IS7385A - Fjölgervingar klópídógrelhýdróklóríðs og notkun þeirra sem andsegaefnasambanda - Google Patents
Fjölgervingar klópídógrelhýdróklóríðs og notkun þeirra sem andsegaefnasambandaInfo
- Publication number
- IS7385A IS7385A IS7385A IS7385A IS7385A IS 7385 A IS7385 A IS 7385A IS 7385 A IS7385 A IS 7385A IS 7385 A IS7385 A IS 7385A IS 7385 A IS7385 A IS 7385A
- Authority
- IS
- Iceland
- Prior art keywords
- antioxidants
- clopidogrel hydrochloride
- synthetics
- multiple synthetics
- clopidogrel
- Prior art date
Links
- 239000003963 antioxidant agent Substances 0.000 title 1
- 229950010560 clopidogrel hydrochloride Drugs 0.000 title 1
- XIHVAFJSGWDBGA-RSAXXLAASA-N methyl (2s)-2-(2-chlorophenyl)-2-(6,7-dihydro-4h-thieno[3,2-c]pyridin-5-yl)acetate;hydrochloride Chemical compound Cl.C1([C@H](N2CC=3C=CSC=3CC2)C(=O)OC)=CC=CC=C1Cl XIHVAFJSGWDBGA-RSAXXLAASA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU0200438A HUP0200438A3 (en) | 2002-02-06 | 2002-02-06 | Novel clopidogrel hydrochloride polymorphs, process for the preparation thereof, their use and pharmaceutical compositions containing them |
PCT/HU2002/000157 WO2003066637A1 (en) | 2002-02-06 | 2002-12-20 | Polymorphs of clopidogrel hydrochloride and their use as antithrombic compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
IS7385A true IS7385A (is) | 2004-08-05 |
Family
ID=89980128
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IS7385A IS7385A (is) | 2002-02-06 | 2004-08-05 | Fjölgervingar klópídógrelhýdróklóríðs og notkun þeirra sem andsegaefnasambanda |
Country Status (15)
Country | Link |
---|---|
US (1) | US20050113406A1 (is) |
EP (1) | EP1474427A1 (is) |
JP (1) | JP2005522441A (is) |
KR (1) | KR20040079987A (is) |
AU (1) | AU2002353251A1 (is) |
BG (1) | BG108868A (is) |
CZ (1) | CZ2004901A3 (is) |
EA (1) | EA007119B1 (is) |
HR (1) | HRP20040741A2 (is) |
HU (1) | HUP0200438A3 (is) |
IS (1) | IS7385A (is) |
PL (1) | PL370038A1 (is) |
SK (1) | SK3362004A3 (is) |
WO (1) | WO2003066637A1 (is) |
YU (1) | YU69604A (is) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0321256D0 (en) | 2003-09-11 | 2003-10-08 | Generics Uk Ltd | Novel crystalline compounds |
EP1713812A1 (en) * | 2004-01-13 | 2006-10-25 | Zentiva, a.s. | New crystalline forms of clopidogrel hydrobromide and methods of their preparation |
WO2005104663A2 (en) * | 2004-03-05 | 2005-11-10 | Ipca Laboratories Limited | Industrial process for preparation of clopidogrel hydrogen sulphate |
RU2328501C1 (ru) * | 2004-04-09 | 2008-07-10 | Ханми Фарм. Ко., ЛТД | Кристаллический клопидогрель нафталинсульфонат или его гидрат, способ его получения и содержащая его фармацевтическая композиция |
CN1997647A (zh) * | 2004-04-20 | 2007-07-11 | 赛诺菲-安万特 | 氯吡格雷盐及其多晶型物 |
CA2562507A1 (en) * | 2004-04-20 | 2005-11-03 | Sanofi-Aventis | Polymorphic forms of methyl(+)-(s)-alpha-(2-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4h) acetate hydrobromide, clopidrogel hydrobromide |
WO2005117866A1 (en) * | 2004-06-01 | 2005-12-15 | Ivax Pharmaceuticals S.R.O. | Amorphous clopidogrel hydrochloride and its antithrombotic use |
EP1674468A1 (en) * | 2004-12-21 | 2006-06-28 | Ratiopharm GmbH | Polymorphs of clopidogrel hydrobromide |
EP1693375A1 (en) * | 2005-02-21 | 2006-08-23 | KRKA, tovarna zdravil, d.d., Novo mesto | Process for preparing clopidrogel hydrogen sulfate of form I |
WO2007029096A2 (en) * | 2005-09-05 | 2007-03-15 | Ranbaxy Laboratories Limited | Novel polymorphic forms of clopidogrel hydrochloride |
WO2007029080A1 (en) * | 2005-09-05 | 2007-03-15 | Ranbaxy Laboratories Limited | Preparation of form i of clopidogrel hydrochloride |
KR20070066518A (ko) * | 2005-12-22 | 2007-06-27 | 에스케이케미칼주식회사 | 고체상 반응을 이용한 (s)-(+)-클로피도그렐의 제조방법 |
KR101235117B1 (ko) * | 2005-12-26 | 2013-02-20 | 에스케이케미칼주식회사 | 광학분리에 의한 (s)-(+)-클로피도그렐의 제조방법 |
KR100742134B1 (ko) * | 2006-02-07 | 2007-07-24 | 경동제약 주식회사 | 결정성S-(+)-메틸-2-(2-클로로페닐)-2-(6,7-디히드로티에노[3,2-c]피리딘-5(4H)-일)아세테이트·캄실레이트를 포함하는약학적 조성물 |
WO2008004249A2 (en) * | 2006-07-04 | 2008-01-10 | Msn Laboratories Limited | An improved process for the preparation of clopidogrel and its pharmaceutically acceptable salts |
US20100062066A1 (en) * | 2006-11-14 | 2010-03-11 | Acusphere, Inc | Formulations of Tetrahydropyridine Antiplatelet Agents for Parenteral or Oral Administration |
EP1970054A3 (en) | 2007-03-14 | 2009-06-03 | Ranbaxy Laboratories Limited | Clopidogrel tablets |
US8343995B2 (en) | 2007-04-27 | 2013-01-01 | Cydex Pharmaceuticals, Inc. | Formulations containing clopidogrel and sulfoalkyl ether cyclodextrin and methods of use |
US7985859B2 (en) * | 2007-05-30 | 2011-07-26 | Wockhardt Ltd. | Processes for the preparation of clopidogrel |
EP2107061A1 (en) | 2008-04-02 | 2009-10-07 | Krka Tovarna Zdravil, D.D., Novo Mesto | Process for the preparation of optically enriched clopidogrel |
KR20190071006A (ko) | 2009-05-13 | 2019-06-21 | 사이덱스 파마슈티칼스, 인크. | 프라수그렐 및 사이클로덱스트린 유도체를 포함하는 약학 조성물 및 그의 제조 및 사용 방법 |
CN102120745B (zh) * | 2011-01-31 | 2013-04-10 | 天津红日药业股份有限公司 | 一种盐酸氯吡格雷的晶型ⅰ及其制备方法和用途 |
WO2012123958A1 (en) | 2011-02-14 | 2012-09-20 | Cadila Healthcare Limited | Highly pure salts of clopidogrel free of genotoxic impurities |
CN102367257B (zh) * | 2011-11-21 | 2014-05-07 | 天津红日药业股份有限公司 | 氯吡格雷盐酸盐的单晶晶型,它们的制备及应用 |
HUP1400294A2 (hu) | 2014-06-13 | 2015-12-28 | Skillpharm Kft | Clopidogrel új alkalmazása |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2530247B1 (fr) * | 1982-07-13 | 1986-05-16 | Sanofi Sa | Nouveaux derives de la thieno (3, 2-c) pyridine, leur procede de preparation et leur application therapeutique |
FR2623810B2 (fr) * | 1987-02-17 | 1992-01-24 | Sanofi Sa | Sels de l'alpha-(tetrahydro-4,5,6,7 thieno(3,2-c) pyridyl-5) (chloro-2 phenyl) -acetate de methyle dextrogyre et compositions pharmaceutiques en contenant |
US5189170A (en) * | 1989-09-29 | 1993-02-23 | Sanofi | Process for the preparation of phenylacetic derivatives of thieno-pyridines |
FR2664596B1 (fr) * | 1990-07-10 | 1994-06-10 | Sanofi Sa | Procede de preparation d'un derive n-phenylacetique de tetrahydrothieno [3,2-c] pyridine et son intermediaire de synthese. |
HU225504B1 (en) * | 1997-05-13 | 2007-01-29 | Sanofi Aventis | Novel halophenyl-(2-(2-thienyl)-ethylamino)-acetonitriles and process for producing them |
FR2779726B1 (fr) * | 1998-06-15 | 2001-05-18 | Sanofi Sa | Forme polymorphe de l'hydrogenosulfate de clopidogrel |
HU226421B1 (en) * | 1998-11-09 | 2008-12-29 | Sanofi Aventis | Process for racemizing optically active 2-(2-chlorophenyl)-2-(2-(2-thienyl)-ethylamino)-acetamides |
-
2002
- 2002-02-06 HU HU0200438A patent/HUP0200438A3/hu unknown
- 2002-12-20 JP JP2003566010A patent/JP2005522441A/ja active Pending
- 2002-12-20 PL PL02370038A patent/PL370038A1/xx unknown
- 2002-12-20 AU AU2002353251A patent/AU2002353251A1/en not_active Abandoned
- 2002-12-20 KR KR10-2004-7012110A patent/KR20040079987A/ko not_active Application Discontinuation
- 2002-12-20 WO PCT/HU2002/000157 patent/WO2003066637A1/en not_active Application Discontinuation
- 2002-12-20 US US10/504,042 patent/US20050113406A1/en not_active Abandoned
- 2002-12-20 SK SK336-2004A patent/SK3362004A3/sk not_active Application Discontinuation
- 2002-12-20 YU YU69604A patent/YU69604A/sh unknown
- 2002-12-20 EP EP02788271A patent/EP1474427A1/en not_active Withdrawn
- 2002-12-20 EA EA200401025A patent/EA007119B1/ru not_active IP Right Cessation
- 2002-12-20 CZ CZ2004901A patent/CZ2004901A3/cs unknown
-
2004
- 2004-08-05 IS IS7385A patent/IS7385A/is unknown
- 2004-08-17 HR HRP20040741 patent/HRP20040741A2/xx not_active Application Discontinuation
- 2004-09-03 BG BG108868A patent/BG108868A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
AU2002353251A1 (en) | 2003-09-02 |
KR20040079987A (ko) | 2004-09-16 |
EP1474427A1 (en) | 2004-11-10 |
HU0200438D0 (en) | 2002-04-29 |
EA200401025A1 (ru) | 2004-12-30 |
WO2003066637A1 (en) | 2003-08-14 |
US20050113406A1 (en) | 2005-05-26 |
CZ2004901A3 (cs) | 2005-02-16 |
JP2005522441A (ja) | 2005-07-28 |
HRP20040741A2 (en) | 2004-12-31 |
HUP0200438A3 (en) | 2003-10-28 |
HUP0200438A2 (hu) | 2003-09-29 |
YU69604A (sh) | 2006-08-17 |
BG108868A (en) | 2005-09-30 |
EA007119B1 (ru) | 2006-06-30 |
PL370038A1 (en) | 2005-05-16 |
SK3362004A3 (sk) | 2005-03-04 |
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