ZA985095B - Rapamycin formulations for oral administration. - Google Patents

Rapamycin formulations for oral administration.

Info

Publication number
ZA985095B
ZA985095B ZA9805095A ZA985095A ZA985095B ZA 985095 B ZA985095 B ZA 985095B ZA 9805095 A ZA9805095 A ZA 9805095A ZA 985095 A ZA985095 A ZA 985095A ZA 985095 B ZA985095 B ZA 985095B
Authority
ZA
South Africa
Prior art keywords
oral administration
rapamycin formulations
rapamycin
formulations
oral
Prior art date
Application number
ZA9805095A
Other languages
English (en)
Inventor
Arwinder Singh Nagi
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of ZA985095B publication Critical patent/ZA985095B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ZA9805095A 1997-06-13 1998-06-11 Rapamycin formulations for oral administration. ZA985095B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US87496597A 1997-06-13 1997-06-13

Publications (1)

Publication Number Publication Date
ZA985095B true ZA985095B (en) 1999-12-13

Family

ID=25364977

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9805095A ZA985095B (en) 1997-06-13 1998-06-11 Rapamycin formulations for oral administration.

Country Status (26)

Country Link
EP (1) EP0994697B1 (zh)
JP (1) JP2002504124A (zh)
KR (1) KR20010013650A (zh)
CN (1) CN1133424C (zh)
AR (1) AR012971A1 (zh)
AT (1) ATE283687T1 (zh)
AU (1) AU743584B2 (zh)
BR (1) BR9810746A (zh)
CA (1) CA2293793C (zh)
CZ (1) CZ295276B6 (zh)
DE (1) DE69827947T2 (zh)
DK (1) DK0994697T3 (zh)
ES (1) ES2232948T3 (zh)
HU (1) HUP0003341A3 (zh)
IL (1) IL132986A0 (zh)
NO (1) NO996044D0 (zh)
NZ (1) NZ501652A (zh)
PL (1) PL337320A1 (zh)
PT (1) PT994697E (zh)
RU (1) RU2184541C2 (zh)
SK (1) SK284472B6 (zh)
TR (1) TR199903065T2 (zh)
TW (1) TW574040B (zh)
UA (1) UA65573C2 (zh)
WO (1) WO1998056358A1 (zh)
ZA (1) ZA985095B (zh)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH686761A5 (de) 1993-05-27 1996-06-28 Sandoz Ag Galenische Formulierungen.
US20020013335A1 (en) * 2000-06-16 2002-01-31 American Home Products Corporation Method of treating cardiovascular disease
EP1709974A3 (en) * 2000-06-16 2006-12-06 Wyeth Method of treating cardiovascular disease using rapamycin
US6670355B2 (en) 2000-06-16 2003-12-30 Wyeth Method of treating cardiovascular disease
JP4969747B2 (ja) * 2001-01-19 2012-07-04 武田薬品工業株式会社 錠剤フィルムコーティング用組成物
GB0123400D0 (en) 2001-09-28 2001-11-21 Novartis Ag Organic compounds
EA008379B1 (ru) 2002-02-01 2007-04-27 Ариад Джин Терапьютикс, Инк. Фосфорсодержащие соединения и их применения
GB0602632D0 (en) * 2006-02-08 2006-03-22 Pliva Istrazivacki Inst D O O Preparation Of A Solid Dosage From Comprising Tacrolimus And/Or Sirolimus
CN102138903B (zh) * 2011-03-17 2012-12-12 苏州特瑞药业有限公司 一种依维莫司固体口服药物组合物
CN110585159B (zh) * 2019-09-12 2021-11-02 杭州华东医药集团新药研究院有限公司 一种含有西罗莫司的片剂
CN116236453A (zh) * 2023-02-08 2023-06-09 江苏和汇医药科技有限公司 一种延长药品释放的糖包衣及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0525960T3 (da) * 1991-06-18 1996-04-15 American Home Prod Anvendelse af rapamycin til behandling af T-celle leukæmi/lymfon
US5352783A (en) * 1993-06-09 1994-10-04 Merck & Co., Inc. Microbial transformation product having immunosuppressive activity
IL111004A (en) * 1993-09-30 1998-06-15 American Home Prod Oral formulations of rapamycin
US5536729A (en) * 1993-09-30 1996-07-16 American Home Products Corporation Rapamycin formulations for oral administration
US5547948A (en) * 1995-01-17 1996-08-20 American Home Products Corporation Controlled release of steroids from sugar coatings
CA2230748C (en) * 1997-03-14 2010-08-03 American Home Products Corporation Rapamycin formulations for oral administration

Also Published As

Publication number Publication date
DE69827947D1 (de) 2005-01-05
DE69827947T2 (de) 2005-04-21
IL132986A0 (en) 2001-03-19
NO996044L (no) 1999-12-08
KR20010013650A (ko) 2001-02-26
AU743584B2 (en) 2002-01-31
TR199903065T2 (xx) 2000-09-21
SK171799A3 (en) 2000-07-11
CZ295276B6 (cs) 2005-06-15
TW574040B (en) 2004-02-01
CN1259864A (zh) 2000-07-12
JP2002504124A (ja) 2002-02-05
BR9810746A (pt) 2000-09-19
PT994697E (pt) 2005-02-28
HUP0003341A2 (hu) 2001-02-28
CN1133424C (zh) 2004-01-07
EP0994697A1 (en) 2000-04-26
HUP0003341A3 (en) 2001-03-28
WO1998056358A1 (en) 1998-12-17
PL337320A1 (en) 2000-08-14
ATE283687T1 (de) 2004-12-15
SK284472B6 (sk) 2005-04-01
AU7836898A (en) 1998-12-30
EP0994697B1 (en) 2004-12-01
AR012971A1 (es) 2000-11-22
ES2232948T3 (es) 2005-06-01
NO996044D0 (no) 1999-12-08
UA65573C2 (uk) 2004-04-15
CA2293793A1 (en) 1998-12-17
CZ450299A3 (cs) 2000-08-16
RU2184541C2 (ru) 2002-07-10
CA2293793C (en) 2006-07-11
DK0994697T3 (da) 2005-02-14
NZ501652A (en) 2001-09-28

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