimberly-Clark Worldwide |
Transdermal patch containing microneedles
|
WO2012116714A1
(en)
|
2011-03-02 |
2012-09-07 |
Curevac Gmbh |
Vaccination in elderly patients
|
US20140112950A1
(en)
|
2011-03-02 |
2014-04-24 |
Manmohan Singh |
Combination vaccines with lower doses of antigen and/or adjuvant
|
CA2832807A1
(en)
|
2011-03-07 |
2012-09-13 |
Massachusetts Institute Of Technology |
Methods for transfecting cells with nucleic acids
|
US20120237565A1
(en)
|
2011-03-14 |
2012-09-20 |
Intezyne Technologies, Incorporated |
Pegylated polyplexes containing two or more different polymers for polynucleotide delivery
|
WO2012125680A1
(en)
|
2011-03-16 |
2012-09-20 |
Novartis Ag |
Methods of treating vasculitis using an il-17 binding molecule
|
WO2012125987A2
(en)
|
2011-03-17 |
2012-09-20 |
Massachusetts Institute Of Technology |
Delivery system
|
WO2012125812A1
(en)
|
2011-03-17 |
2012-09-20 |
Novartis Ag |
Fgfr and ligands thereof as biomarkers for breast cancer in hr positive subjects
|
US10357568B2
(en)
|
2011-03-24 |
2019-07-23 |
Glaxosmithkline Biologicals S.A. |
Adjuvant nanoemulsions with phospholipids
|
CN103458879A
(zh)
|
2011-03-25 |
2013-12-18 |
西莱克塔生物科技公司 |
渗透性介导释放型合成纳米载体
|
JP2014510533A
(ja)
|
2011-03-28 |
2014-05-01 |
ノバルティス アーゲー |
サイクリン依存性キナーゼ阻害剤に関連するマーカー
|
WO2012135025A2
(en)
|
2011-03-28 |
2012-10-04 |
Massachusetts Institute Of Technology |
Conjugated lipomers and uses thereof
|
JP2014511687A
(ja)
|
2011-03-31 |
2014-05-19 |
モデルナ セラピューティクス インコーポレイテッド |
工学操作された核酸の送達および製剤
|
AU2012237262A1
(en)
|
2011-03-31 |
2013-11-14 |
Ingell Technologies Holding B.V. |
Biodegradable compositions suitable for controlled release
|
US9901554B2
(en)
|
2011-03-31 |
2018-02-27 |
Ingell Technologies Holding B.V. |
Biodegradable compositions suitable for controlled release
|
EP3460064B8
(en)
|
2011-04-03 |
2024-03-20 |
The General Hospital Corporation d/b/a Massachusetts General Hospital |
Efficient protein expression in vivo using modified rna (mod-rna)
|
WO2012138530A1
(en)
|
2011-04-04 |
2012-10-11 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
2'-o-aminooxymethyl nucleoside derivatives for use in the synthesis and modification of nucleosides, nucleotides and oligonucleotides
|
WO2012142132A1
(en)
|
2011-04-11 |
2012-10-18 |
Life Technologies Corporation |
Polymer particles and methods of making and using same
|
WO2012142240A1
(en)
|
2011-04-13 |
2012-10-18 |
The Trustees Of The University Of Pennsylvania |
Coated mesoporous nanoparticles
|
WO2013158127A1
(en)
|
2012-04-16 |
2013-10-24 |
Molecular Transfer, Inc. |
Agents for improved delivery of nucleic acids to eukaryotic cells
|
US20140178894A1
(en)
|
2011-04-20 |
2014-06-26 |
Novartis Forschungsstiftung, Zweigniederlassung |
Culture medium suitable for the culture of undifferentiated cells
|
CA2834349A1
(en)
|
2011-04-26 |
2012-11-01 |
Molecular Express, Inc. |
Liposomal formulations
|
WO2012148684A1
(en)
|
2011-04-27 |
2012-11-01 |
President And Fellows Of Harvard College |
Cell-friendly inverse opal hydrogels for cell encapsulation, drug and protein delivery, and functional nanoparticle encapsulation
|
WO2012149536A1
(en)
|
2011-04-28 |
2012-11-01 |
The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. |
Neutralizing antibodies to nipah and hendra virus
|
CN103687590A
(zh)
|
2011-04-28 |
2014-03-26 |
Stc·Unm公司 |
用于靶向给药的多孔纳米颗粒支撑脂双层(原始细胞)及其使用方法
|
US9265815B2
(en)
|
2011-04-29 |
2016-02-23 |
Selecta Biosciences, Inc. |
Tolerogenic synthetic nanocarriers
|
US20120283503A1
(en)
|
2011-04-29 |
2012-11-08 |
The Johns Hopkins University |
Nanoparticle loaded stem cells and their use in mri guided hyperthermia
|
US20140056912A1
(en)
|
2011-04-29 |
2014-02-27 |
Novartis Ag |
Methods of treating squamous cell carcinoma
|
ES2957478T3
(es)
|
2011-05-02 |
2024-01-19 |
Univ Wayne State |
Una tecnología de células madre pluripotentes inducidas por proteínas y usos de las mismas
|
UA116189C2
(uk)
|
2011-05-02 |
2018-02-26 |
Мілленніум Фармасьютікалз, Інк. |
КОМПОЗИЦІЯ АНТИ-α4β7 АНТИТІЛА
|
EP2704565B1
(en)
|
2011-05-04 |
2018-08-22 |
The University Of Nottingham |
Novel polymers which resist bacterial attachment
|
US9327029B2
(en)
|
2011-05-05 |
2016-05-03 |
Celacare Technologies, Llc |
Antimicrobial silver hydrogel composition for the treatment of burns and wounds
|
US8945588B2
(en)
|
2011-05-06 |
2015-02-03 |
The University Of Chicago |
Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides
|
CN103547350A
(zh)
|
2011-05-10 |
2014-01-29 |
巴斯夫欧洲公司 |
水包油乳液
|
WO2012153297A1
(en)
|
2011-05-11 |
2012-11-15 |
Ramot At Tel-Aviv University Ltd. |
Targeted polymeric conjugates and uses thereof
|
US20140072657A1
(en)
|
2011-05-12 |
2014-03-13 |
Helmut Vockner |
Novel pharmaceutical formulation
|
WO2012153338A2
(en)
|
2011-05-12 |
2012-11-15 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. |
Liposomes comprising polymer-conjugated lipids and related uses
|
SG194755A1
(en)
|
2011-05-13 |
2013-12-30 |
Novartis Ag |
Pre-fusion rsv f antigens
|
BR112013029490A2
(pt)
|
2011-05-17 |
2019-09-24 |
Moderna Therapeutics Inc |
ácidos nucleicos projetados e métodos de uso dos mesmos para vertebrados não humanos
|
US8691750B2
(en)
|
2011-05-17 |
2014-04-08 |
Axolabs Gmbh |
Lipids and compositions for intracellular delivery of biologically active compounds
|
CN103052757B
(zh)
|
2011-05-20 |
2015-02-25 |
科勒公司 |
马桶安装系统和方法
|
NZ730355A
(en)
|
2011-05-24 |
2022-10-28 |
Tron Translationale Onkologie An Der Univ Der Johannes Gutenberg Univ Mainz Gemeinnuetzige Gmbh |
Individualized vaccines for cancer
|
KR20140024907A
(ko)
|
2011-05-25 |
2014-03-03 |
노파르티스 아게 |
폐암용 바이오마커
|
US20120302940A1
(en)
|
2011-05-26 |
2012-11-29 |
Jackson State University |
Popcorn Shape Gold Nanoparticle For Targeted Diagnosis, Photothermal Treatment and In-Situ Monitoring Therapy Response for Cancer and Multiple Drug Resistance Bacteria
|
US20140308363A1
(en)
|
2011-05-31 |
2014-10-16 |
Bind Therapeutics, Inc. |
Drug loaded polymeric nanoparticles and methods of making and using same
|
WO2013052167A2
(en)
|
2011-06-02 |
2013-04-11 |
The Regents Of The University Of California |
Membrane encapsulated nanoparticles and method of use
|
JP2014516549A
(ja)
|
2011-06-02 |
2014-07-17 |
ノバルティス アーゲー |
ヘッジホッグ阻害剤療法のためのバイオマーカー
|
WO2012168259A1
(en)
|
2011-06-06 |
2012-12-13 |
Novartis Forschungsstiftung, Zweigniederlassung |
Protein tyrosine phosphatase, non-receptor type 11 (ptpn11) and triple-negative breast cancer
|
WO2012170889A1
(en)
|
2011-06-08 |
2012-12-13 |
Shire Human Genetic Therapies, Inc. |
Cleavable lipids
|
ME03491B
(me)
|
2011-06-08 |
2020-01-20 |
Translate Bio Inc |
Kompozicije lipidnih nanočestica i postupci za isporuku irnk
|
WO2012168491A1
(en)
|
2011-06-10 |
2012-12-13 |
Novartis Ag |
Pharmaceutical formulations of pcsk9 antagonists
|
US8636696B2
(en)
|
2011-06-10 |
2014-01-28 |
Kimberly-Clark Worldwide, Inc. |
Transdermal device containing microneedles
|
PE20140576A1
(es)
|
2011-06-10 |
2014-05-24 |
Novartis Ag |
Vacunas bovinas y metodos
|
WO2012170607A2
(en)
|
2011-06-10 |
2012-12-13 |
Novartis Ag |
Use of pcsk9 antagonists
|
US8916696B2
(en)
|
2011-06-12 |
2014-12-23 |
City Of Hope |
Aptamer-mRNA conjugates for targeted protein or peptide expression and methods for their use
|
WO2012172495A1
(en)
|
2011-06-14 |
2012-12-20 |
Novartis Ag |
Compositions and methods for antibodies targeting tem8
|
WO2012172424A1
(en)
|
2011-06-15 |
2012-12-20 |
Crontech Pharma Ab |
Injection needle and device
|
MX2013014789A
(es)
|
2011-06-16 |
2014-01-20 |
Novartis Ag |
Proteinas solubles para utilizarse como productos terapeuticos.
|
EP3199545B1
(en)
|
2011-06-20 |
2019-10-30 |
University of Pittsburgh - Of the Commonwealth System of Higher Education |
Computationally optimized broadly reactive antigens for h1n1 influenza
|
US9862926B2
(en)
|
2011-06-27 |
2018-01-09 |
Cellscript, Llc. |
Inhibition of innate immune response
|
CN103687644B
(zh)
|
2011-06-28 |
2016-11-09 |
艾诺奥医药品有限公司 |
微创性皮肤电穿孔装置
|
PT2726099T
(pt)
|
2011-07-01 |
2018-11-13 |
Novartis Ag |
Método para o tratamento de distúrbios metabólicos
|
US20150024488A1
(en)
|
2011-07-04 |
2015-01-22 |
Commonwealth Scientific And Industrial Research Organisation |
Nucleic acid complex
|
WO2013006837A1
(en)
|
2011-07-06 |
2013-01-10 |
Novartis Ag |
Cationic oil-in-water emulsions
|
CA2840913C
(en)
|
2011-07-06 |
2020-01-21 |
Novartis Ag |
Oil-in-water emulsions that contain nucleic acids
|
EP4115875A1
(en)
|
2011-07-06 |
2023-01-11 |
GlaxoSmithKline Biologicals S.A. |
Liposomes having useful n:p ratio for delivery of rna molecules
|
EP2729168A2
(en)
|
2011-07-06 |
2014-05-14 |
Novartis AG |
Immunogenic compositions and uses thereof
|
US11896636B2
(en)
|
2011-07-06 |
2024-02-13 |
Glaxosmithkline Biologicals Sa |
Immunogenic combination compositions and uses thereof
|
EP2729501A2
(en)
|
2011-07-07 |
2014-05-14 |
Life Technologies Corporation |
Polymer particles, nucleic acid polymer particles and methods of making and using the same
|
WO2013009717A1
(en)
|
2011-07-10 |
2013-01-17 |
Elisabet De Los Pinos |
Virion derived protein nanoparticles for delivering diagnostic or therapeutic agents for the treatment of skin-related diseases
|
WO2013009736A2
(en)
|
2011-07-10 |
2013-01-17 |
President And Fellows Of Harvard College |
Compositions and methods for self-assembly of polymers with complementary macroscopic and microscopic scale units
|
US20130012566A1
(en)
|
2011-07-10 |
2013-01-10 |
Aura Biosciences, Inc. |
Virion Derived Protein Nanoparticles For Delivering Diagnostic Or Therapeutic Agents For The Treatment of Alopecia
|
WO2013012921A2
(en)
|
2011-07-20 |
2013-01-24 |
University Of Iowa Research Foundation |
Nucleic acid aptamers
|
GB2492999A
(en)
|
2011-07-20 |
2013-01-23 |
Univ Central Lancashire |
Neutron detector
|
ES2670944T3
(es)
|
2011-07-21 |
2018-06-04 |
Croda International Plc |
Copolímeros de bloques de poliéter-poliamida ramificados y métodos de preparación y uso de los mismos
|
EP2736921B1
(en)
|
2011-07-25 |
2018-06-27 |
GlaxoSmithKline Biologicals SA |
Compositions and methods for assessing functional immunogenicity of parvovirus vaccines
|
US9493549B2
(en)
|
2011-07-25 |
2016-11-15 |
The Rockefeller University |
Antibodies directed toward the HIV-1 GP120 CD4 binding site with increased potency and breadth
|
US20130028857A1
(en)
|
2011-07-29 |
2013-01-31 |
Selecta Biosciences, Inc. |
Synthetic nanocarriers comprising polymers comprising multiple immunomodulatory agents
|
US9556281B2
(en)
|
2011-08-15 |
2017-01-31 |
The University Of Chicago |
Compositions and methods related to antibodies to staphylococcal protein A
|
BR112014004585A2
(pt)
|
2011-08-26 |
2017-06-13 |
Arrowhead Res Corp |
polímeros de poli(éster vinílico) para liberação de ácido nucleico in vivo
|
US9126966B2
(en)
|
2011-08-31 |
2015-09-08 |
Protiva Biotherapeutics, Inc. |
Cationic lipids and methods of use thereof
|
KR20140067070A
(ko)
|
2011-08-31 |
2014-06-03 |
말린크로트 엘엘씨 |
H-포스포네이트에 의한 나노입자 peg 개질
|
CN103974719A
(zh)
|
2011-08-31 |
2014-08-06 |
诺华股份有限公司 |
用于递送免疫原编码rna的聚乙二醇化脂质体
|
KR20140105433A
(ko)
|
2011-09-01 |
2014-09-01 |
아이알엠 엘엘씨 |
Pdgfr 키나제 억제제로서의 화합물 및 조성물
|
JP2014525435A
(ja)
|
2011-09-02 |
2014-09-29 |
ノバルティス アーゲー |
Hsf1関連疾患を処置するための有機組成物
|
US9464124B2
(en)
|
2011-09-12 |
2016-10-11 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
EP3384938A1
(en)
|
2011-09-12 |
2018-10-10 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
EP2755986A4
(en)
*
|
2011-09-12 |
2015-05-20 |
Moderna Therapeutics Inc |
MODIFIED NUCLEIC ACIDS AND METHODS OF USE
|
TR201909110T4
(tr)
|
2011-09-14 |
2019-07-22 |
Glaxosmithkline Biologicals Sa |
Sakarit-protein glikokonjugatları yapmaya yönelik yöntemler.
|
EA201490636A1
(ru)
|
2011-09-16 |
2014-08-29 |
Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания |
Сконструированные с помощью рнк t-клетки для лечения злокачественных новообразований
|
JP2014531456A
(ja)
|
2011-09-22 |
2014-11-27 |
バインド セラピューティックス インコーポレイテッド |
治療用ナノ粒子と癌を治療する方法
|
US9375388B2
(en)
|
2011-09-23 |
2016-06-28 |
Indian Institute Of Technology, Bombay |
Nanoparticle based cosmetic composition
|
UY34346A
(es)
|
2011-09-26 |
2013-04-30 |
Novartis Ag |
Proteínas de fusión para tratar trastornos metabólicos
|
TW201315742A
(zh)
|
2011-09-26 |
2013-04-16 |
Novartis Ag |
治療代謝病症之雙功能蛋白質
|
WO2013049328A1
(en)
|
2011-09-27 |
2013-04-04 |
Alnylam Pharmaceuticals, Inc. |
Di-aliphatic substituted pegylated lipids
|
WO2013045505A1
(en)
|
2011-09-28 |
2013-04-04 |
Novartis Ag |
Biomarkers for raas combination therapy
|
HUE057725T2
(hu)
*
|
2011-10-03 |
2022-06-28 |
Modernatx Inc |
Módosított nukleozidok, nukleotidok és nukleinsavak és ezek felhasználása
|
WO2013055971A1
(en)
|
2011-10-11 |
2013-04-18 |
Arizona Board Of Regents For And On Behalf Of Arizona State University |
Polymers for delivering a substance into a cell
|
BR112014008694A2
(pt)
|
2011-10-11 |
2017-06-20 |
Novartis Ag |
moléculas de ácido nucleico policistrônico recombinante
|
WO2014066811A1
(en)
|
2012-10-25 |
2014-05-01 |
The Johns Hopkins University |
Bioreducible poly (b-amino ester)s for sirna delivery
|
WO2013055331A1
(en)
|
2011-10-12 |
2013-04-18 |
The Curators Of The University Of Missouri |
Pentablock polymers
|
MX2014004415A
(es)
|
2011-10-14 |
2015-06-05 |
Stc Unm |
Bicapas lipidicas soportadas por nanoparticulas porosas (protecelulas) para suministro dirigido, incluido el suministro transdermico de carga, y los metodos relacionados.
|
ES2769786T3
(es)
|
2011-10-14 |
2020-06-29 |
Recordati Ag |
Anticuerpos y métodos para enfermedades relacionadas con la vía Wnt
|
EP2768571B1
(en)
|
2011-10-18 |
2023-02-22 |
Micell Technologies, Inc. |
Drug delivery medical device
|
KR102011048B1
(ko)
|
2011-10-18 |
2019-08-14 |
다이서나 파마수이티컬, 인크. |
아민 양이온성 지질 및 그것의 용도
|
CA2852857A1
(en)
|
2011-10-20 |
2013-04-25 |
Novartis Ag |
Adjuvanted influenza b virus vaccines for pediatric priming
|
BR112014007485B1
(pt)
|
2011-10-20 |
2022-05-31 |
Novartis Ag |
Métodos para prever responsividade terapêutica de um indivíduo a tratamento com um ativador do receptor de acetilcolina nicotínico alfa 7, e usos do referido ativador
|
JP2015502337A
(ja)
|
2011-10-25 |
2015-01-22 |
ザ ユニバーシティ オブ ブリティッシュ コロンビア |
限界サイズ脂質ナノ粒子および関連方法
|
WO2013061290A1
(en)
|
2011-10-26 |
2013-05-02 |
Nanopass Technologies Ltd. |
Microneedle intradermal drug delivery device with auto-disable functionality
|
JP6151707B2
(ja)
|
2011-10-27 |
2017-06-21 |
マサチューセッツ インスティテュート オブ テクノロジー |
薬物内包微小球の形成が可能なn−末端で官能基化されたアミノ酸誘導体
|
MX343262B
(es)
|
2011-10-27 |
2016-10-28 |
Kimberly Clark Co |
Administración transdérmica de agentes bioactivos de alta viscosidad.
|
CN104023748B
(zh)
|
2011-10-28 |
2018-03-02 |
诚信生物公司 |
含有氨基酸的蛋白质制剂
|
AU2012328457A1
(en)
|
2011-10-28 |
2014-04-24 |
Presage Biosciences, Inc. |
Methods for drug delivery
|
WO2013062140A1
(en)
|
2011-10-28 |
2013-05-02 |
Kyoto University |
Method for efficiently inducing differentiation of pluripotent stem cells into hepatic lineage cells
|
ES2694154T3
(es)
|
2011-10-31 |
2018-12-18 |
Mallinckrodt Llc |
Composiciones de liposomas combinatorias para el tratamiento del cáncer
|
EP3091029B1
(en)
|
2011-10-31 |
2022-12-28 |
F. Hoffmann-La Roche AG |
Anti-il13 antibody formulations
|
RS58562B1
(sr)
|
2011-11-04 |
2019-05-31 |
Nitto Denko Corp |
Postupak za sterilnu proizvodnju čestica lipid-nukleinska kiselina
|
JP6143269B2
(ja)
|
2011-11-04 |
2017-06-07 |
エージェンシー フォー サイエンス,テクノロジー アンド リサーチ |
自己組織化複合超小型ペプチドポリマーヒドロゲル
|
WO2013067355A1
(en)
|
2011-11-04 |
2013-05-10 |
Novartis Ag |
Low density lipoprotein-related protein 6 (lrp6) - half life extender constructs
|
US9579338B2
(en)
|
2011-11-04 |
2017-02-28 |
Nitto Denko Corporation |
Method of producing lipid nanoparticles for drug delivery
|
WO2013067537A1
(en)
|
2011-11-04 |
2013-05-10 |
Univertiy Of Notre Dame Du Lac |
Nanoparticle-based drug delivery
|
US20130115247A1
(en)
|
2011-11-05 |
2013-05-09 |
Aura Biosciences, Inc. |
Virion Derived Protein Nanoparticles For Delivering Radioisotopes For The Diagnosis And Treatment Of Malignant And Systemic Disease And The Monitoring Of Therapy
|
US20130116408A1
(en)
|
2011-11-05 |
2013-05-09 |
Aura Biosciences, Inc. |
Virion Derived Protein Nanoparticles For Delivering Radioisotopes For The Diagnosis And Treatment Of Malignant And Systemic Disease And The Monitoring Of Therapy
|
EP2776022A1
(en)
|
2011-11-08 |
2014-09-17 |
Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute For Biomedical Research |
New treatment for neurodegenerative diseases
|
US20140294732A1
(en)
|
2011-11-08 |
2014-10-02 |
Novartis Forschungsstiftung, Zweigniederlassung, Friedrich Miescher Institute |
Early diagnostic of neurodegenerative diseases
|
US20140287510A1
(en)
|
2011-11-08 |
2014-09-25 |
Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute |
Rod cell-specific promoter
|
EP2776013B8
(en)
|
2011-11-08 |
2023-08-30 |
The Board of Trustees of the University of Arkansas |
Methods and compositions for x-ray induced release from ph sensitive liposomes
|
US9581590B2
(en)
|
2011-11-09 |
2017-02-28 |
Board Of Trustees Of Michigan State University |
Metallic nanoparticle synthesis with carbohydrate capping agent
|
CA3166278A1
(en)
|
2011-11-11 |
2013-05-16 |
Variation Biotechnologies Inc. |
Compositions and methods for treatment of cytomegalovirus
|
WO2013071047A1
(en)
|
2011-11-11 |
2013-05-16 |
Children's Medical Center Corporation |
Compositions and methods for in vitro transcription of rna
|
EP2780035A1
(en)
|
2011-11-14 |
2014-09-24 |
Novartis AG |
Immunogenic complexes of polyanionic carbomers and env polypeptides and methods of manufacture and use thereof
|
CA2855619A1
(en)
|
2011-11-15 |
2013-05-23 |
Novartis Ag |
Combination of a phosphoinositide 3-kinase inhibitor and a modulator of the janus kinase 2 - signal transducer and activator of transcription 5 pathway
|
PT3384903T
(pt)
|
2011-11-18 |
2020-06-25 |
Regeneron Pharma |
Micropartícula contendo proteína terapêutica revestida com polímero biodegradável para uso médico
|
WO2013077907A1
(en)
|
2011-11-21 |
2013-05-30 |
Novartis Ag |
Methods of treating psoriatic arthritis (psa) using il-17 antagonists and psa response or non- response alleles
|
WO2013078199A2
(en)
|
2011-11-23 |
2013-05-30 |
Children's Medical Center Corporation |
Methods for enhanced in vivo delivery of synthetic, modified rnas
|
TR201111743A2
(tr)
|
2011-11-28 |
2012-04-24 |
Nesl�Han G�Rsoy Reyhan |
Kanser tedavisinde kullanılmak üzere yağ bazlı nanotaşıyıcı sistemler.
|
WO2013082111A2
(en)
|
2011-11-29 |
2013-06-06 |
The University Of North Carolina At Chapel Hill |
Geometrically engineered particles and methods for modulating macrophage or immune responses
|
US9364549B2
(en)
|
2011-11-30 |
2016-06-14 |
Andreas Voigt |
Hydrophobic drug-delivery material, method for manufacturing thereof and methods for delivery of a drug-delivery composition
|
CA2857502C
(en)
|
2011-11-30 |
2019-08-13 |
3M Innovative Properties Company |
Microneedle device including a peptide therapeutic agent and an amino acid and methods of making and using the same
|
JP2015500241A
(ja)
|
2011-12-02 |
2015-01-05 |
ペガサス ラボラトリーズ インコーポレイテッド |
両親媒性脂質をベースとする徐放性組成物
|
WO2013082529A1
(en)
|
2011-12-02 |
2013-06-06 |
Yale University |
Enzymatic synthesis of poly(amine-co-esters) and methods of use thereof for gene delivery
|
US20130142781A1
(en)
|
2011-12-02 |
2013-06-06 |
Invivo Therapeutics Corporation |
Peg based hydrogel for peripheral nerve injury applications and compositions and method of use of synthetic hydrogel sealants
|
EP2788439A4
(en)
|
2011-12-05 |
2015-09-02 |
Nano Prec Medical Inc |
DEVICE HAVING A MEMBRANE FOR TITANIUM DIOXIDE NANOTUBE FOR DRUG DELIVERY
|
EP2788033B1
(en)
|
2011-12-05 |
2017-05-31 |
Factor Bioscience Inc. |
Methods and products for transfecting cells
|
US8497124B2
(en)
|
2011-12-05 |
2013-07-30 |
Factor Bioscience Inc. |
Methods and products for reprogramming cells to a less differentiated state
|
GB201121070D0
(en)
|
2011-12-07 |
2012-01-18 |
Isis Innovation |
composition for delivery of biotherapeutics
|
HUE21212055T1
(hu)
|
2011-12-07 |
2022-11-28 |
Alnylam Pharmaceuticals Inc |
Biológiailag lebontható lipidek hatóanyagok bejuttatására
|
WO2013086373A1
(en)
|
2011-12-07 |
2013-06-13 |
Alnylam Pharmaceuticals, Inc. |
Lipids for the delivery of active agents
|
EP2788316B1
(en)
|
2011-12-07 |
2019-04-24 |
Alnylam Pharmaceuticals, Inc. |
Branched alkyl and cycloalkyl terminated biodegradable lipids for the delivery of active agents
|
US10087422B2
(en)
|
2011-12-09 |
2018-10-02 |
President And Fellows Of Harvard College |
Organ chips and uses thereof
|
EP2787977A4
(en)
|
2011-12-09 |
2015-05-06 |
Univ California |
LIPOSOMAL ACTIVE INVERTING
|
US9725687B2
(en)
|
2011-12-09 |
2017-08-08 |
President And Fellows Of Harvard College |
Integrated human organ-on-chip microphysiological systems
|
US20140045913A1
(en)
|
2011-12-12 |
2014-02-13 |
Kyowa Hakko Kirin Co., Ltd. |
Lipid nano particles comprising combination of cationic lipid
|
JP6182457B2
(ja)
|
2011-12-12 |
2017-08-16 |
協和発酵キリン株式会社 |
カチオン性脂質を含有するドラックデリバリーシステムのための脂質ナノ粒子
|
KR20140116095A
(ko)
|
2011-12-12 |
2014-10-01 |
더 트러스티스 오브 더 유니버시티 오브 펜실바니아 |
Mrsa pbp2a 및 이의 단편들을 포함하는 단백질, 이를 인코딩한 핵산, 및 mrsa 감염을 예방 및 치료하기 위한 조성물 및 그의 용도
|
US20150000936A1
(en)
|
2011-12-13 |
2015-01-01 |
Schlumberger Technology Corporation |
Energization of an element with a thermally expandable material
|
EP2604253A1
(en)
|
2011-12-13 |
2013-06-19 |
Otto Glatter |
Water-in-oil emulsions and methods for their preparation
|
KR102046042B1
(ko)
|
2011-12-13 |
2019-11-18 |
엔진아이씨 몰레큘러 딜리버리 피티와이 리미티드 |
뇌종양에 대한 치료제의 전달을 위한 박테리아 유래된, 무손상 미니세포
|
EP2791159A4
(en)
|
2011-12-14 |
2015-10-14 |
Moderna Therapeutics Inc |
MODIFIED NUCLEIC ACIDS, AND SHORT-TERM CARE USES THEREOF
|
US20140378538A1
(en)
|
2011-12-14 |
2014-12-25 |
Moderma Therapeutics, Inc. |
Methods of responding to a biothreat
|
WO2013090897A1
(en)
|
2011-12-15 |
2013-06-20 |
The Trustees Of The University Of Pennsylvania |
Using adaptive immunity to detect drug resistance
|
US9636414B2
(en)
|
2011-12-15 |
2017-05-02 |
Biontech Ag |
Particles comprising single stranded RNA and double stranded RNA for immunomodulation
|
WO2013090601A2
(en)
|
2011-12-16 |
2013-06-20 |
Massachusetts Institute Of Technology |
Compact nanoparticles for biological applications
|
US20130157963A1
(en)
|
2011-12-16 |
2013-06-20 |
Allergan, Inc. |
Ophthalmic compositions comprising polyvinyl capralactam-polyvinyl acetate-polyethylene glycol graft copolymers
|
CN104245794A
(zh)
|
2011-12-16 |
2014-12-24 |
麻省理工学院 |
α-氨基脒聚合物及其用途
|
HRP20220717T1
(hr)
|
2011-12-16 |
2022-07-22 |
Modernatx, Inc. |
Modificirani pripravci mrna
|
EP2791172B1
(en)
|
2011-12-16 |
2017-07-19 |
Synthon Biopharmaceuticals B.V. |
Compounds and methods for treating inflammatory diseases
|
KR20140103939A
(ko)
|
2011-12-16 |
2014-08-27 |
노파르티스 아게 |
흡입 프로파일-비의존적 약물 전달을 위한 에어로졸화 장치
|
US9546235B2
(en)
|
2011-12-19 |
2017-01-17 |
The University Of Sydney |
Peptide-hydrogel composite
|
US9241829B2
(en)
|
2011-12-20 |
2016-01-26 |
Abbott Medical Optics Inc. |
Implantable intraocular drug delivery apparatus, system and method
|
JP2015510495A
(ja)
|
2011-12-21 |
2015-04-09 |
モデルナ セラピューティクス インコーポレイテッドModerna Therapeutics,Inc. |
器官または器官移植片の生存可能性または寿命を延長する方法
|
US20130195851A1
(en)
|
2011-12-23 |
2013-08-01 |
Genentech, Inc. |
Articles of manufacture and methods for co-administration of antibodies
|
US10814115B2
(en)
|
2011-12-27 |
2020-10-27 |
Massachusetts Institute Of Technology |
Microneedle devices and uses thereof
|
WO2013101690A1
(en)
|
2011-12-29 |
2013-07-04 |
modeRNA Therapeutics |
Modified mrnas encoding cell-penetrating polypeptides
|
JP2015505309A
(ja)
|
2011-12-29 |
2015-02-19 |
ノバルティス アーゲー |
髄膜炎菌h因子結合タンパク質のアジュバントされた組み合わせ
|
SI3421601T1
(sl)
|
2011-12-30 |
2020-03-31 |
Cellscript, Llc |
Izdelava in uporaba in vitro-sintetizirane ssRNA za uvajanje v celice sesalca, da se inducira biološki ali biokemijski učinek
|
CN104136023A
(zh)
|
2012-01-06 |
2014-11-05 |
密执安生命治疗有限责任公司 |
降低心血管疾病风险的方法
|
US20150030576A1
(en)
|
2012-01-10 |
2015-01-29 |
Moderna Therapeutics, Inc. |
Methods and compositions for targeting agents into and across the blood-brain barrier
|
AU2013212066B2
(en)
|
2012-01-26 |
2018-11-08 |
Life Technologies Corporation |
Methods for increasing the infectivity of viruses
|
SG11201404361UA
(en)
|
2012-01-26 |
2014-09-26 |
Life Technologies Corp |
Methods for increasing the infectivity of viruses
|
WO2013113325A1
(en)
|
2012-01-31 |
2013-08-08 |
Curevac Gmbh |
Negatively charged nucleic acid comprising complexes for immunostimulation
|
EP2623121A1
(en)
|
2012-01-31 |
2013-08-07 |
Bayer Innovation GmbH |
Pharmaceutical composition comprising a polymeric carrier cargo complex and an antigen
|
WO2013113326A1
(en)
|
2012-01-31 |
2013-08-08 |
Curevac Gmbh |
Pharmaceutical composition comprising a polymeric carrier cargo complex and at least one protein or peptide antigen
|
CN106883334B
(zh)
|
2012-02-09 |
2019-06-18 |
生命技术公司 |
亲水性聚合物颗粒及其制备方法
|
EP3597209A1
(en)
|
2012-02-22 |
2020-01-22 |
Northwestern University |
Nanostructures for treating cancers and other conditions
|
EP2817345A1
(en)
|
2012-02-22 |
2014-12-31 |
Cerulean Pharma Inc. |
Conjugates, particles, compositions, and related methods
|
US20130243867A1
(en)
|
2012-02-23 |
2013-09-19 |
University Of South Florida (A Florida Non-Profit Corporation) |
Micelle compositions and methods for their use
|
US20130224268A1
(en)
|
2012-02-27 |
2013-08-29 |
Newgen Biopharma Corp. |
Topical delivery of hormonal and non hormonal nano formulations, methods of making and using the same
|
EP2819652A1
(en)
|
2012-02-27 |
2015-01-07 |
Epitarget As |
Use of a particulate immunomodulator in cancer therapy
|
EP2819651A1
(en)
|
2012-02-27 |
2015-01-07 |
Epitarget AS |
Use of an antibody and a particulate immunomodulator in therapy
|
US20150037334A1
(en)
|
2012-03-01 |
2015-02-05 |
Amgen Research (Munich) Gmbh |
Long life polypeptide binding molecules
|
US20130236504A1
(en)
|
2012-03-06 |
2013-09-12 |
Medical University Of South Carolina |
Delivery System for Enhancing Drug Efficacy
|
CN104271149B
(zh)
|
2012-03-13 |
2016-03-16 |
夸祖鲁-纳塔尔大学 |
经皮递送装置
|
US10322089B2
(en)
|
2012-03-14 |
2019-06-18 |
The Board Of Trustees Of The Leland Stanford Junior University |
Nanoparticles, nanoparticle delivery methods, and systems of delivery
|
US8962577B2
(en)
|
2012-03-16 |
2015-02-24 |
The Johns Hopkins University |
Controlled release formulations for the delivery of HIF-1 inhibitors
|
AU2013231638B2
(en)
|
2012-03-16 |
2017-10-12 |
Merck Patent Gmbh |
Targeting aminoacid lipids
|
JP6138904B2
(ja)
|
2012-03-16 |
2017-05-31 |
ザ・ジョンズ・ホプキンス・ユニバーシティー |
活性剤の送達のための非線状マルチブロックコポリマー薬物コンジュゲート
|
WO2013142349A1
(en)
|
2012-03-23 |
2013-09-26 |
University Of Chicago |
Compositions and methods related to staphylococcal sbi
|
US9610346B2
(en)
|
2012-03-23 |
2017-04-04 |
International Aids Vaccine Initiative |
Recombinant viral vectors
|
US9717685B2
(en)
|
2012-03-26 |
2017-08-01 |
President And Fellows Of Harvard College |
Lipid-coated nucleic acid nanostructures of defined shape
|
WO2013143555A1
(en)
|
2012-03-26 |
2013-10-03 |
Biontech Ag |
Rna formulation for immunotherapy
|
CA2866955A1
(en)
|
2012-03-27 |
2013-10-03 |
Curevac Gmbh |
Artificial nucleic acid molecules
|
EP2830594B1
(en)
|
2012-03-27 |
2018-05-09 |
Sirna Therapeutics, Inc. |
DIETHER BASED BIODEGRADABLE CATIONIC LIPIDS FOR siRNA DELIVERY
|
CA2859452C
(en)
|
2012-03-27 |
2021-12-21 |
Curevac Gmbh |
Artificial nucleic acid molecules for improved protein or peptide expression
|
CN108929880A
(zh)
|
2012-03-27 |
2018-12-04 |
库瑞瓦格股份公司 |
包含5′toputr的人工核酸分子
|
ES2858523T3
(es)
|
2012-03-29 |
2021-09-30 |
Translate Bio Inc |
Nanopartículas neutras derivadas de lípidos
|
AU2013243947A1
(en)
|
2012-04-02 |
2014-10-30 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of proteins
|
US10501512B2
(en)
|
2012-04-02 |
2019-12-10 |
Modernatx, Inc. |
Modified polynucleotides
|
US20150050354A1
(en)
|
2012-04-02 |
2015-02-19 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the treatment of otic diseases and conditions
|
CA2868391A1
(en)
|
2012-04-02 |
2013-10-10 |
Stephane Bancel |
Polynucleotides comprising n1-methyl-pseudouridine and methods for preparing the same
|
US20140275229A1
(en)
|
2012-04-02 |
2014-09-18 |
Moderna Therapeutics, Inc. |
Modified polynucleotides encoding udp glucuronosyltransferase 1 family, polypeptide a1
|
EP2833918B1
(en)
|
2012-04-05 |
2019-05-08 |
Massachusetts Institute of Technology |
Immunostimulatory compositions and methods of use thereof
|
WO2013151650A1
(en)
|
2012-04-05 |
2013-10-10 |
University Of Florida Research Foundation, Inc. |
Neurophilic nanoparticles
|
WO2013152351A2
(en)
|
2012-04-06 |
2013-10-10 |
The Trustees Of Columbia University In The City Of New York |
Fusion polypeptides and methods of use thereof
|
DK2836200T3
(da)
|
2012-04-08 |
2020-09-21 |
Urogen Pharma Ltd |
Termoreversible hydrogelpræparater til anvendelse i behandlingen af lidelser i urothelium
|
ES2560235T3
(es)
|
2012-04-11 |
2016-02-18 |
Intezyne Technologies Inc. |
Copolímeros en bloque para micelas estables
|
US9603800B2
(en)
|
2012-04-12 |
2017-03-28 |
Yale University |
Methods of treating inflammatory and autoimmune diseases and disorders using nanolipogels
|
WO2013154766A1
(en)
|
2012-04-13 |
2013-10-17 |
New York University |
Microrna control of ldl receptor pathway
|
WO2013155513A1
(en)
|
2012-04-13 |
2013-10-17 |
President And Fellows Of Harvard College |
Devices and methods for in vitro aerosol delivery
|
KR20150001710A
(ko)
|
2012-04-18 |
2015-01-06 |
애로우헤드 리서치 코오포레이션 |
In Vivo 핵산 전달용 폴리(아크릴레이트) 고분자
|
EP2838877B1
(en)
|
2012-04-19 |
2018-09-12 |
Sirna Therapeutics, Inc. |
Novel diester and triester based low molecular weight, biodegradable cationic lipids for oligonucleotide delivery
|
WO2013163234A1
(en)
|
2012-04-23 |
2013-10-31 |
Massachusetts Institute Of Technology |
Stable layer-by-layer coated particles
|
EP2841579B1
(en)
|
2012-04-25 |
2018-10-10 |
Regulus Therapeutics Inc. |
Microrna compounds and methods for modulating mir-21 activity
|
KR102310775B1
(ko)
|
2012-05-03 |
2021-10-07 |
칼라 파마슈티컬스, 인크. |
개선된 점막 수송을 나타내는 제약 나노입자
|
EP2849728A1
(en)
|
2012-05-04 |
2015-03-25 |
The Johns Hopkins University |
Lipid-based drug carriers for rapid penetration through mucus linings
|
US20150087671A1
(en)
|
2012-05-16 |
2015-03-26 |
Micell Technologies, Inc. |
Low burst sustained release lipophilic and biologic agent compositions
|
WO2013173582A1
(en)
|
2012-05-17 |
2013-11-21 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Hepatitis c virus neutralizing antibody
|
WO2013173693A1
(en)
|
2012-05-18 |
2013-11-21 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Nanoparticles with enhanced entry into cancer cells
|
JP6228191B2
(ja)
|
2012-05-23 |
2017-11-08 |
ジ・オハイオ・ステート・ユニバーシティ |
脂質コートされたアルブミンナノ粒子組成物と、それを作製する方法、及びそれを使用する方法
|
US20150306249A1
(en)
|
2012-05-25 |
2015-10-29 |
Curevac Gmbh |
Reversible immobilization and/or controlled release of nucleic acid containing nanoparticles by (biodegradable) polymer coatings
|
ES2811798T3
(es)
|
2012-06-06 |
2021-03-15 |
Loma Vista Medical Inc |
Dispositivos médicos inflables
|
WO2013185069A1
(en)
|
2012-06-08 |
2013-12-12 |
Shire Human Genetic Therapies, Inc. |
Pulmonary delivery of mrna to non-lung target cells
|
DK3489220T3
(da)
|
2012-06-08 |
2021-09-06 |
Nitto Denko Corp |
Lipider til terapeutisk middel-leveringsformuleringer
|
DK2858677T3
(da)
|
2012-06-08 |
2020-08-31 |
Ethris Gmbh |
Pulmonær levering af messenger rna
|
WO2014014613A2
(en)
|
2012-06-20 |
2014-01-23 |
President And Fellows Of Harvard College |
Self-assembling peptides, peptide nanostructures and uses thereof
|
US20140005379A1
(en)
|
2012-06-20 |
2014-01-02 |
Frank GU |
Nanoparticle delivery system and components thereof
|
EP2866833B1
(en)
|
2012-06-27 |
2019-05-15 |
Merck Sharp & Dohme Corp. |
Crystalline anti-human il-23 antibodies
|
US9150841B2
(en)
|
2012-06-29 |
2015-10-06 |
Shire Human Genetic Therapies, Inc. |
Cells for producing recombinant iduronate-2-sulfatase
|
US9956291B2
(en)
|
2012-07-10 |
2018-05-01 |
Shaker A. Mousa |
Nanoformulation and methods of use of thyroid receptor beta1 agonists for liver targeting
|
EP2872120B1
(en)
|
2012-07-16 |
2017-05-03 |
Nanoderm Sciences, Inc. |
Therapeutic nanoparticles with a polymyxin b as targeting agent
|
EP2687252A1
(en)
|
2012-07-17 |
2014-01-22 |
Sanofi-Aventis Deutschland GmbH |
Drug delivery device
|
EP2687251A1
(en)
|
2012-07-17 |
2014-01-22 |
Sanofi-Aventis Deutschland GmbH |
Drug delivery device
|
CN103566377A
(zh)
|
2012-07-18 |
2014-02-12 |
上海博笛生物科技有限公司 |
癌症的靶向免疫治疗
|
WO2014015334A1
(en)
|
2012-07-20 |
2014-01-23 |
Brown University |
System and methods for nanostructure protected delivery of treatment agent and selective release thereof
|
EP2877600B1
(en)
|
2012-07-24 |
2019-04-10 |
President and Fellows of Harvard College |
Self-assembly of nucleic acid nanostructures
|
GB201213624D0
(en)
|
2012-07-27 |
2012-09-12 |
Univ Ulster The |
Method and system for production of conjugated nanoparticles
|
WO2014015422A1
(en)
|
2012-07-27 |
2014-01-30 |
Ontario Institute For Cancer Research |
Cellulose-based nanoparticles for drug delivery
|
WO2014025795A1
(en)
|
2012-08-07 |
2014-02-13 |
Northeastern University |
Compositions for the delivery of rna and drugs into cells
|
WO2014024193A1
(en)
|
2012-08-07 |
2014-02-13 |
Prodel Pharma Ltd. |
Compositions and methods for rapid transmucosal delivery of pharmaceutical ingredients
|
CN104582747B
(zh)
|
2012-08-08 |
2016-12-21 |
南洋理工大学 |
用于制造具有活细胞的水凝胶微粒的方法和用于制造组织工程支架的组合物
|
US20140155861A1
(en)
|
2012-08-08 |
2014-06-05 |
Presage Biosciences, Inc. |
Extrusion methods and devices for drug delivery
|
CA2881440C
(en)
|
2012-08-10 |
2022-05-17 |
University Of North Texas Health Science Center |
Drug delivery vehicle comprising conjugates between targeting polyamino acids and fatty acids
|
WO2014027006A1
(en)
|
2012-08-13 |
2014-02-20 |
Edko Pazarlama Tanitim Ticaret Limited Sirketi |
Bioadhesive formulations for use in drug delivery
|
WO2014028487A1
(en)
|
2012-08-13 |
2014-02-20 |
Massachusetts Institute Of Technology |
Amine-containing lipidoids and uses thereof
|
WO2014028429A2
(en)
|
2012-08-14 |
2014-02-20 |
Moderna Therapeutics, Inc. |
Enzymes and polymerases for the synthesis of rna
|
US9827321B2
(en)
|
2012-08-14 |
2017-11-28 |
The Trustees Of The University Of Pennsylvania |
Stabilizing shear-thinning hydrogels
|
WO2014026284A1
(en)
|
2012-08-14 |
2014-02-20 |
Froese Aaron |
Internal structured self assembling liposomes
|
EP2885414B1
(en)
|
2012-08-15 |
2020-09-23 |
The University of Chicago |
Exosome-based therapeutics against neurodegenerative disorders
|
WO2014039185A1
(en)
|
2012-09-05 |
2014-03-13 |
Creighton University |
Polymeric nanoparticles in a thermosensitive gel for coital-independent vaginal prophylaxis of hiv
|
US8703197B2
(en)
|
2012-09-13 |
2014-04-22 |
International Business Machines Corporation |
Branched polyamines for delivery of biologically active materials
|
EP2895156B1
(en)
|
2012-09-17 |
2019-05-08 |
Pfizer Inc. |
Process for preparing therapeutic nanoparticles
|
WO2014047649A1
(en)
|
2012-09-24 |
2014-03-27 |
The Regents Of The University Of California |
Methods for arranging and packing nucleic acids for unusual resistance to nucleases and targeted delivery for gene therapy
|
WO2014052634A1
(en)
|
2012-09-27 |
2014-04-03 |
The University Of North Carolina At Chapel Hill |
Lipid coated nanoparticles containing agents having low aqueous and lipid solubilities and methods thereof
|
US20150307542A1
(en)
|
2012-10-03 |
2015-10-29 |
Moderna Therapeutics, Inc. |
Modified nucleic acid molecules and uses thereof
|
US20140100178A1
(en)
|
2012-10-04 |
2014-04-10 |
Aslam Ansari |
Composition and methods for site-specific drug delivery to treat malaria and other liver diseases
|
WO2014053880A1
(en)
|
2012-10-04 |
2014-04-10 |
Centre National De La Recherche Scientifique |
Cell penetrating peptides for intracellular delivery of molecules
|
WO2014053881A1
(en)
|
2012-10-04 |
2014-04-10 |
Centre National De La Recherche Scientifique |
Cell penetrating peptides for intracellular delivery of molecules
|
WO2014053882A1
(en)
|
2012-10-04 |
2014-04-10 |
Centre National De La Recherche Scientifique |
Cell penetrating peptides for intracellular delivery of molecules
|
EP2716655A1
(en)
|
2012-10-04 |
2014-04-09 |
Institut Pasteur |
Neutralizing antibodies directed against Hepatitis C virus ectodomain glycoprotein E2
|
EP2903595A1
(en)
|
2012-10-04 |
2015-08-12 |
University Of The Witwatersrand, Johannesburg |
Liposomal drug delivery system
|
WO2014053879A1
(en)
|
2012-10-04 |
2014-04-10 |
Centre National De La Recherche Scientifique |
Cell penetrating peptides for intracellular delivery of molecules
|
EP2716689A1
(en)
|
2012-10-05 |
2014-04-09 |
National University of Ireland, Galway |
Polymer comprising a plurality of branches having at least one disulfide group and/or at least one vinyl group
|
WO2014064534A2
(en)
|
2012-10-05 |
2014-05-01 |
Chrontech Pharma Ab |
Injection needle, device, immunogenic compositions and method of use
|
WO2014059022A1
(en)
|
2012-10-09 |
2014-04-17 |
The Brigham And Women's Hospital, Inc. |
Nanoparticles for targeted delivery of multiple therapeutic agents and methods of use
|
US20140106260A1
(en)
|
2012-10-11 |
2014-04-17 |
The Trustees Of The University Of Pennsylvania |
Core-shell nanoparticulate compositions and methods
|
EP2908818A4
(en)
|
2012-10-16 |
2016-07-13 |
Endocyte Inc |
CONJUGATES OF DRUG DELIVERY CONTAINING ARTIFICIAL AMINO ACIDS AND METHODS OF USE
|
ES2822135T3
(es)
|
2012-10-18 |
2021-04-29 |
Univ Rockefeller |
Anticuerpos anti-VIH ampliamente neutralizantes
|
CN104918639B
(zh)
|
2012-10-22 |
2018-01-26 |
萨拜格Rfa公司 |
用于将治疗剂递送到活细胞和细胞核中的系统
|
KR20150090072A
(ko)
*
|
2012-10-23 |
2015-08-05 |
카리스 라이프 사이언스 스위스 홀딩스 게엠베하 |
압타머 및 이의 용도
|
US20150272900A1
(en)
|
2012-10-26 |
2015-10-01 |
The Johns Hopkins University |
Layer-By-Layer Approach to Co-Deliver DNA and siRNA via AuNPs: A Potential Platform for Modifying Release Kinetics
|
US20140315795A1
(en)
|
2012-10-26 |
2014-10-23 |
Nlife Therapeutics, S.L. |
Compositions and Methods for Selective Delivery of Oligonucleotide Molecules to Cell Types
|
US10172956B2
(en)
|
2012-10-26 |
2019-01-08 |
Vanderbilt University |
Polymeric nanoparticles
|
US20150376581A1
(en)
|
2012-10-29 |
2015-12-31 |
Technische Universitaet Dortmund |
T7 rna polymerase variants and methods of using the same
|
JP6510416B2
(ja)
|
2012-11-01 |
2019-05-08 |
ファクター バイオサイエンス インコーポレイテッド |
細胞中でタンパク質を発現するための方法および生成物
|
WO2014071072A2
(en)
|
2012-11-02 |
2014-05-08 |
Pungente Michael D |
Novel cationic carotenoid-based lipids for cellular nucleic acid uptake
|
EP2914723B1
(en)
|
2012-11-05 |
2018-06-13 |
Fondazione Centro San Raffaele |
Novel targets in multiple myeloma and other disorders
|
US8852648B2
(en)
|
2012-11-06 |
2014-10-07 |
Rochal Industries, Llp |
Delivery of biologically-active agents using volatile, hydrophobic solvents
|
US9975916B2
(en)
|
2012-11-06 |
2018-05-22 |
President And Fellows Of Harvard College |
Compositions and methods relating to complex nucleic acid nanostructures
|
EP2916873B1
(en)
|
2012-11-07 |
2017-07-26 |
Council of Scientific & Industrial Research |
Nanocomplex containing amphipathic peptide useful for efficient transfection of biomolecules
|
US9572893B2
(en)
|
2012-11-07 |
2017-02-21 |
Council Of Scientific And Industrial Research |
Nanocomplex containing cationic peptide for biomolecule delivery
|
EP2917233A1
(en)
|
2012-11-08 |
2015-09-16 |
Novozymes Biopharma DK A/S |
Albumin variants
|
MX2015005839A
(es)
|
2012-11-08 |
2015-12-17 |
Clearside Biomedical Inc |
Metodos y dispositivos para el tratamiento de trastornos oculares en sujetos humanos.
|
MX2015005831A
(es)
|
2012-11-08 |
2015-09-24 |
Eleven Biotherapeutics Inc |
Antagonistas de il-6 y usos de los mismos.
|
TW201920677A
(zh)
|
2012-11-08 |
2019-06-01 |
美商武田疫苗股份有限公司 |
登革熱病毒血清型4型之建構物的組成物、方法及用途
|
US9200119B2
(en)
|
2012-11-09 |
2015-12-01 |
Momentive Performance Materials Inc. |
Silicon-containing zwitterionic linear copolymer composition
|
EP2916853B1
(en)
|
2012-11-09 |
2020-05-06 |
Velin-Pharma A/S |
Compositions for pulmonary delivery
|
WO2014071963A1
(en)
|
2012-11-09 |
2014-05-15 |
Biontech Ag |
Method for cellular rna expression
|
AU2013343864B2
(en)
|
2012-11-09 |
2019-04-04 |
BioNTech SE |
Method for cellular RNA expression
|
WO2014074218A1
(en)
|
2012-11-12 |
2014-05-15 |
Redwood Bioscience, Inc. |
Compounds and methods for producing a conjugate
|
GB201220354D0
(en)
|
2012-11-12 |
2012-12-26 |
Medpharm Ltd |
Dermal compositions
|
WO2014075047A2
(en)
|
2012-11-12 |
2014-05-15 |
Genvec, Inc. |
Malaria antigens and methods of use
|
US9943608B2
(en)
|
2012-11-13 |
2018-04-17 |
Baylor College Of Medicine |
Multi-arm biodegradable polymers for nucleic acid delivery
|
WO2014078636A1
(en)
|
2012-11-16 |
2014-05-22 |
President And Fellows Of Harvard College |
Nucleic acid hydrogel self-assembly
|
US9310374B2
(en)
|
2012-11-16 |
2016-04-12 |
Redwood Bioscience, Inc. |
Hydrazinyl-indole compounds and methods for producing a conjugate
|
WO2014076709A1
(en)
|
2012-11-19 |
2014-05-22 |
Technion Research And Development Foundation Ltd. |
Liposomes for in-vivo delivery
|
EP2732825B1
(en)
|
2012-11-19 |
2015-07-01 |
Invivogen |
Conjugates of a TLR7 and/or TLR8 agonist and a TLR2 agonist
|
US20140141037A1
(en)
|
2012-11-20 |
2014-05-22 |
Novartis Ag |
Rsv f prefusion trimers
|
US20150290328A1
(en)
|
2012-11-20 |
2015-10-15 |
Phasebio Pharmaceuticals, Inc. |
Formulations of active agents for sustained release
|
WO2014081303A1
(en)
|
2012-11-22 |
2014-05-30 |
Tagworks Pharmaceuticals B.V. |
Chemically cleavable group
|
WO2014081300A1
(en)
|
2012-11-22 |
2014-05-30 |
Tagworks Pharmaceuticals B.V. |
Channel protein activatable liposomes
|
WO2014081299A1
(en)
|
2012-11-22 |
2014-05-30 |
Tagworks Pharmaceuticals B.V. |
Activatable liposomes
|
ES2921623T3
(es)
|
2012-11-26 |
2022-08-30 |
Modernatx Inc |
ARN modificado terminalmente
|
WO2014093574A1
(en)
|
2012-12-13 |
2014-06-19 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for altering cell phenotype
|
WO2014108515A1
(en)
|
2013-01-10 |
2014-07-17 |
Novartis Ag |
Influenza virus immunogenic compositions and uses thereof
|
US20140200261A1
(en)
|
2013-01-17 |
2014-07-17 |
Moderna Therapeutics, Inc. |
Signal-sensor polynucleotides for the alteration of cellular phenotypes
|
US20160022840A1
(en)
|
2013-03-09 |
2016-01-28 |
Moderna Therapeutics, Inc. |
Heterologous untranslated regions for mrna
|
EP2968397A4
(en)
|
2013-03-12 |
2016-12-28 |
Moderna Therapeutics Inc |
DIAGNOSIS AND TREATMENT OF FIBROSIS
|
WO2014159813A1
(en)
|
2013-03-13 |
2014-10-02 |
Moderna Therapeutics, Inc. |
Long-lived polynucleotide molecules
|
EP2971010B1
(en)
|
2013-03-14 |
2020-06-10 |
ModernaTX, Inc. |
Formulation and delivery of modified nucleoside, nucleotide, and nucleic acid compositions
|
WO2014152030A1
(en)
|
2013-03-15 |
2014-09-25 |
Moderna Therapeutics, Inc. |
Removal of dna fragments in mrna production process
|
WO2014144767A1
(en)
|
2013-03-15 |
2014-09-18 |
Moderna Therapeutics, Inc. |
Ion exchange purification of mrna
|
WO2014152027A1
(en)
|
2013-03-15 |
2014-09-25 |
Moderna Therapeutics, Inc. |
Manufacturing methods for production of rna transcripts
|
WO2014152031A1
(en)
|
2013-03-15 |
2014-09-25 |
Moderna Therapeutics, Inc. |
Ribonucleic acid purification
|
US20160017313A1
(en)
|
2013-03-15 |
2016-01-21 |
Moderna Therapeutics, Inc. |
Analysis of mrna heterogeneity and stability
|
US20160032273A1
(en)
|
2013-03-15 |
2016-02-04 |
Moderna Therapeutics, Inc. |
Characterization of mrna molecules
|
US8980864B2
(en)
|
2013-03-15 |
2015-03-17 |
Moderna Therapeutics, Inc. |
Compositions and methods of altering cholesterol levels
|
PL3019619T3
(pl)
|
2013-07-11 |
2022-01-10 |
Modernatx, Inc. |
Kompozycje zawierające syntetyczne polinkleotydy kodujące białka powiązane z crispr i syntetyczne sgrna oraz sposoby ich stosowania
|
WO2015034928A1
(en)
|
2013-09-03 |
2015-03-12 |
Moderna Therapeutics, Inc. |
Chimeric polynucleotides
|
WO2015034925A1
(en)
|
2013-09-03 |
2015-03-12 |
Moderna Therapeutics, Inc. |
Circular polynucleotides
|
EP3043826A4
(en)
|
2013-09-13 |
2017-05-24 |
Moderna Therapeutics, Inc. |
Polynucleotide compositions containing amino acids
|
EP3052106A4
(en)
|
2013-09-30 |
2017-07-19 |
ModernaTX, Inc. |
Polynucleotides encoding immune modulating polypeptides
|
EP3052521A1
(en)
|
2013-10-03 |
2016-08-10 |
Moderna Therapeutics, Inc. |
Polynucleotides encoding low density lipoprotein receptor
|
EP3058082A4
(en)
|
2013-10-18 |
2017-04-26 |
ModernaTX, Inc. |
Compositions and methods for tolerizing cellular systems
|
EP3092250A4
(en)
|
2014-01-08 |
2017-05-24 |
Moderna Therapeutics, Inc. |
Polynucleotides for the in vivo production of antibodies
|
EP3159407A1
(en)
*
|
2015-10-23 |
2017-04-26 |
Silence Therapeutics (London) Ltd |
Guide rnas, methods and uses
|
CA3003267A1
(en)
*
|
2015-10-26 |
2017-05-04 |
Translate Bio Ma, Inc. |
Nanoparticle formulations for delivery of nucleic acid complexes
|
CN110719954B
(zh)
|
2017-05-31 |
2023-12-26 |
奥特吉尼克斯制药公司 |
用于iii型糖原贮积病的治疗剂
|
EP3648791A1
(en)
*
|
2017-07-04 |
2020-05-13 |
CureVac AG |
Novel nucleic acid molecules
|
CA3134271A1
(en)
*
|
2019-03-28 |
2020-10-01 |
Intellia Therapeutics, Inc. |
Compositions and methods comprising a ttr guide rna and a polynucleotide encoding an rna-guided dna binding agent
|
JP2023535225A
(ja)
*
|
2020-07-24 |
2023-08-16 |
ストランド セラピューティクス インコーポレイテッド |
改変ヌクレオチドを含む脂質ナノ粒子
|