ZA996667B - Dihydro-and tetrahydro-quinoline compounds, a process for their preparation and pharmaceutical compositions containing them. - Google Patents
Dihydro-and tetrahydro-quinoline compounds, a process for their preparation and pharmaceutical compositions containing them.Info
- Publication number
- ZA996667B ZA996667B ZA9906667A ZA996667A ZA996667B ZA 996667 B ZA996667 B ZA 996667B ZA 9906667 A ZA9906667 A ZA 9906667A ZA 996667 A ZA996667 A ZA 996667A ZA 996667 B ZA996667 B ZA 996667B
- Authority
- ZA
- South Africa
- Prior art keywords
- alkyl
- optionally substituted
- cycloalkyl
- aryl
- heterocycloalkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/04—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
- C07D215/06—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms having only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/20—Spiro-condensed ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Ophthalmology & Optometry (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Quinoline Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Materials For Medical Uses (AREA)
- Anti-Oxidant Or Stabilizer Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9813306A FR2784988B1 (fr) | 1998-10-23 | 1998-10-23 | Nouveaux composes dihydro et tetrahydroquinoleiniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA996667B true ZA996667B (en) | 2000-05-02 |
Family
ID=9531911
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA9906667A ZA996667B (en) | 1998-10-23 | 1999-10-22 | Dihydro-and tetrahydro-quinoline compounds, a process for their preparation and pharmaceutical compositions containing them. |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US6350759B1 (xx) |
| EP (1) | EP0995743B1 (xx) |
| JP (1) | JP3159971B2 (xx) |
| KR (1) | KR100421074B1 (xx) |
| CN (1) | CN1255493A (xx) |
| AT (1) | ATE236129T1 (xx) |
| AU (1) | AU753044B2 (xx) |
| BR (1) | BR9905587A (xx) |
| CA (1) | CA2287046C (xx) |
| DE (1) | DE69906445T2 (xx) |
| DK (1) | DK0995743T3 (xx) |
| EA (1) | EA003272B1 (xx) |
| ES (1) | ES2196742T3 (xx) |
| FR (1) | FR2784988B1 (xx) |
| NO (1) | NO313590B1 (xx) |
| NZ (1) | NZ500574A (xx) |
| PL (1) | PL336139A1 (xx) |
| PT (1) | PT995743E (xx) |
| SI (1) | SI0995743T1 (xx) |
| ZA (1) | ZA996667B (xx) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6703384B2 (en) | 1998-09-23 | 2004-03-09 | Research Development Foundation | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof |
| CA2399802C (en) * | 2000-02-11 | 2009-12-08 | Research Development Foundation | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof |
| WO2002047610A2 (en) * | 2000-11-16 | 2002-06-20 | The Regents Of The University Of California | Marine actinomycete taxon for drug and fermentation product dicovery |
| KR100488444B1 (ko) * | 2001-12-31 | 2005-05-11 | 한국과학기술연구원 | 퀴놀론 유도체 및 그 제조 방법 |
| US7176232B2 (en) | 2002-06-24 | 2007-02-13 | The Regents Of The University Of California | Salinosporamides and methods for use thereof |
| US7919497B2 (en) * | 2002-08-02 | 2011-04-05 | Nereus Pharmaceuticals, Inc. | Analogs of dehydrophenylahistins and their therapeutic use |
| IL166628A0 (en) * | 2002-08-02 | 2006-01-15 | Nereus Pharmaceuticals Inc | Dehydrophenyl lahistins and analogs thereof and the synthesis of dehydrophenyllahistins and analogs thereof |
| US7935704B2 (en) * | 2003-08-01 | 2011-05-03 | Nereus Pharmaceuticals, Inc. | Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof |
| AU2003296908A1 (en) * | 2002-09-27 | 2004-05-04 | Nereus Pharmaceuticals, Inc. | Macrocyclic lactams |
| EP1617844A4 (en) * | 2003-04-03 | 2009-07-22 | Prana Biotechnology Ltd | TREATMENT OF NEUROLOGICAL DISEASES |
| ZA200600473B (en) * | 2003-06-20 | 2007-04-25 | Univ California | Salinosporamides and methods for use thereof |
| DE602004031614D1 (de) * | 2003-06-20 | 2011-04-14 | Nereus Pharmaceuticals Inc | Verwendung von (3.2.0) heterocyclischen verbindungen und ihren analoga zur behandlung von krebs |
| KR20060132698A (ko) * | 2004-01-23 | 2006-12-21 | 니리어스 파마슈티컬즈, 인코퍼레이션 | 항균제로 유용한 비스-인돌 피롤 |
| US7579371B2 (en) | 2004-04-30 | 2009-08-25 | Nereus Pharmaceuticals, Inc. | Methods of using [3.2.0] heterocyclic compounds and analogs thereof |
| BRPI0509824A (pt) * | 2004-04-30 | 2007-10-09 | Nereus Pharmaceuticals Inc | compostos heterocìclicos [3.2.0] e métodos de uso dos mesmos |
| CN103230394B (zh) * | 2004-12-03 | 2016-04-20 | 达纳-法伯癌症研究公司 | 治疗肿瘤性疾病的化合物及其用途 |
| US7576094B2 (en) * | 2004-12-13 | 2009-08-18 | Eli Lilly And Company | Spiro derivatives as lipoxygenase inhibitors |
| NZ572026A (en) | 2006-04-06 | 2011-12-22 | Nereus Pharmaceuticals Inc | Total synthesis of salinosporamide a and analogs thereof |
| US8129527B2 (en) * | 2006-11-03 | 2012-03-06 | Nereus Pharmacuticals, Inc. | Analogs of dehydrophenylahistins and their therapeutic use |
| WO2008095195A2 (en) * | 2007-02-02 | 2008-08-07 | Nereus Pharmaceuticals, Inc. | Lyophilized formulations of salinosporamide a |
| TWI366565B (en) * | 2007-06-06 | 2012-06-21 | Otsuka Pharma Co Ltd | Quinolone compound and pharmaceutical composition |
| US8394816B2 (en) * | 2007-12-07 | 2013-03-12 | Irene Ghobrial | Methods of using [3.2.0] heterocyclic compounds and analogs thereof in treating Waldenstrom's Macroglobulinemia |
| EP2276765A4 (en) * | 2008-05-12 | 2011-10-19 | Nereus Pharmaceuticals Inc | SALINOSPORAMIDE DERIVATIVES AS PROTEASOMAL HEMMER |
| JP5247667B2 (ja) * | 2008-12-05 | 2013-07-24 | 大塚製薬株式会社 | 医薬 |
| KR101053329B1 (ko) | 2009-07-09 | 2011-08-01 | 삼성전기주식회사 | 세라믹 전자부품 |
| CN102958919A (zh) * | 2010-07-02 | 2013-03-06 | 霍夫曼-拉罗奇有限公司 | 新的四氢喹啉衍生物 |
| CN103159676B (zh) * | 2011-12-16 | 2015-07-15 | 卢忠林 | 一种式i化合物的制备方法 |
| US8835643B2 (en) | 2012-02-23 | 2014-09-16 | Empire Technology Development Llc | Molecules, compositions, and methods for light absorption |
| SG10201901242PA (en) | 2014-09-14 | 2019-03-28 | Avanir Pharmaceuticals Inc | Pharmaceutical compositions comprising a dextromethorphan compound and quinidine for the treatment of agitation in dementia |
| US10238650B2 (en) | 2015-03-06 | 2019-03-26 | Beyondspring Pharmaceuticals, Inc. | Method of treating cancer associated with a RAS mutation |
| US10076518B2 (en) | 2015-03-06 | 2018-09-18 | Beyondspring Pharmaceuticals, Inc. | Method of treating a brain tumor |
| MX2018000451A (es) | 2015-07-13 | 2018-05-07 | Beyondspring Pharmaceuticals Inc | Composiciones de plinabulina. |
| RU2753543C1 (ru) | 2016-02-08 | 2021-08-17 | Бейондспринг Фармасьютикалс, Инк. | Композиции, содержащие тукаресол или его аналоги |
| CN107304184A (zh) * | 2016-04-18 | 2017-10-31 | 诺华丝国际股份有限公司 | 用于从取代的1,2‑二氢喹啉除去污染物的方法 |
| WO2017214052A1 (en) | 2016-06-06 | 2017-12-14 | Beyondspring Pharmaceuticals, Inc. | Composition and method for reducing neutropenia |
| WO2018129381A1 (en) | 2017-01-06 | 2018-07-12 | Beyondspring Pharmaceuticals, Inc. | Tubulin binding compounds and therapeutic use thereof |
| JP2020514412A (ja) | 2017-02-01 | 2020-05-21 | ビヨンドスプリング ファーマシューティカルズ，インコーポレイテッド | 好中球減少症の低減方法 |
| CN109553575B (zh) * | 2017-09-27 | 2022-06-03 | 泰兴瑞泰化工有限公司 | 一种高纯乙氧基喹啉的吸附除杂方法 |
| KR20200112881A (ko) | 2018-01-24 | 2020-10-05 | 비욘드스프링 파마수티컬스, 인코포레이티드. | 플리나불린의 투여를 통해 혈소판감소증을 감소시키는 조성물 및 방법 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3331846A (en) * | 1963-08-28 | 1967-07-18 | Lilly Co Eli | Metal catalyst process for converting alpha-amino-acetylenes to dihydroquinoline |
| IL51342A (en) * | 1977-01-27 | 1980-11-30 | Abic Ltd | Ethoxyquin derivatives,their preparation and pharmaceutical and veterinary compositions comprising them |
| GB8816269D0 (en) * | 1988-07-08 | 1988-08-10 | Int Assn Of Fish Meal Manufact | Compounds for use as anti-oxidants in fish meal/fish oil |
| US5696130A (en) * | 1994-12-22 | 1997-12-09 | Ligand Pharmaceuticals Incorporated | Tricyclic steroid receptor modulator compounds and methods |
| JPH09301953A (ja) * | 1996-03-12 | 1997-11-25 | Sanwa Kagaku Kenkyusho Co Ltd | マロン酸ジアミド誘導体及びその用途 |
-
1998
- 1998-10-23 FR FR9813306A patent/FR2784988B1/fr not_active Expired - Fee Related
-
1999
- 1999-10-20 CA CA002287046A patent/CA2287046C/fr not_active Expired - Fee Related
- 1999-10-21 PL PL99336139A patent/PL336139A1/xx not_active Application Discontinuation
- 1999-10-21 JP JP29930399A patent/JP3159971B2/ja not_active Expired - Fee Related
- 1999-10-22 ZA ZA9906667A patent/ZA996667B/xx unknown
- 1999-10-22 CN CN99125591A patent/CN1255493A/zh active Pending
- 1999-10-22 NZ NZ500574A patent/NZ500574A/en unknown
- 1999-10-22 AT AT99402624T patent/ATE236129T1/de not_active IP Right Cessation
- 1999-10-22 NO NO19995175A patent/NO313590B1/no not_active IP Right Cessation
- 1999-10-22 EP EP99402624A patent/EP0995743B1/fr not_active Expired - Lifetime
- 1999-10-22 ES ES99402624T patent/ES2196742T3/es not_active Expired - Lifetime
- 1999-10-22 BR BR9905587-2A patent/BR9905587A/pt not_active IP Right Cessation
- 1999-10-22 US US09/425,267 patent/US6350759B1/en not_active Expired - Fee Related
- 1999-10-22 DK DK99402624T patent/DK0995743T3/da active
- 1999-10-22 SI SI9930251T patent/SI0995743T1/xx unknown
- 1999-10-22 AU AU56009/99A patent/AU753044B2/en not_active Ceased
- 1999-10-22 EA EA199900865A patent/EA003272B1/ru not_active IP Right Cessation
- 1999-10-22 DE DE69906445T patent/DE69906445T2/de not_active Expired - Fee Related
- 1999-10-22 PT PT99402624T patent/PT995743E/pt unknown
- 1999-10-23 KR KR10-1999-0046162A patent/KR100421074B1/ko not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69906445T2 (de) | 2004-04-08 |
| EP0995743B1 (fr) | 2003-04-02 |
| PT995743E (pt) | 2003-07-31 |
| JP3159971B2 (ja) | 2001-04-23 |
| AU753044B2 (en) | 2002-10-03 |
| EA199900865A2 (ru) | 2000-04-24 |
| JP2000128865A (ja) | 2000-05-09 |
| FR2784988A1 (fr) | 2000-04-28 |
| DK0995743T3 (da) | 2003-07-21 |
| KR20000029268A (ko) | 2000-05-25 |
| NO995175L (no) | 2000-04-25 |
| DE69906445D1 (de) | 2003-05-08 |
| NO995175D0 (no) | 1999-10-22 |
| PL336139A1 (en) | 2000-04-25 |
| NO313590B1 (no) | 2002-10-28 |
| AU5600999A (en) | 2000-05-04 |
| EA003272B1 (ru) | 2003-02-27 |
| NZ500574A (en) | 2000-08-25 |
| CA2287046A1 (fr) | 2000-04-23 |
| US6350759B1 (en) | 2002-02-26 |
| FR2784988B1 (fr) | 2002-09-20 |
| ES2196742T3 (es) | 2003-12-16 |
| CN1255493A (zh) | 2000-06-07 |
| SI0995743T1 (en) | 2003-08-31 |
| EA199900865A3 (ru) | 2000-10-30 |
| CA2287046C (fr) | 2003-12-02 |
| BR9905587A (pt) | 2001-12-11 |
| EP0995743A1 (fr) | 2000-04-26 |
| ATE236129T1 (de) | 2003-04-15 |
| KR100421074B1 (ko) | 2004-03-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ZA996667B (en) | Dihydro-and tetrahydro-quinoline compounds, a process for their preparation and pharmaceutical compositions containing them. | |
| AU5062996A (en) | Novel pyridine compounds, processes for their preparation and the pharmaceutical compositions which contain them | |
| NZ334954A (en) | Substituted heterocycles as anti-tumor agents | |
| HU904956D0 (en) | Process for producing benzopyrane derivatives and pharmaceutical preparatives containing such active agents | |
| NZ503912A (en) | Piperidinylaminomethyl trifluoromethyl cyclic ether compounds and their use as substance P antagonists | |
| NZ236293A (en) | 1-(alkyl or alkoxyalkyl)-4-phenyl piperidine-4-carboxylic acid amide derivatives; preparatory processes and pharmaceutical compositions | |
| AU1054200A (en) | Neurological disorders | |
| MY120237A (en) | Method for the synthesis of quinoline derivatives | |
| HUP9903783A2 (hu) | Dihidro- és tetrahidrokinolinszármazékok, eljárás előállításukra és ilyen vegyületeket tartalmazó gyógyászati készítmények | |
| IE863374L (en) | Indoles. | |
| HUP0400436A2 (hu) | Új triciklusos dihidrokinolin-vegyületek, eljárás a vegyületek előállítására és a vegyületeket tartalmazó gyógyászati készítmények | |
| MY131141A (en) | N-benzyl-indoles, processes for their preparation and pharmaceutical compositions containing them. | |
| AU6288700A (en) | Novel benzo[f]naphthyridine, preparation and compositions containing them | |
| DE69803648T2 (de) | Metalloproteaseinhibitoren, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen | |
| ES2085234A1 (es) | Agente activo sobre el sistema nervioso central, procedimiento para su preparacion y composiciones farmaceuticas que lo contienen. | |
| ZA200003035B (en) | Compounds of 7-oxo-2,3,7,14-tetrahydro-1H-benzo[B]-pyrano[3,2-H] acridin carboxylate, a process for their preparation and pharmaceutical compositions containing them. | |
| HK1038741A1 (en) | New substituted (dihydro) benzoxayine and (dihydro) benzothiazine compounds, a process for their preparation and pharmaceutical compositions containing them. | |
| GB9906328D0 (en) | 2-Substituted RNA preparation | |
| IL109396A0 (en) | Pyrido (1,2,3-DE) quinoxaline derivatives, pharmaceutical compositions containing the same and processes for the preparation thereof | |
| ES8302719A1 (es) | Un procedimiento para preparar compuestos de cefem | |
| HK1024244A1 (en) | 8h-thieno-(2,3-b)pyrrolizin-8-one compounds, a process for their preir preparation and pharmaceutical compositions containing them | |
| IL147767A0 (en) | Processes for the preparation of 2-arylvinyl alkyl ether and 1,4-diaryl-2-fluoro-2-butene compounds | |
| AU1773497A (en) | Novel 2,3-benzodiazepine derivatives | |
| TH51098B (th) | อนุพันธุ์ของควินโนลีนในฐานะที่เป็นอัลฟา-1 แอนตาโกนิสต์ |