HUP0003341A2 - Orális adagolásra alkalmas rapamicinkészítmények - Google Patents

Orális adagolásra alkalmas rapamicinkészítmények

Info

Publication number
HUP0003341A2
HUP0003341A2 HU0003341A HUP0003341A HUP0003341A2 HU P0003341 A2 HUP0003341 A2 HU P0003341A2 HU 0003341 A HU0003341 A HU 0003341A HU P0003341 A HUP0003341 A HU P0003341A HU P0003341 A2 HUP0003341 A2 HU P0003341A2
Authority
HU
Hungary
Prior art keywords
oral administration
rapamycin
rapamycin formulations
formulations
sugar coating
Prior art date
Application number
HU0003341A
Other languages
English (en)
Inventor
Arwinder Singh Nagi
Original Assignee
American Home Products Corp.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Products Corp. filed Critical American Home Products Corp.
Publication of HUP0003341A2 publication Critical patent/HUP0003341A2/hu
Publication of HUP0003341A3 publication Critical patent/HUP0003341A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

A találmány rapamicin szilárd dózisegységre vonatkozik, amely egymagból és egy cukorbevonatból áll, ahol a cukorbevonat rapamicint, egyvagy több cukrot és egy vagy több kötőanyagot tartalmaz. Ó
HU0003341A 1997-06-13 1998-06-11 Rapamycin formulations for oral administration HUP0003341A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US87496597A 1997-06-13 1997-06-13

Publications (2)

Publication Number Publication Date
HUP0003341A2 true HUP0003341A2 (hu) 2001-02-28
HUP0003341A3 HUP0003341A3 (en) 2001-03-28

Family

ID=25364977

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0003341A HUP0003341A3 (en) 1997-06-13 1998-06-11 Rapamycin formulations for oral administration

Country Status (26)

Country Link
EP (1) EP0994697B1 (hu)
JP (1) JP2002504124A (hu)
KR (1) KR20010013650A (hu)
CN (1) CN1133424C (hu)
AR (1) AR012971A1 (hu)
AT (1) ATE283687T1 (hu)
AU (1) AU743584B2 (hu)
BR (1) BR9810746A (hu)
CA (1) CA2293793C (hu)
CZ (1) CZ295276B6 (hu)
DE (1) DE69827947T2 (hu)
DK (1) DK0994697T3 (hu)
ES (1) ES2232948T3 (hu)
HU (1) HUP0003341A3 (hu)
IL (1) IL132986A0 (hu)
NO (1) NO996044L (hu)
NZ (1) NZ501652A (hu)
PL (1) PL337320A1 (hu)
PT (1) PT994697E (hu)
RU (1) RU2184541C2 (hu)
SK (1) SK284472B6 (hu)
TR (1) TR199903065T2 (hu)
TW (1) TW574040B (hu)
UA (1) UA65573C2 (hu)
WO (1) WO1998056358A1 (hu)
ZA (1) ZA985095B (hu)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH686761A5 (de) 1993-05-27 1996-06-28 Sandoz Ag Galenische Formulierungen.
US6670355B2 (en) 2000-06-16 2003-12-30 Wyeth Method of treating cardiovascular disease
EP1709974A3 (en) * 2000-06-16 2006-12-06 Wyeth Method of treating cardiovascular disease using rapamycin
US20020013335A1 (en) * 2000-06-16 2002-01-31 American Home Products Corporation Method of treating cardiovascular disease
JP4969747B2 (ja) * 2001-01-19 2012-07-04 武田薬品工業株式会社 錠剤フィルムコーティング用組成物
GB0123400D0 (en) 2001-09-28 2001-11-21 Novartis Ag Organic compounds
ES2485841T3 (es) 2002-02-01 2014-08-14 Ariad Pharmaceuticals, Inc Compuestos que contienen fósforo y usos de los mismos
GB0602632D0 (en) * 2006-02-08 2006-03-22 Pliva Istrazivacki Inst D O O Preparation Of A Solid Dosage From Comprising Tacrolimus And/Or Sirolimus
CN102138903B (zh) * 2011-03-17 2012-12-12 苏州特瑞药业有限公司 一种依维莫司固体口服药物组合物
CN110585159B (zh) * 2019-09-12 2021-11-02 杭州华东医药集团新药研究院有限公司 一种含有西罗莫司的片剂
CN116236453A (zh) * 2023-02-08 2023-06-09 江苏和汇医药科技有限公司 一种延长药品释放的糖包衣及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69209183T2 (de) * 1991-06-18 1996-08-08 American Home Prod Verwendung von Rapamycin zur Behandlung von T-Zellen Lymphom/Leukämie bei Erwachsenen
US5352783A (en) * 1993-06-09 1994-10-04 Merck & Co., Inc. Microbial transformation product having immunosuppressive activity
IL111004A (en) * 1993-09-30 1998-06-15 American Home Prod Oral formulations of rapamycin
US5536729A (en) * 1993-09-30 1996-07-16 American Home Products Corporation Rapamycin formulations for oral administration
US5547948A (en) * 1995-01-17 1996-08-20 American Home Products Corporation Controlled release of steroids from sugar coatings
CA2230748C (en) * 1997-03-14 2010-08-03 American Home Products Corporation Rapamycin formulations for oral administration

Also Published As

Publication number Publication date
PT994697E (pt) 2005-02-28
NO996044D0 (no) 1999-12-08
KR20010013650A (ko) 2001-02-26
DK0994697T3 (da) 2005-02-14
DE69827947T2 (de) 2005-04-21
ZA985095B (en) 1999-12-13
AR012971A1 (es) 2000-11-22
TW574040B (en) 2004-02-01
UA65573C2 (uk) 2004-04-15
CZ450299A3 (cs) 2000-08-16
EP0994697A1 (en) 2000-04-26
CA2293793A1 (en) 1998-12-17
WO1998056358A1 (en) 1998-12-17
EP0994697B1 (en) 2004-12-01
BR9810746A (pt) 2000-09-19
HUP0003341A3 (en) 2001-03-28
DE69827947D1 (de) 2005-01-05
CZ295276B6 (cs) 2005-06-15
AU743584B2 (en) 2002-01-31
NO996044L (no) 1999-12-08
CA2293793C (en) 2006-07-11
CN1259864A (zh) 2000-07-12
CN1133424C (zh) 2004-01-07
ES2232948T3 (es) 2005-06-01
SK171799A3 (en) 2000-07-11
ATE283687T1 (de) 2004-12-15
JP2002504124A (ja) 2002-02-05
AU7836898A (en) 1998-12-30
PL337320A1 (en) 2000-08-14
NZ501652A (en) 2001-09-28
IL132986A0 (en) 2001-03-19
RU2184541C2 (ru) 2002-07-10
SK284472B6 (sk) 2005-04-01
TR199903065T2 (xx) 2000-09-21

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